Characterization of programmed cell death 1 ligand (PD L1) expression in circulating tumor cells (CTCs) of lung cancer
conclusively showed catheter position in the centre of SPN (26 cases) NIR spectroscopy probe based forceps were placed at the same place in order to gather tissue information. Mean measurement time was less than one minute after establishing ideal position. Results of spectroscopy measurements from NIR spectroscopy were obtained as differences between spectral characteristics of normal tissue (same side, different lobe) to SPN tissue. Results: The results are expressed as sensitivity of NIR spectroscopy towards EBUS navigated biopsies. Statistical analysis of the results showed very high sensitivity for NIR spectroscopy in confirmation of SPN tissue. From 26 EBUS positive visualisations of SPN there were 26 correct discriminations of SPN tissue, leading to 23 conclusive histological findings. Conclusions: Every confirmatory method brings different information about tissue. EBUS describes volume of the SPN and gives valuable information about the position of catheter in the SPN. NIR spectroscopy brings information about biochemical/ optical characteristics of the tissues. Prototype of intelligent NIR based forceps showed good discriminative ability in the diagnosis of SPN.