Programming Self Assembly of DNA Origami Honeycomb Two Dimensional Lattices and Plasmonic Metamaterials.
Scaffolded DNA origami has proven to be a versatile method for generating functional nanostructures with prescribed sub 100 nm shapes. Programming DNA origami tiles to form large scale 2D lattices that span hundreds of nanometers to the micrometer scale could provide an enabling platform for diverse applications ranging from metamaterials to surface based biophysical assays. Toward this end, here we design a family of hexagonal DNA origami tiles using computer aided design and demonstrate successful self assembly of micrometer scale 2D honeycomb lattices and tubes by controlling their geometric and mechanical properties including their interconnecting strands. Our results offer insight into programmed self assembly of low defect supra molecular DNA origami 2D lattices and tubes. In addition, we demonstrate that these DNA origami hexagon tiles and honeycomb lattices are versatile platforms for assembling optical metamaterials via programmable spatial arrangement of gold nanoparticles (AuNPs) into cluster and superlattice geometries.
Journal of the American Chemical Society