EFFECT OF MERTHIOLATE (LILLY) ON CERTAIN SPECIFIC PRECIPITATION REACTIONS.
Merthiolate (Lilly), a substituted benzoic acid, has been shown to interfere, in concentrations usually used for preservation, with the specific precipitation of antisera against beef serum or sheep serum coupled with diazotized p-aminobenzoic acid, p-arsanilic acid, or p-(p-aminophenylazo) phenylarsonic acid. In some systems increased precipitation was observed, while in others decreased precipitation was observed.
The Serological Properties of Simple Substances. I. Precipitation Reactions between Antibodies and Substances Containing Two or More Haptenic Groups
The problem of obtaining from precipitation experiments evidence about the structure of antibodies and the nature of serological reactions is obviously greatly simplified by the replacement of protein antigens by simple substances of known structure. For this reason we began and are carrying on an extensive program of investigation of the reactions of simple substances with antisera. In this paper we report the quantitative study of the precipitin reaction for twenty simple substances containing two or more haptenic groups, and the results of tests of seven substances containing one group. It is found that the observations support the framework theory of serological precipitates.
Developmental aphasia: The perception of brief vowels and extended stop consonants
Abstract Developmental dysphasics and matched controls were examined for their ability to discriminate (a) two synthesized vowel-vowel syllables and (b) two synthesized consonant- vowel syllables. For both vowels and consonants, dysphasics were impaired when the discriminable components of the two stimuli were brief (43 msec) but unimpaired when these components were 95 msec or longer. It is concluded that developmental dysphasics have no difficulty in discriminating transitional auditory information as such and that their impaired discrimination of synthesized stop consonants is attributable solely to the brief duration of the discriminable components.