Social cognition in schizophrenia in comparison to bipolar disorder: A meta analysis
OBJECTIVE Cognitive dysfunction is a common characteristic of both schizophrenia and bipolar disorder (BP) While these deficits are more severe in schizophrenia, there is a significant overlap between conditions. However, it was hypothesized that social cognitive deficits might be more specific to schizophrenia. METHODS We conducted a meta analysis of studies comparing facial emotion recognition and theory of mind (ToM) abilities in schizophrenia and BP. 26 studies comparing 1301 patients with schizophrenia and 1075 with BP were included. RESULTS Schizophrenia patients significantly underperformed compared with BP patients in both facial emotion recognition (d=0.39) and ToM (d=0.57) Neurocognitive deficits significantly contributed to schizophrenia BP group differences for ToM. However, between group differences for social cognition were not statistically more severe than neurocognition. CONCLUSION Social cognitive impairment is more severe in schizophrenia in comparison to BP. However, between group differences are modest and are comparable to other neurocognitive differences between schizophrenia and BP. There is significant overlap in social cognitive performance deficits observed in both schizophrenia and BP.
Schizophrenia Research