New synthesis of royal jelly acid
A new synthesis of (E)-10-hydroxy-2-decenoic acid (royal jelly acid) is described, starting from 8-bromo-1-octanol via condensation of malonic acid with 8-hydroxyoctanal or 8-acetoxyoctanal.
Reaktionen mit Phosphinalkylenen, XV. Eine Synthese der „Königinnensubstanz” und der trans-10-Hydroxy-decen-(2)-säure-(1) (royal jelly acid)
Aus Pimelinsaure wurde die trans-9-Oxo-decen-(2)-saure-(1) (10) und aus Korksaure die trans-10-Hydroxy-decen-(2)-saure-(1) (18) synthetisiert.
THE IRON-ACETOCARMINE METHOD OF FIXING AND STAINING CHROMOSOMES
A short description of this procedure was given in Vol. 55 of the American Naturalist, pp. 573â€”574. The method has now been used almost daily for five years, and certain improvements have suggested themselves. The solution can be prepared by mixing about equal volumes of glacial acetic acid and water. To this is added powdered carmine in excess. The liquid is then â€ ? just brought to boil, cooled, and decanted. To the red solution there are then added a few drops of a solution of ferric hydrate in 50 per cent. acetic acid, to act as a mordant. The amount of iron varies with different objects. Too much produces a precipitate in a short time. The more