The analysis of research results concerning heat release rates of ship materials with regard to dynamic parameters of the research station
The analysis of research results concerning heat release rates of ship materials with regard to dynamic parameters of the research station Based on the results of author's research it was stated that significant differences between heat release rates measured according to ISO 5660-1 and FTP Code Part 5 (Res. A. 653 (16)) are not caused by measurement uncertainties. A basic factor determining the lack of correlation is treating the heat release rate in the category of static measurements in the normalized measurement methods. Taking into account dynamic parameters of the test station allowed the coincidence rate (reproducibility and correlation) of the results of heat release rates measured using different methods to be improved, without changing test stations and procedures. Author's research performed on 42 materials has revealed that the relative dynamic errors of the heat release rate measurements are significant (2%÷120%). The average value of these changes for the tested group of materials was equal to 39%.
Time delay correction for heat release rate data
A numerical scheme is presented to correct heat release rate measurements made with the Ohio State University rate of heat release apparatus for the effects of inherent time delays in the measurement system.
Semiautomated quantification of the fibrous tissue response to complex three-dimensional filamentous scaffolds using digital image analysis.
Fibrosis represents a relevant response to the implantation of biomaterials, which occurs not only at the tissue-material interface (fibrotic encapsulation) but also within the void fraction of complex three-dimensional (3D) biomaterial constructions (fibrotic ingrowth). Usual evaluation of the biocompatibility mostly depicts fibrosis at the interface of the biomaterial using semiquantitative scores. Here, the relations between encapsulation and infiltrating fibrotic growth are poorly represented. Virtual pathology and digital image analysis provide new strategies to assess fibrosis in a more differentiated way. In this study, we adopted a method previously used to quantify fibrosis in visceral organs to the quantification of fibrosis to 3D biomaterials. In a proof-of-concept study, we transferred the "Collagen Proportionate Area" (CPA) analysis from hepatology to the field of biomaterials. As one task of an experimental animal study, we used CPA analysis to quantify the fibrotic ingrowth into a filamentous scaffold after subcutaneous implantation. We were able to demonstrate that the application of the CPA analysis is well suited as an additional fibrosis evaluation strategy for new biomaterial constructions. The CPA method can contribute to a better understanding of the fibrotic interactions between 3D scaffolds and the host tissue responses.