( ( Other ( important considerations ) ) ( ( ( ( are ( ( ( ( environmental factors ) ( like ( ( pH and ) temperature ) ) ) and ) ( ( shear sensitivity ) ( of ( the cells ) ) ) ) ) , ) ( especially ( in ( case ( of ( ( microcarrier cultures ) ( employing ( spinner ( ( bottles and ) fermentors ) ) ) ) ) ) ) ) ) . ) )
(ROOT (S (NP (JJ Other) (JJ important) (NNS considerations)) (VP (VBP are) (NP (NP (NP (JJ environmental) (NNS factors)) (PP (IN like) (NP (NN pH) (CC and) (NN temperature)))) (CC and) (NP (NP (NN shear) (NN sensitivity)) (PP (IN of) (NP (DT the) (NNS cells))))) (, ,) (PP (RB especially) (IN in) (NP (NP (NN case)) (PP (IN of) (NP (NP (NN microcarrier) (NNS cultures)) (VP (VBG employing) (NP (NN spinner) (NNS bottles) (CC and) (NNS fermentors)))))))) (. .)))
Other important considerations are environmental factors like pH and temperature and shear sensitivity of the cells, especially in case of microcarrier cultures employing spinner bottles and fermentors.
(ROOT (S (NP (NP (NNP Temperature)) (CC and) (NP (NN ph) (NN level))) (VP (VBP are) (ADJP (JJ important) (PP (IN in) (NP (NP (DT the) (NN activity)) (PP (IN of) (NP (DT an) (NN enzyme))))))) (. .)))