Piperidinecarboxamides with potential CNS and cardiovascular properties.
Several 1- and 2-(2-phenylethyl)piperidinecarboxamides were prepared and subjected to preliminary pharmacological studies. Moderate to strong activity by several compounds was observed in modified dopa potentiation tests in mice.
Chemical and biological weapons in Egypt
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Exopolysaccharide biosynthesis and related enzyme activities of the medicinal fungus, Ganoderma lucidum, grown on lactose in a bioreactor
Exopolysaccharide (EPS) production and biosynthesis were studied in Ganoderma lucidum, a fungus used in traditional Chinese medicine, grown with lactose in a bioreactor. β-Galactosidase activity, which implies the existence of a lactose permease system, was induced by lactose. Lactose feeding also increased α-phosphoglucomutase activity and EPS accumulation but decreased phosphoglucose isomerase activity and lactate concentration in the culture broth. A maximum cell density of 22 g l−1 and EPS at 1.25 g l−1 were obtained in fed-batch bioreactor culture.