( ( ( Interference ( with ( the ( normal ( negative feedback ) ) ) ) ) ( that ( ( ( acid exerts ) ( on ( the ( gastrin-secreting cells ) ) ) ) ( can ( lead ( to ( ( ( ( ( hypergastrinaemia , ) ( increased ( acid secretion ) ) ) , ) and ) ( gastric metaplasia ) ) ) ) ) ) ) ) . )
(ROOT (S (VP (VB Interference) (PP (IN with) (NP (DT the) (JJ normal) (JJ negative) (NN feedback))) (SBAR (IN that) (S (NP (NP (JJ acid) (NNS exerts)) (PP (IN on) (NP (DT the) (JJ gastrin-secreting) (NNS cells)))) (VP (MD can) (VP (VB lead) (PP (TO to) (NP (NP (NN hypergastrinaemia)) (, ,) (NP (JJ increased) (JJ acid) (NN secretion)) (, ,) (CC and) (NP (JJ gastric) (NN metaplasia))))))))) (. .)))
Interference with the normal negative feedback that acid exerts on the gastrin-secreting cells can lead to hypergastrinaemia, increased acid secretion, and gastric metaplasia.
(ROOT (S (NP (NNP Gastrin)) (VP (VBZ signals) (NP (NP (DT the) (NN secretion)) (PP (IN of) (NP (JJ gastric) (NN acid))))) (. .)))