Reactions of mental chelates. I. The reactions of copper (II) chelates of some beta-diketones and their related compounds with glycine, diglycine and triglycine.
The reactions of copper(II) chelates of β-diketones such as acetylacetone, benzoylacetone, dibenzoylmethane and benzoylacetaldehyde and of chelates of their related compounds such as salicylaldehyde and 2-hydroxyacetophenone with glycine or glycylglycine were investigated. Only bis(salicylaldehydato)copper(II) and bis(benzoylacetaldehydato)copper(II) reacted with glycine to form the respective glycinato-Schiff base complexes, whereas the other chelates did not react with glycine under the same condition. On the other hand, all the chelates except bis(dibenzoylmethanato)copper(II) reacted with glycylglycine to form the respective glycylglycinato-Schiff base complexes. The reaction at pH 4.5 between bis(salicylaldehydato)copper(II) and triglycine resulted in the hydrolytic cleavage of peptide bond, producing the salicylideneglycylglycinatocuprate(II) and free glycine. As the results of this investigation, five new copper(II) chelates were synthesized and characterized.
The Preparation and Properties of N-Salicylideneglycinato-aquo-copper(II), Sodium N-Salicylideneglycylglycinato-cuprate(II) and Related Compounds
The two new compounds, N-salicylideneglycinato-aquo-copper(II) and sodium N-salicylideneglycylglycinato - cuprate(II) were prepared and investigated as to their structure. Their infrared, visible and ultraviolet absorption spectra together with those of some related compounds were measured and discussed.
Physical Chemistry for the Life Sciences
PART 1 - BIOCHEMICAL THERMODYNAMICS PART 2- THE KINETICS OF LIFE PROCESSES PART 3 - BIOMOLECULAR STRUCTURE PART 4 - BIOMOLECULAR SPECTROSCOPY