6491207
Florida Wireless Implantable Recording Electrodes (FWIRE) for Brain Machine Interfaces
This paper reviews on-going efforts towards the development of the Florida wireless implantable recording electrodes (FWIRE). The FWIRE microsystem platform is a fully implantable flexible substrate microelectrode array that employs state-of-the-art integrate-and-fire (IF) signal representation and wireless interface circuitry for recording neural activity from behaving rodents. The modular nature of the implantable neural recording electrode allows future enhancements to be seamlessly added to improve functionality including but not limited to rechargeability through inductive coupling, custom microelectrode arrays, higher capacity batteries, and more advanced integrated circuit technologies. This paper concentrates on custom integrated circuits such as neural interfacing amplifiers, baseband signal processing, wireless data and power interfaces, and battery management system.
7156344
A New Architecture for Deriving Dynamic Brain-Machine Interfaces
Great potential exists for future Brain Machine Interfaces (BMIs) to help paralyzed patients, and others with motor disabilities, regain (artificial) motor control and autonomy. This paper describes a novel approach towards the development of new design architectures and research test-beds for advanced BMIs. It addresses a critical design challenge in deriving the functional mapping between the subject’s movement intent and actuated behavior. Currently, adaptive signal processing techniques are used to correlate neuronal modulation with known movements generated by the subject. However, with patients who are paralyzed, access to the individual’s movement is unavailable. Inspired by motor control research, this paper considers a predictive framework for BMI using multiple adaptive models trained with supervised or reinforcement learning in a closed-loop architecture that requires real-time feedback. Here, movement trajectories can be inferred and incrementally updated using instantaneous knowledge of the movement target and the individual’s current neuronal activation. In this framework, BMIs require a computing infrastructure capable of selectively executing multiple models on the basis of signals received by and/or provided to the brain in real time. Middleware currently under investigation to provide this data-driven dynamic capability is discussed.
43087664
Designing Ontological Agents: an Alternative to Improve Information Retrieval in Federated Digital Libraries
Search engines base their operation just in keywords management; some of them are ambiguous, consequently, a lot of irrelevant results are produced. To take into account the meaning of keywords, we describe the architecture of a multi-agent system in charged of information retrieval tasks in digital libraries. The main components are termed ontological agents. They are software entities that make use of ontologies to expand queries and to avoid as much ambiguity as possible of keywords. Ontologies are also used to identify relevant sources of information. The design of these agents is based on Gaia methodology.
23700051
Fourth-phase digital libraries: pacing, linking, annotating and citing in multimedia collections
We discuss the implications of the use of current multimedia collections and posit that it is possible to build what we term fourth-phase digital libraries (4PDLs). In 4PDLs users can take advantage of both the powerful audiovisual channels and the proven practices developed for media such as text. We demonstrate how various technologies can be integrated to produce a 4PDL.
39021049
Current status of the SWISS-2DPAGE database
The SWISS-2DPAGE database (http: //www.expasy.ch/ch2d/ch2d-top.html ) consists of two-dimensional polyacrylamide gel electrophoresis images, as well as textual descriptions of the proteins that have been identified on them. The current release contains 15 reference maps from human biological samples, as well as from Saccharomyces cerevisiae , Escherichia coli and Dictyostelium discoideum origin. These reference maps have 2088 identified spots, corresponding to 410 separate protein entries in the database, in addition to virtual entries for each SWISS-PROT sequence.
7626983
Intelligent Remote Monitoring
Intelligent monitoring facilities are of paramount importance in both service and network management as they provide the capability to monitor quality of service and utilisation parameters and notify degradations so that corrective action can be taken. By intelligent, we refer to the capability of performing the monitoring tasks in a way that has the smallest possible impact on the managed network, facilitates the observation and summarisation of information according to a number of criteria and, in its most advanced form, permits the specification of these criteria dynamically to suit the particular policy in hand. The OSI management metric monitoring and summarisation management functions provide models that only partially satisfy the above requirements. This paper describes our extensions to the proposed models to support further capabilities, with the intention to eventually lead to fully dynamically defined monitoring policies. The concept of distributing intelligence is also discussed, including the consideration of security issues and the applicability of the model in CORBA-based environments.
1924989
MiBiblio: personal spaces in a digital library universe
This paper describes MiBiblio, a highly personalizable interface to large collections in digital libraries. MiBiblio allows users to create virtual places we term personal spaces. As users find useful items in the repositories, they organize these items and keep them handy in their personal spaces for future use. Personal spaces may also be updated by user agents.