Creating Citizenship Through Community Radio in Rural Thailand
This study seeks to analyze the ongoing social movement to establish community radio in rural Thailand as a participatory communication process in order to transform people into citizens. More specifically, the study analyzes the participatory process inherent in the development of community radio in Thailand since its inception in 1997 to the present and illustrates success cases of citizen empowerment. The study is based on analysis of documents and secondary data, personal observation and interview of key persons, field study and case studies of numerous community radio stations. The study showed that the movement was triggered off by the 1997 Constitution which advocated a participatory democracy and reallocation of radio frequencies for public interests at all levels. To vie for frequency allocation, a number of government, non-government, public and private agencies rushed to set up community radio as a pilot station. As a result of the failure to establish a national broadcasting regulator as stipulated by the Constitution, most small radio stations had been operated illegally and in a chaotic state. However, there was some evidence suggesting that participatory community radio, particularly hill tribe radio, has the potential to transform rural people into active citizens due to radio’s ability to involve and empower the grassroots as well as to treat its listeners as subjects and participants rather than as objects or passive audiences.
Community Radio in the West
In this article the legacy of struggle by community radio in the West is analysed from a comparative perspective. More specifically, the focus of this article is on Western media policies towards community radio. It is argued that while many community radio discourses, theories and policies are oriented towards developing countries and emerging democracies, community radio stations in the West are often forced to operate in the margins. Case studies on the US, the UK and Belgium are presented. Some influence of distinct regulatory paradigms can be observed, but overall in each of these countries community radio stations have a legacy of struggle for their existence and survival. This exposes the need to account for the distinct nature of community radio in (Western) regulatory regimes. A common thread in the cases being presented is the difficulty involved in (local) community radio legitimating its existence on the FM-band alongside commercial and public broadcasters. Unlike these, community radio movements have little lobbying power and are usually positioned as rogue and unprofessional actors within the broadcasting community. From a democratic perspective emphasizing the importance of participation and civic culture, Western media policies urgently need to create an enabling environment for participatory community radio initiatives.
Pharmacokinetics and Metabolism of 14C-Brivaracetam, a Novel SV2A Ligand, in Healthy Subjects
This study was designed to investigate the human absorption, disposition, and mass balance of 14C-brivaracetam, a novel high affinity SV2A ligand with potent anticonvulsant activity. Six healthy male subjects received a single p.o. dose of 14C-brivaracetam (150 mg, 82 μCi, or 3.03 MBq). Serial blood and complete urine and feces were collected until 144 h postdose. Expired air samples were obtained until 24 h. Brivaracetam was rapidly absorbed, with Cmax of 4 μg/ml occurring within 1.5 h of dosing. Unchanged brivaracetam amounted to 90% of the total plasma radioactivity, suggesting a modest first-pass effect. Plasma protein binding of radioactivity was low (17.5%). Urinary excretion exceeded 90% after 2 days, and the final mass balance reached 96.8% of the radioactivity in urine and 0.7% in feces. Only 8.6% of the radioactive dose was recovered in urine as unchanged brivaracetam, the remainder being identified as non–cytochrome P450 (P450)- and P450-dependent biotransformation products resulting from hydrolysis of the amide moiety (M9, 34.2%), hydroxylation of the n-propyl side chain (M1b, 15.9%), and a combination of these two pathways leading to the hydroxy acid (M4b, 15.2%). Minor amounts of taurine and glucuronic acid conjugates and other oxidized derivatives were also identified. Brivaracetam is completely absorbed, is weakly bound to plasma proteins, extensively biotransformed through several metabolic pathways, and eliminated renally.