Quantiative analysis of sodium cyclamate in food by liquid chromatograph-mass spectrometry
A liquid chromatograph-mass spectrometric method for the determination of sodium cyclamate in food had been established.We studied the effects of differert solvents and found that the recovery was better than others if extracted with ethyl acetate and methyl cyanide.The seperation was carried out on a C18 analytical column with a liner gradiert elution of methyl(A)-solution of 0.02 mol/L ammonium acetate.The linear range was 0.02～0.3 μg/mL and r was 0.9994.The recoveries were in a range of 70.5%～88.2% and the relative standard deviations were less than 6.0%.This method not only was accurate and rapid,but also had preferable reproducivity.It could apply to the analysis of many kinds of flavoring and food such as sugar,mianshaowan,and so on.So it met the needs of practical analysis.