Role of Synbiotics in Improvement of Feed Tolerance and Weight Gain in the Newborns
Objective: To study the effect of Synbiotics on weight gain and feed tolerance of newborns. Methods: This prospective interventional trial included 50 newborns treated with a dietary supplement containing Synbiotics in addition to the routine treatment and 48 newborns served as control without Synbiotics supplement. The primary outcome was weight gain and feed tolerance. Results: Newborns in the Synbiotics group reached the full feeds earlier as compared to those in Control group (7.5 ± 4.26 days Vs 14.02 ± 7.88 days p=0.532) along with better weight gain(14.61 ± 9.6 grams per day Vs 2.97 ± 3.81 grams per day p=0.0000001). Conclusions: Newborns receiving Synbiotics are more likely to reach full feeds earlier and show better weight gain.