Environmental factors that shape biofilm formation
Cells respond to the environment and alter gene expression. Recent studies have revealed the social aspects of bacterial life, such as biofilm formation. Biofilm formation is largely affected by the environment, and the mechanisms by which the gene expression of individual cells affects biofilm development have attracted interest. Environmental factors determine the cell's decision to form or leave a biofilm. In addition, the biofilm structure largely depends on the environment, implying that biofilms are shaped to adapt to local conditions. Second messengers such as cAMP and c di GMP are key factors that link environmental factors with gene regulation. Cell to cell communication is also an important factor in shaping the biofilm. In this short review, we will introduce the basics of biofilm formation and further discuss environmental factors that shape biofilm formation. Finally, the state of the art tools that allow us investigate biofilms under various conditions are discussed. Graphical abstract Environmental factors affect biofilm formation throughout their development.
Bioscience, biotechnology, and biochemistry