Source of the detrital components of uraniferous conglomerates, Quirke ore zone, Elliot Lake, Ontario, Canada
Large volumes of pyritic quartz-pebble conglomerate in the Elliot Lake district of Ontario contain at least 300,000 tonnes U3O8 recoverable at a grade of 0.1% (ref. 1), with much greater tonnages available at lower recovery grades. The Quirke zone alone contains in excess of 224,000 tonnes U3O8 at ∼0.1% (refs 2–4) and is, accordingly, one of the world's largest known uranium deposits. Situated 40 km north of the North Channel of Lake Huron, 400 km north-west of Toronto, ore conglomerates occur in the Matinenda Formation, locally the basal unit of the Huronian Supergroup, and, although their age is not well constrained, they are probably close to 2,350 Myr old.5 Uraninite, the most important primary ore mineral, occurs as poorly rounded to euhedral grains 0.05–0.2 mm across within the matrix between quartz pebbles. While its chemical and morphological characteristics have led most workers to consider that the uraninite is detrital5–7, there has hitherto been no attempt to characterize its source lithology, a matter of considerable significance as regards mineral exploration. This was the aim of the present study. We have examined the mineral and fluid inclusions observed in the quartz pebbles in the conglomerate and conclude that they were derived from a pegmatitic, potassic (alaskitic) granite. We have also demonstrated that in this source lithology, pebble-sized quartz was spatially associated with radioactive minerals, by inference, uraninite. The postulated characteristics of such a source are remarkably similar in several respects to the uraniferous alaskites of the Rössing deposit in Namibia.
History of Arsenic as a Poison and a Medicinal Agent
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Molecular diversity of skin mucus lectins in fish.
Among lectins in the skin mucus of fish, primary structures of four different types of lectin have been determined. Congerin from the conger eel Conger myriaster and AJL-1 from the Japanese eel Anguilla japonica were identified as galectin, characterized by its specific binding to beta-galactoside. Eel has additionally a unique lectin, AJL-2, which has a highly conserved sequence of C-type lectins but displays Ca(2+)-independent activity. This is rational because the lectin exerts its function on the cutaneous surface, which is exposed to a Ca(2+) scarce environment when the eel is in fresh water. The third type lectin is pufflectin, a mannose specific lectin in the skin mucus of pufferfish Takifugu rubripes. This lectin showed no sequence similarity with any known animal lectins but, surprisingly, shares sequence homology with mannose-binding lectins of monocotyledonous plants. The fourth lectin was found in the ponyfish Leiognathus nuchalis and exhibits homology with rhamnose-binding lectins known in eggs of some fish species. These lectins, except ponyfish lectin, showed agglutination of certain bacteria. In addition, pufflectin was found to bind to a parasitic trematode, Heterobothrium okamotoi. Taken together, these results demonstrate that skin mucus lectins in fish have wide molecular diversity.