Hydration Is an Important Factor to Regulate Thermodynamic Stability of a DNA Duplex under Molecular Crowding Conditions
By using a DNA duplex, (5'-GTTACTATATGA-3'/5'-TCATATAGTAAC-3') under molecular crowding conditions, it was revealed that hydration plays a significant role in the stability of the duplex, in contrast to viscosity and dielectric constant which have little effect.