Synthesis and fungitoxicity of some pyrimidine derivatives
A series of 12 pyrimidine derivatives were prepared and testedin vitro against growth, sporulation and nucleic acid content ofFusarium oxysporum f. sp.lycopersici andHelminthosporium oryzae. Introduction of a thiazole ring together with two aryl groups into 2-aminopyrimidine brought about drastic toxicity for both fungi. Pyrimidine derivatives with aryl groups alone were less toxic. Nitro groups were found to enhance the toxicity of the pyrimidine derivatives especially when substituted in the ortho-position of the aryl groups. Inhibition of nucleic acid synthesis of both fungi was attributed mainly to the presence of the thiazole ring.
Pesticides: Preparation and Mode of Action
Discusses general principles underlying major types of chemical pesticides with a brief history of their development. Emphasizes methods of chemical preparation, uses, biochemical mode of action, and environmental effects. Includes chapters on future developments and on novel methods of pest control such as attractants, chemostimulants, growth hormone chemicals, and microbial insecticides.
Mutiny Echoes: India, Britons, and Charles Dickens's A Tale of Two Cities
This essay asks what, if any, import the Indian ““Mutiny”” of 1857 had on A Tale of Two Cities (1859), Charles Dickens�s fictionalized account of the French Revolution. Begun shortly after the Indian uprising started, Dickens�s historical novel appears studiously to avoid any mention of events on the Indian subcontinent, even though these events preoccupied and enraged the author. Few scholars have attended to the question of A Tale of Two Cities and the ““Mutiny,”” but when they have, scholars have looked for analogies between India and Dickens�s account of the French Revolution. In this essay, by contrast, I examine A Tale of Two Cities in a larger context——of Britons9 response to the Uprising, of Dickens9s short stories and essays in Household Words in the years before the ““Mutiny”” and immediately after, of Dickens9s disenchantment with aspects of British culture, and of his need to articulate a national identity grounded in action. I argue that the events in India were the match that ignited Dickens9s already established midcentury interests in national identity, nobility, and masculine heroism. I do not wish to suggest that A Tale of Two Cities is an Indian ““Mutiny”” novel, but rather that it is a novel about the ““Making of Britons,”” an important endeavor for an author who was intensely dissatisfied with the Britain that he saw around him.