Remarkable effect of nitrogen dioxide for N-hydroxyphthalimide-catalyzed aerobic oxidation of methylquinolines.
Aerobic oxidation of methylquinolines was successfully achieved by the use of N-hydroxyphthalimide/Co(OAc)2/Mn(OAc)2 as catalyst in the presence of a small amount of nitrogen dioxide as an initiator.
Oxidation of Methylquinolines with Nickel Peroxide
Abstract Room temperature oxidation of 2-(or 3-)methylquinoline-3-(or 2-)carboxylic acid with 3.25 eq nickel peroxide in aqueous base gives quinoline-2,3-dicarboxylic acid in high yield. No reaction occurs for methylpyridinecarboxylic acids under these conditions.
Nickel-peroxide oxidation of organic compounds
In dem Ubersichtsreferat werden Nickelperoxid-Oxidationen u.a. von Alkoholen, Phenolen, Polyhydroxyverbindungen, Carbonylverbindungen, Substanzen mit aktiven CH-Gruppen, Heterocyclen, Hydrazonen, Hydroxylaminen und Oximen behandelt.