Using catalog data mining in support of determining micro end-milling conditions
A growing number of requirements are being placed on micro fabrication using end mills with high operating degrees-of-freedom. In particular, when the minor diameter of the end mill is 1.0 mm or less, the handling of tools becomes difficult because of the influence of the characteristic size effect and bending of the cutting portion. Furthermore, it is hard for engineers to derive the cutting conditions that can serve as indexes in the early stage of end-milling with small minor diameters. To solve this problem, in this research, on a basis of workpiece material characteristics and tool shape parameters, a system that can make instantaneous decisions on the tool shape and cutting conditions to be used was built, and its usefulness was evaluated. This system was developed by applying data mining techniques together with non-hierarchical and hierarchical clustering methods on tool catalog data. The results of the analysis found that the characteristics of the workpiece material were significant in making decisions regarding the cutting conditions for the minor diameter of the end mill. Moreover, the cutting speed was found to have a significant effect on the tool shape parameters, whereas differences as to the processing method (side milling or slotting) did not have a significant effect.
Cutting Condition Decision Methodology Based on Data-Mining of Tool Catalog Data
Data-mining methods were used to support decisions about reasonable cutting conditions. The aim of our research was to extract new knowledge by applying data-mining techniques to a tool catalog. We used both hierarchical and non-hierarchical clustering of catalog data and also used applied multiple regression analysis. We focused on the shape element of catalog data and we visually grouped end mills from the viewpoint of tool shape, which here meant the ratio of dimensions, by using the k-means method. We then decreased the number of variables by using hierarchical cluster analysis. We also found an expression for calculating the best cutting conditions, and we compared the calculated values with the catalog values. We did 15 minutes of cutting work using three kinds of cutting conditions: conditions recommended in the catalog, conditions derived by data-mining, and proven cutting conditions for die machining (rough processing).Copyright © 2010 by ASME
In Vivo Comparison of Synthetic Macroporous Filamentous and Sponge-like Skin Substitute Matrices Reveals Morphometric Features of the Foreign Body Reaction According to 3D Biomaterial Designs
Synthetic macroporous biomaterials are widely used in the field of skin tissue engineering to mimic membrane functions of the native dermis. Biomaterial designs can be subclassified with respect to their shape in fibrous designs, namely fibers, meshes or fleeces, respectively, and porous designs, such as sponges and foams. However, synthetic matrices often have limitations regarding unfavorable foreign body responses (FBRs). Severe FBRs can result in unfavorable disintegration and rejection of an implant, whereas mild FBRs can lead to an acceptable integration of a biomaterial. In this context, comparative in vivo studies of different three-dimensional (3D) matrix designs are rare. Especially, the differences regarding FBRs between synthetically derived filamentous fleeces and sponge-like constructs are unknown. In the present study, the FBRs on two 3D matrix designs were explored after 25 days of subcutaneous implantation in a porcine model. Cellular reactions were quantified histopathologically to investigate in which way the FBR is influenced by the biomaterial architecture. Our results show that FBR metrics (polymorph-nucleated cells and fibrotic reactions) were significantly affected according to the matrix designs. Our findings contribute to a better understanding of the 3D matrix tissue interactions and can be useful for future developments of synthetically derived skin substitute biomaterials.