Melatonin scavenges phenylglyoxylic ketyl radicals.
The antioxidant properties of melatonin were tested in this work by EPR technique. It was found that melatonin scavenges phenylglyoxylic ketyl radicals. Its effectiveness was 10-times lower than that of vitamin C. A new method of generation of phenylglyoxylic ketyl radicals by spontaneous decomposition of D,L-2,3-diphenyltartaric acid in propan-2-ol was used.
Functional connections between the pineal gland and immune system.
Experimental findings which support a functional connection between the pineal gland and immune system in mammals and birds are summarized. Developmental and age-related changes in pineal gland function appear, at least partially, to be related with immune system efficiency. Mechanisms whereby melatonin influences immune system function are complex, but include participation of mediators (endogenous opioids, cytokines, hormones, zinc pool) as well as specific binding sites on the immune cells. Melatonin, as a highly lyophilic compound, may also penetrate immune cells without mediation of specific receptors and act within as a potent free radical scavenger and as an anti-aging and oncostatic factor. The immune system may, in turn, via synthesis and secretion of soluble factors, cytokines, influence pineal gland function, thereby closing the information loop to maintain homeostasis in order to face the harmful environment.
Immersive haptic interaction with media
New 3D video representations enable new modalities of interaction, such as haptic interaction, with 2D and 3D video for truly immersive media applications. Haptic interaction with video includes haptic structure and haptic motion for new immersive experiences. It is possible to compute haptic structure signals from 3D scene geometry or depth information. This paper introduces the concept of haptic motion, as well as new methods to compute haptic structure and motion signals for 2D video-plus-depth representation. The resulting haptic signals can be rendered using a haptic cursor attached to a 2D or 3D video display.