Extracranial orbital meningioma extending into the nasosinus in neurofibromatosis type 2
The purpose of this study was to report a rare case of neurofibromatosis type 2 (NF2) with extracranial orbital meningioma extending into the frontal and ethmoidal sinuses. This is clinical report of a 17-year-old male patient with NF2. Results of an ocular examination, computed tomography scan, and pathological findings of space-occupied orbital and nasosinus lesions are presented. Computed tomography scan revealed a high-density soft tissue mass occupying the right superionasal orbit extending into the frontal and ethmoidal sinuses and bilateral acoustic schwannomas in the brain. Biopsy of the right orbital lesion demonstrated a typical meningioma as indicated with routine hematoxylin-eosin staining and immunohistochemical evaluation. In this patient, an extracranial orbital meningioma, rather than optic nerve sheath meningioma extending into nasosinus, designates a diagnosis of NF2. Ophthalmologists should be aware of the possibility that patients with an extracranial orbital meningioma may also have NF2.