( They ( ( claimed ( that ( ( ( ( low levels ) ( of ( AKT activity ) ) ) ( associated ( with ( ( elevated levels ) ( of FOXOs ) ) ) ) ) ( are ( required ( to ( maintain ( ( the ( function ( and ( immature state ) ) ) ) ( of ( ( leukemia-initiating cells ) ( -LRB- ( LICs -RRB- ) ) ) ) ) ) ) ) ) ) ) ) . ) )
(ROOT (S (NP (PRP They)) (VP (VBD claimed) (SBAR (IN that) (S (NP (NP (JJ low) (NNS levels)) (PP (IN of) (NP (NNP AKT) (NN activity))) (VP (VBN associated) (PP (IN with) (NP (NP (JJ elevated) (NNS levels)) (PP (IN of) (NP (NNP FOXOs))))))) (VP (VBP are) (VP (VBN required) (S (VP (TO to) (VP (VB maintain) (NP (NP (DT the) (NN function) (CC and) (NN immature) (NN state)) (PP (IN of) (NP (NP (JJ leukemia-initiating) (NNS cells)) (PRN (-LRB- -LRB-) (NP (NNP LICs)) (-RRB- -RRB-))))))))))))) (. .)))
They claimed that low levels of AKT activity associated with elevated levels of FOXOs are required to maintain the function and immature state of leukemia-initiating cells (LICs).
(ROOT (S (NP (DT A) (PRN (-LRB- -LRB-) (NP (NN n)) (-RRB- -RRB-)) (NN cell)) (VP (VBZ is) (NP (NP (DT the) (JJS lowest) (NN level)) (PP (IN of) (NP (NN organism))) (SBAR (WHNP (WDT that)) (S (VP (MD can) (VP (VB perform) (NP (NP (DT all) (NNS activities)) (VP (VBN required) (PP (IN for) (NP (NN life))))))))))) (. .)))