Recent application of oxa Michael reaction in complex natural product synthesis
Abstract The strategy of employing oxa Michael reaction in today's organic synthesis appears to be a big success due to its high efficiency in the construction of C O bonds. In this digest, recent advances of its application in the total synthesis of representative oxygen containing natural products, involving macrolides, terpenoids, chromanones and chromanes, polyoxygenated molecules and alkaloids et al. are discussed, with the aim of providing a complement to existing reviews.