Preparation of glucose-sensitive chitosan-polyacrylic acid microcapsule and its characterization
Chitosan-polyacrylic acid(PAAC) microcapsules were prepared by reverse emulsion polymerization method with atoleine as oil phase and chitosan as water phase.GOD was immobilized onto the PAAC-grafted chitosan microcapsules by a carbodiimide method.The chitosan-PAAC microcapsules were characterized by infrared radiation spectroscopy,scanning electron microscope,ultraviolet spectrophotometer.Rhodamine B was chosen as a model molecule to vertify the controlled-release of microcapsule.The results show that the prepared microcapsule is circular and has a rough surface,inaddition,the release rate of Rhodamine B increases dramatically in the presence of 0.2 mol/L glucose.