( ( ( ( ( ( ( The oxidation ) ( of guanine ) ) ( ( ( proceeds ( more rapidly ) ) ( as ( the ( free nucleotide ) ) ) ) ( than ( in DNA ) ) ) ) , ) and ) ( ( removal ( of ( 8-oxo-dGTP ( from ( the ( nucleotide pool ) ) ) ) ) ) ( is ( ( an ( important step ) ) ( in ( ( the prevention ) ( of ( 8-oxo-dG lesions ) ) ) ) ) ) ) ) . )
(ROOT (S (S (NP (NP (DT The) (NN oxidation)) (PP (IN of) (NP (NN guanine)))) (VP (VBZ proceeds) (ADVP (RBR more) (RB rapidly)) (PP (IN as) (NP (DT the) (JJ free) (NN nucleotide))) (ADVP (IN than) (PP (IN in) (NP (NNP DNA)))))) (, ,) (CC and) (S (NP (NP (NN removal)) (PP (IN of) (NP (NP (JJ 8-oxo-dGTP)) (PP (IN from) (NP (DT the) (JJ nucleotide) (NN pool)))))) (VP (VBZ is) (NP (NP (DT an) (JJ important) (NN step)) (PP (IN in) (NP (NP (DT the) (NN prevention)) (PP (IN of) (NP (JJ 8-oxo-dG) (NNS lesions)))))))) (. .)))
The oxidation of guanine proceeds more rapidly as the free nucleotide than in DNA, and removal of 8-oxo-dGTP from the nucleotide pool is an important step in the prevention of 8-oxo-dG lesions.
(ROOT (S (ADVP (RB Deletions)) (VP (VB remove) (NP (NP (QP (CD one) (CC or) (JJR more)) (NNS nucleotides)) (PP (IN from) (NP (DT the) (NN dna)))))))