Left atrial appendage occlusion using LAmbre Amulet and Watchman in atrial fibrillation.
BACKGROUND Left atrial appendage closure (LAAC) has been suggested as an alternative to anticoagulation in non valvular atrial fibrillation (AF) The present study aimed to compare a LAmbre LAA occluder system [Lifetech Scientific (Shenzhen) Co. Ltd. Shenzhen, China] with the most investigated Amulet (St. Jude Medical Inc. St. Paul, MN, USA) and Watchman (Boston Scientific, Plymouth, MN, USA) devices in terms of peri procedural and short term outcomes. METHODS This is a prospective observational study. RESULTS Overall, 140 patients (50 female, mean age 76.2+ 8.4 years) were consecutively enrolled. Mean CHA2DS2 VASc score was 3.8+ 1.5, and mean HAS BLED score was 3.9+ 1.1. Baseline clinical characteristics were comparable between the three groups (LAmbre, n=30; Amulet, n=74; Watchman, n=36) the LAmbre group had significantly more patients with complicated LAA morphology (p=0.006) The implant success rate was 100% in LAmbre, 99% in Amulet, and 100% in Watchman group (p=0.638) The number of device repositions was not significantly different between groups (0.7+ 1.1 in LAmbre, 1.0+ 2.0 in Amulet, and 1.4+ 1.8 in Watchman group, p=0.345) Fluoroscopic and procedural times were similar between groups. Major peri procedural adverse events did not differ between groups (0% vs. 0% vs. 2.8% p=0.233) Six months' follow up showed good device stability and patients' clinical condition in all groups. CONCLUSION LAmbre, Amulet, and Watchman exhibit remarkable implant success rate, low risk of peri procedural adverse events, and good clinical outcomes.
Journal of cardiology