Macrophage activation syndrome presenting with pericardial effusion, hyponatremia and renal involvement
Macrophage activation syndrome is a rare and life threatening complication of childhood rheumatic disorders. 6-year-old male child with macrophage activation syndrome complicating systemic onset juvenile idiopathic arthritis. He developed pericardial effusion, hyponatremia and deranged renal function. Improvement on intravenous cortico steroids. High index of suspicion can lead to earlier diagnosis of macrophage activation syndrome.