Synthetic analogs ofPeganum alkaloids. I. Synthesis of methoxy- and hydroxy-substituted deoxyvasicinones and deoxypeganines
Abstract6-Methoxy-, 7-methoxy-, and ′8-methoxydeoxyvasicinones have been synthesized by the reaction of substituted (3-methoxy-, 4-methoxy-, and 5-methoxy-) anthranilic acids with α-pyrrolidone. The demethylation of these compounds has given the corre-sponding hydroxy-substituted analogs of deoxyvasicinone, and the reduction of the products obtained with zinc in hydrochloric acid has given the hydroxy- and methoxy- analogs of deoxypeganine. 8-Hydrooxydeoxypeganine dimethyl-, ethyl-, and butylcarbamates have been obtained by the carbamoylation of 8-hydroxydeoxypeganine.
Die Reaktion cyclischer Lactimäther mit Aminocarbonsäuren
Cyclische Lactimather reagieren mit aliphatischen und aromatischen, Aminocarbonsauren zunachst unter Bildung offenkettiger amidinartiger Verbindungen, die in der aliphatischen Reihe nur schwer zum Ring geschlossen werden konnen. Der Ringschlus vollzieht sich bei aromatischen und heterocyclischen o-Amino-carbonsauren sehr leicht. Die neue Synthese macht auch das Alkaloid Rutaecarpin (XV) leicht zuganglich.
Measurement of sulfate and sulfur dioxide in automotive exhaust. Final report, 28 Jun 1974--31 Aug 1976
The testing of four groups of cars for sulfate and sulfur dioxide exhaust emissions is described. The collection and analytical techniques used for sulfate and sulfur dioxide are described. Emissions rates in grams per kilometre are presented for a variety of test cycles. In addition to sulfates and sulfur dioxide, gaseous emissions of hydrocarbons (HC), carbon monoxide (CO) and oxides of nitrogen (NOx) are reported in grams per kilometre. Total particulate weight on the sulfate filter was determined on two of the groups of cars. For these same two groups of cars, the sampling tunnel residue from each test car was examined by x-ray fluorescent techniques. The first of the car groups was tested to characterize sulfate emissions from eight automobiles. Four of these were gasoline powered catalyst cars, three were gasoline powered noncatalyst cars, and one was diesel powered. The second group, four catalyst cars, was operated for 80,500 km (50,000 miles) to determine the effect of distance accumulation on sulfate emissions. The third group, two 1975 production catalyst cars, was part of the EPA sulfate procedural development testing. The last group, eight cars, was part of the EPA sulfate baseline. Of these cars, six were production 1975 modelsmore » (including one diesel), and two were experimental cars with three-way catalysts.« less