Arterial spin labeling perfusion MRI is a noninvasive technique for measuring quantitative cerebral blood flow (CBF), but the measurement is subject to a low signal-to-noise-ratio(SNR). Various post-processing methods have been proposed to denoise ASL MRI but only provide moderate improvement. Deep learning (DL) is an emerging technique that can learn the most representative signal from data without prior modeling which can be highly complex and analytically indescribable. The purpose of this study was to assess whether the record breaking performance of DL can be translated into ASL MRI denoising. We used convolutional neural network (CNN) to build the DL ASL denosing model (DL-ASL) to inherently consider the inter-voxel correlations. To better guide DL-ASL training, we incorporated prior knowledge about ASL MRI: the structural similarity between ASL CBF map and grey matter probability map. A relatively large sample data were used to train the model which was subsequently applied to a new set of data for testing. Experimental results showed that DL-ASL achieved state-of-the-art denoising performance for ASL MRI as compared to current routine methods in terms of higher SNR, keeping CBF quantification quality while shorten the acquisition time by 75 , and automatic partial volume correction.
Jain and Seung @cite_1 demonstrated that convolutional neural networks (CNNs) can be used for image denoising and claimed that CNNs have achieved comparable or even superior performance than the MRF methods. @cite_21 proposed to incorporate residual learning and batch normalization learning strategies into very deep CNN for denoising. @cite_23 proposed to use skip-layer connection to symmetrically link convolutional and deconvolutional layers, which is able to train even deeper CNN architecture for denoising. Peng and Fang @cite_7 proposed a wider CNN network which has relatively fewer layers but has larger size and number of filters in each layer. They claimed that for low-level vision tasks, the depth of the network is not the key, while the width of the architecture is more important. They state that for denoising tasks, deep learning denoising models learn prior pixel distribution information from original image and then use the learned filter banks to restore degrade images. Thus, the more concentrated convolutions to capture the prior image distribution from noisy images, the better the denoising performances.
@cite_21 @cite_1 @cite_7 @cite_23
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Image restoration, including image denoising, super resolution, inpainting, and so on, is a well-studied problem in computer vision and image processing, as well as a test bed for low-level image modeling algorithms. In this work, we propose a very deep fully convolutional auto-encoder network for image restoration, which is a encoding-decoding framework with symmetric convolutional-deconvolutional layers. In other words, the network is composed of multiple layers of convolution and de-convolution operators, learning end-to-end mappings from corrupted images to the original ones. The convolutional layers capture the abstraction of image contents while eliminating corruptions. Deconvolutional layers have the capability to upsample the feature maps and recover the image details. To deal with the problem that deeper networks tend to be more difficult to train, we propose to symmetrically link convolutional and deconvolutional layers with skip-layer connections, with which the training converges much faster and attains better results. In this paper, we propose a very deep fully convolutional encoding-decoding framework for image restoration such as denoising and super-resolution. The network is composed of multiple layers of convolution and deconvolution operators, learning end-to-end mappings from corrupted images to the original ones. The convolutional layers act as the feature extractor, which capture the abstraction of image contents while eliminating noises corruptions. Deconvolutional layers are then used to recover the image details. We propose to symmetrically link convolutional and deconvolutional layers with skip-layer connections, with which the training converges much faster and attains a higher-quality local optimum. First, the skip connections allow the signal to be back-propagated to bottom layers directly, and thus tackles the problem of gradient vanishing, making training deep networks easier and achieving restoration performance gains consequently. Second, these skip connections pass image details from convolutional layers to deconvolutional layers, which is beneficial in recovering the original image. Significantly, with the large capacity, we can handle different levels of noises using a single model. Experimental results show that our network achieves better performance than recent state-of-the-art methods. In this paper, we consider numerous low-level vision problems (e.g., edge-preserving filtering and denoising) as recursive image filtering via a hybrid neural network. The network contains several spatially variant recurrent neural networks (RNN) as equivalents of a group of distinct recursive filters for each pixel, and a deep convolutional neural network (CNN) that learns the weights of RNNs. The deep CNN can learn regulations of recurrent propagation for various tasks and effectively guides recurrent propagation over an entire image. The proposed model does not need a large number of convolutional channels nor big kernels to learn features for low-level vision filters. It is significantly smaller and faster in comparison with a deep CNN based image filter. Experimental results show that many low-level vision tasks can be effectively learned and carried out in real-time by the proposed algorithm. The discriminative model learning for image denoising has been recently attracting considerable attentions due to its favorable denoising performance. In this paper, we take one step forward by investigating the construction of feed-forward denoising convolutional neural networks (DnCNNs) to embrace the progress in very deep architecture, learning algorithm, and regularization method into image denoising. Specifically, residual learning and batch normalization are utilized to speed up the training process as well as boost the denoising performance. Different from the existing discriminative denoising models which usually train a specific model for additive white Gaussian noise at a certain noise level, our DnCNN model is able to handle Gaussian denoising with unknown noise level (i.e., blind Gaussian denoising). With the residual learning strategy, DnCNN implicitly removes the latent clean image in the hidden layers. This property motivates us to train a single DnCNN model to tackle with several general image denoising tasks, such as Gaussian denoising, single image super-resolution, and JPEG image deblocking. Our extensive experiments demonstrate that our DnCNN model can not only exhibit high effectiveness in several general image denoising tasks, but also be efficiently implemented by benefiting from GPU computing. Whereas CNNs have demonstrated immense progress in many vision problems, they suffer from a dependence on monumental amounts of labeled training data. On the other hand, dictionary learning does not scale to the size of problems that CNNs can handle, despite being very effective at low-level vision tasks such as denoising and inpainting. Recently, interest has grown in adapting dictionary learning methods for supervised tasks such as classification and inverse problems. We propose two new network layers that are based on dictionary learning: a sparse factorization layer and a convolutional sparse factorization layer, analogous to fully-connected and convolutional layers, respectively. Using our derivations, these layers can be dropped in to existing CNNs, trained together in an end-to-end fashion with back-propagation, and leverage semisupervision in ways classical CNNs cannot. We experimentally compare networks with these two new layers against a baseline CNN. Our results demonstrate that networks with either of the sparse factorization layers are able to outperform classical CNNs when supervised data are few. They also show performance improvements in certain tasks when compared to the CNN with no sparse factorization layers with the same exact number of parameters. In this paper, we propose a very deep fully convolutional encoding-decoding framework for image restoration such as denoising and super-resolution. The network is composed of multiple layers of convolution and de-convolution operators, learning end-to-end mappings from corrupted images to the original ones. The convolutional layers act as the feature extractor, which capture the abstraction of image contents while eliminating noises corruptions. De-convolutional layers are then used to recover the image details. We propose to symmetrically link convolutional and de-convolutional layers with skip-layer connections, with which the training converges much faster and attains a higher-quality local optimum. First, The skip connections allow the signal to be back-propagated to bottom layers directly, and thus tackles the problem of gradient vanishing, making training deep networks easier and achieving restoration performance gains consequently. Second, these skip connections pass image details from convolutional layers to de-convolutional layers, which is beneficial in recovering the original image. Significantly, with the large capacity, we can handle different levels of noises using a single model. Experimental results show that our network achieves better performance than all previously reported state-of-the-art methods. In recent years, we have witnessed the great success of deep learning on various problems both in low and high-level computer visions. The low-level vision problems, including inpainting, deblurring, denoising, super-resolution, and so on, are highly anticipated to occur in machine vision and image processing. Many deep learning based methods have been proposed to solve low-level vision problems. Most researches treat these problems independently; however, most of the time they appear concurrently. Motivated by the success of generative model in the field of image generation, we develop a deep cascade of neural networks to solve the inpainting, deblurring, denoising problems at the same time. Our model contains two networks: inpainting GAN and deblurring-denoising network. Inpainting GAN generates the coarse patches to fill the lost part in damaged image, and the deblurring-denoising network, stacked by a convolutional auto-encoder, will further refine them. Unlike other methods that handle each problem separately, our method jointly optimizes the two sub-networks. Because GAN training is not only unstable but also difficult, we adopt the Wasserstein distance as the loss function of the inpainting GAN and propose a gradual training strategy. Learning from the idea of residual learning, we utilize skip connections to pass image details from input to reconstruction layer. Experimental results have demonstrated that the proposed model can achieve state-of-the-art performance. Through the experiments, we also demonstrated the effectiveness of the cascade architecture. In this paper, we consider a typical image blind denoising problem, which is to remove unknown noise from noisy images. As we all know, discriminative learning based methods, such as DnCNN, can achieve state-of-the-art denoising results, but they are not applicable to this problem due to the lack of paired training data. To tackle the barrier, we propose a novel two-step framework. First, a Generative Adversarial Network (GAN) is trained to estimate the noise distribution over the input noisy images and to generate noise samples. Second, the noise patches sampled from the first step are utilized to construct a paired training dataset, which is used, in turn, to train a deep Convolutional Neural Network (CNN) for denoising. Extensive experiments have been done to demonstrate the superiority of our approach in image blind denoising. While deep convolutional neural networks (CNNs) have achieved impressive success in image denoising with additive white Gaussian noise (AWGN), their performance remains limited on real-world noisy photographs. The main reason is that their learned models are easy to overfit on the simplified AWGN model which deviates severely from the complicated real-world noise model. In order to improve the generalization ability of deep CNN denoisers, we suggest training a convolutional blind denoising network (CBDNet) with more realistic noise model and real-world noisy-clean image pairs. On the one hand, both signal-dependent noise and in-camera signal processing pipeline is considered to synthesize realistic noisy images. On the other hand, real-world noisy photographs and their nearly noise-free counterparts are also included to train our CBDNet. To further provide an interactive strategy to rectify denoising result conveniently, a noise estimation subnetwork with asymmetric learning to suppress under-estimation of noise level is embedded into CBDNet. Extensive experimental results on three datasets of real-world noisy photographs clearly demonstrate the superior performance of CBDNet over state-of-the-arts in terms of quantitative metrics and visual quality. The code has been made available at this https URL. Low-dose computed tomography (LDCT) has attracted major attention in the medical imaging field, since CT-associated X-ray radiation carries health risks for patients. The reduction of the CT radiation dose, however, compromises the signal-to-noise ratio, which affects image quality and diagnostic performance. Recently, deep-learning-based algorithms have achieved promising results in LDCT denoising, especially convolutional neural network (CNN) and generative adversarial network (GAN) architectures. This paper introduces a conveying path-based convolutional encoder-decoder (CPCE) network in 2-D and 3-D configurations within the GAN framework for LDCT denoising. A novel feature of this approach is that an initial 3-D CPCE denoising model can be directly obtained by extending a trained 2-D CNN, which is then fine-tuned to incorporate 3-D spatial information from adjacent slices. Based on the transfer learning from 2-D to 3-D, the 3-D network converges faster and achieves a better denoising performance when compared with a training from scratch. By comparing the CPCE network with recently published work based on the simulated Mayo data set and the real MGH data set, we demonstrate that the 3-D CPCE denoising model has a better performance in that it suppresses image noise and preserves subtle structures. A deep learning approach to blind denoising of images without complete knowledge of the noise statistics is considered. We propose DN-ResNet, which is a deep convolutional neural network (CNN) consisting of several residual blocks (ResBlocks). With cascade training, DN-ResNet is more accurate and more computationally efficient than the state of art denoising networks. An edge-aware loss function is further utilized in training DN-ResNet, so that the denoising results have better perceptive quality compared to conventional loss function. Next, we introduce the depthwise separable DN-ResNet (DS-DN-ResNet) utilizing the proposed Depthwise Seperable ResBlock (DS-ResBlock) instead of standard ResBlock, which has much less computational cost. DS-DN-ResNet is incrementally evolved by replacing the ResBlocks in DN-ResNet by DS-ResBlocks stage by stage. As a result, high accuracy and good computational efficiency are achieved concurrently. Whereas previous state of art deep learning methods focused on denoising either Gaussian or Poisson corrupted images, we consider denoising images having the more practical Poisson with additive Gaussian noise as well. The results show that DN-ResNets are more efficient, robust, and perform better denoising than current state of art deep learning methods, as well as the popular variants of the BM3D algorithm, in cases of blind and non-blind denoising of images corrupted with Poisson, Gaussian or Poisson-Gaussian noise. Our network also works well for other image enhancement task such as compressed image restoration. Conventionally, image denoising and high-level vision tasks are handled separately in computer vision. In this paper, we cope with the two jointly and explore the mutual influence between them. First we propose a convolutional neural network for image denoising which achieves the state-of-the-art performance. Second we propose a deep neural network solution that cascades two modules for image denoising and various high-level tasks, respectively, and use the joint loss for updating only the denoising network via back-propagation. We demonstrate that on one hand, the proposed denoiser has the generality to overcome the performance degradation of different high-level vision tasks. On the other hand, with the guidance of high-level vision information, the denoising network can generate more visually appealing results. To the best of our knowledge, this is the first work investigating the benefit of exploiting image semantics simultaneously for image denoising and high-level vision tasks via deep learning. The code is available online this https URL. Learning acoustic models directly from the raw waveform data with minimal processing is challenging. Current waveform-based models have generally used very few (∼2) convolutional layers, which might be insufficient for building high-level discriminative features. In this work, we propose very deep convolutional neural networks (CNNs) that directly use time-domain waveforms as inputs. Our CNNs, with up to 34 weight layers, are efficient to optimize over very long sequences (e.g., vector of size 32000), necessary for processing acoustic waveforms. This is achieved through batch normalization, residual learning, and a careful design of down-sampling in the initial layers. Our networks are fully convolutional, without the use of fully connected layers and dropout, to maximize representation learning. We use a large receptive field in the first convolutional layer to mimic bandpass filters, but very small receptive fields subsequently to control the model capacity. We demonstrate the performance gains with the deeper models. Our evaluation shows that the CNN with 18 weight layers outperforms the CNN with 3 weight layers by over 15 in absolute accuracy for an environmental sound recognition task and is competitive with the performance of models using log-mel features. This paper presents a page segmentation method for handwritten historical document images based on a Convolutional Neural Network (CNN). We consider page segmentation as a pixel labeling problem, i.e., each pixel is classified as one of the predefined classes. Traditional methods in this area rely on hand-crafted features carefully tuned considering prior knowledge. In contrast, we propose to learn features from raw image pixels using a CNN. While many researchers focus on developing deep CNN architectures to solve different problems, we train a simple CNN with only one convolution layer. We show that the simple architecture achieves competitive results against other deep architectures on different public datasets. Experiments also demonstrate the effectiveness and superiority of the proposed method compared to previous methods. Model-based iterative reconstruction algorithms for low-dose X-ray computed tomography (CT) are computationally expensive. To address this problem, we recently proposed a deep convolutional neural network (CNN) for low-dose X-ray CT and won the second place in 2016 AAPM Low-Dose CT Grand Challenge. However, some of the textures were not fully recovered. To address this problem, here we propose a novel framelet-based denoising algorithm using wavelet residual network which synergistically combines the expressive power of deep learning and the performance guarantee from the framelet-based denoising algorithms. The new algorithms were inspired by the recent interpretation of the deep CNN as a cascaded convolution framelet signal representation. Extensive experimental results confirm that the proposed networks have significantly improved performance and preserve the detail texture of the original images. We adapt the CNN architecture to texture analysis.We introduce an energy layer to discard the overall shape information and focus on texture features.We evaluate the domain transferability and the depth of networks that are from scratch or pretrained.Our network is simpler than a classic CNN and obtains better classification results on texture datasets.We combine our texture CNN to a classic CNN (overall shape analysis) and further improve the results. Deep learning has established many new state of the art solutions in the last decade in areas such as object, scene and speech recognition. In particular Convolutional Neural Network (CNN) is a category of deep learning which obtains excellent results in object detection and recognition tasks. Its architecture is indeed well suited to object analysis by learning and classifying complex (deep) features that represent parts of an object or the object itself. However, some of its features are very similar to texture analysis methods. CNN layers can be thought of as filter banks of complexity increasing with the depth. Filter banks are powerful tools to extract texture features and have been widely used in texture analysis. In this paper we develop a simple network architecture named Texture CNN (T-CNN) which explores this observation. It is built on the idea that the overall shape information extracted by the fully connected layers of a classic CNN is of minor importance in texture analysis. Therefore, we pool an energy measure from the last convolution layer which we connect to a fully connected layer. We show that our approach can improve the performance of a network while greatly reducing the memory usage and computation. Model-based optimization methods and discriminative learning methods have been the two dominant strategies for solving various inverse problems in low-level vision. Typically, those two kinds of methods have their respective merits and drawbacks, e.g., model-based optimization methods are flexible for handling different inverse problems but are usually time-consuming with sophisticated priors for the purpose of good performance, in the meanwhile, discriminative learning methods have fast testing speed but their application range is greatly restricted by the specialized task. Recent works have revealed that, with the aid of variable splitting techniques, denoiser prior can be plugged in as a modular part of model-based optimization methods to solve other inverse problems (e.g., deblurring). Such an integration induces considerable advantage when the denoiser is obtained via discriminative learning. However, the study of integration with fast discriminative denoiser prior is still lacking. To this end, this paper aims to train a set of fast and effective CNN (convolutional neural network) denoisers and integrate them into model-based optimization method to solve other inverse problems. Experimental results demonstrate that the learned set of denoisers can not only achieve promising Gaussian denoising results but also can be used as prior to deliver good performance for various low-level vision applications. Image denoising is an important pre-processing step in medical image analysis. Different algorithms have been proposed in past three decades with varying denoising performances. More recently, having outperformed all conventional methods, deep learning based models have shown a great promise. These methods are however limited for requirement of large training sample size and high computational costs. In this paper we show that using small sample size, denoising autoencoders constructed using convolutional layers can be used for efficient denoising of medical images. Heterogeneous images can be combined to boost sample size for increased denoising performance. Simplest of networks can reconstruct images with corruption levels so high that noise and signal are not differentiable to human eye. Deep learning using convolutional neural networks (CNN) gives state-of-the-art accuracy on many computer vision tasks (e.g. object detection, recognition, segmentation). Convolutions account for over 90 of the processing in CNNs for both inference testing and training, and fully convolutional networks are increasingly being used. To achieve state-of-the-art accuracy requires CNNs with not only a larger number of layers, but also millions of filters weights, and varying shapes (i.e. filter sizes, number of filters, number of channels) as shown in Fig. 14.5.1. For instance, AlexNet [1] uses 2.3 million weights (4.6MB of storage) and requires 666 million MACs per 227×227 image (13kMACs pixel). VGG16 [2] uses 14.7 million weights (29.4MB of storage) and requires 15.3 billion MACs per 224×224 image (306kMACs pixel). The large number of filter weights and channels results in substantial data movement, which consumes significant energy. A very deep convolutional neural network (CNN) has recently achieved great success for image super-resolution (SR) and offered hierarchical features as well. However, most deep CNN based SR models do not make full use of the hierarchical features from the original low-resolution (LR) images, thereby achieving relatively-low performance. In this paper, we propose a novel residual dense network (RDN) to address this problem in image SR. We fully exploit the hierarchical features from all the convolutional layers. Specifically, we propose residual dense block (RDB) to extract abundant local features via dense connected convolutional layers. RDB further allows direct connections from the state of preceding RDB to all the layers of current RDB, leading to a contiguous memory (CM) mechanism. Local feature fusion in RDB is then used to adaptively learn more effective features from preceding and current local features and stabilizes the training of wider network. After fully obtaining dense local features, we use global feature fusion to jointly and adaptively learn global hierarchical features in a holistic way. Experiments on benchmark datasets with different degradation models show that our RDN achieves favorable performance against state-of-the-art methods.