An Asymmetric Synthetic Approach to the A-ring of the Taxol Family of Anti-Cancer Compounds*
A synthetic route developed for the preparation of the A-ring of Taxol family of molecules is reported. By means of an intramolecular Diels-Alder reaction an asymmetric approach to this ring has been accomplished. Also, initial studies to prepare the A ring using an intramolecular Diels-Alder reaction have been successful.
Synthesis, characterization, and antimicrobial activity of novel substituted 2H-chromenyl acrylates
The present study deals with conventional Witting olefination of 2H-chromene-3-carbaldehydes with stabilized ylide in the presence of dichloromethane to afford (2E)-ethyl-3-(4-chloro-2H-chromen-3-yl) acrylate derivatives. All the products were found to have E-geometry at C=C bond. The synthesized compounds were characterized by spectral data such as IR, 1H NMR and MS. Compounds were screened for antimicrobial activity against strains of gram positive, gram negative bacterial and fungal strains. All compounds showed good antibacterial and antifungal activity.
The Determination of Physicochemical Characteristics of Biodiesel and Its Blending Oils
The viscosity,combustion heat,sulfur content,carbon residue,ash,flash point,moisture and cetane value of biodiesel and its blending oils with diesel were determined.The influence of temperature on the viscosity was studied,and the physicochemical characteristics of biodiesel and its blending oils were compared with diesel.The results indicated that biodiesel and its blending oils had some superior performances and good application prospect.