Is 2,3,4,5-tetramethoxybenzoyl chloride a natural product?
The title compound, which was reported to be a constituent of the fruiting body of the fungus Antrodia camphorata, has been synthesized. The reactivity and spectroscopic properties of the synthetic material do not match those of the natural product. There is currently insufficient information for a definitive structural reassignment.
Anti-inflammatory benzenoids from Antrodia camphorata.
Four new compounds, including three new benzenoids, antrocamphin A (1), antrocamphin B (2), and 2,3,4,5-tetramethoxybenzoyl chloride (3), and a new 1,3-dioxolan-2-one derivative, antrodioxolanone (4), together with 13 known compounds have been isolated from the fruiting body of Antrodia camphorata. The structures of these new compounds were determined through spectral analyses including extensive 2D-NMR data. Among the isolates, antrocamphin A (1), antcin A (10), and antcin B (11) exhibited potent inhibition against fMLP-induced superoxide production with IC50 values less than 10 microM.
Chemical constituents and chemotaxonomic study of Glycyrrhiza pallidiflora maxim
Abstract Phytochemical study of Glycyrrhiza pallidiflora Maxim. gave seventeen compounds, including two sterols (3 and 4), four triterpenes (1, 2, 5, 6), ten flavones (7, 9–17), and one pterocarpan (8). The chemotaxonomic significance of G. pallidiflora was discussed, which indicated the close relationship between G. pallidiflora with other species of Glycyrrhiza. Moreover, pallidiflorin can be served as a fingerprint for G. pallidiflora, macedonic acid and echinatin can be recognized as biomarkers for Glycyrrhiza, while formononetin, afrormosin and calycosin may be typical second metabolites for Papilionoideae.