( ( ( The combination ) ( of ( ( hypoxia ( and ( toxic influences ) ) ) ( on ( the ( tubular ( epithelial cells ) ) ) ) ) ) ) ( ( results ( in ( ( ( ( ( ( ( ( impaired ( energy production ) ) and ) ( cellular respiration ) ) , ) ( damage ( to ( cell membranes ) ) ) ) , ) and ) ( interruption ( of ( the ( tubuloglomerular ( feedback mechanism ) ) ) ) ) ) ) ) . ) )
(ROOT (S (NP (NP (DT The) (NN combination)) (PP (IN of) (NP (NP (NN hypoxia) (CC and) (JJ toxic) (NNS influences)) (PP (IN on) (NP (DT the) (JJ tubular) (JJ epithelial) (NNS cells)))))) (VP (VBZ results) (PP (IN in) (NP (NP (NP (VBN impaired) (NN energy) (NN production)) (CC and) (NP (JJ cellular) (NN respiration))) (, ,) (NP (NP (NN damage)) (PP (TO to) (NP (NN cell) (NNS membranes)))) (, ,) (CC and) (NP (NP (NN interruption)) (PP (IN of) (NP (DT the) (NN tubuloglomerular) (NN feedback) (NN mechanism))))))) (. .)))
The combination of hypoxia and toxic influences on the tubular epithelial cells results in impaired energy production and cellular respiration, damage to cell membranes, and interruption of the tubuloglomerular feedback mechanism.
(ROOT (S (PP (IN As) (NP (NP (DT a) (NN result)) (PP (IN of) (NP (JJ cellular) (NN respiration))))) (, ,) (NP (NP (NN energy)) (PP (IN for) (NP (NN cell) (NNS processes)))) (VP (VBZ is) (VP (VBN released))) (. .)))