Disturbance Observer-Based Predictive Functional Critical Control of a Table Drive System
This paper addresses a control system design for a table drive system based on the disturbance observer (DOB)-based predictive functional critical control (PFCC). To empower the previously developed DOB-based PFC to handle constraints on controlled outputs, we propose to take a critical control approach. To this end, we derive the transfer function representation of the PFC controller and yield a detailed design procedure. The effectiveness of the proposed method is confirmed through an experimental evaluation.
An improved state-space model structure and a corresponding predictive functional control design with improved control performance
Conventional state-space model predictive control requires a state estimator/observer to access the state information for feedback controller design. Its drawbacks are the numerical convergence stability of the observer and closed-loop control performance deterioration with activated plant input/output constraints. The recent direct use of measured input and output variables to formulate a non-minimal state-space (NMSS) model overcomes these problems, but the subsequent controller is too sensitive to model mismatch. In this article, an improved structure of NMSS model that incorporates the output-tracking error is first formulated and then a subsequent predictive functional control design is proposed. The proposed controller is tested on both model match and model mismatch cases for comparison with previous controllers. Results show that control performance is improved. In addition, a linear programming method for constraints dealing and a closed form of transfer function representation of the control system are provided for further insight into the proposed method.
Nuclear sphingolipid metabolism.
Nuclear lipid metabolism is implicated in various processes, including transcription, splicing, and DNA repair. Sphingolipids play roles in numerous cellular functions, and an emerging body of literature has identified roles for these lipid mediators in distinct nuclear processes. Different sphingolipid species are localized in various subnuclear domains, including chromatin, the nuclear matrix, and the nuclear envelope, where sphingolipids exert specific regulatory and structural functions. Sphingomyelin, the most abundant nuclear sphingolipid, plays both structural and regulatory roles in chromatin assembly and dynamics in addition to being an integral component of the nuclear matrix. Sphingosine-1-phosphate modulates histone acetylation, sphingosine is a ligand for steroidogenic factor 1, and nuclear accumulation of ceramide has been implicated in apoptosis. Finally, nuclear membrane-associated ganglioside GM1 plays a pivotal role in Ca(2+) homeostasis. This review highlights research on the factors that control nuclear sphingolipid metabolism and summarizes the roles of these lipids in various nuclear processes.