18590624
Fourier method for large-scale surface modeling and registration
Spherical harmonic (SPHARM) description is a powerful Fourier shape modeling method for processing arbitrarily shaped but simply connected 3D objects. As a highly promising method, SPHARM has been widely used in several domains including medical imaging. However, its primary use has been focused on modeling small or moderately-sized surfaces that are relatively smooth, due to challenges related to its applicability, robustness and scalability. This paper presents an enhanced SPHARM framework that addresses these issues and show that the use of SPHARM can expand into broader areas. In particular, we present a simple and efficient Fourier expansion method on the sphere that enables large scale modeling, and propose a new SPHARM registration method that aims to preserve the important homological properties between 3D models. Although SPHARM is a global descriptor, our experimental results show that the proposed SPHARM framework can accurately describe complicated graphics models and highly convoluted 3D surfaces and the proposed registration method allows for effective alignment and registration of these 3D models for further processing or analysis. These methods greatly enable the potential of applying SPHARM to broader areas such as computer graphics, medical imaging, CAD/CAM, bioinformatics, and other related geometric modeling and processing fields.
33719729
New Algorithms for Efficient Mining of Association Rules
Abstract Discovery of association rules is an important data mining task. Several algorithms have been proposed to solve this problem. Most of them require repeated passes over the database, which incurs huge I/O overhead and high synchronization expense in parallel cases. There are a few algorithms trying to reduce these costs. But they contain weaknesses such as often requiring high pre-processing cost to get a vertical database layout, containing much redundant computation in parallel cases, and so on. We propose new association mining algorithms to overcome the above drawbacks, through minimizing the I/O cost and effectively controlling the computation cost. Experiments on well-known synthetic data show that our algorithms consistently outperform a priori, one of the best algorithms for association mining, by factors ranging from 2 to 4 in most cases. Also, our algorithms are very easy to be parallelized, and we present a parallelization for them based on a shared-nothing architecture. We observe that our parallelization develops the parallelism more sufficiently than two of the best existing parallel algorithms.
6802677
A surface-based approach for classification of 3D neuroanatomic structures
We present a new framework for 3D surface object classification that combines a powerful shape description method with suitable pattern classification techniques. Spherical harmonic parameterization and normalization techniques are used to describe a surface shape and derive a dual high dimensional landmark representation. A point distribution model is applied to reduce the dimensionality. Fisher's linear discriminants and support vector machines are used for classification. Several feature selection schemes are proposed for learning better classifiers. After showing the effectiveness of this framework using simulated shape data, we apply it to real hippocampal data in schizophrenia and perform extensive experimental studies by examining different combinations of techniques. We achieve best leave-one-out cross-validation accuracies of 93% (whole set, N = 56) and 90% (right-handed males, N = 39), respectively, which are competitive with the best results in previous studies using different techniques on similar types of data. Furthermore, to help medical diagnosis in practice, we employ a threshold-free receiver operating characteristic (ROC) approach as an alternative evaluation of classification results as well as propose a new method for visualizing discriminative patterns.
2480556
Data Brokers: Building Collections through Automated Negotiation
Collecting digital materials is time-consuming and can gain from automation. Since each source – and even each acquisition – may involve a separate negotiation of terms, a collector may prefer to use a broker to represent his interests with owners. This paper describes the Data Broker Framework (DBF), which is designed to automate the process of digital object acquisition. For each acquisition, a negotiation agent is assigned to negotiate on the collector’s behalf, choosing from strategies in a strategy pool to automatically handle most bargaining cases and decide what to accept and what counteroffers to propose. We introduce NOODLE (Negotiation OntOlogy Description LanguagE) to formally specify terms in the negotiation domain.
6859814
Three-dimensional Models for Cardiac Bioelectricity Simulation: Cell to Organ
Computer models of the heart have become useful tools in improving understanding of cardiac electrical activation at the cellular level, and in analyzing mechanisms of arrhythmias and antiarrhythmic therapies. In this paper, we propose to use spherical harmonic (SPHARM) surface reconstruction and alignment methods to generate curvilinear meshes for finite element models of ventricular anatomy which incorporate detailed structural information. The endocardial and epicardial surfaces are defined by SPHARM, and the volume between these surfaces is divided into nested shells. Consequently, the resulting mesh comprises hexahedral elements. Using this novel SPHARM-based meshing method, the transmembrane potential propagation is simulated, based on FitzHugh—Nagumo reaction—diffusion equations. The dynamic electrical activation propagations are simulated on realistic cardiac data during a heart cycle. The obtained results clearly demonstrate an accurate resolution of the cardiac potential during the excitation. Our novel curvilinear mesh models have a great potential to be used in an improved simulation of cardiovascular pathologies for testing therapy strategies and planning interventions.
15225252
Morphometric Analysis of Hippocampal Shape in Mild Cognitive Impairment: An Imaging Genetics Study
A computational framework is presented for surface based morphometry to localize shape changes between groups of 3D objects. It employs the spherical harmonic (SPHARM) method for surface modeling and random field theory (RFT) for statistical inference. Several new components are introduced to overcome previous limitations: (1) a general linear model is used to facilitate controlling for covariates; (2) a new SPHARM registration method SHREC is proposed to better align SPHARM models; and (3) an estimated smoothness is used in RFT-based analysis to obtain more accurate results. This framework is applied in a mild cognitive impairment (MCI) study to examine hippocampal shape changes related to diagnostic and genetic conditions. Several interesting findings from our analyses suggest combining imaging phenotypes and genetic profiles has the potential to elucidate biological pathways for better understanding MCI and Alzheimer's disease.
29851215
Unified probabilistic models for face recognition from a single example image per person
This paper presents a new technique of unified probabilistic models for face recognition from only one single example image per person. The unified models, trained on an obtained training set with multiple samples per person, are used to recognize facial images from another disjoint database with a single sample per person. Variations between facial images are modeled as two unified probabilistic models: within-class variations and between-class variations. Gaussian Mixture Models are used to approximate the distributions of the two variations and exploit a classifier combination method to improve the performance. Extensive experimental results on the ORL face database and the authors' database (the ICT-JDL database) including totally 1,750 facial images of 350 individuals demonstrate that the proposed technique, compared with traditional eigenface method and some well-known traditional algorithms, is a significantly more effective and robust approach, for face recognition.
13746374
A Generalized Output-Coding Scheme with SVM for Multiclass Microarray Classification
Multiclass cancer classification based on microarray data is described. A generalized output-coding scheme combined with binary classifiers is used. Different coding strategies, decoding functions and feature selection methods are combined and validated on two cancer datasets: GCM and ALL. The effects of these different methods and their combinations are then discussed. The highest testing accuracies achieved are 78% and 100% for the two datasets respectively. The results are considered to be very good when compared with the other researchers’ work.
8221408
RTL concurrent fault simulation
The integrated circuit (IC) design has been pushed to hardware description language (HDL) description and high-level synthesis (HLS) techniques. The IC testing is also going to the high-level one. For the high-level testing, like gate level one, it needs a circuit model at high level such that, The model is easy to be converted and extended from the HDL descriptions. The model should be unified for multiple usages such as fault simulation, test generation, testability measure, etc. For various algorithms, it is easy to perform forward and backward tracing on the model, and easy to define fault models. In this paper, we try to construct such model and apply it to the fault simulation first.
14935665
Optimal Matrix Computing Using Vector Division with Sub-word Parallel
Available computing is expected to be effective and efficient in ubiquitous multimedia services. And, matrix multiplication is particular to ubiquitous computing such as image transformation so that it is urgent to exploit potential parallelism as well as data reuse in matrix multiplication. Therefore, based on synchronized data triggered architecture (SDTA), we propose a method of parallel vector division (PVD) as well as sub-word parallel (SWP) supported on SDTA to optimize the matrix computation on specified architecture. Experimental results show that PVD with SWP is suitable for matrix multiplication on SDTA instruction set architecture. Besides, we could extend the proposed model into other data-intensive computing on SDTA.
15979714
A New Architecture For Multiple-Precision Floating-Point Multiply-Add Fused Unit Design
The floating-point multiply-add fused (MAF) unit sets a new trend in the processor design to speed up floatingpoint performance in scientific and multimedia applications. This paper proposes a new architecture for the MAF unit that supports multiple IEEE precisions multiply-add operation (AtimesB+C) with Single Instruction Multiple Data (SIMD) feature. The proposed MAF unit can perform either one double-precision or two parallel single-precision operations using about 18% more hardware than a conventional double-precision MAF unit and with 9% increase in delay. To accommodate the simultaneous computation of two single-precision MAF operations, several basic modules of double-precision MAF unit are redesigned. They are either segmented by precision mode dependent multiplexers or attached by the duplicated hardware. The proposed MAF unit can be fully pipelined and the experimental results show that it is suitable for processors with floatingpoint unit (FPU).