Studies on the Effect of Molecular Weight on Biodegradable Polymer Membrane
PLA and PLGA have been extensively used for controlled drug delivery and used to fabricate device for tissue engineering. The objective of the present study was to know the effect of different molecular weight of PLLA and PLLGA. PLLA and PLLGA membrane was prepared using a solvent casting method. In vitro degradation of the blank membrane was characterized by techniques including NMR, SEM, BET. And examined the degradation of PLA PGA copolymer at different temperature range. The lower molecular weight, the more porosity and the smaller pore size. The degradation ratio of membrane increased with increasing test temperature.