Marfan syndrome and the thumb sign.
A 74-year-old woman presented with congestive heart failure exacerbation. She was known to have moderate–to-severe aortic regurgitation and echocardiogram exam demonstrated ascending aortic aneurysm of 4.6 cm diameter on her recent hospitalization, 1 month ago. The patient's appearance was suggestive for Marfan syndrome, and complete physical examination, in addition to the known aortic root disease, further strengthened …