INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND BIO SCIENCE
Oxadiazole moiety and its various derivatives studied frequently in the past few decades and found potent in various pharmacological and pathological conditions. Oxadiazole is a versatile heterocyclic nucleus which has attracted a wide attention of the medicinal chemists in search for new therapeutic molecules. Oxadiazoles are five membered heterocyclic compounds with two nitrogen atoms and one oxygen atom. Oxadiazole possess a number of biological activities like anticancer, muscle relaxant, antimicrobial, anticonvulsant, antiviral, anti tubercular, anti amoebic, antiobesity, anti inflammatory activities etc. The present review describes the Chemistry, sources, synthetic review and pharmacological profile of 1,3,4 oxadiazole. The aim of the present paper is to review the available information on 1,3,4 oxadiazole.