Electrochemical asymmetric reduction of prochiral carbonyl compounds, oximes, and a gem-dihalide on a poly-L-valine-coated graphite electrode.
The electrochemical asymmetric reduction of prochiral carbonyl compounds, oximes, and a gem-dihalide was examined by using a poly-L-valine-coated graphite electrode. The highest asymmetric yield (16.6%) was obtained in the reduction of 1,1-dibromo-2,2-diphenylcyclopropane to the corresponding monobromocyclopropane.