Search for new antifungal compounds from higher plants
The increasing occumnce of opportunistic systemic mycoses associated with the use of immunosuppressive drugs and AIDS has led to new efforts in the search for novel antifungal compounds. At the same time, there is continuing interest in the discovery of antifungal agents which are effective against plant pathogenic fungi. Since the plant kingdom provides a useful source of lead compounds of novel structure, a wide-scale investigation of species from the tropics has been undertaken. TLC bioautography allows the screening of plant material and subsequent bioassay-guided fractionation and isolation.