MEASUREMENT AND CORRELATION OF TAXOL SOLUBILITY IN METHANOL,ETHANOL AND METHANOL-WATER SYSTEMS
Taxol is a unique antitumor drug that appears to exert its activity as a result of interference with microtubular structure and function. The Taxol solubility of in methanol, ethanol and methanol-water was measured by the equilibrium method in this paper. The data obtained were correlated by the regress equation and ANN model. The results showed that the both were in excellent agreement with the experimental data and the ANN model was more convenient than the regress equation.