PHYTOCHEMICAL AND ANTIMICROBIAL STUDIES OF EXTRACTS OF SOLANUM XANTHOCARPUM
Antibacterial activity of various parts (stem, leaf and fruits) of solvent extracts (Petroleum ether, alcohol and acetone) of Solanum xanthocarpum against Escherichia coil, Klebsiella of Solanum xanthocarpum showed high sensitivity to Escherichia coil & less sensitivity and resistance to Bacillus cereus. In control, no inhibitory zone was observed.
CONTRACEPTIVE EFFICACY OF SOLANUM XANTHOCARPUM BERRY IN MALE RATS
Oral feeding of 50% EtOH of Solanum xanthocarpum berry to male rats at the dose of 0.5 gm/kg body weight caused arrest of spermotagenesis. The number of spermatocytes (primary and secondary) and spermatids were significantly reduced (P<0.05 to 0.001). The total number of immature and mature leydig cells were significantly decreased (P<0.001), whereas degenerating cells were significantly increased (P<0.001). The decreased testicular cell population reflects antispermatogenic nature of Solanium xanthocarpum berry extract.
Is FSH required for maintenance of spermatogenesis in adult rats?
Administration of FSH antiserum to adult rats for 14 or 30 days had no or little effect on body, testis or accessory sex gland weights, androgen-binding protein, testosterone levels, germ cell numbers or fertility, thus indicating a relative insensitivity of the testis to withdrawal of FSH. Unlike immature rats, therefore, which do require FSH to initiate spermatogenesis, adult rats do not need this hormone to maintain spermatogenesis.