53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration
Meitinger et al. perform a genome wide CRISPR/Cas9 screen for centrinone resistance and identify a 53BP1 USP28 module as critical for communicating mitotic challenges to the p53 circuit and TRIM37 as an enforcer of the singularity of centrosome assembly.
The Journal of cell biology