[Studies on design for resin veneered crowns. 1. Adhesive resin luting agents reinforcement effect].
Resin veneered crowns show several drawbacks which affect the veneering resin: peeling, fracture, falling and also discoloration by leakages from the metal-resin border. The purpose of the present study is to find out a principle of resin veneered crown design allowing the solution of the above-mentioned problems. As a preliminary step, the influence of luting cements on the relative rigidity of veneered crowns and metal frameworks was examined by measuring the strain to static and impact charges on several portions of crowns. The investigation led to the following results: 1. The magnitude of the strain to a static charge increased with the number of shocks but beyond 100 shocks, no variation could be observed. 2. The magnitude of the strain to a static charge was proportional to the weight of the charge. 3. The strain of crowns and metal frameworks set with PanaviaEX had a magnitude smaller than the strain of those set with Fitchecker. 4. The strain to an impact charge had a magnitude 1-4 times larger than the strain to a static charge. 5. The adhesive resin luting agent reinforcement effect could be clearly confirmed.
Adhesive 4-META/MMA-TBB Opaque Resin with Poly(methyl methacrylate)-coated Titanium Dioxide
An adhesive opaque resin for veneering on cast metal was developed with 4-methacryloxyethyl trimellitate anhydride and poly (methyl methacrylate)-coated titanium dioxide prepared by aqueous phase polymerization. The opaque resin was a modified 4-META/MMA-TBB resin. The powder consisted of 20% of the encapsulated material and 80% PMMA instead of pure PMMA powder. This resin hides the metal color when the thickness of the resin is as thin as 50 μm. The opaque resin bonded strongly to both cobalt-chromium alloy and visible-light-cured veneering resin. This self-curing opaque resin is applicable not only for bonding veneering resin to an alloy surface but also for bonding fixed partial dentures to enamel surfaces.
Rational Design, Synthesis and Evaluation of γ-CD-Containing Cross-Linked Polyvinyl Alcohol Hydrogel as a Prednisone Delivery Platform
This study describes the in-silico rational design, synthesis and evaluation of cross-linked polyvinyl alcohol hydrogels containing γ-cyclodextrin (γ-CDHSAs) as platforms for the sustained release of prednisone (PDN). Through in-silico studies using semi-empirical quantum mechanical calculations, the effectiveness of 20 dicarboxylic acids to generate a specific cross-linked hydrogel capable of supporting different amounts of γ-cyclodextrin (γ-CD) was evaluated. According to the interaction energies calculated with the in-silico studies, the hydrogel made from PVA cross-linked with succinic acids (SA) was shown to be the best candidate for containing γ-CD. Later, molecular dynamics simulation studies were performed in order to evaluate the intermolecular interactions between PDN and three cross-linked hydrogel formulations with different proportions of γ-CD (2.44%, 4.76% and 9.1%). These three cross-linked hydrogels were synthesized and characterized. The loading and the subsequent release of PDN from the hydrogels were investigated. The in-silico and experimental results showed that the interaction between PDN and γ-CDHSA was mainly produced with the γ-CDs linked to the hydrogels. Thus, the unique structures and properties of γ-CDHSA demonstrated an interesting multiphasic profile that could be utilized as a promising drug carrier for controlled, sustained and localized release of PDN.