Structural insights into the similar modes of Nrf2 transcription factor recognition by the cytoplasmic repressor Keap1
The structure of mouse Keap1-DC complexed with the DLG motif peptide of Nrf2 transcription factor was determined at 1.9 Å resolution. The structure showed that the peptide binds to Keap1-DC at the bottom region of the β-propeller domain.