Rwanda Smallholder Coffee Tree Maintenance and Cherry Processing Techniques: Results of a National Farm-level Survey, 2002
Food Security Research Project (FSRP) and Division of Agricultural Statistics (DSA) Ministry of Agriculture, Livestock and Forestry MINAGRI
Farm-Level Perspectives In Rwanda's Coffee Supply Chain Coordination Challenge
This synthesis shows the need to update and improve household-level information on Rwanda’s coffee sector, so that appropriate policies may be put into place to increase the level and diversity of smallholder and rural business income.
Stereoselective interaction between the R enantiomer of warfarin and cimetidine.
The stereoselectivity of the pharmacokinetic interaction between warfarin and cimetidine was investigated in eight healthy volunteers. The warfarin enantiomers were given separately as single doses (15 mg) alone and during chronic administration of cimetidine (1 g day-1). Cimetidine did not interact with S warfarin but there was an interaction with the R enantiomer of warfarin. Cimetidine caused a significant increase in the mean plasma half-life of R warfarin (from 47.8 h to 57.8 h) and a significant decrease in its mean plasma clearance (from 2.3 to 1.7 ml h-1 kg-1) (P less than 0.02). Administration of a pharmacological dose of vitamin K1 together with the enantiomers of warfarin was necessary clinically and resulted in elevation of vitamin K1 2,3-epoxide concentrations, which were similar in each case.