STRUCTURE AND BIOLOGICAL ACTIVITY OF LIPIARMYCIN
Actinoplanes deccanensis ATCC21983, the producer of antibiotics lipiarmycin A3 and A4, furnished also a related antibiotic designated lipiarmycin B, active against Gram-positive bacteria, including anaerobes, and against Neisseria. The structures of the two major components, B3 and B4, were elucidated from their physico-chemical properties, XHand 13C NMRspectra and fast atom bombardmentmass spectra data in comparison with lipiarmycins A3andA4.
Lipiarmycin, a new antibiotic from Actinoplanes. I. Description of the producer strain and fermentation studies.
The producer strain of the new antibiotic, lipiarmycin, is described. The colony morphology, the presence of globose sporangia bearing motile spores, the absence of aerial mycelium and the presence of meso-DAP in cell wall, ascribe this strain to the genus Actinoplanes. The pigmentation and morphological characteristics together with the cultural and physiological features distinguish this strain from all the described Actinoplanes species. It is considered to be a new species for which the name Actinoplanes deccanensis nov. sp. is proposed. Lipiarmycin is produced in an organic complex medium containing NaCl. Production occurs at the end of trophophase and continues, though at decreasing rate, during isophase.
A wireless self-powered urinary incontinence sensor system
A self-powered urinary incontinence sensor system consisting of a disposable urine-activated coin battery and a wireless transmitter has been developed as an application for wireless sensor networks. The urine-activated battery makes possible both the sensing of urine leakage and self-powered operation. An intermittent power-supply circuit that uses an electrical double-layer capacitor (EDLC) with a small internal resistance suppresses the supply voltage drop due to the large internal resistance of the battery. This circuit and a 1-V SAW oscillator reduce the power dissipation of a wireless transmitter. The SAW oscillator quickly responds to the on-off control of the power supply, which makes it suitable for intermittent operation. To verify the effectiveness of the circuit scheme, we fabricated a prototype sensor system. When the volume of urine is 0.2 ml, the battery outputs a voltage of over 1.3 V; and the sensor system can transmit signals over a distance of 50 cm.