Improvement in the method for the preparation of N-(3,4-dimethoxyphenylethyl)-3′,4′-dimethoxyphenylacetamide
The synthesis of I was first described in 1909 [i]. At present several methods are known for the preparation of this compound, starting from 3,4-dimethoxyphenylethylamine (If) and 3,4-dimethoxyphenylacetic acid (III) or its acid chloride (IV) [2-4]. The use of IV makes it possible to obtain I in a yield of up to 95% [5, 6], but this method cannot be used industrially because of considerable complications of the industrial process.
Practical preparation of coralyne chloride.
Abstract Coralyne chloride was prepared by a convenient process which can be adapted to large-scale synthesis of this antileukemic alkaloid.
First Insights into the Draft Genome Sequence of the Endophyte Paenibacillus amylolyticus Strain GM1FR, Isolated from Festuca rubra L.
ABSTRACT Paenibacillus amylolyticus strain GM1FR is an endophyte isolated from aerial plant tissues of Festuca rubra L. Here, we report the draft genome sequence (7.3 Mb) of GM1FR containing 6,241 protein-coding genes, some of which are potentially involved in plant growth promotion and biocontrol.