( ( ( Both alleles ) ( of ( a gene ) ) ) ( ( must ( be ( ( mutated ( in ( ( autosomal ( recessive disorders ) ) ( for ( an individual ) ) ) ) ) ( to ( have ( ( a predisposition ) ( to cancer ) ) ) ) ) ) ) . ) )
(ROOT (S (NP (NP (DT Both) (NNS alleles)) (PP (IN of) (NP (DT a) (NN gene)))) (VP (MD must) (VP (VB be) (VP (VBN mutated) (PP (IN in) (NP (NP (JJ autosomal) (NN recessive) (NNS disorders)) (PP (IN for) (NP (DT an) (NN individual))))) (S (VP (TO to) (VP (VB have) (NP (NP (DT a) (NN predisposition)) (PP (TO to) (NP (NN cancer)))))))))) (. .)))
Both alleles of a gene must be mutated in autosomal recessive disorders for an individual to have a predisposition to cancer.
(ROOT (S (NP (NP (DT A) (NN person)) (VP (VBN affected) (PP (IN by) (NP (DT an) (JJ autosomal) (JJ dominant) (NN disorder))))) (VP (VBZ has) (NP (NP (CD one)) (VP (VBN mutated) (S (ADJP (JJ allele)))))) (. .)))
A person affected by an autosomal dominant disorder has one mutated allele.