Complete remission of macroprolactinoma after long-term medical therapy with dopamine agonists.
Dopamine agonists are considered the preferred first-line treatment in patients with prolactinomas. However, surgery, alone or in combination with radiotheraphy, can achieve a definitive cure for this type of tumor.1 Complete remission of macroprolactinoma with dopamine agonists is uncommon with rates of recurrent hyperprolactinemia of 36–53% after 18 and 60 months, respectively.2–5 We report a patient with a macroprolactinoma who developed cure after long-term (10 years) medical treatment with dopamine agonists. A 26-year-old man was referred in 1995 for evaluation of a pituitary mass discovered on computed tomography scan …