EVALUATION OF IN VITRO ANTIOXIDANT POTENTIAL OF THE TOTAL CRUDE ALKALOID EXTRACT OF GLYCOSMIS PENTAPHYLLA (RETZ. CORREA LEAVES Original Article
Objective: The present investigation was undertaken to appraise the antioxidant properties and the total crude alkaloid extract of Glycosmis pentaphylla leaves. Methods: Radical attenuating abilities of total crude alkaloid extract were ascertained by six in vitro assays such as 2, 2 diphenyl 1 picryl hydrazyl (DPPH* radical scavenging assay, ferric reducing antioxidant power assay (FRAP) 2,2' azinobis (3 ethylbenzothiazoline 6 sulfonic acid (ABTS* radical scavenging assay, nitric oxide (NO) scavenging assay, hydroxyl radical (OH* Results: The total crude alkaloid extract showed a considerable antioxidant potentiality in comparison with the standards as evidenced by the IC scavenging assay, and reducing power capacity assessment. 50 values obtained in the DPPH* (966.93 ug/ml) FRAP (510.81 ug/ml) ABTS*(400.47 ug/ml) OH* Conclusion: These results suggest the potential of Glycosmis pentaphylla as a curative against free radical associated oxidative damage diseases. (1805.28 ug/ml) NO (1426.50 ug/ml) In the reducing power assay, the total crude alkaloid extract showed a concentration dependent reducing power potential.