Formulation and Evaluation of Gel Contains the Combination of Ethanol Extract Basil leaves (Ocimum sanctum L. and Soursop Leaves (Annona muricata L. as a Mosquito Repellent
The purpose of the present combination is to develop a mosquito repellant with a combination of active ingredient combination of ethanol extract of basil leaves (Ocimum sanctum L) and the soursop leaves (Annona muricata L) Mosquito repellant gel made as many as three formulas containing combinations of ethanol extract of basil leaves and soursop leaves (10% 2% Carbopol 940 with varying concentrations of 0.5% 0.75% and 1.0% as a gelling agent. Gel are evaluated physically and chemically via organoleptic examination, homogeneity, viscosity, flow properties, the scatter and pH. The formula of qualified physical and chemical stability testing conducted at room temperature, 4degC and 40degC. The results showed that the preparation is stable at room temperature and 4degC. Basil leaves extract provides optimum power protection at a concentration of 6% amounting to 93.17% and soursop leaves extract at a concentration of 8% amounting to 87.12% The combination gel formulation mosquito repellant ethanol extract of basil leaves and the soursop leaves (10% 2% have the capability of protection from 59.60 to 92.62% with 120 minutes long protection. Based on observations and test the stability of power protection, it can be concluded that the best formula is with a concentration of carbopol 940 is 1.0% as a gelling agent. Desi Nadya Aulena* Anny Victor Purba, Ratna Djamil Faculty of Pharmacy Pancasila University, SrengsengSawah, Jagakarsa,Jakarta 12640, Indonesia. Submission: 25 August 2016 Accepted: 1 September 2016 Published: 25 September 2016 www.ijppr.humanjournals.com Citation: Desi Nadya Aulena et al. Ijppr.Human, 2016; Vol. 7 (2) 10 18. 1