Prognostic significance of whole blood viscosity estimated by de Simone's formula in ST elevation myocardial infarction.
BACKGROUND We assessed the predictive value of estimated whole blood viscosity (WBV) in hospital and long term cardiovascular outcomes in patients with ST elevation myocardial infarction (STEMI) MATERIALS METHODS One thousand eight hundred and thirty five STEMI patients were followed up for median 34.6 months. WBV was calculated consistent with the de Simone's formula. RESULTS In hospital and long term major adverse cardiovascular events (MACE) demonstrated an incremental trend in ascending order of WBV tertiles at low and high shear rate. Kaplan Meier analysis showed a higher occurrence of long term MACE in third WBV tertiles compared with other tertiles. CONCLUSION WBV seems to be a feasible prognostic indicator of short and long term cardiovascular adverse events in patients with STEMI. As an easily available parameter, WBV may be utilized in identifying high risk patients for subsequent MACE.
Biomarkers in medicine