Chemical structure and fungicide selectivity
The influence of stereo- and other isomers, homologues and structural variations on the activity of various types of systemic fungicides is reviewed.
Investigations on fungicides: XIV. Fungitoxicity of N‐(2,2,2–trichloro‐1–methoxyethyl)‐formamide and related compounds
SUMMARY 
 
From a study of forty compounds related to the systemic fungicide N,N'-bis(1–formamido-2,2,2–trichloroethyl)-piperazine, known as triforine (CELAW524), it was found that a new compound, N-(2,2,2–trichloro-1–methoxyethyl)-formamide, controls Erysiphe graminis on wheat when applied to the roots in sand. A number of N-(2,2,2–trichloro-1–aryloxyethyl)-form-amides and alkyl N-(2,2,2–trichloro-1–arylaminoethyl)-carbamates protect broad beans against Uromyces fabae and wheat against Erysiphe graminis; some of these formamides show slight activity when applied to plant roots.
Studies in fungitoxicity. V. Fungicidal activity of certain dithiocarbamates.
Forty-nine derivatives of dimethyldithiocarbamic acid: dimethyldithiocarbamoylamides, N-(dimethyl- dithiocarbamoylalkyl)-amides, -acid esters and -ethers and related compounds were synthesised and tested for fungitoxicity. Of the amides, only those compounds that readily split off the dimethyl-dithiocarbamate ion, detected by a brown colour with copper acetate, had high activity against Venturia inaequalis. Of six ethylenebis-S-alkanamidoalkyl dithiocarbamates, all of which readily yielded the ethylenebisdithiocarbamate ion, only those with a trichloromethyl substituent had high activity. Of the other new condensation products of N-(l,2,2,2-tetrachloroethyl)amides with various nucleophiles, only the 8-oxinate was highly active.