MECANISMUL DE PROTEOLIZA A FICOCIANINEI, PROTEINEI BIOACTIVE DIN SPIRULINA SUB ACTIUNEA PAPAINEI
Elaborarea unor procedee de o btinere a peptidelor bioactive din ficocianina prin intermediul hidrolizei proteolitice prezinta un interes sporit pentru cercetatori in contextul utilizarii acestora in calitate de remedii anticancer si pentru alte proprietati terapeutice. Peptidele derivate din ficocianina ar putea manifesta proprietati terapeutice mult mai pronuntate comparativ cu ficocianina. In prezenta lucrare sunt studiate dinamica proteolizei ficocianinei cu papaina si mecanismul de hidroliza a acestei proteine. Mechanism of proteolysis of C phycocyanin, bioactive protein from Spirulina, under the action of papain The elaboration of the procedures of obtaining of bioactive peptides derived from phycocyanin, as a result of it proteolytic hydrolysis presents great interest for researchers in the terms of theirs use as anti cancer drugs and for other therapeutic properties. It can be assumed that peptides derived from phycocyanin could manifest more pronounced therapeutic effects compared to phycocyanin. Dynamics of phycocyanin proteolisis by papain, as well as mechanism of phycocyanin hydrolysis were studied in the present work.