Dyslipidemia and its Correlation with Creatinine Clearence in Chronic Kidney Disease
Background: Dyslipidemia is recognized risk factors for progression of renal diseases. This altered lipid metabolism contribute to pathogenesis of cardiovascular disease as well as to the progression of renal disease. Aims: To measure the lipid profile in patients with Chronic kidney disease and to correlate HDL TGL levels with creatinine clearance. Materials and Methods: The biochemical parameters Blood urea Creatinine, Total Cholesterol, Triglycerides, HDL and LDL were measured in 50 cases 50 controls. Results and Conclusion: There is significantly higher serum TGL and VLDL levels and lower HDL levels in the cases than controls (p<0.05) There is higher TGL/HDL and LDL/HDL ratio in cases than controls (p<0.05).There is a serial increase in serum TGL and VLDL levels and a serial decrease in HDL levels with declining renal function (p<0.05)