2,3,7-Trimethcxy-8,9-methylenedioxypavinan — A new alkaloid from Thalictrum strictum. II
F rom the epigeal pa r t of Th. s t r i c tum we have i so la ted a new unidentified base B (I). The alkaloid (I) is readi ly soluble in methanol , ethanol, and acetone and when the solvents are evapora ted it s epa ra t e s out in the fo rm of a faint yellowish oil . After chromatography twice on a column of a lumina and concentrat ion of the e therea l eluate, compound (I) c rys ta l l i zed in the fo rm of t r anspa ren t p r i s m s with mp 144-145°C, [o~]~ 1 7 4 ° (c 0.977; methanol).
THE ALKALOIDS OF PAPAVERACEOUS PLANTS: LIV. THE STRUCTURE OF ESCHSCHOLTZINE
Eschscholtzine, a new alkaloid from Eschscholtzia californica, has been shown to be the bismethylenedioxy analogue of N-methylpavine (argemonine). The mass spectrometric fragmentation of alkaloids of the pavine type is discussed.
Optical rotatory dispersion and absolute configuration—III
Abstract Optical rotatory dispersion measurements on pyrrolidine, piperidine, and tetrahydro-isoquinoline alkaloids indicate that the absolute configuration of the α-asymmetric center may be assigned directly from the dispersion curve, provided either that the nitrogen atom is not protonated, or that the compound contains a chromophore absorbing above 200 mμ.