Diels-Alder reaction of chiral acrylamide and a convenient synthesis of optically pure methyl (3R, 4R, 6R)-bicyclo[2.2.1]heptene-4-carboxylate
Asymmetric Diels–Alder reaction of the chiral acrylamide 1 proceeds highly diastereoselectively and methanolysis of the adduct 2 gives the optically pure (3R, 4R, 6R)-bicyclo [2. 2. 1]heptene-4-carboxylate.