Extra Adrenal Myelolipoma Containing Small Lymphocytic Lymphoma/Chronic Lymphocytic Leukemia: A Case Report and Review of the Literature
Myelolipoma is a benign tumor consisting of mature fat interspersed with hematopoietic elements resembling bone marrow. The vast majority occurs within the adrenal glands, but several cases of extra adrenal myelolipomas (EAMLs) have been reported. We report a case of a 64 year old male who presented with complaint of lower abdominal discomfort. CT scan of abdomen and pelvis showed a 6 cm x 5 cm, well circumscribed, predominantly fatty mass in the presacral region. Histological examination of the pelvic mass revealed a myelolipoma heavily infiltrated by small lymphoid cell aggregates with immunophenotypic features of small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) Review of the literature revealed that there is only one published report of SLL/CLL involving a myelolipoma, which was also an extra adrenal myelolipoma, and, therefore, our case is the second case of a SLL/CLL involving a myelolipoma that is an extra adrenal myelolipoma. Extra adrenal myelolipomas seem to the preferred myelolipomas for involvement by SLL/CLL.
Case reports in hematology