Multi-organ segmentation is a critical problem in medical image analysis due to its great value for computer-aided diagnosis, computer-aided surgery, and radiation therapy. Although fully-supervised segmentation methods can achieve good performance, they usually require a large amount of 3D data, such as CT scans, with voxel-wised annotations which are usually difficult, expensive, and slow to obtain. By contrast, large unannotated datasets of CT images are available. Inspired by the well-known semi-supervised learning framework co-training, we propose multi-planar co-training (MPCT), to generate more reliable pseudo-labels by enforcing consistency among multiple planes, i.e., saggital, coronal, and axial planes, of 3D unlabeled medical data, which play a vital role in our framework. Empirical results show that generating pseudo-labels by the multi-planar fusion rather than a single plane leads to a significant performance gain. We evaluate our approach on a new collected dataset and show that MPCT boosts the performance of a typical segmentation model, fully convolutional networks, by a large margin, when only a small set of labeled 3D data is available, i.e., 77.49 vs. 73.14 .
Graph-based semi-supervised methods define a graph where the nodes are labeled and unlabeled examples in the dataset, and edges reflect the similarity of examples. These methods have been widely adopted in non-deep-learning based semi-supervised learning algorithms in the biomedical imaging domain @cite_26 @cite_46 @cite_42 .
@cite_46 @cite_26 @cite_42
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Semi-supervised learning is becoming increasingly important because it can combine data carefully labeled by humans with abundant unlabeled data to train deep neural networks. Classic methods on semi-supervised learning that have focused on transductive learning have not been fully exploited in the inductive framework followed by modern deep learning. The same holds for the manifold assumption---that similar examples should get the same prediction. In this work, we employ a transductive label propagation method that is based on the manifold assumption to make predictions on the entire dataset and use these predictions to generate pseudo-labels for the unlabeled data and train a deep neural network. At the core of the transductive method lies a nearest neighbor graph of the dataset that we create based on the embeddings of the same network.Therefore our learning process iterates between these two steps. We improve performance on several datasets especially in the few labels regime and show that our work is complementary to current state of the art. Multi-label learning refers to the problems where an instance can be assigned to more than one category. In this paper, we present a novel Semi-supervised algorithm for Multi-label learning by solving a Sylvester Equation (SMSE). Two graphs are first constructed on instance level and category level respectively. For instance level, a graph is defined based on both labeled and unlabeled instances, where each node represents one instance and each edge weight reflects the similarity between corresponding pairwise instances. Similarly, for category level, a graph is also built based on all the categories, where each node represents one category and each edge weight reflects the similarity between corresponding pairwise categories. A regularization framework combining two regularization terms for the two graphs is suggested. The regularization term for instance graph measures the smoothness of the labels of instances, and the regularization term for category graph measures the smoothness of the labels of categories. We show that the labels of unlabeled data finally can be obtained by solving a Sylvester Equation. Experiments on RCV1 data set show that SMSE can make full use of the unlabeled data information as well as the correlations among categories and achieve good performance. In addition, we give a SMSEs extended application on collaborative filtering. In many domain adaption formulations, it is assumed to have large amount of unlabeled data from the domain of interest (target domain), some portion of it may be labeled, and large amount of labeled data from other domains, also known as source domain(s). Motivated by the fact that labeled data is hard to obtain in any domain, we design algorithms for the settings in which there exists large amount of unlabeled data from all domains, small portion of which may be labeled. We build on recent advances in graph-based semi-supervised learning and supervised metric learning. Given all instances, labeled and unlabeled, from all domains, we build a large similarity graph between them, where an edge exists between two instances if they are close according to some metric. Instead of using predefined metric, as commonly performed, we feed the labeled instances into metric-learning algorithms and (re)construct a data-dependent metric, which is used to construct the graph. We employ different types of edges depending on the domain-identity of the two vertices touching it, and learn the weights of each edge. Experimental results show that our approach leads to significant reduction in classification error across domains, and performs better than two state-of-the-art models on the task of sentiment classification.