‘The Rebellion From Below’ and the Origins of Early Zionist Christianity
ABSTRACT This article argues that Zionist Christianity emerged in South Africa out of the peasant revolt that occurred in the Boer Republics during and after the South African War. Using the experiences of early Zionist leaders Daniel Nkonyane and Engenas Lekganyane, the article demonstrates the continuity of their theology with the ideology of the ‘Rebellion From Below’ first described by Jeremy Krikler. The early Zionists, like their predecessors, were primarily interested in recreating a world based on communal politics and land ownership – a world without rents, landlords, or white supervision.
Zionism and Faith-Healing in Rhodesia: Aspects of African Independent Churches
This book by BU Emeritus Professor Marthinus L. Daneel is made available in OpenBU by permission of its author, who retains all rights to it.
Calyculins and Related Marine Natural Products as Serine-Threonine Protein Phosphatase PP1 and PP2A Inhibitors and Total Syntheses of Calyculin A, B, and C
Calyculins, highly cytotoxic polyketides, originally isolated from the marine sponge Discodermia calyx by Fusetani and co-workers, belong to the lithistid sponges group. These molecules have become interesting targets for cell biologists and synthetic organic chemists. The serine/threonine protein phosphatases play an essential role in the cellular signalling, metabolism, and cell cycle control. Calyculins express potent protein phosphatase 1 and 2A inhibitory activity, and have therefore become valuable tools for cellular biologists studying intracellular processes and their control by reversible phosphorylation. Calyculins might also play an important role in the development of several diseases such as cancer, neurodegenerative diseases, and type 2-diabetes mellitus. The fascinating structures of calyculins have inspired various groups of synthetic organic chemists to develop total syntheses of the most abundant calyculins A and C. However, with fifteen chiral centres, a cyano-capped tetraene unit, a phosphate-bearing spiroketal, an anti, anti, anti dipropionate segment, an α-chiral oxazole, and a trihydroxylated γ-amino acid, calyculins reach versatility that only few natural products can surpass, and truly challenge modern chemists’ asymmetric synthesis skills.