14752166
Mapping ventricular changes related to dementia and mild cognitive impairment in a large community-based cohort
We present a fully-automated technique for visualizing localized cerebral ventricle shape differences between large clinical subject groups who have received a magnetic resonance (MR) image scan. The technique combines a robust, automated technique for ventricular segmentation with a 3D surface-based radial thickness mapping approach that allows spatially-localized statistical tests of relative shape differences between clinical groups. The technique is used to analyze localized ventricular expansion in Alzheimer's disease (AD) and mild cognitive impairment (MCI) in a large cohort of community-dwelling elderly individuals (N=339). The resulting maps are the first to chart localized ventricular dilation in a cohort of this size. Besides showing patterns of ventricular expansion that may be consistent with the spatial progression of AD-related pathology, the maps reveal new information about localized ventricular atrophy that may have been overlooked to date. A detailed understanding of spatial atrophy patterns may be useful for early disease detection or for patient monitoring in drug trials
122978488
Representation and matching of articulated shapes
We consider the problem of localizing the articulated and deformable shape of a walking person in a single view. We represent the non-rigid 2D body contour by a Bayesian graphical model whose nodes correspond to point positions along the contour. The deformability of the model is constrained by learned priors corresponding to two basic mechanisms: local non-rigid deformation, and rotation motion of the joints. Four types of image cues are combined to relate the model configuration to the observed image, including edge gradient map, foreground/background mask, skin color mask, and appearance consistency constraints. The constructed Bayes network is sparse and chain-like, enabling efficient spatial inference through sequential Monte Carlo sampling methods. We evaluate the performance of the model on images taken in cluttered, outdoor scenes. The utility of each image cue is also empirically explored.
5262963
Texture replacement in real images
Texture replacement in real images has many applications, such as interior design, digital movie making and computer graphics. The goal is to replace some specified texture patterns in an image while preserving lighting effects, shadows and occlusions. To achieve convincing replacement results we have to detect texture patterns and estimate the lighting map from a given image. Near regular planar texture patterns are considered in this paper. Given a sample texture patch, a standard tile is computed. Candidate texture regions are determined by mutual information between the standard tile and each image patch. Regions with high mutual information scores are used to estimate the admissible lighting distributions, which is represented by cached statistics. Spatial lighting change constraints are represented by a Markov random field model. Maximum a posteriori estimation of the texture segmentation and lighting map is solved in a stochastic annealing fashion, namely, the Markov chain Monte Carlo method. Visually satisfactory result is achieved using this statistical sampling model.
14419032
Content-based 3D neuroradiologic image retrieval: preliminary results
A content-based 3D neuroradiologic image retrieval system is being developed at the Robotics Institute of CMU. The special characteristics of this system include: directly dealing with multimodal 3D images (MR/CT); image similarity based on anatomical structures of the human brain; and combining both visual and collateral information for indexing and retrieval. A testbed has been implemented for using detected salient visual features for indexing and retrieving 3D images.
1966938
Robust midsagittal plane extraction from normal and pathological 3-D neuroradiology images
This paper focuses on extracting the ideal midsagittal plane (iMSP) from three-dimensional (3-D) normal and pathological neuroimages. The main challenges in this work are the structural asymmetry that may exist in pathological brains, and the anisotropic, unevenly sampled image data that is common in clinical practice. We present an edge-based, cross-correlation approach that decomposes the plane fitting problem into discovery of two-dimensional symmetry axes on each slice, followed by a robust estimation of plane parameters. The algorithm's tolerance to brain asymmetries, input image offsets and image noise is quantitatively evaluated. We find that the algorithm can extract the iMSP from input 3-D images with 1) large asymmetrical lesions; 2) arbitrary initial rotation offsets; 3) low signal-to-noise ratio or high bias field. The iMSP algorithm is compared with an approach based on maximization of mutual information registration, and is found to exhibit superior performance under adverse conditions. Finally, no statistically significant difference is found between the midsagittal plane computed by the iMSP algorithm and that estimated by two trained neuroradiologists.
5064803
Body Localization in Still Images Using Hierarchical Models and Hybrid Search
We present a 3-level hierarchical model for localizing human bodies in still images from arbitrary viewpoints. We first fit a simple tree-structured model defined on a small landmark set along the body contours by Dynamic Programming (DP). The output is a series of proposal maps that encode the probabilities of partial body configurations. Next, we fit a mixture of view-dependent models by Sequential Monte Carlo (SMC), which handles self-occlusion, anthropometric constraints, and large viewpoint changes. DP and SMC are designed to search in opposite directions such that the DP proposals are utilized effectively to initialize and guide the SMC inference. This hybrid strategy of combining deterministic and stochastic search ensures both the robustness and efficiency of DP, and the accuracy of SMC. Finally, we fit an expanded mixture model with increased landmark density through local optimization. The model hierarchy is trained on a large number of gait images. Extensive tests on cluttered images with varying poses including walking, dancing and various types of sports activities demonstrate the feasibility of the proposed approach.
12839905
Context sensitive vocabulary and its application in protein secondary structure prediction
Protein secondary structure prediction is an important step towards understanding the relation between protein sequence and structure. However, most current prediction methods use features difficult for biologists to interpret. In this paper, we present a new method that applies information retrieval techniques to solve the problem:we extract a context sensitive biological vocabulary for protein sequences and apply text classification methods to predict protein secondary structure. Experimental results show that our method performs comparably to the state-of-art methods. Furthermore, the context sensitive vocabularies can serve as a useful tool to discover meaningful regular expression patterns for protein structures.
8093965
A feature-based approach for individualized human head modeling
The human head is a significant part of the human body, with which we can recognize individuals from a vast universe of populations. Since the early 1970s, considerable effort has been devoted to computeraided modeling of human head for applications varied from realistic effect in computer graphics to custom model generation in modern manufacturing industries. However, realistic head modeling is still a challenge and continues to fascinate computer graphics researchers. The greatest difficulties in human head modeling result from the extremely complex geometric form of the human head. To generate realistic individualized models, most proposed head modeling techniques use the common approach of deforming a generic model into an individualized one, based on individual head information. There are various sources to obtain individual information, e.g., anthropometric data, range data and 2D pictures. Given the individual information, the quality of the resulting individualized model depends on the quality of the generic model and the deformation technique used. In our study, we observe that the mathematical form in which the generic model is represented strongly determines the deformation effect and, thus, determines the quality of the resulting individualized models. During the past few years, the multiresolution modeling technique has been demonstrated to be a powerful tool for highly detailed sculptured object modeling. In our work, we adopt the multiresolution technique for generic head modeling and propose a feature-based deformation technique. We show that using our technique we can generate highly realistic individualized head models with speed and efficiency. We also demonstrate that our proposed technique can result in great efficiency for a wide range of downstream applications.
13208870
An Evolutionary Approach to Adaptive Model-Building
Learning an input-output mapping from a set of examples can be regarded as a problem of model-building. From this point of view, by a hierarchical representation scheme for models, an evolutionary computational approach to model-building problems is proposed in this paper, which is based on the ideas from the evolution programs and the genetic programmings. The computer experiments indicate that it is surprisingly effective in searching the optimal model for model-building problems.
232914
Active and real-time functionalities for electronic brokerage design
In this position paper, we discuss an architecture for developing next generation electronic brokerages using active and real-time functionalities. These electronic brokerages support timeliness requirements and allow users to express complex preferences. User preferences can be conveniently captured as event-condition-action (ECA) rules. The design allows pro-active monitoring of user preferences and execution of actions in a timely manner. A proof-of-concept prototype is implemented using Java in the context of online trading. The prototype consists of three major components: rule validator, active rule manager and event monitor.
18353926
Inverse validation for accurate range image registration with structured data
Automatic range image registration is a fundamental yet extremely difficult problem in machine vision. In this paper, we extend a promising registration algorithm, the geometric iterative closest point (GICP), for structured image data. The extended algorithm is based on a relaxation method combining the motion estimation results from the possible correspondences established by the GICP algorithm and those that are further evaluated by an inverse validation procedure. A comparative study based on real images has shown that the extended algorithm is more accurate and robust than the original algorithm.