Factor analysis provides linear factors that describe relationships between individual variables of a data set. We extend this classical formulation into linear factors that describe relationships between groups of variables, where each group represents either a set of related variables or a data set. The model also naturally extends canonical correlation analysis to more than two sets, in a way that is more flexible than previous extensions. Our solution is formulated as variational inference of a latent variable model with structural sparsity, and it consists of two hierarchical levels: The higher level models the relationships between the groups, whereas the lower models the observed variables given the higher level. We show that the resulting solution solves the group factor analysis problem accurately, outperforming alternative factor analysis based solutions as well as more straightforward implementations of group factor analysis. The method is demonstrated on two life science data sets, one on brain activation and the other on systems biology, illustrating its applicability to the analysis of different types of high-dimensional data sources.
For two groups, @math , the model is equivalent to Bayesian CCA and inter-battery factor analysis @cite_4 ; some factors model the correlations whereas some describe the residual noise within either group.
@cite_4
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Canonical correlation analysis (CCA) is a classical method for seeking correlations between two multivariate data sets. During the last ten years, it has received more and more attention in the machine learning community in the form of novel computational formulations and a plethora of applications. We review recent developments in Bayesian models and inference methods for CCA which are attractive for their potential in hierarchical extensions and for coping with the combination of large dimensionalities and small sample sizes. The existing methods have not been particularly successful in fulfilling the promise yet; we introduce a novel efficient solution that imposes group-wise sparsity to estimate the posterior of an extended model which not only extracts the statistical dependencies (correlations) between data sets but also decomposes the data into shared and data set-specific components. In statistics literature the model is known as inter-battery factor analysis (IBFA), for which we now provide a Bayesian treatment.