( ( ( Isolated system ) ( ( A system ) ( ( in which ) ( ( neither ( ( matter nor ) energy ) ) ( is ( exchanged ( with ( the surroundings ) ) ) ) ) ) ) ) . )
(ROOT (NP (NP (ADJP (JJ Isolated)) (NN system)) (NP (NP (DT A) (NN system)) (SBAR (WHPP (IN in) (WHNP (WDT which))) (S (NP (CC neither) (NP (NN matter)) (CC nor) (NP (NN energy))) (VP (VBZ is) (VP (VBN exchanged) (PP (IN with) (NP (DT the) (NNS surroundings)))))))) (. .)))
Isolated system A system in which neither  matter nor energy is exchanged with the surroundings.
(ROOT (S (NP (DT A) (JJ sealed) (, ,) (JJ vacuum-insulated) (NN reaction) (NN flask)) (VP (VBZ approximates) (NP (NP (DT the) (NN condition)) (PP (IN of) (NP (NP (DT a) (VBN isolated) (NN system)) (, ,) (SBAR (WHPP (IN in) (WHNP (WDT which))) (S (NP (CC neither) (NP (NN matter)) (CC nor) (NP (NN heat))) (VP (MD can) (VP (VB be) (VP (VBN exchanged) (PP (IN between) (NP (NN system) (CC and) (NNS surroundings)))))))))))) (. .)))
A sealed, vacuum-insulated reaction flask approximates the condition of a isolated system, in which neither matter nor heat can be exchanged between system and surroundings.