A new steroidal glycoside from the seeds of Hyoscyamus niger
A new steroidal glycoside hyoscyamoside G (1), together with two known analogues hyoscyamoside E (2) and hyoscyamoside F1 (3), was isolated from the seeds of Hyoscyamus niger. The structure of 1 was established as (22R,24Z)-1α,3β,7β,22,26-pentakishydroxylergost-22-O-β-d-gulcopyranosyl-5,24-diene-26-O-β-d-glucopyranoside, by means of chemical and spectroscopic methods including HRESI-MS, 1D and 2D NMR. In vitro, compound 2 showed cytotoxicity against human lung cancer cell H460 with IC50 value of 66 μg/mL.
Toxicological study of various crude extracts of Hyoscyamus gallagheri native to Oman
Graphical abstract
Geomagnetic micropulsations due to the motion of ocean waves
When sea waves move in the magnetic field of the earth, electric currents are generated in the water volume. These currents give rise to a small magnetic field which perturbs the earth's field. For plane trochoidal waves, this perturbing field decays exponentially with altitude and lies in a vertical plane which is oriented in the direction of wave propagation. The magnitude of the perturbing field also depends upon the magnitude and dip angle of the earth's field, and upon the height, wavelength, and propagation direction of the sea waves. For north-south waves, sea state 5, and an altitude of 100 feet, the perturbation is of the order of 0.1 gamma.