A gamma-ray imager for arms control
Ascertaining the number of warheads on a missile-delivery systems by a remote, nonvisual inspection may be desirable in some arms-control verification scenarios. A gamma-ray imaging system (GRIS) has been developed to inspect for nuclear warheads by imaging the highly penetrating gamma-radiation emitted by radioactive materials integral to warheads. Such an image may be used to obtain the missile loadout. The authors describe the GRIS's operating principles and capabilities, present data, and discuss the advantages and disadvantages of such a system for arms control. They also present field results where GRIS was used on an emplaced Peacekeeper missile. Improvements to GRIS in light of the field trial results are presented.<<ETX>>
Measurements with Pinhole and Coded Aperture Gamma-Ray Imaging Systems
From a safeguards perspective, gamma-ray imaging has the potential to reduce manpower and cost for effectively locating and monitoring special nuclear material. The purpose of this project was to investigate the performance of pinhole and coded aperture gamma-ray imaging systems at Oak Ridge National Laboratory (ORNL). With the aid of the European Commission Joint Research Centre (JRC), radiometric data will be combined with scans from a three-dimensional design information verification (3D-DIV) system. Measurements were performed at the ORNL Safeguards Laboratory using sources that model holdup in radiological facilities. They showed that for situations with moderate amounts of solid or dense U sources, the coded aperture was able to predict source location and geometry within ~7% of actual values while the pinhole gave a broad representation of source distributions
Engineering bio-inks for 3D bioprinting cell mechanical microenvironment
Three-dimensional (3D) bioprinting has become a promising approach to construct­ing functional biomimetic tissues for tissue engineering and regenerative medicine. In 3D bioprinting, bio-inks are essential for the construction of cell microenviron­ment, thus affecting the biomimetic design and regenerative efficiency. Mechanical properties are one of the essential aspects of microenvironment, which can be char­acterized by matrix stiffness, viscoelasticity, topography, and dynamic mechanical stimulation. With the recent advances in functional biomaterials, various engineered bio-inks have realized the possibility of engineering cell mechanical microenviron­ment in vivo. In this review, we summarize the critical mechanical cues of cell micro­environments, review the engineered bio-inks while focusing on the selection princi­ples for constructing cell mechanical microenvironments, and discuss the challenges facing this field and the possible solutions for them.