Establishment and Research Status of Bronchial Asthma Animal Model
Bronchial asthma is a chronic airway inflammatory disease participated by many cells and cellular elements,which continues to be a major health problem worldwide. Its mechanism include chronic airway inflammation,airway hyperresponsiveness,airway remolding,nervous system,allergic reaction and genetic problems,and they react with each other forming complex correlation. Establishing animial models is helpful to the research of the etiology and pathogenesis. Rodents are the most popular bronchial asthma models. Here is to make a review of recent asthma animal modeling research at home and aboard,to contribute to the further research about asthma.