Residential exposure to traffic noise and risk of incident atrial fibrillation: A cohort study.
BACKGROUND Studies have found long term exposure to traffic noise to be associated with higher risk for hypertension, ischemic heart disease and stroke. We aimed to investigate the novel hypothesis that traffic noise increases the risk of atrial fibrillation (A fib) METHODS In a population based cohort of 57,053 people aged 50 64years at enrolment in 1993 1997, we identified 2692 cases of first ever hospital admission of A fib from enrolment to end of follow up in 2011 using a nationwide registry. The mean follow up time was 14.7years. Present and historical residential addresses were identified for all cohort members from 1987 to 2011. For all addresses, exposure to road traffic and railway noise was estimated using the Nordic prediction method and exposure to air pollution was estimated using a validated dispersion model. We used Cox proportional hazard model for the analyses with adjustment for lifestyle, socioeconomic position and air pollution. RESULTS A 10dB higher 5 year time weighted mean exposure to road traffic noise was associated with a 6% higher risk of A fib (incidence rate ratio (IRR) 1.06; 95% confidence interval (95% CI) 1.00 1.12) in models adjusted for factors related to lifestyle and socioeconomic position. The association followed a monotonic exposure response relationship. In analyses with adjustment for air pollution, NOx or NO2, there were no statistically significant associations between exposure to road traffic noise and risk of A fib; IRR: 1.04; (95% CI: 0.96 1.11) and IRR: 1.01; (95% CI: 0.94 1.09) respectively. Exposure to railway noise was not associated with A fib. CONCLUSION Exposure to residential road traffic noise may be associated with higher risk of A fib, though associations were difficult to separate from exposure to air pollution.
Environment international