Supervised deep learning relies on the assumption that enough training data is available, which presents a problem for its application to several fields, like medical imaging. On the example of a binary image classification task (breast cancer recognition), we show that pretraining a generative model for meaningful image augmentation helps enhance the performance of the resulting classifier. By augmenting the data, performance on downstream classification tasks could be improved even with a relatively small training set. We show that this "adversarial augmentation" yields promising results compared to classical image augmentation on the example of breast cancer classification.
Generative Adversarial Networks (GANs), proposed by , have shown great potential for generating or modifying images. Many studies focused on image augmentation using GANs @cite_12 @cite_8 @cite_9 . The application to the medical domain is logical, because it is generally difficult to obtain data there, and all datasets are naturally heavily imbalanced. focuses on brain MRI augmentation using paired image-to-image translation similar to the pix2pix approach @cite_28 .
@cite_28 @cite_9 @cite_12 @cite_8
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Medical datasets are often highly imbalanced, over representing common medical problems, and sparsely representing rare problems. We propose simulation of pathology in images to overcome the above limitations. Using chest Xrays as a model medical image, we implement a generative adversarial network (GAN) to create artificial images based upon a modest sized labeled dataset. We employ a combination of real and artificial images to train a deep convolutional neural network (DCNN) to detect pathology across five classes of disease. We furthermore demonstrate that augmenting the original imbalanced dataset with GAN generated images improves performance of chest pathology classification using the proposed DCNN in comparison to the same DCNN trained with the original dataset alone. This improved performance is largely attributed to balancing of the dataset using GAN generated images, where image classes that are lacking in example images are preferentially augmented. It is a difficult task to classify images with multiple class labels using only a small number of labeled examples, especially when the label (class) distribution is imbalanced. Emotion classification is such an example of imbalanced label distribution, because some classes of emotions like are relatively rare comparing to other labels like happy or sad . In this paper, we propose a data augmentation method using generative adversarial networks (GAN). It can complement and complete the data manifold and find better margins between neighboring classes. Specifically, we design a framework with a CNN model as the classifier and a cycle-consistent adversarial networks (CycleGAN) as the generator. In order to avoid gradient vanishing problem, we employ the least-squared loss as adversarial loss. We also propose several evaluation methods on three benchmark datasets to validate GAN's performance. Empirical results show that we can obtain 5 10 increase in the classification accuracy after employing the GAN-based data augmentation techniques. Conditional Generative Adversarial Networks (GANs) for cross-domain image-to-image translation have made much progress recently [7, 8, 21, 12, 4, 18]. Depending on the task complexity, thousands to millions of labeled image pairs are needed to train a conditional GAN. However, human labeling is expensive, even impractical, and large quantities of data may not always be available. Inspired by dual learning from natural language translation [23], we develop a novel dual-GAN mechanism, which enables image translators to be trained from two sets of unlabeled images from two domains. In our architecture, the primal GAN learns to translate images from domain U to those in domain V, while the dual GAN learns to invert the task. The closed loop made by the primal and dual tasks allows images from either domain to be translated and then reconstructed. Hence a loss function that accounts for the reconstruction error of images can be used to train the translators. Experiments on multiple image translation tasks with unlabeled data show considerable performance gain of DualGAN over a single GAN. For some tasks, DualGAN can even achieve comparable or slightly better results than conditional GAN trained on fully labeled data. Abstract Deep learning methods, and in particular convolutional neural networks (CNNs), have led to an enormous breakthrough in a wide range of computer vision tasks, primarily by using large-scale annotated datasets. However, obtaining such datasets in the medical domain remains a challenge. In this paper, we present methods for generating synthetic medical images using recently presented deep learning Generative Adversarial Networks (GANs). Furthermore, we show that generated medical images can be used for synthetic data augmentation, and improve the performance of CNN for medical image classification. Our novel method is demonstrated on a limited dataset of computed tomography (CT) images of 182 liver lesions (53 cysts, 64 metastases and 65 hemangiomas). We first exploit GAN architectures for synthesizing high quality liver lesion ROIs. Then we present a novel scheme for liver lesion classification using CNN. Finally, we train the CNN using classic data augmentation and our synthetic data augmentation and compare performance. In addition, we explore the quality of our synthesized examples using visualization and expert assessment. The classification performance using only classic data augmentation yielded 78.6 sensitivity and 88.4 specificity. By adding the synthetic data augmentation the results increased to 85.7 sensitivity and 92.4 specificity. We believe that this approach to synthetic data augmentation can generalize to other medical classification applications and thus support radiologists’ efforts to improve diagnosis. Medical imaging datasets are limited in size due to privacy issues and the high cost of obtaining annotations. Augmentation is a widely used practice in deep learning to enrich the data in data-limited scenarios and to avoid overfitting. However, standard augmentation methods that produce new examples of data by varying lighting, field of view, and spatial rigid transformations do not capture the biological variance of medical imaging data and could result in unrealistic images. Generative adversarial networks (GANs) provide an avenue to understand the underlying structure of image data which can then be utilized to generate new realistic samples. In this work, we investigate the use of GANs for producing chest X-ray images to augment a dataset. This dataset is then used to train a convolutional neural network to classify images for cardiovascular abnormalities. We compare our augmentation strategy with traditional data augmentation and show higher accuracy for normal vs abnormal classification in chest X-rays. Image classification datasets are often imbalanced, characteristic that negatively affects the accuracy of deep-learning classifiers. In this work we propose balancing GAN (BAGAN) as an augmentation tool to restore balance in imbalanced datasets. This is challenging because the few minority-class images may not be enough to train a GAN. We overcome this issue by including during the adversarial training all available images of majority and minority classes. The generative model learns useful features from majority classes and uses these to generate images for minority classes. We apply class conditioning in the latent space to drive the generation process towards a target class. The generator in the GAN is initialized with the encoder module of an autoencoder that enables us to learn an accurate class-conditioning in the latent space. We compare the proposed methodology with state-of-the-art GANs and demonstrate that BAGAN generates images of superior quality when trained with an imbalanced dataset. Unsupervised image translation, which aims in translating two independent sets of images, is challenging in discovering the correct correspondences without paired data. Existing works build upon Generative Adversarial Network (GAN) such that the distribution of the translated images are indistinguishable from the distribution of the target set. However, such set-level constraints cannot learn the instance-level correspondences (e.g. aligned semantic parts in object configuration task). This limitation often results in false positives (e.g. geometric or semantic artifacts), and further leads to mode collapse problem. To address the above issues, we propose a novel framework for instance-level image translation by Deep Attention GAN (DA-GAN). Such a design enables DA-GAN to decompose the task of translating samples from two sets into translating instances in a highly-structured latent space. Specifically, we jointly learn a deep attention encoder, and the instancelevel correspondences could be consequently discovered through attending on the learned instance pairs. Therefore, the constraints could be exploited on both set-level and instance-level. Comparisons against several state-ofthe- arts demonstrate the superiority of our approach, and the broad application capability, e.g, pose morphing, data augmentation, etc., pushes the margin of domain translation problem. In this paper we investigate the feasibility of using synthetic data to augment face datasets. In particular, we propose a novel generative adversarial network (GAN) that can disentangle identity-related attributes from non-identity-related attributes. This is done by training an embedding network that maps discrete identity labels to an identity latent space that follows a simple prior distribution, and training a GAN conditioned on samples from that distribution. Our proposed GAN allows us to augment face datasets by generating both synthetic images of subjects in the training set and synthetic images of new subjects not in the training set. By using recent advances in GAN training, we show that the synthetic images generated by our model are photo-realistic, and that training with augmented datasets can indeed increase the accuracy of face recognition models as compared with models trained with real images alone. Unsupervised image translation, which aims in translating two independent sets of images, is challenging in discovering the correct correspondences without paired data. Existing works build upon Generative Adversarial Networks (GANs) such that the distribution of the translated images are indistinguishable from the distribution of the target set. However, such set-level constraints cannot learn the instance-level correspondences (e.g. aligned semantic parts in object transfiguration task). This limitation often results in false positives (e.g. geometric or semantic artifacts), and further leads to mode collapse problem. To address the above issues, we propose a novel framework for instance-level image translation by Deep Attention GAN (DA-GAN). Such a design enables DA-GAN to decompose the task of translating samples from two sets into translating instances in a highly-structured latent space. Specifically, we jointly learn a deep attention encoder, and the instance-level correspondences could be consequently discovered through attending on the learned instances. Therefore, the constraints could be exploited on both set-level and instance-level. Comparisons against several state-of-the-arts demonstrate the superiority of our approach, and the broad application capability, e.g, pose morphing, data augmentation, etc., pushes the margin of domain translation problem.1 A citing sentence is one that appears in a scientific article and cites previous work. Citing sentences have been studied and used in many applications. For example, they have been used in scientific paper summarization, automatic survey generation, paraphrase identification, and citation function classification. Citing sentences that cite multiple papers are common in scientific writing. This observation should be taken into consideration when using citing sentences in applications. For instance, when a citing sentence is used in a summary of a scientific paper, only the fragments of the sentence that are relevant to the summarized paper should be included in the summary. In this paper, we present and compare three different approaches for identifying the fragments of a citing sentence that are related to a given target reference. Our methods are: word classification, sequence labeling, and segment classification. Our experiments show that segment classification achieves the best results. Conditional Generative Adversarial Networks (GANs) for cross-domain image-to-image translation have made much progress recently. Depending on the task complexity, thousands to millions of labeled image pairs are needed to train a conditional GAN. However, human labeling is expensive, even impractical, and large quantities of data may not always be available. Inspired by dual learning from natural language translation, we develop a novel dual-GAN mechanism, which enables image translators to be trained from two sets of unlabeled images from two domains. In our architecture, the primal GAN learns to translate images from domain U to those in domain V, while the dual GAN learns to invert the task. The closed loop made by the primal and dual tasks allows images from either domain to be translated and then reconstructed. Hence a loss function that accounts for the reconstruction error of images can be used to train the translators. Experiments on multiple image translation tasks with unlabeled data show considerable performance gain of DualGAN over a single GAN. For some tasks, DualGAN can even achieve comparable or slightly better results than conditional GAN trained on fully labeled data. Recently, Image-to-Image Translation (IIT) has achieved great progress in image style transfer and semantic context manipulation for images. However, existing approaches require exhaustively labelling training data, which is labor demanding, difficult to scale up, and hard to adapt to a new domain. To overcome such a key limitation, we propose Sparsely Grouped Generative Adversarial Networks (SG-GAN) as a novel approach that can translate images in sparsely grouped datasets where only a few train samples are labelled. Using a one-input multi-output architecture, SG-GAN is well-suited for tackling multi-task learning and sparsely grouped learning tasks. The new model is able to translate images among multiple groups using only a single trained model. To experimentally validate the advantages of the new model, we apply the proposed method to tackle a series of attribute manipulation tasks for facial images as a case study. Experimental results show that SG-GAN can achieve comparable results with state-of-the-art methods on adequately labelled datasets while attaining a superior image translation quality on sparsely grouped datasets is available at https: github.com zhangqianhui SGGAN-tensorflow.. A Triangle Generative Adversarial Network ( @math -GAN) is developed for semi-supervised cross-domain joint distribution matching, where the training data consists of samples from each domain, and supervision of domain correspondence is provided by only a few paired samples. @math -GAN consists of four neural networks, two generators and two discriminators. The generators are designed to learn the two-way conditional distributions between the two domains, while the discriminators implicitly define a ternary discriminative function, which is trained to distinguish real data pairs and two kinds of fake data pairs. The generators and discriminators are trained together using adversarial learning. Under mild assumptions, in theory the joint distributions characterized by the two generators concentrate to the data distribution. In experiments, three different kinds of domain pairs are considered, image-label, image-image and image-attribute pairs. Experiments on semi-supervised image classification, image-to-image translation and attribute-based image generation demonstrate the superiority of the proposed approach. Recent works showed that Generative Adversarial Networks (GANs) can be successfully applied in unsupervised domain adaptation, where, given a labeled source dataset and an unlabeled target dataset, the goal is to train powerful classifiers for the target samples. In particular, it was shown that a GAN objective function can be used to learn target features indistinguishable from the source ones. In this work, we extend this framework by (i) forcing the learned feature extractor to be domain-invariant, and (ii) training it through data augmentation in the feature space, namely performing feature augmentation. While data augmentation in the image space is a well established technique in deep learning, feature augmentation has not yet received the same level of attention. We accomplish it by means of a feature generator trained by playing the GAN minimax game against source features. Results show that both enforcing domain-invariance and performing feature augmentation lead to superior or comparable performance to state-of-the-art results in several unsupervised domain adaptation benchmarks. This paper describes an intuitive generalization to the Generative Adversarial Networks (GANs) to generate samples while capturing diverse modes of the true data distribution. Firstly, we propose a very simple and intuitive multi-agent GAN architecture that incorporates multiple generators capable of generating samples from high probability modes. Secondly, in order to enforce different generators to generate samples from diverse modes, we propose two extensions to the standard GAN objective function. (1) We augment the generator specific GAN objective function with a diversity enforcing term that encourage different generators to generate diverse samples using a user-defined similarity based function. (2) We modify the discriminator objective function where along with finding the real and fake samples, the discriminator has to predict the generator which generated the given fake sample. Intuitively, in order to succeed in this task, the discriminator must learn to push different generators towards different identifiable modes. Our framework is generalizable in the sense that it can be easily combined with other existing variants of GANs to produce diverse samples. Experimentally we show that our framework is able to produce high quality diverse samples for the challenging tasks such as image face generation and image-to-image translation. We also show that it is capable of learning a better feature representation in an unsupervised setting. We propose a novel GAN-based framework for detecting shadows in images, in which a shadow detection network (D-Net) is trained together with a shadow attenuation network (A-Net) that generates adversarial training examples. The A-Net modifies the original training images constrained by a simplified physical shadow model and is focused on fooling the D-Net’s shadow predictions. Hence, it is effectively augmenting the training data for D-Net with hard-to-predict cases. The D-Net is trained to predict shadows in both original images and generated images from the A-Net. Our experimental results show that the additional training data from A-Net significantly improves the shadow detection accuracy of D-Net. Our method outperforms the state-of-the-art methods on the most challenging shadow detection benchmark (SBU) and also obtains state-of-the-art results on a cross-dataset task, testing on UCF. Furthermore, the proposed method achieves accurate real-time shadow detection at 45 frames per second. In recent years scholars have built maps of science by connecting the academic fields that cite each other, are cited together, or that cite a similar literature. But since scholars cannot always publish in the fields they cite, or that cite them, these science maps are only rough proxies for the potential of a scholar, organization, or country, to enter a new academic field. Here we use a large dataset of scholarly publications disambiguated at the individual level to create a map of science-or research space-where links connect pairs of fields based on the probability that an individual has published in both of them. We find that the research space is a significantly more accurate predictor of the fields that individuals and organizations will enter in the future than citation based science maps. At the country level, however, the research space and citations based science maps are equally accurate. These findings show that data on career trajectories-the set of fields that individuals have previously published in-provide more accurate predictors of future research output for more focalized units-such as individuals or organizations-than citation based science maps. We propose a new recurrent generative adversarial architecture named RNN-GAN to mitigate imbalance data problem in medical image semantic segmentation where the number of pixels belongs to the desired object are significantly lower than those belonging to the background. A model trained with imbalanced data tends to bias towards healthy data which is not desired in clinical applications and predicted outputs by these networks have high precision and low recall. To mitigate imbalanced training data impact, we train RNN-GAN with proposed complementary segmentation mask, in addition, ordinary segmentation masks. The RNN-GAN consists of two components: a generator and a discriminator. The generator is trained on the sequence of medical images to learn corresponding segmentation label map plus proposed complementary label both at a pixel level, while the discriminator is trained to distinguish a segmentation image coming from the ground truth or from the generator network. Both generator and discriminator substituted with bidirectional LSTM units to enhance temporal consistency and get inter and intra-slice representation of the features. We show evidence that the proposed framework is applicable to different types of medical images of varied sizes. In our experiments on ACDC-2017, HVSMR-2016, and LiTS-2017 benchmarks we find consistently improved results, demonstrating the efficacy of our approach. Purpose – The purpose of this paper is to suggest an alternative to the widely used Times Cited criterion for analysing citation networks. The approach involves taking account of the natures of the papers that cite a given paper, so as to differentiate between papers that attract the same number of citations.Design methodology approach – ArticleRank is an algorithm that has been derived from Google's PageRank algorithm to measure the influence of journal articles. ArticleRank is applied to two datasets – a citation network based on an early paper on webometrics, and a self‐citation network based on the 19 most cited papers in the Journal of Documentation – using citation data taken from the Web of Knowledge database.Findings – ArticleRank values provide a different ranking of a set of papers from that provided by the corresponding Times Cited values, and overcomes the inability of the latter to differentiate between papers with the same numbers of citations. The difference in rankings between Times Cited ... Generative Adversarial Networks (GANs) have shown great promise recently in image generation. Training GANs for language generation has proven to be more difficult, because of the non-differentiable nature of generating text with recurrent neural networks. Consequently, past work has either resorted to pre-training with maximum-likelihood or used convolutional networks for generation. In this work, we show that recurrent neural networks can be trained to generate text with GANs from scratch using curriculum learning, by slowly teaching the model to generate sequences of increasing and variable length. We empirically show that our approach vastly improves the quality of generated sequences compared to a convolutional baseline.