Alkaloids from Lupinus argenteus var. stenophyllus.
TLC and GLC of an alkaloid extract of the aboveground portions of Lupinus argenteus Pursh. var. stenophyllus (Rydb.) Davis (Leguminosae) suggested the presence of sparteine, beta-isosparteine, delta5-dehydrolupanine, alpha-isolupanine, lupanine, thermopsine, and anagyrine. GLC-mass spectrometry confirmed these preliminary findings. Preparative TLC was used to isolate sparteine, and this alkaloid was further characterized by IR spectral analysis and derivatization.
Cactus alkaloids. XV. -Phenethylamine derivatives from Coryphantha macromris var. runyonii.
Eleven β-phenethylamine derivatives were isolated and identified from fresh-frozen specimens of Coryphantha macromeris var. runyonii (Br. and R.) L. Benson. Isolations were accomplished using preparative TLC, and identifications were based on chromato-graphic properties, IR and NMR spectra, and comparisons with authentic materials. The data provide initial documentation for: the occurrence of N-formylnormacromerine in nature; the first recorded detection of metanephrine and N-methylmetanephrine in the plant kingdom; the first occurrence of synephrine and N-methyltyramine in this cactus; confirmation of earlier GLC-mass spectral data on the presence of N-methyl-4-methoxy-β-phenethyl-amine, N-methyl-3,4-dimethoxy-β-phenethylamine, tyramine, and hordenine in the plant; and verification of previous reports on the isolation of macromerine and normacromerine.
Teratogenic compounds of Veratrum californicum as a function of plant part, stage, and site of growth☆
Abstract The level of the teratogen cyclopamine in Veratrum californicum varied considerably among plants from various collection sites. The variation was not correlated with differences in soil type, pH, soil nutrients, elevation, drainage, or sunlight. However, marked variation in both total alkaloid and percentage cyclopamine occurred as a function of stage of growth of the plant. The levels of both were highest in early growing season in the leaves, in midgrowing season in the stems and in late growing season in the root/rhizome system.