( ( While ( ( these ( adaptor molecules ) ) ( possess ( no ( intrinsic ( enzymatic activity ) ) ) ) ) ) ( , ( ( their ( ability ( to ( mediate ( protein-protein interactions ) ) ) ) ) ( ( is ( vital ( for ( ( the ( ( integration and ) propagation ) ) ( of ( signal ( transduction cascades ) ) ) ) ) ) ) . ) ) ) )
(ROOT (S (SBAR (IN While) (S (NP (DT these) (NN adaptor) (NNS molecules)) (VP (VBP possess) (NP (DT no) (JJ intrinsic) (JJ enzymatic) (NN activity))))) (, ,) (NP (PRP$ their) (NN ability) (S (VP (TO to) (VP (VB mediate) (NP (JJ protein-protein) (NNS interactions)))))) (VP (VBZ is) (ADJP (JJ vital) (PP (IN for) (NP (NP (DT the) (NN integration) (CC and) (NN propagation)) (PP (IN of) (NP (NN signal) (NN transduction) (NNS cascades))))))) (. .)))
While these adaptor molecules possess no intrinsic enzymatic activity, their ability to mediate protein-protein interactions is vital for the integration and propagation of signal transduction cascades.
(ROOT (S (NP (JJ Enzymatic) (NNS cascades)) (VP (VBP help) (VP (VB amplify) (NP (NP (DT the) (NNS effects)) (PP (IN of) (NP (NN extracellular) (NNS signals)))))) (. .)))