Effects of early life stress on amygdala and striatal development
Highlights Evaluating stimuli in terms of threat/reward is critical to survival. The amygdala and striatum support affective valuation throughout life. Absence of stable caregiving early in life disrupts normative affective development. Such early life stress may alter the development of amygdala striatal interactions. Altered amygdala striatal function may mediate onset of internalizing illness.
Developmental Cognitive Neuroscience