SiCp/Cu composites prepared by the dual-directional extrusion process of floating die
SiCp/Cu composites were fabricated by the dual-directional extrusion process of the floating die. The microstructure, wear behavior and conductivity of SiCp/Cu composites were studied by optical microscope, abrasion test and current conductivity instrument. The results show that the SiCp/Cu composites with SiC particle distributed uniformly can be obtained, and the conductivity of composites decreased with the increasing of concentration of SiC particles, the wear resistance behavior of SiCp/Cu composites is evidently better than Cu with the increasing of concentration of SiC particles, the wearing mechanism of composites is a synthetically combined function of micro-cutting wearing and surface peeling off and grain wearing.
Study on Preparation and Properties of New Cu-based Composite
Copper-coated carbon fiber-graphite-copper matrix composite,carbon nanotube-graphite-copper matrix composite and graphite-copper matrix composite were prepared by powder metallurgy.The properties of the composites,such as density,resistivity,Vickers hardness and bend strength,were tested,the microstructure is observed and then the comprehensive performance was compared with each other.The results show that carbon fiber-graphite-copper matrix composite is of the most excellent performance in the three composites.
Amphotericin B microspheres: A therapeutic approach to minimize toxicity while maintaining antifungal efficacy
Amphotericin B microsphere formulations with and without addition of polyethylene glycol 2000 in cross-linked bovine serum albumin were prepared. Amphotericin B microspheres were characterized for particle size (<5 µm), zeta potential (∼30 mV) and drug interaction by DSC and FTIR and were found to be stable formulations. Drug release profiles for these microspheres revealed that the release was primarily by diffusion. In vitro toxicity as assessed by release of haemoglobin and potassium demonstrated no toxic effect as compared with conventional solution formulation. Antifungal activity in vitro was comparable to solution formulation when tested by broth dilution method.