Enantioselective total synthesis of the indole alkaloid 16-episilicine.
The first total synthesis of (-)-16-episilicine has been completed from a phenylglycinol-derived bicyclic lactam, the key steps being stereoselective conjugate addition and alkylation reactions, and a ring-closing metathesis.
One pot hydroamination/[4 + 3] cycloaddition: synthesis towards the cyclohepta[b]indole core of silicine and ervatamine
A new and facile tandem reaction of intramolecular hydroamination and novel [4 + 3] cycloaddition was developed for the synthesis of multitudinal indole-containing 5,7,6-tricyclic skeletons. This method was further extended to the quick synthesis of a series of useful motif of natural products, such as the core of ervatamine and silicine.
Annual review article: Is it time to rethink the gender agenda in entrepreneurship research?
This article develops a critique of contemporary approaches to analysing the impact of gender upon entrepreneurial propensity and activity. Since the 1990s, increasing attention has been afforded to the influence of gender on women’s entrepreneurial behaviour; such analyses have highlighted an embedded masculinity within the entrepreneurial discourse which privileges men as normative entrepreneurial actors. While invaluable in revealing a prevailing masculine bias within entrepreneurship, this critique is bounded by positioning women as a proxy for the gendered subject. This is a potentially limiting analysis that does not fully recognise gender as a human property with myriad articulations enacted throughout entrepreneurial activity. To progress debate, we engage more deeply with the notion of gender as a multiplicity, exploring the implications of such for future studies of entrepreneurial activity.