( ( ( Propofol and ) ( other ( consciousness-altering drugs ) ) ) ( ( ( ( ( are therefore ) ( antagonists ( of ( thalamus activity ) ) ) ) , ) ( possibly ( leading ( to ( a ( drug-induced ( comatose state ) ) ) ) ) ) ) . ) )
(ROOT (S (NP (NP (NNP Propofol)) (CC and) (NP (JJ other) (JJ consciousness-altering) (NNS drugs))) (VP (VBP are) (ADVP (RB therefore)) (NP (NP (NNS antagonists)) (PP (IN of) (NP (JJ thalamus) (NN activity)))) (, ,) (S (ADVP (RB possibly)) (VP (VBG leading) (PP (TO to) (NP (DT a) (JJ drug-induced) (NN comatose) (NN state)))))) (. .)))
Propofol and other consciousness-altering drugs are therefore antagonists of thalamus activity, possibly leading to a drug-induced comatose state.
(ROOT (S (NP (DT The) (NNS thalamus)) (VP (VBZ helps) (S (VP (TO to) (VP (VP (VB regulate) (NP (NN consciousness))) (, ,) (VP (VB arousal)) (, ,) (CC and) (VP (VB sleep) (NP (NNS states))))))) (. .)))