Is 2,3,4,5-tetramethoxybenzoyl chloride a natural product?
The title compound, which was reported to be a constituent of the fruiting body of the fungus Antrodia camphorata, has been synthesized. The reactivity and spectroscopic properties of the synthetic material do not match those of the natural product. There is currently insufficient information for a definitive structural reassignment.
Ethynylbenzenoid metabolites of Antrodia camphorata: synthesis and inhibition of TNF expression.
An improved synthesis of the anti-inflammatory natural product antrocamphin A (2), involving a key Castro-Stephens reaction, is presented, along with the first total synthesis of its congener antrocamphin B (3). Approaches towards the more complex co-metabolite antrodioxolanone (4) were unsuccessful, but a samarium diiodide-mediated pinacol coupling of antrocamphin B did provide the chiral epimers (51). Antrocamphin A (2) inhibits Tumour Necrosis Factor (TNF) reporter gene expression, but its development as an anti-inflammatory agent may be limited by cytotoxicity.
APPLICATION OF SATELLITE PHOTOGRAPHS IN A MORPHOTECTONIC STUDY OF THE CENTRAL ALBORZ, IRAN
This paper introduces a study of morphotectoni c structure in the Central Alborz Basin, Mazandaran province of Iran (about 1200 square kilometer), using Russian KFA-1000 satellite photography and sequential air photographs. The KFA-1000 metric camera has better ground resolution than SPOT and LANDSAT for the whole of the study area. Results are provided from one pair of 30×30 cm. photos, which provided easy interpretation and better results than other data. Areas identified from these images as being of significance were examined in greater detail through the use of aerial photographs (at scales of 1:5000, 1:10000 and 1:60000 were available).