28307729
Introduction to OGSA-DAI Services
In today's large collaborative environments, potentially composed of multiple distinct organisations, uniform controlled access to data has become a key requirement if these organisations are to work together as Virtual Organisations. We refer to such an integrated set of data resources as a virtual data warehouse. The Open Grid Services Architecture – Data Access and Integration (OGSA-DAI) project was established to produce a common middleware solution, aligned with the Global Grid Forum's (GGF) OGSA vision [OGSA] to allow uniform access to data resources using a service based architecture. In this paper the service infrastructure provided by OGSA-DAI is presented providing a snapshot of its current state, in an evolutionary process, which is attempting to build infrastructure to allow easy integration and access to distributed data using grids or web services. More information about OGSA-DAI is available from the project web site: www.ogsadai.org.
911042
The design and implementation of Grid database services in OGSA-DAI
1EPCC, University of Edinburgh, James Clerk Maxwell Building, Mayfield Road, Edinburgh EH9 3JZ, U.K. 2National e-Science Centre, 15 South College Street, Edinburgh EH8 9AA, U.K. 3IBM United Kingdom Ltd, Hursley Park, Winchester S021 2JN, U.K. 4Department of Computer Science, University of Manchester, Oxford Road, Manchester M13 9PL, U.K. 5Oracle UK Ltd, Thames Valley Park, Reading RG6 1RA, U.K. 6School of Computing Science, University of Newcastle, Newcastle-upon-Tyne NE1 7RU, U.K.
14699876
Automated Schematic Mapping for MobileGIS: Technical developments and Human Factors requirements
This paper looks at how human factors requirements can be considered in the context of graphic conflict reduction for mobile GIS applications. Currently this reduction is achieved by using schematic mapping techniques. With the advent of high-end miniature technology as well as digital geographic data products like OSMasterMap and OSCAR, it is essential to devise proper methodologies for map generalization specifically tailored for MobileGIS applications. This paper is concerned with the problem of producing schematic maps suitable for rendering on mobile display devices (e.g. PDAs). The application of schematic mapping can be thought of as a data reduction technique for large scale datasets to make it suitable for rendering in mobile applications. These techniques have been based on computation and have not incorporated any understanding of how the simplification affects the ease of use of the maps. It is therefore desirable to devise suitable generalization techniques incorporating human factors considerations for generating schematic maps from large scale datasets for display on small display devices to be used for MobileGIS applications
5845276
Immunofluorescence imaging as a tool for studying the pharmacokinetics of a human monoclonal single chain fragment antibody
We have used immunofluorescence imaging to study binding of a monoclonal antibody fragment to subcutaneously implanted human melanoma cells in nude mice. The data acquired using this nontraditional approach was then analyzed using standard pharmacokinetic methods to produce estimates of k/sub e/ (0.06 h/sup -1/), t/sub 1/2/ (16 h), mean residency time (23.4 h) and percent exposure of the antibody to the tumor (40%). To our knowledge this is the first time standard pharmacokinetic analyzes have been conducted on immunofluorescence imaging data. The combination of this novel imaging technique and standard pharmacokinetic analytical methods should prove to be a useful tool for comparing the properties of antibody fragments in animal models.
31777274
Automated Schematization for Web Service Applications
For the purposes of this paper, a schematic map is a diagrammatic representation based on linear abstractions of networks. With the advent of technologies for web-based delivery of geospatial services it is essential to develop map generalization applications tailored for the same. This paper is concerned with the problem of producing automated schematic maps for web map applications. The paper looks at how previous solutions to the spatial conflict reduction can be adapted and applied to production of automated schematic maps for web services.