Nitrile oxides of the thiophene series: influence of steric factors on stability and reactivity in reactions of 1,3-dipolar cycloaddition
The synthesis of a series of di- and trialkyl-substituted thiophenecarbonitrile oxides is described. Their addition to styrene is studied together with the quantitative evaluation of the influence of different alkyl groups on the rate of the 1,3-dipolar cycloaddition reaction by the method of competing reactions.