Review of signal transduction channels for active oxygen to induce the production of interleukin-6 originating from muscles during exercising
The authors gave an overview of such issues as the mechanism for active oxygen to induce the production of interleukin-6(IL-6) originating from muscles during exercising.IL-6 is a type of cytokine that changes very significantly in the process of exercising;its changing magnitude is closely related to exercise time and exercise intensity.Via their study the authors revealed the following findings: IL-6 produced during exercising originates primarily from contracting skeletal muscle;free radicals produced by skeletal muscle in the process of exercising,especially active oxygen,are a major cause for inducing the production of IL-6 during exercising.