Abstract Survival analysis has been developed and applied in the number of areas including manufacturing, finance, economics and healthcare. In healthcare domain, usually clinical data are high-dimensional, sparse and complex and sometimes there exists few amount of time-to-event (labeled) instances. Therefore building an accurate survival model from electronic health records is challenging. With this motivation, we address this issue and provide a new survival analysis framework using deep learning and active learning with a novel sampling strategy. First, our approach provides better representation with lower dimensions from clinical features using labeled (time-to-event) and unlabeled (censored) instances and then actively trains the survival model by labeling the censored data using an oracle. As a clinical assistive tool, we introduce a simple effective treatment recommendation approach based on our survival model. In the experimental study, we apply our approach on SEER-Medicare data related to prostate cancer among African–Americans and white patients. The results indicate that our approach outperforms significantly than baseline models.
Based on our review, there exist no study to develop a survival analysis approach using both deep learning and active learning. We address this gap in the literature to propose a deep active learning framework for survival analysis. However, There are some studies that develop deep active learning methods for other machine learning tasks. For example, @cite_1 developed a semi-supervised learning framework termed active deep network (ADN) for sentiment analysis. They used restricted Boltzmann machines (RBM) for feature learning based on labeled reviews and large amount of unlabeled reviews, then applied gradient-descent based supervised learning for fine tuning and constructing semi-supervised framework. Finally they used active learning in their framework to improve model performance. In the other study, @cite_5 proposed a deep active learning approach using Deep Belief Network (DBN) for classifying hyperspectral images in remote sensing application. A summary of our review has been illustrated in Table which indicates no research have been developed to address a survival approach using deep learning and active learning.
@cite_5 @cite_1
2518897583 2060099436
Active deep learning classification of hyperspectral images is considered in this paper. Deep learning has achieved success in many applications, but good-quality labeled samples are needed to construct a deep learning network. It is expensive getting good labeled samples in hyperspectral images for remote sensing applications. An active learning algorithm based on a weighted incremental dictionary learning is proposed for such applications. The proposed algorithm selects training samples that maximize two selection criteria, namely representative and uncertainty. This algorithm trains a deep network efficiently by actively selecting training samples at each iteration. The proposed algorithm is applied for the classification of hyperspectral images, and compared with other classification algorithms employing active learning. It is shown that the proposed algorithm is efficient and effective in classifying hyperspectral images. Abstract In natural language processing community, sentiment classification based on insufficient labeled data is a well-known challenging problem. In this paper, a novel semi-supervised learning algorithm called active deep network (ADN) is proposed to address this problem. First, we propose the semi-supervised learning framework of ADN. ADN is constructed by restricted Boltzmann machines (RBM) with unsupervised learning based on labeled reviews and abundant of unlabeled reviews. Then the constructed structure is fine-tuned by gradient-descent based supervised learning with an exponential loss function. Second, in the semi-supervised learning framework, we apply active learning to identify reviews that should be labeled as training data, then using the selected labeled reviews and all unlabeled reviews to train ADN architecture. Moreover, we combine the information density with ADN, and propose information ADN (IADN) method, which can apply the information density of all unlabeled reviews in choosing the manual labeled reviews. Experiments on five sentiment classification datasets show that ADN and IADN outperform classical semi-supervised learning algorithms, and deep learning techniques applied for sentiment classification.