γ-Pyrone derivatives fromHalenia corniculata
From 500 g of the epigeal part of Halenia corniculata (L.) Cornaz., collected in the Pribaikal region of the Buryat ASSR in July 1975, by extraction with 70% ethanol followed by treatment with chloroform we have isolated 32.7 g of extractive substances. Chromatography of the chloroform extract on silica gel with elution by chloroform yielded substances (i) and (2) of xanthone nature, and chloroform-ethanol (9:1) yielded luteolin, which was identified by its UV, mass, and PMR spectra and by comparison with an authentic sample [i].
Iridoids and Flavonoids of Four Siberian Gentians: Chemical Profile and Gastric Stimulatory Effect
Some Gentiana species have been used by the nomadic people of Siberia as bitter teas or appetizers to eliminate digestive disorders (dyspepsia, heartburn, nausea, etc.). We studied the most frequently used gentians: Gentiana algida, G. decumbens, G. macrophylla and G. triflora. The aim of the present study was to evaluate the phytochemical features and gastrostimulatnt activity of these four gentian herbs. Five iridoids, seven flavones and mangiferin were detected in gentian herbs after analysis by microcolumn-RP-HPLC-UV-ESI-MS. A componential phytochemical profile of the G. decumbens herb is presented for the first time, as well as information about distinct phytochemicals found in gentian herbs. HPLC quantification of the specific compounds of gentian herbs demonstrated the high content of iridoids (24.73–73.53 mg/g) and flavonoids (12.92–78.14 mg/g). The results of biological activity evaluation of four gentian decoctions demonstrated their good ability to stimulate acid-, enzyme- and mucin-forming functions of the stomach attributed to mostly by iridoids and flavonoids. In general, it can be claimed that the gentian decoctions can be used as effective and safe appetizers and are also a good source of biologically active agents.
The xanthones of macrocarpaea glabra
Abstract Extracts of both roots and stem of Macrocarpaea glabra (L.f.) Gilg (Gentianaceae) have been shown to yield 1-hydroxy-3,7-dimethoxyxanthone (I) and 8-hydroxy-1,2,6-trimethoxyxanthone (IIb).