Canada and the institute of pacific relations: Lessons from an earlier voyage
Woods suggests that valuable lessons can be learned from Canada's involvement in the Institute of Pacific Relations (IPR) which will aid and inform its current Asia‐Pacific relations. Two arguments are made in this paper: that interaction with the IPR has shaped current Canadian attitudes towards regional institutions; and that a form of 1920s track‐two diplomacy is alive today in Canada. Canadian interaction with the IPR is examined through: the impact the Institute had on the leader of the Canadian delegation to the first IPR conference, John Nelson, and his subsequent contributions to Canada's early track two diplomacy; the impact that the Canadian academic/diplomat E. Herbert Norman had on the Institute and Canada's Asia‐Pacific persona; the state‐society relationship within Canada vis‐a‐vis the IPR; and the role of American philanthropy in sustaining Canadian contributions to the Institute. Woods concludes that the belief in track‐two diplomacy is alive and well in Canada; that the utility of a broad...
Canada's goal in the Asia Pacific
Abstract Canada's chief goal in the Pacific is to gain a greater share in the economic growth of East Asia while promoting regional stability through middle power multilateralism. Like other Western countries in the Pacific Canada should strongly support trans‐oceanic groups like the ASEAN PMCs and the APEC group as well as the numerous non‐governmental organizations devoted to keeping the countries on both sides of the Pacific cooperating together, both developed and developing. Both the US under Clinton and Canada under Chretien seem to believe the economic future of their countries depends to a significant extent on participating in East Asian economic development. Giving good economic relations precedence over sanctions suggests that they have committed themselves to that course. If successful, Canada's regional activism may help to counter its weakening European ties and its greater absorption into North America, and it may help to increase its foreign influence and independence.
Stereoselective disposition of ibuprofen enantiomers in infants.
The pharmacokinetics of the enantiomers of ibuprofen were investigated after oral administration of a single 7.6 +/- 0.3 mg kg-1 dose of the racemate in 11 infants. Mean (+/- s.d.) half-lives were 1.6 +/- 0.5 h for S(+) and 1.5 +/- 0.5 h for R(-) and mean (+/- s.d.) AUC values were 31.5 +/- 14.3 mg l-1 h for S(+) and 36.6 +/- 13.8 mg l-1 h for R(-). Since plasma concentrations of the active S(+)-isomer were lower than those reported in adults, a higher dosage might be required in infants.