From Mary Queen of Scots to the Scottish Capuchins: Scotland as a symbol of Protestant persecution in seventeenth-century Italian literature
Italian authors of the seventeenth century produced a myriad of historical texts, tragedies, oratorios and poems that dealt with the events of Mary Stuart's life. The tremendous outcry that her story caused all over Europe made Scotland one of the most powerful symbols of persecution of Catholics by Protestants. It was the image of Scotland as a land of martyrdom that possibly prompted the publication of two seventeenth-century Italian ‘biographies’, narrating the vicissitudes of the lives of two Scottish capuchins, and which ran to multiple editions down to the eighteenth century. This article explores the literary reception of Mary Queen of Scots in seventeenth-century Italian literature and, in so doing, opens up religious, cultural, and political implications, pointing to links between Scottish Catholic and European intellectuals, and the publishing networks of sympathetic Marian writing.
VII. The Earl of Essex on the Stage
The romantic career of that unhappy favorite of Queen Elizabeth, Robert Devereux, second Earl of Essex, like the histories of Mary Stuart and of the Maréchal de Biron, has been often used as a subject for tragedy in Spanish, French, Italian, German, and English. Several of these plays have been studied more or less carefully at different times, so that I shall not do more than summarize those versions briefly before passing on to my main subject, the relation between Niccolo Biancolelli's Regina Statista d'Inghilterra and its commedia dell'Arte variants, of which the one presented here is hitherto unpublished.
Modulation of neuronal serotonin uptake by a putative endogenous ligand of imipramine recognition sites.
Imipramine inhibits the serotonin uptake by binding with high affinity to regulatory sites of this uptake located on axons that release serotonin. The number of imipramine recognition sites located on crude synaptic membrane preparations is reduced by two daily injections of imipramine or desmethylimipramine for 3 weeks. When the binding sites for [3H]imipramine are down-regulated the Vmax of the neuronal uptake of serotonin is increased. Moreover, in minces prepared from the brain hippocampus of rats receiving imipramine in a dose regimen that reduces the number of [3H]imipramine recognition sites, the efficiency of imipramine as a blocker of the serotonin uptake is diminished. Hence the high-affinity binding sites for [3H]imipramine may have a physiological role in modulation of serotonin reuptake. Probably this is mediated by an endogenous effector of these regulatory sites. A nonpeptidic constituent of rat brain capable of displacing [3H]imipramine from its high-affinity binding site and of inhibiting the serotonin uptake in a dose-related manner has been extracted and its partial purification is described.