Multiparticulates Drug Delivery Systems: A Review
Pharmaceutical research and development are increasingly focusing on delivery systems which enhance desirable therapeutic objectives while minimising side effects. Recent trends indicate that multiparticulate drug delivery systems are especially suitable for achieving controlled and delayed release oral formulations with low risk of dose dumping. These oral multiparticulate drug delivery systems offer biopharmaceutical advantages with respect to predictable and even distribution and transportation in the gastro intestinal tract. Pelletization is novel drug delivery system that converts fine powder particles into pellets and it is usefull in order to develop a site specific drug delivery system. There are different techniques in the preparation of pellets. Consequently, multiparticulate drug delivery systems provide tremendous opportunities for designing new controlled and delayed release oral formulations, thus extending the frontier of future pharmaceutical development.