Pharmacognostical Evaluation of Caesalpinia sappan Heartwood
Caesalpinia span heartwood is used in folklore in India. The present work attempts to summarize the pharmacognostical characters of the heartwood of this plant. Ash and extractive values, phytochemical tests, HPTLC and fluorescence analysis were carried out. The present work contributes for the standardization of this medicinal heat wood.
EVALUATION OF ANTI-DIABETIC ACTIVITY OF CAESALPINIA SAPPAN WOOD AGAINST ALLOXAN INDUCED DIABETIC RATS
EVALUATION OF ANTI-DIABETIC ACTIVITY OF CAESALPINIA SAPPAN WOOD AGAINST ALLOXAN INDUCED DIABETIC RATS Suriya Annamalai, Suresh Arumugam, Anju Venugopal, Senthil kumar Natesan JKKMMRF's-Annai JKK Sampoorani Ammal College of Pharmacy, B-Komarapalayam, Namakkal, Tamil Nadu 638183, India. ___________________________________________________________________________ Abstract The Caesalpinia sappan L. (Fabaceae) was authenticated and identified. The aim of this study is to evaluate the anti-diabetic activity of ethanolic extract of Caesalpinia sappan wood in albino wistar rat models (in-vivo) and inhibition of α-glucosidase enzyme method (in-vitro). The ethanol extract dose of 100mg/kg and 200mg/kg was significantly reduced blood glucose levels in diabetic rats after 21 days were evaluated for anti-diabetic activity in alloxan induced diabetic rats. The results were determined by blood parameters and the histopathological study showed significant anti diabetic activity. Invitro method of anti-diabetic activity, the ethanolic extract was prepared 25 μg/ml to 1000μg/ml. The invitro study shown better inhibition of α-glucosidase enzyme was determined by % inhibition. The ethanolic extract of Caesalpinia sappan showed IC50 is 215.95±7.52 and standard drug showed 183.46±5.85. Caesalpinia sappan shows that alkaloids and flavanoids present in this extract may be possibly responsible for the antidiabeic activities.
Application of 2μm Tm Laser on Biomedicine
Continuous wave Thulium laser emits at wavelength of 2.0 mm, which is well suited for tissue ablationand thermally stimulating cutaneous nerves due to its high absorption by water. 2 mm laser can be transmitted suffi-ciently by common quartz fibers and it is safe for eyes. A brief introduction of principle of 2 mm CW Tm Laser is giv-en, analyzing the photothermal modeling of thulium laser-tissue interaction, comparing 2 mm CW Tm Laser with tradi-tional laser.