Preparation of new polymeric active coatings for vascular applications, based on biocompatible acrylic systems with anti-inflammatory components
Data on the preparation of hydrophilic polymeric systems based on copolymers of 2-hydroxyethylmethacrylate H, with new acrylic derivatives of 4-methoxyphenylacetic acid or Ibuprofen (drugs widely used as analgesic and non-steroidic anti-inflammatory agents) are presented. The copolymer systems prepared with 5-20% of the pharmacologically active acrylic derivative form hydrophilic films when a solution of the prescribed concentration is applied as a coating of biomaterials used for the preparation of vascular implantss like knitted or woven meshes of Dacron or small-diameter vascular grafts of Goretex