Regio- and Stereoselective Tritiation of the Juvenoid Analog W 328
The juvenoid analog 2-(4-(2-(ethoxycarbamato)ethoxy)benzyl)-1-cyclohexanone ethylene acetal ( I ) (W 328) was labelled by 3 H in the benzyl position by the CESG method. 3 H NMR revealed the stereoselectivity of the labelling. The results are compared with the data published in the literature and discussed in the terms of stereoelectronic requirements.