Effect of photodynamic therapy for the treatment of halitosis in adolescents a controlled, microbiological, clinical trial.
Halitosis can exert a negative influence on the social relations of adolescents and affect one's self image. The aim of this study was to evaluate the clinical and microbiological effect of antimicrobial photodynamic therapy (aPDT) on halitosis in adolescents. Forty six individuals aged 12 to 19 years were randomly allocated: Group 1 treatment with photodynamic therapy; Group 2 treatment with a tongue scraper and Group 3 treatment with a tongue scraper and photodynamic therapy. The count of bacterial colony forming units per milliliter was used for the microbiological analysis. Statistical analysis involved the Kruskal Wallis test followed by the Student Newman Keuls test. ANOVA was used for the determination of colony forming units after treatment. The level of significance for all statistical tests was 5% (p 0.05) After treatment, a statistically significant reduction in total volatile sulfur compounds was found in all groups (p 0.001) with the largest reduction (median: 0) found in Group 3 (tongue scraper and photodynamic therapy) Moreover, a statistically significant difference was found between treatment with aPDT and a tongue scraper alone (p 0.001) The present findings demonstrate an option for the treatment of halitosis in adolescents, with an immediate effect and without the mechanical aggression to the toungue. Clinical Trials: NCT02007993.
Journal of biophotonics