Structure of thalicmidine
The alkaloid thalicmidine isolated from the roots of Thalictrum minus by S. Yu. Yunusov and N. N. Pmgressov [1] contains three methoxy groups and one hydroxy group (broad band in the IR spectrum at 3200-3500 cm-~). The UV spectrum of thalicmidine has three maxima at 220, 280, and 305 mg (tog e 4.52, 4.12, 4.12), which are characteristic for 2, 3, 5, 6-tetrasubstituted aporphins [2]. Methylation of thalicmidine has given glaucine (Ia) and oxidation has yielded m-hemipinic acid, Consequently, the hydroxy group must occupy position 5 or 6 [3, 4]. Since thalicmidine is not identical with glaueentrine, only position 6 remains possible for the hydroxy group (Ib).
A NEW QUATERNARY APORPHINE FROM FAGARA TINGUASSOIBA HOEHNE
An alkaloid isolated as picrate from Fagaratinguassoiba gives rise on methylation to a derivative of glaucine. It has been shown to be the 6-hydroxy-2,3,5-trimethoxy-N,N-dimethylaporphinium ion.
The Alkaloids ofCryptocarya angulataC.T. White andC. triplinervis
The bark of Cryptocarya triplinervis R.Br. yields the water-soluble alkaloid iso-corydine methiodide. The same compound has been obtained from the bark of C. angulata C.T. White, together with roemerine and 3,4-dimethoxy-1-dimethylamino-ethylphenanthrene. Although known in an impure state as a derivative of roemerine, the latter has not been isolated previously from natural sources.