350-nm band edge-emitting laser diodes enabled by low-dislocation-density AlGaN templates
Realization of efficient laser diodes with ultra-violet (UV) emission from ~260-360 nm would enable many applications including fluorescence-based biological agent detection, sterilization, and portable water purification. While InGaN-based laser diodes are well developed down to ~370 nm, achieving shorter UV wavelengths requires higher Al-content AlGaN alloys with increasing challenges in achieving p-type doping, strain-management, and low threading-dislocation-density (TDD) AlGaN templates. Given these challenges, few groups have reported AlGaN-based edge-emitting laser diodes (LDs) with emission <; 355 nm.[1, 2] Most recently, random lasing via Anderson localization in AlGaN nanowire structures has demonstrated a novel approach to realizing deep-UV laser diodes.[3].
High‐performance UV emitter grown on high‐crystalline‐quality AlGaN underlying layer
Al0.25Ga0.75N films were grown on a grooved‐Al0.25Ga0.75N/ AlN/sapphire template by MOVPE. The dislocation density on the grooved areas was as low as 1 × 108 cm–2. We fabricated a UVA light‐emitting diode grown on such an AlGaN underlying layer exhibiting an output power of 12 mW at a DC current of 50 mA with a peak emission wavelength of 345 nm, which corresponds to an external quantum efficiency of 6.7%. This efficiency is the highest reported to date in this wavelength region. We also fabricated a 358 nm UVA laser diode (LD) using a GaN/AlGaN MQW active layer grown on an AlGaN underlying layer. This UV LD exhibits a threshold current of 73 mA and a corresponding current density of 3.8 kA/cm2 at 7 °C. The characteristic temperature T0 was 174 K in the temperature range of 7–27 °C. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Diversity of Electrospinning Approach for Vascular Implants: Multilayered Tubular Scaffolds
Abstract The biomimetics of biological structures found in nature remains one of the most promising approaches to engineer functional tissues from natural or synthetic biocompatible materials for the replacement of damaged or injured parts of the human body. Recently, medical therapeutic regimes have advanced into a new era, overcoming the known mechanical and biological variances that occur when using autologous or synthetic grafts. Basically, the core concept of tissue biofabrication, commonly referred to as tissue engineering, is to find out the favorable cellular microenvironments to grow a living tissue prior to clinical uses. In fact, the ability of stem cells to regenerate is controlled via signaling pathways (growth factors) and supporting materials (scaffolds) that guide the cellular activities. After the first successful experiments to fabricate polymer fibers from their solutions, Cooley proposed the use of an electric field a century ago (Cooley (US 692:631, 1902 ). The electrospinning technique has been continually developed as a fruitful polymer processing technique to draw ultrafine nonwoven fibers. Electrospun polymer fibers have been used for a wide range of technical and biotechnical applications such as filtration, organic solar cells, tissue engineering, and drug releasing implants. In this regard, this review begins with an overview about the various spinning approaches for the fabrication of polymer fibers as well as the basic principles of electrospinning process. In addition, this review will highlight vascular bypass surgery and, in particular, the needs for vascular tissue engineering. Finally, the review includes some of the latest attempts to improve the mechanical and biological properties of electrospun polymeric fibers and summarizes the challenges and prospects for the future. Lay Summary However, vascular defects are treated successfully via bypass surgical bypass grafting using autologous or synthetic vessels. The small-diameter vessels (less than 6) are often associated with high failure rate. This review reports some of the recent features that should be highlighted to fabricate an ideal graft for small-diameter vascular grafts. The review introduces multilayered conduits as an alternative approach to overcome the known mechanical and biological mismatches of single layered vascular grafts of electrospun polymers.