Chromogenic Chemosensors for N‐Acetylaspartate Based on Chiral Ferrocene‐Bearing Thiourea Derivatives
A series of chiral ferrocene-containing thiourea derivatives have been synthesized, and their enantioselective recognition properties were investigated by UV/Vis titration. Receptors 5a and 6a exhibit excellent chiral recognition abilities towards N-acetylaspartate. The differences in solution colour can be observed directly by the naked eye. The minimum energy structures of 5a and 6a were also obtained by theoretical DFT calculations. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)