The rational design of specific SOD1 inhibitors via copper coordination and their application in ROS signaling research+ +Electronic supplementary information (ESI) available: Experimental methods and any associated references. Table S1, Fig. S1 S10. See DOI: 10.1039/c6sc01272h
Based on the active site structure and catalytic mechanism of SOD1, we developed a new type of efficient and specific SOD1 inhibitor which can directly change the intracellular levels of H2O2 and O2.
Chemical science