Dysregulation of type I interferon responses in COVID 19
Infection with SARS CoV 2 can lead to excessive production of pro inflammatory cytokines, but the production of type I interferons, which are key antiviral mediators, is reportedly blunted. Here, we discuss how imbalanced interferon responses may contribute to the pathology of COVID 19. In this Comment, Michaela Gack and colleagues discuss how the dysregulation of type I interferon responses may contribute to COVID 19 pathology.
Nature Reviews Immunology