Deposition, structure, physical and invitro characteristics of Ag doped b Ca3(PO4)2/chitosan hybrid composite coatings on Titanium metal.
Pure and five silver doped (0 5Ag) b tricalcium phosphate [b TCP, b Ca3(PO4)2]/chitosan composite coatings were deposited on Titanium (Ti) substrates and their properties that are relevant for applications in hard tissue replacements were assessed. Silver, b TCP and chitosan were combined to profit from their salient and complementary antibacterial and biocompatible features.The b Ca3(PO4)2 powders were synthesized by co precipitation. The characterization results confirmed the Ag( occupancy at the crystal lattice of b Ca3(PO4)2. The Ag dopedb Ca3(PO4)2/chitosan composite coatings deposited by electrophoresis showed good antibacterial activity and exhibited negative cytotoxic effects towards the human osteosarcoma cell line MG 63. The morphology of the coatings was observed by SEM and their efficiency against corrosion of metallic substrates was determined through potentiodynamic polarization tests.
Materials science engineering. C, Materials for biological applications