Cerebrospinal fluid studies in acute lymphoblastic leukemia and lymphosarcomas in children
: The author presents data of cerebrospinal fluid (CSF) examinations in children with acute lymphoblastic leukemia and lymphosarcomas. CSF syndromes are described which permit a conclusion on increased permeability of the hematoencephalic barrier in this patient population. CSF changes polymorphism, cyclic pattern are demonstrated, as is a functional specificity of the hematoencephalic barrier in acute lymphoblastic leukemia and lymphosarcomas consisting in a trend to CSF normalization. The author claims that CSF remissions may occur which do not coincide with findings of clinical and morphologic examinations of the CNS in children with hemoblastoses.