The prevalence of primary dyskinetic ciliary syndromes in patients with sinusitis and bronchiectasis
In this paper are studied the prevalence of this syndrome (the PDCS) in 18 patients affected either of chronic sinusitis or bronchiectasias. Fourteen cases (77%) fulfil the diagnostic requirements in order to be considered as PCDS. Clinical differential features with regard to the idiopathic group are: situs inversus, male's infertility, perennial rhinorrhea and secretory otitis media. Mucociliary transport is studied through an isotopic technique and resulted absent in the PDCS group, being normal in the idiopathic one. The ultrastructure of nasal cilia is normal in the idiopathic representative, while in the cases with PDCS was verified the total or partly lack of dyneine arms in 8 cases, without cilia 3 cases, surnumerary central microtubules 3 cases and surnumerary peripheral microtubules in 2 cases. One sufferer of Kartagener's syndrome showed cilia structure in accordance with standard pattern.