Evaluation of Age Releated Anti Mullerian Hormone Variations in Domestic Cat
Anti Mullerian hormone (AMH) belongs to the Transforming Growth Factor ss (TGF ss) family and produces only in ovaries by the granulosa cells of growing follicles in females. Therefore the measurement of AMH levels plays an important role for the detection of the presence or absence of the ovaries. The aim of this study was to evaluate the individual AMH levels before and after ovariohysterectomy (OHE) to demonstrate mean AMH alterations in the absence of ovaries with blood sampling in different days after OHE, to demonstrate the age related changes in serum AMH levels and investigate the usability of serum AMH levels as a diagnostic tool for detecting the presence of functional ovarian tissue in domestic cats. Totally 30 domestic cats were used for this study. The animals were allocated into 2 groups according to their ages; <1 year old (Group 1, n=13) and >1 year old (Group 2, n=17) Mean serum AMH concentrations of all cats at day 0 and day 3rd were found 3.15+ 2.25 ng/mL and 0.38+ 0.21 ng/mL respectively. Ten days after surgery, AMH levels of all spayed cats were below the minimum detectable concentration of the ELISA kit <0.08 ng/mL) According to the age classification, the age of cats were correlated with AMH levels at day 0 (rs=0.293, P<0.05) and at day 3 (rs=0.410, P<0.01) It can be concluded that measurement of serum AMH concentrations is adequate for assessing the functional ovarian tissue in cats.