Fabrication of functional PLGA based electrospun scaffolds and their applications in biomedical engineering.
Electrospun PLGA based scaffolds have been applied extensively in biomedical engineering, such as tissue engineering and drug delivery system. Due to lack of the recognition sites on cells, hydropholicity and single function, the applications of PLGA fibrous scaffolds are limited. In order to tackle these issues, many works have been done to obtain functional PLGA based scaffolds, including surface modifications, the fabrication of PLGA based composite scaffolds and drug loaded scaffolds. The functional PLGA based scaffolds have significantly improved cell adhesion, attachment and proliferation. Moreover, the current study has summarized the applications of functional PLGA based scaffolds in wound dressing, vascular and bone tissue engineering area as well as drug delivery system.
Materials science engineering. C, Materials for biological applications