Nucleophilic acylation of benzimidazole
Conditions that make it possible to realize the direct C(2) acylation of benzimidazole and some of its derivatives were found. It is shown that bis products, which are converted to 2-acylbenzimidazoles upon heating to 140–200 °C with acyl halides in the presence of triethylamine, are formed in attempts to carry out C(2) acylation.