Activity of Tulsi leaves (Ocimum sanctum linn) in protecting gastric ulcer in rats by cold restrain method
Peptic ulcer is a chronic disease which impairs the quality of life and is associated with increased morbidity and mortality. Imbalance between the "aggressive" (acid, pepsin and H. pylori) and "defensive" factors (mucin, prostaglandin, bicarbonate, nitric oxide and growth factor) and presence of acid pepsin play an important role. Peptic ulcer disease is a worldwide problem and its treatment is essential.