IgG4 RELATED OPHTHALMIC DISEASE: AN OVERVIEW
IgG4-related disease is a fibro-inflammatory condition with tendency to form tumors with inflammatory infiltrate and elevation of IgG4 level in serum, which may affect virtually every organ and tissue. It may present as dacryoadenitis, myositis, hypophysitis or pachymeningitis causing cranial neuropathies. The diagnosis of IgG4-related disease is based on a typical clinical scenario, supportive laboratory data,radiological findings and distinct histopathological and immuno-histochemical features. Corticosteroid followed by long-term immunosuppressive therapy is the most commonly attempted treatment.