Enflurane (Ethrane, compound 347) in man *
Enflurane (2 chloro-1, 1,2-trifluoroethyl difluoro methyl ether) (CHFrOCFrCHFC1) is a halogenated liquid developed by Ross Terrell with the trade name Ethrane1’2. Enflurane has a pleasant, non-irritating smell, is volatile, colourless, non-flammable, stable with soda-lime, and unaffected by metals, light, moisture, heat and oxygen. It is non-explosive in anaesthetic concentrations when mixed with oxygen, air or nitrous oxide. Table 1 shows its physical and chemical characteristics. Virtue et al. 3 confirmed the anaesthetic properties of enflurane in dogs. They found that the agent was incompatible with the use of adrenaline and discovered some evidence of neuromuscular excitation under deep anaesthesia. McDowell and his colleagues4 also used enflurane on dogs. They produced some cardiac and respiratory depression and reported that it
Estimation of the level of anesthesia during surgery by automatic EEG pattern recognition
The f e a s i b i l i t y of developing an automatic electroencephalographic (EEG) pattern recognition system for reliably estimating the level of con-
Glycogen phosphorylase in lobster hepatopancreas: action of proteases on the enzyme
Abstract 1. 1. In lobster hepatopancreas, extracellular protreases cause the inactivation of glycogen phosphorylase. 2. 2. The proteolysis of glycogen phosphorylase purified from rabbit muscle by these proteases has been shown by SDS-polyacrylamide gel electrophoresis. 3. 3. A cell isolation technique has allowed us to remove proteases of extracellular digestion and to measure glycogen phosphorylase activity in lobster hepatopancreas. 4. 4. The glycogen phosphorylase activity seems to be mainly associated with R cells while it could not be detected in B cells.