The distant shielding effect in trinucleoside diposphates
A comparative study on the proton magnetic resonance of the dinucleoside monophosphates TpT, dApT, TpdA, the trinucleoside diphosphates dApTpT, TpTpdA, and poly T has been made. The purpose of this investigation was to establish whether in a trimer the proton chemical shifts of one terminal residue are influenced by the magnetic anistropy of the other terminal residue. The conformation of the trimers was first studied and shown to the similar to that of the corresponding dimer, except that of the percentage of the lefthanded conformers in the population of the trimers is probably lower than in the population of the dimers. The methylprotons, H‐6, and H‐1′ of the 3′‐terminal T residue in TpTpdA (or the 5′‐terminal T residue in dApTpT) are found to be more upfield than the same protons on the dimer TpT up to a magnitude of about 0.1 ppm. The shielding of these protons of the terminal T(s) in these trimers is even larger than those corresponding protons in the poly(T) at the same condition. From these results, it is concluded that a distant shielding effect is exerted by the 5′‐terminal. A residue (or by the 3′‐terminal A residue) on the other terminal residue in the trimers studied.
Intermolecular nuclear shielding values for protons of purines and flavins.
Abstract The association of aromatic molecules through vertical stacking produces an upfield shift of the proton resonance lines of these compounds with respect to the isolated molecules. This increase of the proton shielding is due mainly to the additional magnetic field created by the ring currents of the neighbours. This paper presents the results of calculations of the isoshielding (Δδ) due to the ring current of biologically essential purines, pyrimidines and flavins at different points of a parallel plane situated at the 3.4 A distance. The usefulness of these results for the conformation of molecular associations is indicated.
Electrothermal Measurements of Bridgewires Used in Electroexplosive Devices
The bridgewire of an electroexplosive device is evaluated for its thermal response to impulse energy and to square-wave power. Thermal time constant and basic electrothermal parameters can be measured from the response. These parameters are useful in the study and characterization of electroexplosive devices.