( ( As ( explained above ) ) ( , ( ( 2,3 ( diphosphoglycerate molecules ) ) ( ( ( ( ( bind ( to ( the ( hemoglobin molecule ) ) ) ) ( in ( the ( taut configuration ) ) ) ) and ) ( ( ( stabilize ( ( that ( quaternary confirmation ) ) ( of ( the molecule ) ) ) ) , ) ( thereby ( favoring ( the ( low ( oxygen ( affinity state ) ) ) ) ) ) ) ) . ) ) ) )
(ROOT (S (SBAR (IN As) (S (VP (VBD explained) (ADVP (RB above))))) (, ,) (NP (CD 2,3) (JJ diphosphoglycerate) (NNS molecules)) (VP (VP (VBD bind) (PP (TO to) (NP (DT the) (NN hemoglobin) (NN molecule))) (PP (IN in) (NP (DT the) (JJ taut) (NN configuration)))) (CC and) (VP (VB stabilize) (NP (NP (DT that) (JJ quaternary) (NN confirmation)) (PP (IN of) (NP (DT the) (NN molecule)))) (, ,) (S (ADVP (RB thereby)) (VP (VBG favoring) (NP (DT the) (JJ low) (NN oxygen) (NN affinity) (NN state)))))) (. .)))
As explained above, 2,3 diphosphoglycerate molecules bind to the hemoglobin molecule in the taut configuration and stabilize that quaternary confirmation of the molecule, thereby favoring the low oxygen affinity state.
(ROOT (S (NP (NNP Hemoglobin)) (VP (VBZ is) (NP (NP (DT a) (NN carrier) (NN molecule)) (SBAR (WHNP (WDT that)) (S (VP (VBZ becomes) (ADJP (RBR less) (JJ effective) (PP (IN at) (NP (NP (VBG binding) (NN oxygen)) (PP (IN as) (NP (NN temperature) (NNS increases))))))))))) (. .)))