Tacky cyclic olefin copolymer: a biocompatible bonding technique for the fabrication of microfluidic channels in COC.
Cyclic olefin copolymer (COC) is widely used in microfluidics due to its UV transparency, its biocompatibility and high chemical resistance. Here we present a fast and cost effective solvent bonding technique, which allows for the efficient bonding of protein patterned COC structures. The bonding process is carried out at room temperature and takes less than three minutes. Enzyme activity is retained upon bonding and microstructure deformation does not occur.
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