The Meinicke Klarungs Reaction: The Development of an Improved Test
1. By the introduction of certain radical modifications, an improved flocculation test, based on the Meinicke-Klarungs reaction, has been described.

2. Simplification of the serum-reacting, colloid-electrolytic system by reducing the number of elements operating, e.g., the elimination of free acids from the balsam of Tolu resulting in the abolition of the use of sodium carbonate, has made it possible to effect a better control of the factors on which depend sensitivity and specificity.

3. A method of standardizing the antigen has been formulated which is independent of the use of syphilitic and non-syphilitic sera.

4. A method of absorption of free acids from natural Tolu balsam by light magnesium carbonate has been described.

5. The recommended standard of purity of the solvents used in the preparation of the heart extract is regarded as essential in obtaining a uniform product.