( Therefore ( , ( ( many patients ) ( ( will ( ( require ( second-line therapy ) ) ( if ( ( response ( to ( ( salicylates and ) ( other ( non-steroidal ( anti-inflammatory drugs ) ) ) ) ) ) ( is inadequate ) ) ) ) ) . ) ) ) )
(ROOT (S (ADVP (RB Therefore)) (, ,) (NP (JJ many) (NNS patients)) (VP (MD will) (VP (VB require) (NP (JJ second-line) (NN therapy)) (SBAR (IN if) (S (NP (NP (NN response)) (PP (TO to) (NP (NP (NNS salicylates)) (CC and) (NP (JJ other) (JJ non-steroidal) (JJ anti-inflammatory) (NNS drugs))))) (VP (VBZ is) (ADJP (JJ inadequate))))))) (. .)))
Therefore, many patients will require second-line therapy if response to salicylates and other non-steroidal anti-inflammatory drugs is inadequate.
(ROOT (S (NP (JJ Inflammatory) (NN response)) (VP (VBZ is) (NP (NP (DT the) (JJ second) (NN line)) (PP (IN of) (NP (NN defense))))) (. .)))