PHYTOCHEMICAL AND ANTIMICROBIAL STUDIES OF EXTRACTS OF SOLANUM XANTHOCARPUM
Antibacterial activity of various parts (stem, leaf and fruits) of solvent extracts (Petroleum ether, alcohol and acetone) of Solanum xanthocarpum against Escherichia coil, Klebsiella of Solanum xanthocarpum showed high sensitivity to Escherichia coil & less sensitivity and resistance to Bacillus cereus. In control, no inhibitory zone was observed.
ANTIMICROBIAL STUDIES OF SOME SELECTED MEDICINAL PLANTS
Antimicrobial activities were detected in the 80% ethanolic extract of Achyranthes aspera, Ficus glomerata, Leucas aspera, Thespesia populnea and Zizyphus jujube against Escherichia coli, Klebsiella pneumoniae and salmonella typhi. The treatments resulted in the formation of various inhibitory zones, in contrast to the control where no inhibitory zone was observed.
Effect of 5alpha reduced androgens on sex accessory organs, initiation and maintenance of spermatogenesis in the rat.
The effect of several androgens on initiation and maintenance of spermatogeneSis was studied in newborn estrogen-blocked and in adult hypophysectomized rats. The steroid treatment inhibited testicular and body weight in all animals. Treatment of estrogen-blocked animals with androgens resulted in a stimulation of the growth of sex accessory organs, except in the case of androsterone. Initiation of spermatogenesis and its progression to mid pachytene stage (first wave) was observed in all steroid treated rats. In estrogen-blocked animals the first wave of spermatogenesis proceeded only to pachytene spermatocytes. Administration of testosterone propionate. dihydrotestosterone or 5a-androstanediol to these animals resulted in completion of meiosis and formation of spermatids up to Step 8 of spermiogenesis. Completion of meiosis was not observed in androsterone treated rats. In hypophysectomized animals all 5a-reduced androgens maintained spermatogenesis similar to testosterone.