Autoimmunity in women with sex chromosome aneuploidy and in their parents compared to controls.
The incidence of thyroid and gastric antibodies in patients with clinical and cytogenetic features of gonadal dysgenesis, in doubly chromatin positive women and in the parents of patients with gonadal dysgenesis was not found to be significantly higher than in controls matched for age. 
 
The incidence of antibodies appeared to be appreciably higher in mosaics and in mosaics whose sex chromosome complement included an isochromosome of the long arm of the X. Failure to establish the significance of these raised incidences may be due to inadequate numbers. 
 
The discrepancy between the findings in this series and in previously reported series is discussed.