Structure and electrochemistry of proteins harboring iron-sulfur clusters of different nuclearities. Part I. [4Fe-4S]+[2Fe-2S] iron-sulfur proteins.
In a recent series of review papers we have updated structure/electrochemistry of metalloproteins harboring single types of iron-sulfur clusters, namely {Fe(Cys)4}, {[Fe2S2](Cys)4}, {[Fe2S2](Cys)3(X)} (X=Asp, Arg, His), {[Fe2S2](Cys)2(His)2}, {[Fe3S4](Cys)3}, {[Fe4S4](Cys)4} and {[Fe4S4](SγCys)3(nonthiolate ligand)} cores, and their synthetic analogs. We now face with iron-sulfur proteins harboring iron-sulfur centres of different nuclearities. In this picture we start with proteins containing [4Fe-4S]+[2Fe-2S] clusters.