Contact sensitization to organosilane solution in glass filament production
Glass filaments have been commercially produced since the 1930s, and are now mainly used for reinforcing plastics, paper, textiles, floorings, boats, and bituminous products, and rendering appliances like pipes and tanks corrosion-resistant. During production, filaments are coated with a water dispersion of epoxy resins, polyester resins, silane compounds, emulsifiers, lubricants, surfactants and antistatic agents. Various silanes are used as bonding agents between glass and resin in the final product. 2 studies have recently reported sensitization to silanes (1, 2).
Occupational contact dermatitis from amine‐functional methoxysilane in continuous‐glass‐filament production
with cephalosporins, as they all share a beta-lactam ring (17). Nevertheless, cases of allergy to amoxycillin with tolerance to other penicillins have been reported and the importance accorded to side-chain penicillin determinants has increased (18-22). The lack of general cross-sensitivity between beta-lactams in our patients supports the importance of such ·antigenic determinants. Patch testing, prick testing, and intradermal testing (with immediate and delayed readings) are all recommended in suspected beta-lactam antibiotic allergy, though with appropriate precautionary measures (23).
Batch-consciousness in dermatologic management.
The chemical ingredients can vary between batches of industrial products. That means that the sensitizing capacity is also variable. This should be considered in taking histories, performing patch testing and analyzing chemicals.