Reliability Analysis of Safety Grade Programmable Logic Controller
This paper focuses on the random hardware failures necessary for the safety assessment of the reactor protection system (RPS). A prediction method of the hardware failure rate for safety assessment is suggested, and applied to the safety grade programmable logic controller (PLC) to identify design weak points from a safety point of view
A Middleware Layer Monitoring Structure for the Real-time Middleware
This paper proposes MMS (TMO model-based middleware monitoring structure), a structure for monitoring the middleware. MMS can be an infrastructure to check the performance and stability of the middleware, and to guarantee the reliable operation of the TMO applications by managing the operational status of the middleware threads. Moreover, this paper implements a middleware monitor as a supporting tool for developers to monitor the MMS-instrumented middleware. Thus, developer can manage the real-time system more stably, using the MMS-instrumented middleware and the middleware monitor proposed in this paper
Rotating dialysis cell as in vitro release method for oily parenteral depot solutions.
The purpose of the study was to investigate an in vitro release method based on a rotating dialysis cell for parenteral oil depot formulations using different model conditions and test formulations. The total amount of drug released from the rotating dialysis cell was in accordance with the theoretical values calculated from the partition coefficients. The release rates were shown to depend on the total amount of drug available for the release process and to follow first order kinetics. The rotating dialysis cell has a potential as in vitro release method for characterization of oily depot formulations for parenteral administration.