Indice: 1. Dalle Banche Dati Bibliografiche Pag. 2 2. Documenti Sleep in Children with Attention deficit/hyperactivity Disorder (adhd) before and after 6 month Treatment with Methylphenidate: a Pilot Study. Bibliografia Adhd Febbraio 2016 per La Ricerca Degli Articoli Pubblicati Nella Letteratura Sc
Children with ADHD may present with sleep disturbances that add to the impairment of the disorder. The longterm sleep effects of the first line pharmacological treatment for ADHD, i.e. psychostimulants, are unclear. In this pilot study, we compared polysomnographic variables in children with ADHD (n=11, aged 6 15 years) before pharmacological treatment, and in children without ADHD (n=22, aged 5 14 years) we also assessed polysomnographic changes in children with ADHD (n=7) after a 6 month treatment with methylphenidate immediate release (once or twice daily) Compared to children without ADHD, those with ADHD at baseline presented with significantly increased duration of awakenings (p 0.02) reduction in sleep efficiency (p=0.03) and increase in stage I (N1) (p<0.01) and reduction in stage II (N2) (p=0.02) and stage III IV (N3) percentages. Methylphenidate treatment did not significantly change any parameter of sleep architecture. Conclusion: Preliminary evidence from this pilot study shows that, compared to children without ADHD, those with ADHD presented a more fragmented and less effective sleep at baseline and that the 6 month methylphenidate treatment did not further negatively impact on sleep architecture. What is known: Children with ADHD may present with subjectively reported and/or objectively confirmed disturbances of sleep. The long term effects on sleep of the first line pharmacological treatment for ADHD, i.e. psychostimulants, are not clear. What is new: Our study showed that the 6 month continuous treatment with methylphenidate did not further negatively impact on sleep architecture in children with ADHD.