Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming
Geoffrey Schiebinger, Jian Shu,* Marcin Tabaka, Brian Cleary, Vidya Subramanian, Aryeh Solomon, Joshua Gould, Siyan Liu, Stacie Lin, Peter Berube, Lia Lee, Jenny Chen, Justin Brumbaugh, Philippe Rigollet, Konrad Hochedlinger, Rudolf Jaenisch, Aviv Regev,* and Eric S. Lander* *Correspondence: jianshu@broadinstitute.org (J.S.), aregev@broadinstitute.org (A.R.), lander@broadinstitute.org (E.S.L.) https://doi.org/10.1016/j.cell.2019.02.026