Olivomycin and related antibiotics XXVIII. Monomeric composition of aureolic acid and proof that the antibiotics LA-7017 and mithramycin are identical to it
Summary1. It has been shown that aureolic acid, antibiotic LA-7017, and mithramycin are identical.2. It has been established that aureolic acid is a glycoside of chromomycinone (I) and contains the monosaccharides D-olivose (II), D-oliose (III), and D-mycarose (IV) in a ratio of 3 : 1 : 1.
The reactions of chromomycinone and derivatives
Abstract The various reactions of chromomycinone, the chromophore of the cancerostatic chromomycins, are described. The structures of several chromomycinone derivatives are also discussed.
Comparative study of the molecular species of chloropropanediol diesters and triacylglycerols in milk fat
In an effort to establish the origin of the fatty acid esters of 3-chloropropanediol, which recently have been isolated in small amounts from goat milk, we compared the molecular species composition of the chlorohydrin diesters and of goat milk triacylglycerols. The chloropropanediol diesters were found to be composed of molecular species containing C10−C18 fatty acids and corresponded closely in carbon number to those calculated for the long chain sn-1,2-diacyl-glycerol moieties of goat milk triacylglycerols. The molecular species of goat milk total triacylglycerols contained C4−C18 fatty acids. It is suggested that triacylglycerols and chloropropanediol diesters are derived from the same pool of long chain fatty acids. A molecular distillate of bovine milk fat did not contain chloropropanediol diesters, while the available samples of human milk fat were shown to contain alkyldiacylglycerols as the major components of a neutral lipid fraction corresponding in polarity to the chloropropanediol diesters.