An aggregation induced emission (AIE) ratiometric fluorescent cysteine probe with an exceptionally large blue shift
In this work, we developed a novel colorimetric and ratiometric fluorescence probe for the selective and sensitive monitoring of cysteine based on a coumarin Schiff base platform. This probe exhibited remarkable AIE characteristics with an exceptionally large blue shift (125 nm) which showed low emission in DMSO but strong aggregation induced emission in water solution. An excellent linear relationship of fluorescence intensity ratio (F450/F575) (R2 0.9922) versus Cys concentration in the range of 1 13 mM was obtained.