Humans make accurate decisions by interpreting complex data from multiple sources. Medical diagnostics, in particular, often hinge on human interpretation of multi-modal information. In order for artificial intelligence to make progress in automated, objective, and accurate diagnosis and prognosis, methods to fuse information from multiple medical imaging modalities are required. However, combining information from multiple data sources has several challenges, as current deep learning architectures lack the ability to extract useful representations from multimodal information, and often simple concatenation is used to fuse such information. In this work, we propose Multimodal DenseNet, a novel architecture for fusing multimodal data. Instead of focusing on concatenation or early and late fusion, our proposed architectures fuses information over several layers and gives the model flexibility in how it combines information from multiple sources. We apply this architecture to the challenge of polyp characterization and landmark identification in endoscopy. Features from white light images are fused with features from narrow band imaging or depth maps. This study demonstrates that Multimodal DenseNet outperforms monomodal classification as well as other multimodal fusion techniques by a significant margin on two different datasets.
Multimodal machine learning is also used for cross-modal data synthesis. These techniques are particularly prevalent in the medical field, as there are significant cost and privacy barriers in collecting medical data. For example, Huang and Vemulapalli were able to produce synthetic T2 weighted MRI images of the brain from T1 weighted MRI images and vice versa @cite_8 .
@cite_8
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Unsupervised image-to-image translation is an important and challenging problem in computer vision. Given an image in the source domain, the goal is to learn the conditional distribution of corresponding images in the target domain, without seeing any pairs of corresponding images. While this conditional distribution is inherently multimodal, existing approaches make an overly simplified assumption, modeling it as a deterministic one-to-one mapping. As a result, they fail to generate diverse outputs from a given source domain image. To address this limitation, we propose a Multimodal Unsupervised Image-to-image Translation (MUNIT) framework. We assume that the image representation can be decomposed into a content code that is domain-invariant, and a style code that captures domain-specific properties. To translate an image to another domain, we recombine its content code with a random style code sampled from the style space of the target domain. We analyze the proposed framework and establish several theoretical results. Extensive experiments with comparisons to the state-of-the-art approaches further demonstrates the advantage of the proposed framework. Moreover, our framework allows users to control the style of translation outputs by providing an example style image. Code and pretrained models are available at this https URL