VEGETABLE PURGATIVES CONTAINING ANTHRACENE DERIVATIVES
In Part I of this series of papers1 reference was made to a preliminary test on an extract of Senna pod which was found to contain only about 5 per cent. of its theoretical activity. Biological and chemical tests have since been carried out on a number of galenical preparations of senna pod and the results have confirmed that only a small proportion of the activity of the pod is present in these concentrated preparations. The ultimate aim of the work described in this paper has been to devise a method of preparing an extract representing the full activity of the pod from which it was made, and as a result, it has been possible to set out the principles underlying efficient extraction and concentration processes.
THE CHEMICAL ASSAY OF CASCARA
THE bark of cascara (Rhamnus purshiunus DC.) is believed to contain free emodin, aloe-emodin, and chrysophanol. The purgative activity of the drug is thought to be due not to these free anthraquinones, but to glycosides of the anthranols (or of the oxanthrones) corresponding to some or all of them. Little is known about the structure of such glycosides, except that Schindlerl has reported the isolation of a glycoside of emodin oxanthrone (I).
Comparative Policies of Legal Provisions for Plant Closure: Strike a Balance?
The article aims to explore the extent to which and how plant closure laws strike a balance between job security and managerial prerogative and assess the practical effects of legal provisions. To achieve this aim, the forms of underlying doctrines of legal provisions, and substantial and procedural requirements are deliberately examined by cross-national (i.e. UK, Germany, and Japan) comparisons. The findings reveal that the legal provisions of the selected nations do not seek to diminish management rights to close plants down. Instead, they attempt to impose more democratic control over the liberty and mobility of capital by negotiating with and compensating the affected workers.