Radiology case of the month
49-year-old female with an anterior mediastinal mass. Castleman's disease is an uncommon benign lymphoproliferative disorder characterized by hypervascular lymphoid hyperplasia. Two distinct histologic variants of Castleman's disease exist - hyaline vascular type and plasma cell type. The etiology is uncertain; however, it is thought to be inflammatory or hamartomatous in nature. Castleman's disease can occur at any age with a peak incidence in the third to fourth decade. This article presents a case of Castleman's disease in a female patient and aims to educate about the natural history, diagnosis, and management of the disease.