( ( In ( contrast ( to ( ( ( ( secondary or ) acquired ) ( immune ( deficiency diseases ) ) ) ( caused ( by ( infectious ( , ( chemical ( or ( radiological agents ) ) ) ) ) ) ) ) ) ) ) ( , ( ( the ( primary ( immunodeficiency diseases ) ) ) ( ( are ( ( caused ( by ( intrinsic dysfunction ) ) ) ( in ( ( the cells ) ( of ( ( ( the ( immune system ) ) , ) ( often ( brought ( about ( by ( inherited ( genetic defects ) ) ) ) ) ) ) ) ) ) ) ) . ) ) ) )
(ROOT (S (PP (IN In) (NP (NP (NN contrast)) (PP (TO to) (NP (NP (ADJP (JJ secondary) (CC or) (JJ acquired)) (JJ immune) (NN deficiency) (NNS diseases)) (VP (VBN caused) (PP (IN by) (NP (JJ infectious) (, ,) (JJ chemical) (CC or) (JJ radiological) (NNS agents)))))))) (, ,) (NP (DT the) (JJ primary) (JJ immunodeficiency) (NNS diseases)) (VP (VBP are) (VP (VBN caused) (PP (IN by) (NP (JJ intrinsic) (NN dysfunction))) (PP (IN in) (NP (NP (DT the) (NNS cells)) (PP (IN of) (NP (NP (DT the) (JJ immune) (NN system)) (, ,) (VP (ADVP (RB often)) (VBN brought) (PP (IN about) (IN by) (NP (VBN inherited) (JJ genetic) (NNS defects)))))))))) (. .)))
In contrast to secondary or acquired immune deficiency diseases caused by infectious, chemical or radiological agents, the primary immunodeficiency diseases are caused by intrinsic dysfunction in the cells of the immune system, often brought about by inherited genetic defects.
(ROOT (S (NP (NP (NNP Exposure)) (PP (TO to) (NP (JJ chemical) (CC or) (JJ biological) (NNS agents)))) (VP (MD can) (VP (VB cause) (NP (DT an) (VBN acquired) (NN immunodeficiency)) (ADVP (RB later)) (PP (IN in) (NP (NN life))))) (. .)))