( ( In addition ) ( , ( ( ( ( the ( heart 's ) ) ( extracellular matrix ) ) ( -LRB- ( ( ( the substrate ) ( of ( heart scaffold ) ) ) -RRB- ) ) ) ( ( ( signalled ( the ( human cells ) ) ) ( into ( becoming ( ( the ( specialised cells ) ) ( needed ( for ( proper ( heart function ) ) ) ) ) ) ) ) . ) ) ) )
(ROOT (S (PP (IN In) (NP (NN addition))) (, ,) (NP (NP (NP (DT the) (NN heart) (POS 's)) (NN extracellular) (NN matrix)) (PRN (-LRB- -LRB-) (NP (NP (DT the) (NN substrate)) (PP (IN of) (NP (NN heart) (NN scaffold)))) (-RRB- -RRB-))) (VP (VBD signalled) (NP (DT the) (JJ human) (NNS cells)) (PP (IN into) (S (VP (VBG becoming) (NP (NP (DT the) (JJ specialised) (NNS cells)) (VP (VBN needed) (PP (IN for) (NP (JJ proper) (NN heart) (NN function))))))))) (. .)))
In addition, the heart's extracellular matrix (the substrate of heart scaffold) signalled the human cells into becoming the specialised cells needed for proper heart function.
(ROOT (S (PP (IN In) (NP (NNS humans))) (, ,) (NP (DT the) (NN heart)) (VP (VBZ is) (NP (DT the) (JJ first) (NN organ) (S (VP (TO to) (VP (VP (VB form)) (CC and) (VP (VB become) (ADJP (JJ functional)))))))) (. .)))