Ultrasound promoted, rapid, green, one pot synthesis of 2' aminobenzothiazolomethylnaphthols via a multi component reaction, catalyzed by heteropolyacid in aqueous media
Abstract A one pot, three component condensation reaction of 2 aminobenzothiazole, 2 naphthol and appropriate aldehydes catalyzed by heteropolyacid (HPA) in an aqueous medium afforded the Mannich adduct 2' aminobenzothiazolomethylnaphthols at 45 degC under ultrasound irradiation. This method provides several advantages such as simple work up procedure, short reaction time and high yields.