Naevus spilus type congenital melanocytic naevus associated with a novel NRAS codon 61 mutation
DEAR EDITOR, We recently described 17 patients with a new subtype of congenital melanocytic nevi (CMN) designated as 'naevus spilus type CMN' The affected patients present with a large caf e au lait background macule and dozens of superimposed small and medium sized CMN. Here we report an additional case with a novel NRAS mutation (Q61L) Congenital melanocytic naevi are categorized by their largest diameter (projected adult size, PAS) Small CMN 1 5 cm PAS) and medium sized CMN (1 5 20 cm PAS) represent rather common, solitary, slightly thickened plaques with prominent terminal hairs. In contrast, large CMN (20 40 cm PAS) and giant CMN 40 cm PAS) are often accompanied by disseminated
The British journal of dermatology