Parametric geometry modeling of the carotid artery bifurcation: the need for new flow metrics
Although well established correlations now exist between regions of reversed flow and sites of arterial disease [1], little evidence is available for methodologies that systematically compare how geometrical differences affect such relationships. Drawing on techniques developed in aerodynamic design, a parametric tuning-fork geometry model of the carotid artery bifurcation - based on the glass models described in [2] - is here employed to investigate the impact of bulb size and the angle of the internal carotid artery (ICA) on time-averaged shear stress. Since we seek to directly compare the effect of varying these geometric parameters, we demonstrate the need for a new metric, the integral of negative mean shear stress (INMSS), to highlight the stronger correlation between the extent of reversed flow and bulb width relative to the angle of the ICA.
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Antimicrobial activity in pulp extract of Neem(Azadirachta indica Linn.)
Antimicrobialactivityin leaf extract of neem ( Azadirachta indica ) against human pathogenic bacteria. E.coli, Staphylococcus aureus, Pseudomonas aeruginosa , Salmonella typhimurium, Bacillus pumilus. Antimicrobia l activities of alcoholic extracts of neem leaves were used. Varying concent ration of each extracts 200mg/ml, 150 mg/ ml,100mg/ml, 50mg/ml, 25mg/ml prepared by using disc diffusion method. When compared with gentamycin 200mg and gentamycin 10mg, the methanol and ethanol extract shows maximum inhibition on Bacillus pumillus, Pseudomonas aeruginosa and Staphylococcus aureusin an asending order.