Structural Basis of Smoothened Activation in Hedgehog Signaling
(Cell 174, 312–324.e1–e16; July 12, 2018) In our paper, we reported crystal structures of sterol-activated Smoothened. It has come to our attention that we failed to cite an important contemporaneous contribution from Rohatgi and colleagues (Luchetti et al., 2016) who reported identification of cholesterol as the endogenous SMO agonist. This reference has been added online to the References and a citation added in the Introduction and the Discussion alongside the Huang et al., 2016 reference that we had already cited. We apologize to Drs Luchetti, Rohatgi, and colleagues and to the community for this breach of scholarship.