Synthesis and stereochemistry of (−)-(10s)-6,10-dimethyl-6-aza-δ1,9-octahydroquinoline
Enantiomericalfy pure (−)-(10S)-6,10-dimethyl-6-am-Δ1,9-octahydroquinoline, which has been obtained from optically pure (3S)-1,3-dimethyl-3-(2-cyanoethyl)piperid-4-one, is a chiral intermediate for the preparation of novel biologically active compounds and an analog of piperidine and decahydroquinoline alkaloids. The chiroptical properties of the synthesized 6-azaoctahydroquinoline are examined.