From Mary Queen of Scots to the Scottish Capuchins: Scotland as a symbol of Protestant persecution in seventeenth-century Italian literature
Italian authors of the seventeenth century produced a myriad of historical texts, tragedies, oratorios and poems that dealt with the events of Mary Stuart's life. The tremendous outcry that her story caused all over Europe made Scotland one of the most powerful symbols of persecution of Catholics by Protestants. It was the image of Scotland as a land of martyrdom that possibly prompted the publication of two seventeenth-century Italian ‘biographies’, narrating the vicissitudes of the lives of two Scottish capuchins, and which ran to multiple editions down to the eighteenth century. This article explores the literary reception of Mary Queen of Scots in seventeenth-century Italian literature and, in so doing, opens up religious, cultural, and political implications, pointing to links between Scottish Catholic and European intellectuals, and the publishing networks of sympathetic Marian writing.
Polemic as Piety: Thomas Stapleton's Tres Thomae and Catholic Controversy in the 1580s
This article examines the triple biography of Thomas the Apostle, Thomas Becket and Thomas More, published by Thomas Stapleton in 1588 and generally regarded as a work of pious hagiography. By focusing on the circumstances in which the book was written and published, the article demonstrates its polemical significance at a time of rapid political change in Catholic/Protestant relations in both England and Europe. Conceived as a Catholic alternative to the history of the Christian past produced by Foxe, Stapleton's book also addressed contested issues within Catholicism: how to deal with the Elizabethan regime, and the status to be accorded to recent martyrs. In answering these questions, Stapleton's views reflect the complexity of Catholic thought at this time, and its fluidity in response to the shifting political circumstances of the late 1580s.
A peptide muscarinic toxin from the Green Mamba venom shows agonist-like action in an inhibitory avoidance learning task.
A peptide, muscarinic toxin 2 (MTX2), isolated from Dendroaspis angusticeps venom was previously shown to displace the specific binding of [3H]pirenzepine, a muscarinic M1 receptor ligand, from rat brain synaptosomal membranes. We have tested MTX2 for muscarinic agonist or antagonist actions in an inhibitory avoidance task in rats. Infusion of the muscarinic receptor antagonist scopolamine into the hippocampus of rats immediately after the training period produced amnesia, whereas the muscarinic agonist oxotremorine increased retention. When MTX2 was injected into the hippocampus of rats after the inhibitory avoidance task, it caused memory facilitation, which could be suppressed by the concomitant infusion of scopolamine. Hence, in this test, MTX2 showed muscarinic receptor agonist-like actions, which are probably mediated by the M1 subtype of muscarinic acetylcholine receptors.