Olivomycin and related antibiotics XXVIII. Monomeric composition of aureolic acid and proof that the antibiotics LA-7017 and mithramycin are identical to it
Summary1. It has been shown that aureolic acid, antibiotic LA-7017, and mithramycin are identical.2. It has been established that aureolic acid is a glycoside of chromomycinone (I) and contains the monosaccharides D-olivose (II), D-oliose (III), and D-mycarose (IV) in a ratio of 3 : 1 : 1.
The reactions of chromomycinone and derivatives
Abstract The various reactions of chromomycinone, the chromophore of the cancerostatic chromomycins, are described. The structures of several chromomycinone derivatives are also discussed.
Stereochemistry of grayanotoxins
Abstract The stereochemistry of the grayanotoxins is discussed on the basis of chemical and physicochemical data, and the stereostructures XLI, XLII and XLIII have been assigned to grayanotoxin-I, -II and -III, respectively.