The Rsearch In the Pharmic Effect of Chinese Traditional Medicine Sanlongdan
Objective to discuss the mechanism of controlling tumour about Chinese traditional Sanlongdan,so that we can provide academic foundation in using medicine in clinic.Methods 1 The experiment in body: the knubbly cell W256 was inoculated in left and front oxter of rats,the dose was 0.3ml per rat and take medicine next day. Saline,Cyclophosphamide and different dose Sanlongdan were used respectively in negative comparison group, electropositive comparison group and Chinese medicine group.2 Experiment out of body: we diluted Sanlongdan by rato 1:10,1:20,1:40,1:80,1:160,1:320,1:640,1:1280.then it was inoculated on HEL and NKM in lacunaris culture board.Observe the pathological changes of cell,and count the exponent of restraining tumour.3 The infection on MDA and SOD of Sanlongdan:40 mouse were divided into 4 groups,using the same way of taking medicine as the experiment in body.30 days later,every mouse was taken blood by extirpating eyeball.We measure the drgee of SOD and MDA.Results Chinese traditional medicine Sanlongdan can effectly restrain W256 tumour.When it's degree is 1:80,it has the most effective action and at the same time it can also improve obviousely the activement of SOD,reduce the metabolize outcome of MDA.Conclusion Chinese traditional medicine Sanlongdan can affect obviously tumour W256 in body, target cell NKM out of body and the degree of SOD,MDA in blood.