( It ( ( ( has recently ) ( been ( shown ( ( ( ( that ( collagen type ) ) ( II peptides ) ) ( as ( well as ) ) ) ( ( synthetic peptides ) ( containing ( ( ( the ( amino-terminal ( teleopeptide sequence ) ) ) ( of ( type ( II collagen ) ) ) ) ( ( ( ( ( inhibit ( collagen synthesis ) ) , ) ( ( deplete ( cartilage matrix ) ) PG ) ) and ) ( enhance ( gelatinases ( in ( ( cultured ( articular cartilage ) ) ( -LRB- ( 142 -RRB- ) ) ) ) ) ) ) ) ) ) ) ) ) ) . ) )
(ROOT (S (NP (PRP It)) (VP (VBZ has) (ADVP (RB recently)) (VP (VBN been) (VP (VBN shown) (NP (NP (NP (DT that) (NN collagen) (NN type)) (ADJP (NNP II) (JJ peptides))) (CONJP (RB as) (RB well) (IN as)) (NP (NP (JJ synthetic) (NNS peptides)) (VP (VBG containing) (S (NP (NP (DT the) (JJ amino-terminal) (NN teleopeptide) (NN sequence)) (PP (IN of) (NP (NN type) (NNP II) (NNP collagen)))) (VP (VP (VB inhibit) (NP (NN collagen) (NN synthesis))) (, ,) (VP (VB deplete) (NP (NN cartilage) (NN matrix)) (ADVP (RB PG))) (CC and) (VP (VB enhance) (NP (NP (NNS gelatinases)) (PP (IN in) (NP (NP (JJ cultured) (NN articular) (NN cartilage)) (PRN (-LRB- -LRB-) (NP (CD 142)) (-RRB- -RRB-)))))))))))))) (. .)))
It has recently been shown that collagen type II peptides as well as synthetic peptides containing the amino-terminal teleopeptide sequence of type II collagen inhibit collagen synthesis, deplete cartilage matrix PG and enhance gelatinases in cultured articular cartilage (142).
(ROOT (S (NP (JJ Lamprey) (NN cartilage)) (VP (VBZ contains) (NP (DT no) (NN collagen))) (. .)))