INVESTIGATION OF THE CHLORINATION OF 4-(PERFLUOROALKYL)-5-( p -TOLUENESULFONYL)URACILS. SYNTHESIS OF 5-CHLORO-6-(PERFLUOROALKYL)-5-( p -TOLUENESULFONYL)PYRIMIDINE-2,4(3 H ,5 H )-DIONES
Chlorination of 4-(perfluoroalkyl)-5-( p -toluenesulfonyl)-2,6-bis(trimethylsilyloxy)pyrimidines led to the formation of 5-chloro-6-(perfluoroalkyl)-5-( p -toluenesulfonyl)pyrimidine-2,4(3 H ,5 H )-diones, the structure of which was confirmed by NMR spectroscopy and X-ray structural analysis. The reactions of chlorinated pyrimidine-2,4(3 H ,5 H )-diones with nucleophiles were investigated. Authors: A. P. Gudz, A. S. Kanishchev, Yu. G. Vlasenko, A. N. Chernega, and Yu. G. Shermolovich English Translation in Chemistry of Heterocyclic Compounds , 2013, 49 (4), pp 591-597 http://link.springer.com/article/10.1007/s10593-013-1286-1