Response to: “Questioning the evidence for BCI-based communication in the complete locked-in state”
Patients in completely locked-in state (CLIS) have no means of communication and present a highly challenging and daunting problem for the neuroscientist [1–3]. Until today, few groups have attempted to solve this problem, and only some have reported success in advancing the goal of providing a means of communication to patients in CLIS [4–7]. In his commentary, Dr. Spüler raises doubts about all the research efforts towards this goal but primarily about the results published in 2017 by Chaudhary and colleagues. Dr. Spüler bases the commentary on 2 main calculations: