Flexible Follower Response of a Translating Cam with Four Different Profiles for Rise-Dwell-Fall-Dwell motion
The flexible follower response of a translating cam with four different profiles for rise-dwell-fall-dwell (RDFD) motion is investigated. The cycloidal displacement motion, the modified sinusoidal acceleration motion, the modified trapezoidal acceleration motion, and the 3-4-5 polynomial motion are employed to describe the rise and the fall motions of the follower and the associated four kinds of cam profiles are studied. Since the follower flexibility is considered, the contact point of the roller and the cam is an unknown. Two geometric constraints formulated to restrain the unknown position are substituted into Hamilton’s principle with Lagrange multipliers. Applying the assumed mode method, one can obtain the governing equations of motion as non-linear differential-algebraic equations. The equations are solved using Runge-Kutta method. Then, the responses of the flexible follower undergoing the four different motions are investigated in time domain and in frequency domain. Keywords—translating cam, flexible follower, rise-dwell-falldwell, response
The vibration of disc cam mechanism
Abstract In this paper, the longitudinal vibrations of a follower which is the linear active component of a cam mechanism is studied as if it has a constant cross section. The basic Bernoulli method is applied to solve the partial differential equation which is supplied by taking the viscous damping factor into consideration and by adding a new term. For the first time, in addition to the viscous damping, in this investigation, the internal damping term has been imposed to the motion of the follower. The resultant integration constants are determined by using the boundary conditions, and the eigen frequencies are calculated. As a result, two different families of eigen frequencies are remained. The results are formed as computer graphics to be easily understandable.
Analysis of molecular interactions in solid dosage forms; challenge to molecular pharmaceutics.
The molecular states of active pharmaceutical ingredients (APIs) in pharmaceutical dosage forms strongly affect the properties and quality of a drug. Various important fundamental physicochemical studies were reviewed from the standpoint of molecular pharmaceutics. Mechanochemical effects were evaluated in mixtures of APIs and pharmaceutical additives. Amorphization, complex formation and nanoparticle formation are observed after grinding process depending on the combination of APIs and pharmaceutical additives. Sealed-heating method and mesoporous materials have been used to investigate drug molecular interactions in dosage forms. Molecular states have been investigated using powder X-ray diffraction, thermal analysis, IR, solid state fluorometry, and NMR.