Simultaneous Determination of 18 Photoinitiators Residues in Paper-made Packaging by Gas Chromatograph-Mass Spectrometry after Dispersive Solid Phase Extraction Cleanup
A method was developed for the simultaneous determination of 18 photoinitiators(PIs) residues in paper-made packaging by gas chromatograph-mass spectrometry(GC-MS) after dispersive solid phase extraction(d-SPE) cleanup.PIs were ultrasonically extracted by acetonitrile from water presoaked sample,followed by liquid-liquid distribution extraction with n-hexane-acetic ether(3 ∶ 7,V/V) and cleaned up by the mixed sorbents of anhydrous MgSO4 plus primary secondary amine(PSA) and octadecylsilane(C18) sorbent power.The ultimate solution was detected and quantified by GC-MS under selected ion monitoring mode by using anthracene D10 as the internal standard.All of the 18 PIs had good linear relationship(R2 0.997) in the concentrations of 0.01 to 0.2 mg/L.The recoveries of 18 PIs were in the range from 81.6% to 123.8% at three spike levels of 0.1,0.4 and 2 mg/m2 with relative standard deviation(RSD) less than 9.6%.The detection limits of target compounds in the method were ranged from 0.007 mg/m2 to 0.023 mg/m2.The real sample analysis showed that this simple and accurate method could be used for the determination of the residues of 18 PIs simultaneously in the paper-made packaging sample.