Asymmetric oxidation of 2-(arylsulfenyl)pyrroles
The asymmetric oxidation of prochiral 2-(arylsulfenyl)pyrroles has been investigated. A marked electronic effect within the substrate significantly influenced the degree of enantioselectivity obtai...
Comparison of benzene, nitrobenzene, and dinitrobenzene 2-arylsulfenylpyrroles.
The effectiveness of the 2,4-dinitrobenzenesulfenyl and 4-nitrobenzenesulfenyl groups as masking and directing groups at the 2-position of pyrrole has been investigated and compared to that of 2-phenylthiopyrrole. The presence of the nitro group(s) enhances stability of the corresponding pyrrole toward acid and does not significantly decrease the ability of the pyrrolic unit to undergo electrophilic aromatic substitution reactions in the form of formylation, nitration, and condensation with aldehydes. The synthetic utility of 2-(2,4-dinitrobenzenesulfenyl)pyrrole was demonstrated through the synthesis of meso-substituted dipyrromethanes. The sulfoxides 2-(2,4-dinitrobenzenesulfinyl)pyrrole and 2-(4-nitrobenzenesulfinyl)pyrrole underwent neither formylation nor nitration, and the increasing presence of nitro groups within the moiety at the 2-position resulted in decreased stability under acidic conditions.
The Diminishing Role of Social Work Administrators in Social Service Agencies
ABSTRACT The social service industry in the United States has experienced tremendous growth and change since the early 1970s. Unfortunately, the social work profession has not kept up with this growth and change. This article explores several issues that have emerged in social work administration that may contribute to the seemingly diminished role of social workers in administrative positions in social service agencies. They include the role that schools of social work play in educating social workers for administration, competition for administrative positions in social service agencies, and the differences which exist between administration in social service agencies and other types of organizations.