Determination of L-Phenylalanine with a Molecularly Imprinted Electrochemiluminescence Sensor
A novel ECL-MIP sensor for the determination of L-phenylalanine was reported.The sensor was prepared by the electrodeposition of the molecular imprinting membrance by sol-gel method onto the Ru(bpy)2+3 modified glassy carbon electrode.The electrochemical and electrochemiluminescence behavior of the sensor was investigated.The proposed sensor displayed high sensitivity and excellent selectivity for the target molecule L-phenylalanine.Under the optimum conditions,a linear response was observed with the concentrations of L-phenylalanine from 1.0×10#11mol/L to 1.0×10#8mol/L and the detection limit was 3.1×10#12mol/L.The sensor was successfully applied to the determination of L-phenylalanine in urine samples with the recoveries from 94.8% to 110.6%.