The structure of regalamine
SummaryOn the basis of UV, IR, NMR, and mass spectra and chemical transformations the structure of 11,12-dihydroxy-2-methoxy-1,12-epoxyhexahydrohomoproaporphine has been proposed for regalamine.
Enantioselective Total Syntheses of Pentacyclic Homoproaporphine Alkaloids.
Herein we report the first enantioselective total syntheses of pentacyclic homoproaporphine alkaloids by means of a route, which includes a tandem retro-oxa-Michael addition and nucleophilic substitution to generate the oxa-benzobicyclco[3.3.1]nonane core structure, a Pictet-Spengler cyclization to construct the fused B and C rings, and sequential Baeyer-Villiger oxidation and pinacol-type cyclization to install the hydroxyl-lactol moiety of D ring. With this unified route, six pentacyclic homoproaporphine alkaloids have been synthesized enantioselectively.
Chemical Metallurgy: Principles and Practice
Foreword. Preface. Acknowledgements. Appreciation. 1. Acquaintance. 2. Mineral Processing. 3. Thermodynamics and Kinetics. 4. Pyrometallurgy. 5. Hydrometallurgy. 6. Electrometallurgy. 7. Energy and Environment. Subject Index.