Experiment in relative permeabilities and two-phase transient theory
A series of pressure transients were observed at BR21, a high-enthalpy well. The variation in transient behavior with enthalpy gives some indication of the form of relative permeability functions for fractured media. The consistent form of the observed transients indicates that two-phase transient observations can be used to determine reservoir parameters.
The compressibility and hydraulic diffusivity of a water‐steam flow
Physical parameters are defined for a flow of water and steam in a porous medium: dynamic and kinematic viscosity, density, and compressibility. These permit single-phase pressure transient theory to be applied to two-phase flow provided that the pressure changes are not too large.
A peptide muscarinic toxin from the Green Mamba venom shows agonist-like action in an inhibitory avoidance learning task.
A peptide, muscarinic toxin 2 (MTX2), isolated from Dendroaspis angusticeps venom was previously shown to displace the specific binding of [3H]pirenzepine, a muscarinic M1 receptor ligand, from rat brain synaptosomal membranes. We have tested MTX2 for muscarinic agonist or antagonist actions in an inhibitory avoidance task in rats. Infusion of the muscarinic receptor antagonist scopolamine into the hippocampus of rats immediately after the training period produced amnesia, whereas the muscarinic agonist oxotremorine increased retention. When MTX2 was injected into the hippocampus of rats after the inhibitory avoidance task, it caused memory facilitation, which could be suppressed by the concomitant infusion of scopolamine. Hence, in this test, MTX2 showed muscarinic receptor agonist-like actions, which are probably mediated by the M1 subtype of muscarinic acetylcholine receptors.