Passive negative feedback in mode-locked solid-state lasers.
Passive negative feedback by an intracavity GaAs platelet in actively/passively mode-locked solid-state lasers is reexamined, and the role of both single- and two-photon absorption in determining the features of the pulses and the pulse train is explored and compared with the experimental results. The time–bandwidth product is shown to acquire in the steady-state part of the train a value close to the minimum allowed by the uncertainty relation.
CW passive mode-locking evolved from Q-switched mode-locking in erbium doped fiber lasers
Summary form only given. We report a new mode-locking mechanism, where the use of a two-photon absorber in addition to a saturable absorber allows for CW mode-locking to reliably evolve from Q-switched mode locking. An optimal design of the two-photon absorber limits the peak power of the Q-switched pulses via optical limiting and thus aids in preventing damage to the saturable absorber. Moreover, the threshold for optical limiting is chosen to set an optimum stability point for CW mode-locked operation.
Hapten inhibition of passive antidextran dextran anaphylaxis in guinea pigs. Role of molecular size in anaphylactogenicity and precipitability of dextran fractions.
High titred antidextran antisera have been raised in rabbits by prolonged immunization with soluble conjugates between isomaltose oligosaccharides or dextran mw 4,400 and bovine serum albumin in complete Freund’s adjuvant. Guinea pigs sensitized with such antisera exhibited anaphylactic shock on i.v. challenge with fractions of hydrolyzed B512 dextran. The severity of anaphylaxis depended on the amount of sensitizing antibody and the dose and molecular size of the challenging dextran fraction. In maximally sensitized animals, fractions of mw 3,600 or larger were anaphylactogenic and smaller molecular size fractions were nonanaphylactogenic. In submaximally sensitized animals, dextran fractions of mw 10,500 or less were foundnonanaphylactogenic. In addition, nonanaphylactogenic dextran fractions produced desensitization, i.e. protection from anaphylaxis due to subsequent or simultaneous injection of more high molecular and anaphylactogenic dextran fractions. When the molar ratio in a mixture of nonanaphylactogenic/anaphylactogenic fractions was about 7.6, protection was complete with reduction of mortality from 100 to 0%. A molar ratio of 1.9, corresponding to a 13-percent by weight admixture of nonanaphylactogenic dextran, still significantly reduced mortality from 100 to 50%. From the ability to form precipitates with antidextrans and to elicit anaphylaxis in sensitized guinea pigs, and from the absence of these properties, the approximate molecular size range of bivalent and monovalent dextran B512 fractions was found to correspond to mw 3,600 and mw 1,430, respectively. The practical applicability of hapten inhibition is discussed.