Etoricoxib selective sensor based on uracil-5,6-diamino-2-thio hydrochloride as neutral carrier for potentiometric analysis in pharmaceutical preparations
A construction and electrochemical behavior of novel potentiometric membrane sensor responsive to the etoricoxib was described. The sensor was based on the ion-pair complex of etoricoxib (ET) with Uracil-5,6-diamino-2-thio hydrochloride UDTH (ET-UDTH) as exchange sites in a PVC matrix with different plasticizers dibutylphthalate (DBP) (electrode B) tri-n-butylphosphate (TBP) (electrode C), and dioctylphthalate (DOP) (electrode A). The electrodes exhibited near-Nernstian response for ET-UDTH over the concentration range 0.051-40.042 mM. The electrode offered significant advantages including long lifetime (about 2 months), excellent stability and reproducibility, good response time (10-25 s), and wide pH working range (pH 5-12). Selectivity coefficients of ET related to a number of interfering cation and some organic compounds were investigated, and there were negligible interference caused by most of the investigated species. The direct determination of 0.5-10 mM of ET showed an average recovery of 99.03-101.75% and a mean relative standard deviation 0.40-1.88. The results were obtained by determination of ET in tablets using the proposed electrodes which were comparable favorably with those obtained by spectrophotometric method
PURE
Abstract Despite large public policy efforts over the past 30 years, a large minority of households remains consistently inadequately prepared for retirement. If policymakers want to address this shortcoming, public policy has to change from its current path. This paper suggests a system of mandatory private pensions funded by a minimum mandatory contribution of 3% of payroll. In addition, a number of institutional changes are suggested to reduce the costs and risks of individual accounts.
THE RELIGIOUS SITES DURING THE CHINESE CULTURAL REVOLUTION, 1966-1976
This study presents a thought-provoking picture of statistical data regarding the growth patterns of the religious sites for five main Chinese religions during the Cultural Revolution from 1966 to 1976. Applying comparative and quantitative lenses, this paper addresses the diE™erent growth rates of religious sites during the four diE™erent periods from 1949 to 2004 to test the relative growth pace of religious sites during the Cultural Revolution. To understand the patterns of growing religious sites from 1966 to 1976, this study also compares the diE™erent growth rates of religious sites between the first phase (1966 to 1970) and the second phase (1971-1976) of the Cultural Revolution. Furthermore, it provides detailed information concerning the year of building new religious sites for all five major religions that hold more than 2,500 new religious sites during the Cultural Revolution. In addition, the study shows the top five provinces which built the most new religious sites while denoting their respective rural and urban locations in an eE™ort to demonstrate their geographical expansion during the period. Finally, this study addresses the growth rates of the national population and per capita GDP as compared to the growth of the religious sites during the period of national disaster (1966-1976).