A high sensitivity chemiluminescence-based CMOS image biosensor for the detection of human interleukin 5 (IL-5)
In this study, a CMOS image sensor that converts light intensity to digital image data was used to detect human interleukin 5 (IL-5). Although the application of CMOS image sensors to biosensors is well known, a more sensitive method is needed to detect molecules with very low concentrations such as cytokines. For this reason, we have used a chemiluminescence reaction to increase the sensitivity of sandwich immunoassay in CMOS image sensor. Another approach used to obtain a high sensitivity response was the pixel counting analysis. By using pixel counting analysis, much more detailed luminescence signals can be obtained. The detection sensitivity of IL-5 we obtained in our experimental measurements was evaluated up to 0.1 pg/mL.
Integrated biosensors in CMOS
This paper reviews several integrated biosensing technologies compatible with standard CMOS process. With a particular focus on detecting biomolecules and molecular interactions, the selected sensing modalities include electrochemical biosensor, fluorescent biosensor, magnetic biosensor, and gravimetric biosensor. For each modality, the sensing mechanism is first presented, and is then followed by a typical design example. Advantages as well as limitations of the sensing technology are also discussed.
Research on automatic tracking solar power system
The paper elaborates the features of solar power. On the foundation of it, it analyses the composing, the theory and the features of solar power system of automatic tracking, analyzing the function of mental composing and the important technology, making a compartment of the amount of generation of solar power system of automatic tracking and that of common solar power system.