Investigation of DNA sequencing droplet trajectory observation and analysis
Abstract In this study, DNA sequencing droplet trajectories are observed and analyzed using an application-specific integrated circuit system and a micro-electromechanical system structure jetting chip. We investigate a droplet jetting technique and apply it to biomedical test chips. This use of a sprayed chip structure can reduce sequencing time by two-thirds compared with traditional methods. The structure is a three-dimensional, multi-channel drive system that can control droplets more precisely. The circuit's input control signal was generated and placed on a chip based on the quantitative design of liquid droplets. Delay time and frequency were used to set the LED light sources. In this study, we would use frequencies of 4 kHz, 8 kHz, and 12 kHz combined with two groups of different orifices and frequencies for ink droplet outlet velocity.