A method for hermetically packing solid medicinal forms
Four basic methods are in existence for protecting solid drugs from external influences: i) coating of tablets with a film by pelleting or in a fluidized bed; 2) packaging preparations in polymeric film materials; 3) packaging in metal foil; 4) packaging in mixed films consisting of aluminum foil and cellophane, polypropylene, or other polymeric material. This method has the widest application at the present time. Methods have been developed not only for packaging in mixed films but also automatic lines of diverse productivity have been established.
Evaluative procedures for filmforming materials used in pharmaceutical applications.
The current interest in films for use in many pharmaceutical applications has motivated a study in which meaningful testing procedures have been developed or adapted for evaluating such films. The testing procedures studied were found to be rapid, efficient, reproducible, and valid for the evaluation of the pertinent properties of several different series of film-forming materials. The studies were conducted on the free films which were cast from these materials. Data gathered on solubility, moisture absorption, water vapor transmission rates, and the effects of temperature, humidity, and light on the free films indicate that the testing methods may be used to predict the effects of these variables on the performance of the films when they are utilized in a dosage form.
Thermodynamics on the Carbochlorination of Titanium-bearing Ores
The equilibrium compositions of the multi-component, multi-phase and multi-reaction system of carbochlorination of titanium-bearing ores are calculated with HSC, a computational chemistry software. The thermodynamic equilibrium calculation of the reaction system shows that a complete conversion of titanium-bearing ores is feasible at a temperature near 200oC. At temperatures ranging from 800 to 1600oC, the products of the reaction system are all in gaseous phase. Thermodynamic analysis accords with the industrial practice. The simulated results provide reasonable scientific basis for improving suitable technological conditions of the carbochlorination reduction.