The Conflict of Nationalisms in South Africa
Can the paths of African nationalism be shaped by white communities? And, if so, in what direction might African nationalism be led? These are questions which puzzle white governments in all parts of Africa. Though African nationalism may be recognized as having its own inner dynamics, and to be an inevitable growth, no matter how hostile the Western powers and white settlers may be to it, yet tJiere is an assumption underlying the policies of most governments in Africa that the particular paths which African nationalism will follow can be shaped by the kinds of alternatives which the white communities offer to it.
South Africa and the International Community
Ever since the discovery there of gold and diamonds in the last half of the nineteenth century, South Africa has engaged the rapt attention of the Western world. The saga of the Anglo-Boer War of 1899–1902, perhaps the last of the “gentlemen's wars,” and now the refurbished accounts of the gallant defense of Rorke's Drift in the AngloZulu War of 1879 have been fascinating material for both novelists and film scriptwriters. In addition, the history of South Africa is replete with titanic figures who rank with, or perhaps even above, those from the rest of the continent: the aggressive architect of empire, Cecil J. Rhodes; the redoubtable Zulu warrior, Chaka; the dour, stern-willed President of the South African Republic, “Oom” (Uncle) Paul Kruger; the world-renowned statesman and philosopher, Field Marshal Jan C. Smuts; the founding father of Indian independence, Mohandas K. Gandhi; the compassionate and courageous writer, Alan S. Paton; and the dignified, modest Zulu Nobel Laureate, Albert J. Luthuli. By any standard, South Africa and its leaders of all races have made far-reaching and impressive contributions to the continent, the British Empire, and the world at large.
Mucoadhesive Nanoparticles for Drug Delivery to the Anterior Eye
While the use of topical drops for the delivery of drugs to the anterior of the eye is well accepted, it is far from efficient with as little as 5% of the drug instilled on the eye actually reaching the target tissue. The ability to prolong the residence time on the eye is desirable. Based on the acceptability of 2-hydroxyethyl methacrylate based polymers in contact lens applications, the current work focuses on the development of a poly(2-hydroxyethyl methacrylate (HEMA)) nanoparticle system. The particles were modified to allow for degradation and to permit mucoadhesion. Size and morphological analysis of the final polymer products showed that nano-sized, spherical particles were produced. FTIR spectra demonstrated that the nanoparticles comprised poly(HEMA) and that 3-(acrylamido)phenylboronic acid (3AAPBA), as a mucoadhesive, was successfully incorporated. Degradation of nanoparticles containing N,N′-bis(acryloyl)cystamine (BAC) after incubation with DL-dithiothreitol (DTT) was confirmed by a decrease in turbidity and through transmission electron microscopy (TEM). Nanoparticle mucoadhesion was shown through an in-vitro zeta potential analysis.