Potential synthetic adaptogens 1. Synthesis and studies of new N (adamantan 1 yl)methyl]aniline derivatives based on adamantane 1 carbaldehyde
A number of new N (adamantan 1 yl)methyl]aniline derivatives, which can be considered as conformationally labile analogues of synthetic adaptogen Bromantan, were obtained by the reductive amination reaction of adamantane 1 carbaldehyde with aromatic amines. The influence of the reaction conditions of reductive amination on the yield and composition of its products was studied.
Russian Chemical Bulletin