Structure of thalicmidine
The alkaloid thalicmidine isolated from the roots of Thalictrum minus by S. Yu. Yunusov and N. N. Pmgressov [1] contains three methoxy groups and one hydroxy group (broad band in the IR spectrum at 3200-3500 cm-~). The UV spectrum of thalicmidine has three maxima at 220, 280, and 305 mg (tog e 4.52, 4.12, 4.12), which are characteristic for 2, 3, 5, 6-tetrasubstituted aporphins [2]. Methylation of thalicmidine has given glaucine (Ia) and oxidation has yielded m-hemipinic acid, Consequently, the hydroxy group must occupy position 5 or 6 [3, 4]. Since thalicmidine is not identical with glaueentrine, only position 6 remains possible for the hydroxy group (Ib).
Flavonoids ofCentaurea depressa
The dried eomminuted bark (1.5 kg) from branches of 1 to 5 years' growth was exhaustively extracted with 70% ethanol. The ethanolie extract was concentrated in vacuum, diluted with water and treated first with chloroform and then with ethyI acetate. The ethyl acetate extract was evaporated to small bulk, and the flavonoids were precipitated by means of dry chloroform. The deposit that separated was dissolved in the minimum amount of 50% ethanol, and diethyl ether was added to saturation. The mixture was left in the refrigerator at 3-4" C. After 10-12 days, 5, 7, 4'-trihydroxyflavone 5-B-D-glucopyranoside (salipurposide) [4], C21Hz2010 • t . 5 H20, with mp 226-227° C (water), Xma x 328, 282mp crystallized outl melting point of the acetyl derivative 182-183° C (96% ethanol).
The chemicial consitituents of Australian Zanthoxylum species. II. The Constituents of Z. brachyacanthum F. Muell., Z. veneficum F.M. Bail., and Z. suberosum C.T. White
The known substances l-α-canadine methiodide, β-homochelidonine, chelerythrine, isocorydine methiodide (a new alkaloid), lupeol, and hesperidin have been isolated from both Z. brachyacanthum F. Muell. and Z. veneficum F. M. Bail. and it is suggested that these two species are identical. From Z. suberosum C.T. White the recently discovered alkaloid, canthin-6-one, was isolated.