Electrical anomalies on spacecraft due to hypervelocity impacts
One of the main challenges in satellite design is dealing with the threat from the space environment. Numerous spacecraft anomalies are reported on a regular basis and in most of these cases, it is extremely difficult to diagnose the cause of these anomalies/failures. Hypervelocity impacts from meteoroids and orbital debris has recently emerged as possible catalysts for electrical anomalies observed on spacecraft. In this paper, we present a case study and statistical analysis of hypervelocity impact-induced electrical anomalies. We present data showing anomalous currents in the power distribution system on the JASON-1 satellite following a hypervelocity impact. A statistical analysis is carried out using 2413 anomalies from the Ascend satellite anomaly database and 5033 anomalies from the anomaly database maintained in the 1990s by the National Geophysical Data Center (NGDC). We find that there is no correlation between the flux of shower meteoroids and incidence of anomalies. For geostationary satellites, we use NASA's Meteoroid Engineering Model to calculate the flux of sporadic meteoroids at different locations in the orbit and find that the incidence rate of anomalies is significantly higher in regions with high average meteoroid flux. These results serve as a strong indicator of electrical damage caused by electromagnetic emissions from meteoroid impacts.
Interference on Logic Chips due to Plasma Created by Hypervelocity Impact on 2024-T4 Aluminum Target
To acquire the interference status of typical logic chips in spacecraft caused by plasma generated from a hypervelocity impact,the triple Langmuir probe system established by selfishness is used for diagnostics of plasma characteristic parameters created by 2024-T4 aluminum projectile hypervelocity impact on 2024-T4 aluminum target,with the impact velocity and incidence angle of 6.10 km/s and 30°,respectively.The plasma electron density is measured at a given position with a given azimuth,and the interference estimation is performed for logic chip by data acquisition system.The experimental results show that the logic chips in spacecraft will be seriously influenced by plasma generated at hypervelocity impact.
Botulinum toxin in the management of chronic migraine: clinical evidence and experience
Chronic migraine (CM) is a severely disabling neurological condition characterized by episodes of pulsating unilateral or bilateral headache. The United States Food and Drug Administration (FDA) approved onabotulinumtoxinA (Botox®) for the prophylactic treatment of CM in 2010. It has been shown that onabotulinumtoxinA is effective in the reduction of headache frequency and severity in patients with CM. Treatment is well tolerated by the patients. This review reports on the history of botulinum neurotoxin (BoNT) in CM and presents the current clinical evidence for the use of onabotulinumtoxinA in the treatment of CM.