Studies Towards the Synthesis of the Core of Endiandric Acid H
In the presence of a CuBr·SMe2 catalytic system, a very simple and efficient approach for the synthesis of the key precursor of the core of endiandric acids starting from the readily and abundantly available 3-butyn-1-ol in five linear steps with an overall yield of 40% was developed.
Synthesis and biological profiling of half-calycanthaceous alkaloid analogues
Abstract During our continuous efforts to pursue antifungal agents, some calycanthaceous alkaloid analogs showed diverse and promising bioactivities. Therefore, 34 new calycanthaceous alkaloid derivatives were further prepared and screened for bioactivities. As a result of the evaluation against a great deal of plant pathogen fungi, bacteria and human pathogenic fungi, a majority of them displayed potent bioactivity. In particular, compound b6 displayed remarkably activity and might be novel potential leading compound for further development of antifungal agent. The relationship between structure and biological activity was also discussed. Graphical abstract
Public health in eight European countries: an international comparison of terminology.
OBJECTIVES
The aim of this paper was to assess the use of different terms pertaining to public health in selected Member States of the European Union.


STUDY DESIGN AND METHODS
Qualitative research methods were used to compare the terminology among eight Member States. Seven to nine core terms were defined for each country, and a search was performed for these terms in the names of institutions and professional titles, organized into three comparable categories.


RESULTS
The data analysis showed considerable diversity in terminology. The three most commonly used terms for each country, and the frequency distribution of the core terms for all eight countries were determined.


CONCLUSION
Public health terminology and underlying concepts vary among Member States of the European Union. A large number of loosely related terms are in use, indicating the lack of a common conceptual framework for the discipline of public health. The most commonly used terms pertaining to public health are 'health sciences' and 'health promotion'. 'Public health' is not among the most commonly used terms.