Local and Regional Economic Impacts of Biofuel Development
Expanded processing of agricultural products in rural areas has been widely pursued as a strategy for rural economic development. By adding value to farm products before they leave the area, new processing plants can create new employment opportunities and generate economic spinoffs in rural areas that have experienced economic stagnation or decline as a result of long term trends of farm consolidation. In addition, farmer owned processing facilities provide a way for producers to integrate forward and capture potential profits from processing and marketing their products. Consequently, the expansion of agricultural processing in rural areas usually receives broad-based support from commodity groups, rural development interests, and state political leaders. In recent years, the most prevalent type of new agricultural processing ventures in the Midwest and Great Plains states has been corn ethanol plants. Like other types of agricultural processing, these biofuel ventures have generally received widespread support, and numerous studies have addressed their contributions to local or regional economies. However, while the methods employed have seemingly been quite similar, the findings have varied widely with the impacts attributed to ethanol development differing as much as ten-fold. The purpose of this paper is to (1) examine reasons why estimates of local or regional economic impacts of biofuel development may vary and (2) compare the economic impacts of corn-based ethanol production with those expected to be associated with cellulosic ethanol production.
The Role of Information Technology in the Fuel Ethanol Industry
This USDA-sponsored study uses panels of ethanol industry experts and follow up interviews with plant owners and managers to examine how information technology has impacted the structure, organization, and operations of the fuel ethanol industry. The study examined the following questions regarding the future of the ethanol industry: (1) Does the present ethanol industry represent a stable structure or a transitional step toward an inevitable concentration of ownership into the hands of a few large processing firms? (2) Have contemporary information technologies fundamentally changed the information flows, scale of operations, access to markets, conditions of vertical and horizontal coordination, sources of finance, and the competitive landscape for the medium-sized, independent processing firm? (3) To what degree have cost savings associated with better access to information and financing offset the cost savings traditionally associated with horizontal and vertical integration in processing industries? (4) What steps do medium-sized ethanol production entities need to take to continue to survive in this new information-based market environment?
Calyculins and Related Marine Natural Products as Serine-Threonine Protein Phosphatase PP1 and PP2A Inhibitors and Total Syntheses of Calyculin A, B, and C
Calyculins, highly cytotoxic polyketides, originally isolated from the marine sponge Discodermia calyx by Fusetani and co-workers, belong to the lithistid sponges group. These molecules have become interesting targets for cell biologists and synthetic organic chemists. The serine/threonine protein phosphatases play an essential role in the cellular signalling, metabolism, and cell cycle control. Calyculins express potent protein phosphatase 1 and 2A inhibitory activity, and have therefore become valuable tools for cellular biologists studying intracellular processes and their control by reversible phosphorylation. Calyculins might also play an important role in the development of several diseases such as cancer, neurodegenerative diseases, and type 2-diabetes mellitus. The fascinating structures of calyculins have inspired various groups of synthetic organic chemists to develop total syntheses of the most abundant calyculins A and C. However, with fifteen chiral centres, a cyano-capped tetraene unit, a phosphate-bearing spiroketal, an anti, anti, anti dipropionate segment, an α-chiral oxazole, and a trihydroxylated γ-amino acid, calyculins reach versatility that only few natural products can surpass, and truly challenge modern chemists’ asymmetric synthesis skills.