Synthesis and stereochemistry of 5-substituted quinuclidine-2-carboxylic acids with semicyclic double bonds
Esters of 5-methylene- and 5-ethylidenequinuclidine-2-carboxylic acid were synthesized using the Wittig reaction. Using NMR spectra, the stereochemistry of the 5-substituted quinuclidine-2-carboxylic acids with semicyclic double bonds was studied.