Coincident Imaging and Spectrometric Observations of Zenith OH Nightglow Structure
During the ALOHA-90 campaign a novel comparative study was made between near infrared wave structure imaged in the zenith using a CCD camera and that detected at infrared wavelengths by a Fourier Transform Spectrometer. Coincident measurements were made briefly on several occasions and for an extended period on 31 March. The temporal variations imaged in the near infrared structure during this night almost completely matched those detected in the OH (3,1) band spectrometer data when similar viewing fields were compared. However, the image data also displayed small scale wave forms that were not resolved by the larger field instrument. These structures exhibited significant changes in brightness and position on a time scale much shorter than the local Brunt-Vaisala period indicating that very high resolution measurements are necessary to investigate short period (<20 min) upper atmospheric wave motions.
Introduction to ALOHA‐90: The airborne lidar and observations of the Hawaiian Airglow Campaign
The middle atmosphere is a region of complex photochemical and dynamic interactions. Stretching from roughly 30 to 100 km altitude, this is the transition region between the stratosphere and thermosphere and is perhaps the least understood region of the earth's atmosphere. A variety of interesting and important structures are found in this region including the ozone layer, noctilucent clouds, the airglow layers, the meteoric metal layers and the recently discovered sporadic Na and Fe layer phenomena.
Semiautomated quantification of the fibrous tissue response to complex three-dimensional filamentous scaffolds using digital image analysis.
Fibrosis represents a relevant response to the implantation of biomaterials, which occurs not only at the tissue-material interface (fibrotic encapsulation) but also within the void fraction of complex three-dimensional (3D) biomaterial constructions (fibrotic ingrowth). Usual evaluation of the biocompatibility mostly depicts fibrosis at the interface of the biomaterial using semiquantitative scores. Here, the relations between encapsulation and infiltrating fibrotic growth are poorly represented. Virtual pathology and digital image analysis provide new strategies to assess fibrosis in a more differentiated way. In this study, we adopted a method previously used to quantify fibrosis in visceral organs to the quantification of fibrosis to 3D biomaterials. In a proof-of-concept study, we transferred the "Collagen Proportionate Area" (CPA) analysis from hepatology to the field of biomaterials. As one task of an experimental animal study, we used CPA analysis to quantify the fibrotic ingrowth into a filamentous scaffold after subcutaneous implantation. We were able to demonstrate that the application of the CPA analysis is well suited as an additional fibrosis evaluation strategy for new biomaterial constructions. The CPA method can contribute to a better understanding of the fibrotic interactions between 3D scaffolds and the host tissue responses.