Computational investigation on infrared radiation characteristic for two-dimensional vectoring nozzles with fluidic injection
Relative to the thrust vectoring nozzle by mechanical means, fluidic injection vectoring nozzle outshines on the strength of uncomplicated structure, light weight and low cost. Research on infrared characteristic of fluidic injection vectoring nozzles is highly vital for nozzle technology development and military application. Numerical simulation for infrared characteristic of the two-dimensional fluidic injection vectoring nozzles was conducted employing self-developed program software. Based on the computational results, it can be concluded that two-dimensional throat skewing nozzle possesses optimal infrared characteristic suppression effect among the nozzle schemes.
ADVANCES IN THRUST VECTORING AND THE APPLICATION OF FLOW-CONTROL TECHNOLOGY
A review of thrust-vectoring initiatives shows thrust-vectoring technology to be a proven concept that enhances the projection of aerospace power with many advantages, including improved aircraft maneuverability, performance, survivability, and stealth. Mechanical thrust-vectoring designs, however, have proven to be heavy, complex, expensive, and counter-productive to stealth. Fluidics offer reduced weight, higher reliability, and stealth compatibility. Fluidic thrust- vectoring systems have been successfully tested; although, flight testing has yet to be completed. A thrust-vectoring upgrade programme would benefit the CF-18 aircraft in retaining its viability to project Canadian aerospace power until the end of its service life.
Rational Design, Synthesis and Evaluation of γ-CD-Containing Cross-Linked Polyvinyl Alcohol Hydrogel as a Prednisone Delivery Platform
This study describes the in-silico rational design, synthesis and evaluation of cross-linked polyvinyl alcohol hydrogels containing γ-cyclodextrin (γ-CDHSAs) as platforms for the sustained release of prednisone (PDN). Through in-silico studies using semi-empirical quantum mechanical calculations, the effectiveness of 20 dicarboxylic acids to generate a specific cross-linked hydrogel capable of supporting different amounts of γ-cyclodextrin (γ-CD) was evaluated. According to the interaction energies calculated with the in-silico studies, the hydrogel made from PVA cross-linked with succinic acids (SA) was shown to be the best candidate for containing γ-CD. Later, molecular dynamics simulation studies were performed in order to evaluate the intermolecular interactions between PDN and three cross-linked hydrogel formulations with different proportions of γ-CD (2.44%, 4.76% and 9.1%). These three cross-linked hydrogels were synthesized and characterized. The loading and the subsequent release of PDN from the hydrogels were investigated. The in-silico and experimental results showed that the interaction between PDN and γ-CDHSA was mainly produced with the γ-CDs linked to the hydrogels. Thus, the unique structures and properties of γ-CDHSA demonstrated an interesting multiphasic profile that could be utilized as a promising drug carrier for controlled, sustained and localized release of PDN.