Implementation of macrocycle conjugated antibodies for tumour-targetting
Monoclonal antibodies may be selectively functionalised with macrocyclic ligands, permitting the transport of an imaging or c totoxic metal radionuclide specifically to a tumour. Antibodies conju ated to p13) and (14)-membered tetraazamacrocycles allow 64Cu or 67Cu labefled antibody to be used for imaging or therapy.