Evidence of excretion of chlorinated hydrocarbon pesticides by the human liver
Conclusions1.The liver excretes DDT and dieldrin into the bile.2.The dieldrin content of bile from a worker having very high tissue stores is much greater than it is in persons with no occupational exposure. This suggests the existence of substrate-responsive excretory mechanisms.3.We have tentatively identified the aldehyde degradation product of dieldrin in adipose fat, bile,and gall stone. The ketone product has not been found in fat, bile, or gall stone.