( ( ( The ( ( ( major and ) ( extremely significant ) ) difference ) ) ( between ( ( prokaryotes and ) eukaryotes ) ) ) ( ( is ( that ( eukaryotes ( ( ( have ( ( ( a nucleus ) and ) ( membrane-bound organelles ) ) ) , ) ( while ( prokaryotes ( do not ) ) ) ) ) ) ) . ) )
(ROOT (S (NP (NP (DT The) (ADJP (ADJP (JJ major)) (CC and) (ADJP (RB extremely) (JJ significant))) (NN difference)) (PP (IN between) (NP (NNS prokaryotes) (CC and) (NNS eukaryotes)))) (VP (VBZ is) (SBAR (IN that) (S (NP (NNS eukaryotes)) (VP (VBP have) (NP (NP (DT a) (NN nucleus)) (CC and) (NP (JJ membrane-bound) (NNS organelles))) (, ,) (SBAR (IN while) (S (NP (NNS prokaryotes)) (VP (VBP do) (RB not)))))))) (. .)))
The major and extremely significant difference between prokaryotes and eukaryotes is that eukaryotes have a nucleus and membrane-bound organelles, while prokaryotes do not.
(ROOT (S (NP (NNS Eukaryotes)) (VP (VBP have) (NP (NP (NNS nuclei)) (CC and) (NP (ADJP (JJ other)) (ADJP (RB membrane) (VBN bound)) (NNS organelles)))) (. .)))