Trefolane A, a sesquiterpenoid with a new skeleton from cultures of the basidiomycete Tremella foliacea.
Trefolane A (1), an unprecedented skeleton with a 5/6/4 tricyclic ring system, was isolated from cultures of the basidiomycete Tremella foliacea. The structure was elucidated by means of spectroscopic methods and further confirmed by single crystal X-ray diffraction analysis. A possible biogenesis for trefolane A (1) was also proposed.
Non-isoprenoid botryane sesquiterpenoids from basidiomycete Boletus edulis and their cytotoxic activity
Three non-isoprenoid botryane sesquiterpenoids, named boledulins A-C (1–3), have been isolated from the cultures of basidiomycete Boletus edulis Bull. The structures were established by means of spectroscopic methods. Boledulin A (1) exhibited moderate inhibitory activity against five human cancer cell lines.
Phloroglucinol derivatives from Hypericum japonicum.
The isolation and identification of a new phloroglucinol derivative (2), a diterpenol (4), together with the known compounds flavesone (1) and sarothralen B (3), from the aerial parts of Hypericum japonicum are reported. Their structures were established by extensive spectral analysis and the structure of (3) has also been confirmed by a single crystal X-ray determination.