Study on the effective toothpaste of adjunctive treatment of recurrent aphthous ulcer
Sodium azulene sulfonate, allantoin and tranexamic acid were used as active ingredients to prepare the effective toothpaste of adjunctive treatment of recurrent aphthous ulcer. The formulation and process of toothpaste were introduced. The safety of the product was evaluated.The function of the product was studied by bacteriostasis rate test and clinic test. The experimental results showed that the toothpaste was safe and non toxic. The killing rates for Streptococcus mutants, Staphylococcus aureus, Candida albicans and Escherichia coli were more than 99.98%and for Porphyromonas gingivalis was more than 98.14% There were significant effects on inhibiting dental plaque, reducing gingivitis and promoting RAU healing.