17112567
/spl delta/-clusters: capturing subspace correlation in a large data set
Clustering has been an active research area of great practical importance for recent years. Most previous clustering models have focused on grouping objects with similar values on a (sub)set of dimensions (e.g., subspace cluster) and assumed that every object has an associated value on every dimension (e.g., bicluster). These existing cluster models may not always be adequate in capturing coherence exhibited among objects. Strong coherence may still exist among a set of objects (on a subset of attributes) even if they take quite different values on each attribute and the attribute values are not fully specified. This is very common in many applications including bio-informatics analysis as well as collaborative filtering analysis, where the data may be incomplete and subject to biases. In bio-informatics, a bicluster model has recently been proposed to capture coherence among a subset of the attributes. We introduce a more general model, referred to as the /spl delta/-cluster model, to capture coherence exhibited by a subset of objects on a subset of attributes, while allowing absent attribute values. A move-based algorithm (FLOC) is devised to efficiently produce a near-optimal clustering results. The /spl delta/-cluster model takes the bicluster model as a special case, where the FLOC algorithm performs far superior to the bicluster algorithm. We demonstrate the correctness and efficiency of the /spl delta/-cluster model and the FLOC algorithm on a number of real and synthetic data sets.
5788516
Efficient genome ancestry inference in complex pedigrees with inbreeding
Motivation: High-density SNP data of model animal resources provides opportunities for fine-resolution genetic variation studies. These genetic resources are generated through a variety of breeding schemes that involve multiple generations of matings derived from a set of founder animals. In this article, we investigate the problem of inferring the most probable ancestry of resulting genotypes, given a set of founder genotypes. Due to computational difficulty, existing methods either handle only small pedigree data or disregard the pedigree structure. However, large pedigrees of model animal resources often contain repetitive substructures that can be utilized in accelerating computation. Results: We present an accurate and efficient method that can accept complex pedigrees with inbreeding in inferring genome ancestry. Inbreeding is a commonly used process in generating genetically diverse and reproducible animals. It is often carried out for many generations and can account for most of the computational complexity in real-world model animal pedigrees. Our method builds a hidden Markov model that derives the ancestry probabilities through inbreeding process without explicit modeling in every generation. The ancestry inference is accurate and fast, independent of the number of generations, for model animal resources such as the Collaborative Cross (CC). Experiments on both simulated and real CC data demonstrate that our method offers comparable accuracy to those methods that build an explicit model of the entire pedigree, but much better scalability with respect to the pedigree size. Contact: weiwang@cs.unc.edu
2548187
Mining asynchronous periodic patterns in time series data
Periodicy detection in time series data is a challenging problem of great importance in many applications. Most previous work focused on mining synchronous periodic patterns and did not recognize the misaligned presence of a pattern due to the intervention of random noise. In this paper, we propose a more flexible model of asynchronous periodic pattern that may be present only within a subsequence and whose occurrences may be shifted due to disturbance. Two parameters min rep and max dis are employed to specify the minimum number of repetitions that is required within each segment of nondisrupted pattern occurrences and the maximum allowed disturbance between any two successive valid segments. Upon satisfying these two requirements, the longest valid subsequence of a pattern is returned. A two-phase algorithm is devised to first generate potential periods by distance-based pruning followed by an iterative procedure to derive and validate candidate patterns and locate the longest valid subsequence. We also show that this algorithm cannot only provide linear time complexity with respect to the length of the sequence but also achieve space
7408751
Quantitative Association Analysis Using Tree Hierarchies
Association analysis arises in many important applications such as bioinformatics and business intelligence. Given a large collection of measurements over a set of samples, association analysis aims to find dependencies of target variables to subsets of measurements. Most previous algorithms adopt a two-stage approach; they first group samples based on the similarity in the subset of measurements, and then they examine the association between these groups and the specified target variables without considering the inter-group similarities or alternative groupings. This can lead to cases where the strength of association depends significantly on arbitrary clustering choices. In this paper, we propose a tree-based method for quantitative association analysis. Tree hierarchies derived from sample similarities represent many possible sample groupings. They also provide a natural way to incorporate domain knowledge such as ontologies and to identify and remove outliers. Given a tree hierarchy, our association analysis evaluates all possible groupings and selects the one with strongest association to the target variable. We introduce an efficient algorithm, TreeQA, to systematically explore the search-space of all possible groupings in a set of input trees, with integrated permutation tests. Experimental results show that TreeQA is able to handlelarge-scale association analysis very efficiently and is more effective and robust in association analysis than previous methods.
62615149
Mining Asynchronous Periodic Patterns in Time Series Data
Periodicy detection in time series data is a challenging problem of great importance in many applications. Most previous work focused on mining synchronous periodic patterns and did not recognize the misaligned presence of a pattern due to the intervention of random noise. In this paper, we propose a more flexible model of asynchronous periodic pattern that may be present only within a subsequence and whose occurrences may be shifted due to disturbance. Two parameters min/spl I.bar/rep and max/spl I.bar/dis are employed to specify the minimum number of repetitions that is required within each segment of nondisrupted pattern occurrences and the maximum allowed disturbance between any two successive valid segments. Upon satisfying these two requirements, the longest valid subsequence of a pattern is returned. A two-phase algorithm is devised to first generate potential periods by distance-based pruning followed by an iterative procedure to derive and validate candidate patterns and locate the longest valid subsequence. We also show that this algorithm cannot only provide linear time complexity with respect to the length of the sequence but also achieve space efficiency.
14969897
Dynamic adaptive file management in a local area network
In light of advances in processor and networking technology, especially the emergence of network attached disks, the traditional client-server architecture of file systems has become suboptimal for many computation/data intensive applications. We introduce a revised architecture for file management employing network attached storage: the dynamic file server environment (Dynamo). Dynamo introduces two main architectural innovations: to provide high scalability, the file management functions are mainly performed cooperatively by the clients in the system. Furthermore, data is transferred directly to the client's cache from network-attached disks, thus avoiding copies from a disk to the server buffer and then over the network to the client. Secondly, Dynamo uses a cooperative cache management which employs a decentralized lottery-based page replacement strategy. We show via performance benchmarks run on the Dynamo system and simulation results how this architecture increases the system's adaptability, scalability and cost performance.
2266606
Space-efficient Relative Error Order Sketch over Data Streams
We consider the problem of continuously maintaining order sketches over data streams with a relative rank error guarantee ∊. Novel space-efficient and one-scan randomised techniques are developed. Our first randomised algorithm can guarantee such a relative error precision ∊ with confidence 1 - \delta using O( 1\_ \in \frac{1} {2}2 log 1d log ∊^2N) space, where N is the number of data elements seen so far in a data stream. Then, a new one-scan space compression technique is developed. Combined with the first randomised algorithm, the one-scan space compression technique yields another one-scan randomised algorithm that guarantees the space requirement is O( 1\frac{1} { \in } log(1\frac{1}{ \in } log 1\begin{gathered} \frac{1}{\delta } \hfill \\ \hfill \\ \end{gathered} )\frac{{\log ^{2 + \alpha } \in N}} {{1 - 1/2^\alpha }} (for\alpha \gt 0) on average while the worst case space remains O( \frac{1}{{ \in ^2 }}\log \frac{1} {\delta }\log \in ^2 N). These results are immediately applicable to approximately computing quantiles over data streams with a relative error guarantee \in and significantly improve the previous best space bound O( \frac{1} {{ \in ^3 }}\log \frac{1}{\delta }\log N). Our extensive experiment results demonstrate that both techniques can support an on-line computation against high speed data streams.
14135377
Utility-based anonymization using local recoding
Privacy becomes a more and more serious concern in applications involving microdata. Recently, efficient anonymization has attracted much research work. Most of the previous methods use global recoding, which maps the domains of the quasi-identifier attributes to generalized or changed values. However, global recoding may not always achieve effective anonymization in terms of discernability and query answering accuracy using the anonymized data. Moreover, anonymized data is often for analysis. As well accepted in many analytical applications, different attributes in a data set may have different utility in the analysis. The utility of attributes has not been considered in the previous methods.In this paper, we study the problem of utility-based anonymization. First, we propose a simple framework to specify utility of attributes. The framework covers both numeric and categorical data. Second, we develop two simple yet efficient heuristic local recoding methods for utility-based anonymization. Our extensive performance study using both real data sets and synthetic data sets shows that our methods outperform the state-of-the-art multidimensional global recoding methods in both discernability and query answering accuracy. Furthermore, our utility-based method can boost the quality of analysis using the anonymized data.
20468001
Adaptive backstepping control of uncertain systems with unknown input time-delay
In this paper, we establish the robustness of adaptive controllers designed using the standard backstepping technique with respect to unmodeled dynamics involving unknown input time delay. While noting that some results on robust stabilization of non-minimum phase systems using the backstepping technique are available, we realize that the standard adaptive backstepping technique has only been shown applicable to unknown minimum phase systems. Another significance of our result is to enable the class of systems stablizable by adaptive backstepping controllers to cross the boundary of minimum phase systems, since systems with input time delay belong to non-minimum phase systems. Moreover, the L"2 and L"~ norms of the system output are also established as functions of design parameters. This implies that the transient system performance can be adjusted by choosing suitable design parameters.
7316344
CLINCH: Clustering Incomplete High-Dimensional Data for Data Mining Application
Clustering is a common technique in data mining to discover hidden patterns from massive datasets. With the development of privacy-maintaining data mining application, clustering incomplete high-dimensional data has becoming more and more useful. Motivated by these limits, we develop a novel algorithm CLINCH, which could produce fine clusters on incomplete high-dimensional data space. To handle missing attributes, CLINCH employs a prediction method that can be more precise than traditional techniques. On the other hand, we also introduce an efficient way in which dimensions are processed one by one to attack the “curse of dimensionality”. Experiments show that our algorithm not only outperforms many existing high-dimensional clustering algorithms in scalability and efficiency, but also produces precise results.
6226035
Online and adaptive anomaly Detection: detecting intrusions in unlabelled audit data streams
Disclosed is a method of lowering the prolactin level in the blood or serum of a person which method comprises administering a therapeutically effective amount of 2-amino-6-allyl-5,6,7,8-tetrahydro-4H-thiazolo-[5,4-d]azepine or a non-toxic, pharmaceutically acceptable acid addition salt thereof.