Statistical analysis on object data presents many challenges. Basic summaries such as means and variances are difficult to compute. We apply ideas from topology to study object data. We present a framework for using death vectors and persistence landscapes to vectorize object data and perform statistical analysis. We apply this method to some common leaf images that were previously shown to be challenging to compare using a 3D shape techniques. Surprisingly, the most persistent features are shown to be “topological noise” and the statistical analysis depends on the less persistent features which we refer to as the “geometric signal”. We also describe the first steps to a new approach to using topology for object data analysis, which applies topology to distributions on object spaces. We introduce a new Frechet-Morse function technique for probability distribution on a compact object space, extending the Frechet means lo a larger number of location parameters, including Frechet antimeans. An example of 3D data analysis to distinguish two flowers using the new location parameters associated with a Veronese-Whitney (VW) embedding of random projective shapes of 3D configurations extracted from a set of pairs of their digital camera images is also given here.
Our approach and results are closely related to work by (2016) @cite_22 , who also applied TDA to object data. In their case they considered brain artery structures extracted from magnetic resonance images and applied persistence homology, which was encoded in vectors by the order statistic on the most persistent points in the persistence diagram. Also, closely related is work by Kovacev- (2016) @cite_28 who applied persistent homology and persistence landscapes to protein structure data.
@cite_28 @cite_22
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Persistent homology captures the evolution of topological features of a model as a parameter changes. The most commonly used summary statistics of persistent homology are the barcode and the persistence diagram. Another summary statistic, the persistence landscape, was recently introduced by Bubenik. It is a functional summary, so it is easy to calculate sample means and variances, and it is straightforward to construct various test statistics. Implementing a permutation test we detect conformational changes between closed and open forms of the maltose-binding protein, a large biomolecule consisting of 370 amino acid residues. Furthermore, persistence landscapes can be applied to machine learning methods. A hyperplane from a support vector machine shows the clear separation between the closed and open proteins conformations. Moreover, because our approach captures dynamical properties of the protein our results may help in identifying residues susceptible to ligand binding; we show that the majority of active site residues and allosteric pathway residues are located in the vicinity of the most persistent loop in the corresponding filtered Vietoris-Rips complex. This finding was not observed in the classical anisotropic network model. Persistence diagrams, which summarize the birth and death of homological features extracted from data, are employed as stable signatures for applications in image analysis and other areas. Besides simply considering the multiset of intervals included in a persistence diagram, some applications need to find representative cycles for the intervals. In this paper, we address the problem of computing these representative cycles, termed as persistent 1-cycles. The definition of persistent cycles is based on the interval module decomposition of persistence modules, which reveals the structure of persistent homology. After showing that the computation of the optimal persistent 1-cycles is NP-hard, we propose an alternative set of meaningful persistent 1-cycles that can be computed with an efficient polynomial time algorithm. We also inspect the stability issues of the optimal persistent 1-cycles and the persistent 1-cycles computed by our algorithm with the observation that the perturbations of both cannot be properly bounded. We design a software which applies our algorithm to various datasets. Experiments on 3D point clouds, mineral structures, and images show the effectiveness of our algorithm in practice. Topological data analysis (TDA) is an emerging mathematical concept for characterizing shapes in complex data. In TDA, persistence diagrams are widely recognized as a useful descriptor of data, and can distinguish robust and noisy topological properties. This paper proposes a kernel method on persistence diagrams to develop a statistical framework in TDA. The proposed kernel satisfies the stability property and provides explicit control on the effect of persistence. Furthermore, the method allows a fast approximation technique. The method is applied into practical data on proteins and oxide glasses, and the results show the advantage of our method compared to other relevant methods on persistence diagrams. This work introduces a new dataset and framework for the exploration of topological data analysis (TDA) techniques applied to time-series data. We examine the end-toend TDA processing pipeline for persistent homology applied to time-delay embeddings of time series – embeddings that capture the underlying system dynamics from which time series data is acquired. In particular, we consider stability with respect to time series length, the approximation accuracy of sparse filtration methods, and the discriminating ability of persistence diagrams as a feature for learning. We explore these properties across a wide range of time-series datasets spanning multiple domains for single source multi-segment signals as well as multi-source single segment signals. Our analysis and dataset captures the entire TDA processing pipeline and includes time-delay embeddings, persistence diagrams, topological distance measures, as well as kernels for similarity learning and classification tasks for a broad set of time-series data sources. We outline the TDA framework and rationale behind the dataset and provide insights into the role of TDA for time-series analysis as well as opportunities for new work. Persistent homology probes topological properties from point clouds and functions. By looking at multiple scales simultaneously, one can record the births and deaths of topological features as the scale varies. In this paper we use a statistical technique, the empirical bootstrap, to separate topological signal from topological noise. In particular, we derive condence sets for persistence diagrams and condence bands for persistence landscapes. We present a novel framework for characterizing signals in images using techniques from computational algebraic topology. This technique is general enough for dealing with noisy multivariate data including geometric noise. The main tool is persistent homology which can be encoded in persistence diagrams. These diagrams visually show how the number of connected components of the sublevel sets of the signal changes. The use of local critical values of a function differs from the usual statistical parametric mapping framework, which mainly uses the mean signal in quantifying imaging data. Our proposed method uses all the local critical values in characterizing the signal and by doing so offers a completely new data reduction and analysis framework for quantifying the signal. As an illustration, we apply this method to a 1D simulated signal and 2D cortical thickness data. In case of the latter, extra homological structures are evident in an control group over the autistic group. In this work, we discuss the problem of finding optimal cycles for homology groups of simplicial complexes and for persistent homology of filtrations. We review the linear programming formulation of the optimal homologous cycle problem and its extension to allow for multiple cycles. By inserting these linear programming problems into the persistent homology algorithm, we are able to compute an optimal cycle, that has been optimized at birth, for every persistent interval in the persistent diagram. We explore the evolution of daily returns of four major US stock market indices during the technology crash of 2000, and the financial crisis of 2007-2009. Our methodology is based on topological data analysis (TDA). We use persistence homology to detect and quantify topological patterns that appear in multidimensional time series. Using a sliding window, we extract time-dependent point cloud data sets, to which we associate a topological space. We detect transient loops that appear in this space, and we measure their persistence. This is encoded in real-valued functions referred to as a 'persistence landscapes'. We quantify the temporal changes in persistence landscapes via their @math -norms. We test this procedure on multidimensional time series generated by various non-linear and non-equilibrium models. We find that, in the vicinity of financial meltdowns, the @math -norms exhibit strong growth prior to the primary peak, which ascends during a crash. Remarkably, the average spectral density at low frequencies of the time series of @math -norms of the persistence landscapes demonstrates a strong rising trend for 250 trading days prior to either dotcom crash on 03 10 2000, or to the Lehman bankruptcy on 09 15 2008. Our study suggests that TDA provides a new type of econometric analysis, which goes beyond the standard statistical measures. The method can be used to detect early warning signals of imminent market crashes. We believe that this approach can be used beyond the analysis of financial time series presented here. We develop in this paper a theoretical framework for the topological study of time series data. Broadly speaking, we describe geometrical and topological properties of sliding window embeddings, as seen through the lens of persistent homology. In particular, we show that maximum persistence at the point-cloud level can be used to quantify periodicity at the signal level, prove structural and convergence theorems for the resulting persistence diagrams, and derive estimates for their dependency on window size and embedding dimension. We apply this methodology to quantifying periodicity in synthetic data sets and compare the results with those obtained using state-of-the-art methods in gene expression analysis. We call this new method SW1PerS, which stands for Sliding Windows and 1-Dimensional Persistence Scoring. New representations of tree-structured data objects, using ideas from topological data analysis, enable improved statistical analyses of a population of brain artery trees. A number of representations of each data tree arise from persistence diagrams that quantify branching and looping of vessels at multiple scales. Novel approaches to the statistical analysis, through various summaries of the persistence diagrams, lead to heightened correlations with covariates such as age and sex, relative to earlier analyses of this data set. The correlation with age continues to be signicant even after controlling for correlations from earlier signicant summaries. The goal of this thesis is to bring together two different theories about critical points of a scalar function and their relation to topology: Discrete Morse theory and Persistent homology. While the goals and fundamental techniques are different, there are certain themes appearing in both theories that closely resemble each other. In certain cases, the two threads can be joined, leading to new insights beyond the classical realm of one particular theory.Discrete Morse theory provides combinatorial equivalents of several core concepts of classical Morse theory, such as discrete Morse functions, discrete gradient vector fields, critical points, and a cancelation theorem for the elimination of critical points of a vector field. Because of its simplicity, it not only maintains the intuition of the classical theory but allows to surpass it in a certain sense by providing explicit and canonical constructions that would become quite complicated in the smooth setting.Persistent homology quantifies topological features of a function. It defines the birth and death of homology classes at critical points, identifies pairs of these (persistence pairs), and provides a quantitative notion of their stability (persistence).Whereas (discrete) Morse theory makes statements about the homotopy type of the sublevel sets of a function, persistence is concerned with their homology. While homology is an invariant of homotopy equivalences, the converse is not true: not every map inducing an isomorphism in homology is a homotopy equivalence. In this thesis we establish a connection between both theories and use this combination to solve problems that are not easily accessibly by any single theory alone. In particular, we solve the problem of minimizing the number of critical points of a function on a surface within a certain tolerance from a given input function. Persistence diagrams are important tools in the field of topological data analysis that describe the presence and magnitude of features in a filtered topological space. However, current approaches for comparing a persistence diagram to a set of other persistence diagrams is linear in the number of diagrams or do not offer performance guarantees. In this paper, we apply concepts from locality-sensitive hashing to support approximate nearest neighbor search in the space of persistence diagrams. Given a set @math of @math @math -bounded persistence diagrams, each with at most @math points, we snap-round the points of each diagram to points on a cubical lattice and produce a key for each possible snap-rounding. Specifically, we fix a grid over each diagram at several resolutions and consider the snap-roundings of each diagram to the four nearest lattice points. Then, we propose a data structure with @math levels @math that stores all snap-roundings of each persistence diagram in @math at each resolution. This data structure has size @math to account for varying lattice resolutions as well as snap-roundings and the deletion of points with low persistence. To search for a persistence diagram, we compute a key for a query diagram by snapping each point to a lattice and deleting points of low persistence. Furthermore, as the lattice parameter decreases, searching our data structure yields a six-approximation of the nearest diagram in @math in @math time and a constant factor approximation of the @math th nearest diagram in @math time. A standard way of approximating or discretizing a metric space is by taking its Rips complexes. These approximations for all parameters are often bound together into a filtration, to which we apply the fundamental group or the first homology. We call the resulting object persistence. Recent results demonstrate that persistence of a compact geodesic locally contractible space X carries a lot of geometric information. However, by definition the corresponding Rips complexes have uncountably many vertices. In this paper we show that nonetheless, the whole persistence of X may be obtained by an appropriate finite sample (subset of X), and that persistence of any subset of X is well interleaved with the persistence of X. It follows that the persistence of X is the minimum of persistences obtained by all finite samples. Furthermore, we prove a much improved Stability theorem for such approximations. As a special case we provide for each (r>0 ) a density (s>0 ), so that for each s-dense sample (S X ) the corresponding fundamental group (and the first homology) of the Rips complex of S is isomorphic to the one of X, leading to an improved reconstruction result. We approach the problem of the computation of persistent homology for large datasets by a divide-and-conquer strategy. Dividing the total space into separate but overlapping components, we are able to limit the total memory residency for any part of the computation, while not degrading the overall complexity much. Locally computed persistence information is then merged from the components and their intersections using a spectral sequence generalizing the Mayer-Vietoris long exact sequence. We describe the Mayer-Vietoris spectral sequence and give details on how to compute with it. This allows us to merge local homological data into the global persistent homology. Furthermore, we detail how the classical topology constructions inherent in the spectral sequence adapt to a persistence perspective, as well as describe the techniques from computational commutative algebra necessary for this extension. The resulting computational scheme suggests a parallelization scheme, and we discuss the communication steps involved in this scheme. Furthermore, the computational scheme can also serve as a guideline for which parts of the boundary matrix manipulation need to co-exist in primary memory at any given time allowing for stratified memory access in single-core computation. The spectral sequence viewpoint also provides easy proofs of a homology nerve lemma as well as a persistent homology nerve lemma. In addition, the algebraic tools we develop to approch persistent homology provide a purely algebraic formulation of kernel, image and cokernel persistence (D. Cohen-Steiner, H. Edelsbrunner, J. Harer, and D. Morozov. Persistent homology for kernels, images, and cokernels. In Proceedings of the twentieth Annual ACM-SIAM Symposium on Discrete Algorithms, pages 1011-1020. Society for Industrial and Applied Mathematics, 2009.) Persistence diagrams play a fundamental role in Topological Data Analysis where they are used as topological descriptors of filtrations built on top of data. They consist in discrete multisets of points in the plane @math that can equivalently be seen as discrete measures in @math . When the data come as a random point cloud, these discrete measures become random measures whose expectation is studied in this paper. First, we show that for a wide class of filtrations, including the C ech and Rips-Vietoris filtrations, the expected persistence diagram, that is a deterministic measure on @math , has a density with respect to the Lebesgue measure. Second, building on the previous result we show that the persistence surface recently introduced in [Adams & al., Persistence images: a stable vector representation of persistent homology] can be seen as a kernel estimator of this density. We propose a cross-validation scheme for selecting an optimal bandwidth, which is proven to be a consistent procedure to estimate the density. Many data sets can be viewed as a noisy sampling of an underlying space, and tools from topological data analysis can characterize this structure for the purpose of knowledge discovery. One such tool is persistent homology, which provides a multiscale description of the homological features within a data set. A useful representation of this homological information is a persistence diagram (PD). Efforts have been made to map PDs into spaces with additional structure valuable to machine learning tasks. We convert a PD to a finite-dimensional vector representation which we call a persistence image (PI), and prove the stability of this transformation with respect to small perturbations in the inputs. The discriminatory power of PIs is compared against existing methods, showing significant performance gains. We explore the use of PIs with vector-based machine learning tools, such as linear sparse support vector machines, which identify features containing discriminating topological information. Finally, high accuracy inference of parameter values from the dynamic output of a discrete dynamical system (the linked twist map) and a partial differential equation (the anisotropic Kuramoto-Sivashinsky equation) provide a novel application of the discriminatory power of PIs. Persistent homology is a mathematical tool from topological data analysis. It performs multi-scale analysis on a set of points and identifies clusters, holes, and voids therein. These latter topological structures complement standard feature representations, making persistent homology an attractive feature extractor for artificial intelligence. Research on persistent homology for AI is in its infancy, and is currently hindered by two issues: the lack of an accessible introduction to AI researchers, and the paucity of applications. In response, the first part of this paper presents a tutorial on persistent homology specifically aimed at a broader audience without sacrificing mathematical rigor. The second part contains one of the first applications of persistent homology to natural language processing. Specifically, our Similarity Filtration with Time Skeleton (SIFTS) algorithm identifies holes that can be interpreted as semantic "tie-backs" in a text document, providing a new document structure representation. We illustrate our algorithm on documents ranging from nursery rhymes to novels, and on a corpus with child and adolescent writings. The present paper shows a mathematical formalization of---as well as algorithms and software for computing---volume-optimal cycles. Volume-optimal cycles are useful for understanding geometric features appearing in a persistence diagram. Volume-optimal cycles provide concrete and optimal homologous structures, such as rings or cavities, on a given dataset. The key idea is the optimality on a @math -chain complex for a @math th homology generator. This optimality formalization is suitable for persistent homology. We can solve the optimization problem using linear programming. For an alpha filtration on @math , volume-optimal cycles on an @math st persistence diagram are more efficiently computable using a merge-tree algorithm. The merge-tree algorithm also provides a tree structure on the diagram containing richer information than volume-optimal cycles. The key mathematical idea used here is Alexander duality. Persistent homology is a vital tool for topological data analysis. Previous work has developed some statistical estimators for characteristics of collections of persistence diagrams. However, tools that provide statistical inference for observations that are persistence diagrams are limited. Specifically, there is a need for tests that can assess the strength of evidence against a claim that two samples arise from the same population or process. We propose the use of randomization-style null hypothesis significance tests (NHST) for these situations. The test is based on a loss function that comprises pairwise distances between the elements of each sample and all the elements in the other sample. We use this method to analyze a range of simulated and experimental data. Through these examples we experimentally explore the power of the p-values. Our results show that the randomization-style NHST based on pairwise distances can distinguish between samples from different processes, which suggests that its use for hypothesis tests upon persistence diagrams is reasonable. We demonstrate its application on a real dataset of fMRI data of patients with ADHD. Persistent homology is a multiscale method for analyzing the shape of sets and functions from point cloud data arising from an unknown distribution supported on those sets. When the size of the sample is large, direct computation of the persistent homology is prohibitive due to the combinatorial nature of the existing algorithms. We propose to compute the persistent homology of several subsamples of the data and then combine the resulting estimates. We study the risk of two estimators and we prove that the subsampling approach carries stable topological information while achieving a great reduction in computational complexity.