An Obstetrics Index for the Assessment of Risk Levels of "High Risk Pregnancy" Groups
OBJECTIVE: To validate the usability of "Beksac Obstetrics Index" (BOI/BOIp) in the evaluation of different high risk pregnancy groups. STUDY DESIGN: This study is consisted of 3 groups of patients; 1) Pregnancies without MTHFR polymorphisms (n=65) 2) Pregnancies with methylenetetrahydrofolate reductase (MTHFR; homozygous or compound heterozygous) polymorphisms (n=140) 3) Pregnancies with "autoimmune antibody positivity" without any other type of hereditary thrombophilia (Anti dsDNA, anti phospholipid Ig G/M, anti cardiolipin Ig G/M, ASMA, APA, ENA, anti mitochondrial antibodies) (n=76) In this study, BOI which is (number of child +p/10)/Gravida is used in order to demonstrate the risk levels/scale of different high risk pregnancy groups. RESULTS: The mean BOIp SD) values are 0,41+ 0,22; 0,29+ 0,21; and 0,40+ 0,23 for Control, MTHFR and Autoimmune groups respectively. We have demonstrated statistically significantly decreased BOIp level in MTHFR group compared to the other groups (p:0,002) CONCLUSION: We have demonstrated that BOI/BOIp can be used in the assessment of risk levels of different high risk pregnancy groups.