Synthesis of perhydro-1,5-dioxa-3-azepine derivatives
N-Acyl-, N-alkoxycarbonyl-, and N-benzenesulfonylperhydro-1,5-dioxa-3-azepine derivatives were obtained in 9–20% yields by condensation of ethylene glycol with unsubstituted amides, urethanes, and formaldehyde in refluxing xylene in the presence of a catalyst (concentrated HCl).