SYNTHESIS OF FLOTATION BASED SEPARATION SYSTEMS
In this work a methodology is presented for defining the optimal configuration for flotation circuit and selection of appropriate equipment for the process. The problem is represented by three hierarchized superstructures. The first level represents separation tasks, which include: feed processing, concentrate processing, and tail processing. The second level represents the stream network needed to carry out each tasks. Where for each task a superstructure is developed which includes several operational stages. At the third level, several equipment alternatives are considered for each stage. The equipment discussed in the model includes flotation column and flotation cell banks, with and without grinding. The optimal selection of the circuit is made with an appropriate objective function, upon which the values of the operational and structural variables may be determined. The problem is formulated using disjunctive programming, which is converted to a MILP problem. The model includes mass balance, equipment models, operational conditions, and logic relationship. The paper presents an example to illustrate its application for effective design of a copper concentration plant.
Relation between locked cycle tests and continuous plant circuit in flotation
Abstract It is important to elucidate the relation between the locked cycle flotation test and the continuous flotation circuit because the locked cycled test has been traditionally the only way to experimentally simulate a continuous circuit. We analytically assessed the mass balances of the locked cycle test in a rougher–cleaner–cleaner scavenger (R–C–CS) system as a function of the iteration number of tests and provided an analytical expression of the mass balance in each separation stage. The mass of the final concentrate and flotation characteristic curves in a continuous circuit and the locked cycle test were calculated using the flotation rate constant k and flotation time T . Based on the comparison of the calculated results between the two tests, a good agreement between the locked cycle test and the continuous circuit can be obtained when the kT value for a product component with the flotation rate constant k and time T is in the range where the mass of a component does not change with kT .
Immune dysfunction following infection with chicken anemia agent and infectious bursal disease virus. II. Alterations of in vitro lymphoproliferation and in vivo immune responses.
To determine the functional impact of alterations in lymphocyte concentrations and ratios following infection with chicken anemia agent (CAA) alone or in combination with infectious bursal disease virus (IBDV) on the immune system of young chickens, in vitro lymphoproliferation assays and in vivo responses to vaccination with several common viral agents were assessed at various time intervals post-inoculation (PI). Concanavalin A (Con A), phytohemagglutinin (PHA) and pokeweed mitogen (PWM) stimulation of splenic lymphocytes (SPL) collected from control birds could not be detected until 10-14 days PI. Infection with CAA was characterized by significantly higher PWM stimulation of SPL at 17 days PI and significantly lower PWM stimulation of peripheral blood lymphocytes (PBL) at 14 days PI, compared with uninfected controls. Concanavalin A and PWM stimulation of SPL was significantly increased in birds inoculated with IBDV alone. Lymphocytes harvested from birds inoculated simultaneously with CAA and IBDV had significantly lower responses. Effects on humoral and cell-mediated immunity following CAA and/or IBDV were determined by evaluating vaccination responses to Newcastle disease virus (NDV), fowl pox virus (FPV) and infectious laryngotracheitis virus (ILTV) during the acute phase of CAA infection (2 weeks PI). Vaccination of birds 2 weeks following CAA infection at 1 day of age resulted in decreased protection against NDV (85.7%) and ILTV (7.1%) challenge compared with protection rates in control birds (100% and 53.3% respectively). Infectious bursal disease virus infection was associated with decreased protection against NDV (60%) only. Concomitant infection at 1 day of age resulted in a greater reduction in NDV challenge protection (33.3%), slightly decreased FPV protection (87.5%), increased numbers of persistent FPV vaccination lesions and increased protection against ILTV challenge (71.4%). Vaccination of birds 2 weeks following CAA infection at 2 weeks of age resulted in slightly decreased NDV humoral antibody, development of persistent FPV vaccination lesions (17%) and increased immunity to ILTV challenge compared with control birds (83.3% vs. 66.7%). Chickens inoculated with IBDV alone displayed a more severe depression in NDV antibody titers and only a slight decrease in ILTV protection. Vaccination following concomitant infection at 2 weeks of age resulted in a higher percentage of FPV persistent vaccination lesions (39%) and greatly enhanced immunity to ILTV challenge (100%).