Clinical Application of Tramadol and Propoxate in Tracheal Extubation
Objective To observe the effects of intravenous tramadol and propoxate on reducing stress response to emergence from tracheal extubation.Methods 60 cases of ASA I-II patients, which were scheduled for selective surgery of abdomen were randomly divided into three groups and received a standard general anesthesia consisting of fentanyl,propofol,rocuronium and isoflurane. After the operate, tramadol and propoxate (Group A),propoxate (Group B),the normal saline (Group C) were given respectively by I.V. injection. Postoperative tracheal extubation was performed when acceptable criteria was achieved. Non-invasive mean arterial pressure (MAP) ,heart rate (HR) and RPP were recorded at 2 min interval from the end of operation, Results Within the several minutes after extubation, In the Group A, the SBP,DBP,MAP,HR,RPP were no variation significantly (p0.05), the Group B and C was more increased than before extubation in this parameter, and compared with Group A, it had a difference obviously (P0.05).Conclusion Intravenous tramadol and propoxate can effectively relieve stress response to emergence from tracheal extubation.