1,5-Naphthyridines and their n-oxides III. Synthesis and biological activity of some mono- and disubstituted 1,5-naphthyridines and their n-oxides
In order to search for biologically active compounds in the 1,5-naphthyridine series, we synthesized 2-mercaptoand 2-(4'-aminobenzenesulfonamido)-l,5naphthyridines and some of their 6-substituted derivatives. 2-(4'-Aminobenzenesulfonamido)-l,5-naphthyridine (I) was obtained by reaction of 2-amino-l,5naphthyridine with 4-carbomethoxyaminobenzenesulfonyl chloride in pyridine with subsequent saponification of the carbomethoxy group in the resulting 2-(4'carbomethoxyaminobenzenesulfonamido)-l,5-naphthyridine (II).
Tautomerism of 3-alkoxycarbonylmethylene-2-oxo-1,2,3,4-tetrahydroquinoxaline derivatives
The compound previously formulated as ethyl 1,2-dihydro-2-oxoquinoxalin-3-ylacetate has the isomeric structure 3-ethoxycarbonylmethylene-2-oxo-1,2,3,4-tetrahydroquinoxaline in the solid state. In solution the 1-methyl derivative has been shown by nuclear magnetic resonance studies to exist as a tautomeric mixture of unsaturated and saturated esters.
Asymptotic Properties of Solutions to Second-Order Difference Equations of Volterra Type
<jats:p>We consider the discrete Volterra type equation of the form <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi mathvariant="normal">Δ</mml:mi><mml:mo stretchy="false">(</mml:mo><mml:msub><mml:mrow><mml:mi>r</mml:mi></mml:mrow><mml:mrow><mml:mi>n</mml:mi></mml:mrow></mml:msub><mml:mi mathvariant="normal">Δ</mml:mi><mml:msub><mml:mrow><mml:mi>x</mml:mi></mml:mrow><mml:mrow><mml:mi>n</mml:mi></mml:mrow></mml:msub><mml:mo stretchy="false">)</mml:mo><mml:mo>=</mml:mo><mml:msub><mml:mrow><mml:mi>b</mml:mi></mml:mrow><mml:mrow><mml:mi>n</mml:mi></mml:mrow></mml:msub><mml:mo>+</mml:mo><mml:mrow><mml:msubsup><mml:mo stretchy="false">∑</mml:mo><mml:mrow><mml:mi>k</mml:mi><mml:mo>=</mml:mo><mml:mn mathvariant="normal">1</mml:mn></mml:mrow><mml:mrow><mml:mi>n</mml:mi></mml:mrow></mml:msubsup><mml:mrow><mml:mi>K</mml:mi><mml:mo stretchy="false">(</mml:mo><mml:mi>n</mml:mi><mml:mo>,</mml:mo><mml:mi>k</mml:mi><mml:mo stretchy="false">)</mml:mo><mml:mi>f</mml:mi><mml:mo stretchy="false">(</mml:mo><mml:msub><mml:mrow><mml:mi>x</mml:mi></mml:mrow><mml:mrow><mml:mi>k</mml:mi></mml:mrow></mml:msub><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mrow></mml:math>. We present sufficient conditions for the existence of solutions with prescribed asymptotic behavior. Moreover, we study the asymptotic behavior of solutions. We use <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M2"><mml:mi mathvariant="normal">o</mml:mi><mml:mo stretchy="false">(</mml:mo><mml:msup><mml:mrow><mml:mi>n</mml:mi></mml:mrow><mml:mrow><mml:mi>s</mml:mi></mml:mrow></mml:msup><mml:mo stretchy="false">)</mml:mo></mml:math>, for given nonpositive real <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M3"><mml:mrow><mml:mi>s</mml:mi></mml:mrow></mml:math>, as a measure of approximation.</jats:p>