A study of the alkaloids ofVeratrum lobelianum
Conclusions1) At the beginning of vegetation, the total alkaloids in the epigeal part ofVeratrum lobelianum is 2.5% of the weight of the dry raw material, and at the end of vegetation, 0.036%.2) The new alkaloids veralosine, veralosinine, and veralosidine have been isolated from the epigeal part of the plant.3) On the basis of a study of chemical properties, IR, UV, NMR, and mass spectra, and also its conversion into tetrahydrosolasodine, structure and configuration I has been proposed as the most probable for veralosidine.
Solanum-alkaloide—XLVI : Synthese von solasodin
Abstract The steroidal alkaloid solasodine [(25R)]-22αN-spirosol-5-en-3β-ol, XIII] which was isolated from more than 60 species of the genus Solanum (Solanaceae) has been synthesized from (22S:25R)-22,26-imino-5α-cholestane-3β,16β-diol[tetrahydrosolasodine A, I]. The described transformation formally represents the total synthesis of solasodine, since the starting I is available from a simple pregnane derivative.
über die Beckmann sche Umlagerung von 20‐Ketosteroidoximen
Die Beckmannsche Umlagerung von 20-Ketosteroidoximen verlaft bei Anwendung einer Mischung von Pyridin-Phosphoroxychlorid lauft bei Anwendung einer Mischung von Pyridin-Phosphoroxychloird praktisch quantitativ. Die erhaltenen 17-Acetylamine gehen durch energische alkalische Verseifung bei etwa 180° mit uber 90% Ausbeute in die freien 17-Amine uber, die am besten in Form ihrer schwer loslichen Salze isoliert werden.