A hypodermic pressure manometer utilizing the bonded wire resistance strain gauge.
The recent development of the bonded resistance wire strain gauge has led to its use as a device for measuring physiological pressure phenomena. Further application of the strain gauge has been as an instrument for measuring intravascular blood pressures and other pressure phenomena in biology and medicine.
A device for measuring physiologic pressure phenomena using the bonded electrical wire resistance strain gauge.
An electrical device for measuring physiological pressure phenomena, using a resistance wire strain gauge, is described. The gauge is bonded securely to a metal diaphragm, deformation of which changes the resistance of the gauge, and causes a flow of current through an appropriate circuit. Examples of the applications in physiology of this device are presented along with typical recordings.
Perturbed angular correlation study of a haptenic molecule.
The angular correlation of the 173-247 keV gamma-ray cascade after the electron-capture decay of (111)In is strongly perturbed when the 1-p-nitrophenyl-ethylenediaminetetraacetate chelate of (111)In(8+) is added to a solution containing rabbit antibody to dinitrophenyl groups. The radioactive chelate can be displaced by the addition of dinitrophenyllysine or unlabeled chelate. The average association constant between the antibody and the labeled chelate has been estimated from perturbed angular correlation measurements; this value is compared to the results of equilibrium dialysis. These experiments provide good evidence that information concerning macromolecular behavior can be obtained from perturbed angular correlation experiments that use chemically specific labels.