( ( ( A reaction ) ( that ( has ( ( ( ( a ( positive change ) ) ( in entropy ) ) and ) ( ( a ( negative change ) ) ( in enthalpy ) ) ) ) ) ) ( ( will ( be ( strongly ( favored ( to ( proceed ( in ( ( ( the ( forward direction ) ) , ) ( i.e ( ( the reaction ) ( will ( have ( ( a ( ( very large ) equilibrium ) ) constant ) ) ) ) ) ) ) ) ) ) ) ) ) . ) )
(ROOT (S (NP (NP (DT A) (NN reaction)) (SBAR (WHNP (WDT that)) (S (VP (VBZ has) (NP (NP (NP (DT a) (JJ positive) (NN change)) (PP (IN in) (NP (NN entropy)))) (CC and) (NP (NP (DT a) (JJ negative) (NN change)) (PP (IN in) (NP (NN enthalpy))))))))) (VP (MD will) (VP (VB be) (VP (ADVP (RB strongly)) (VBN favored) (S (VP (TO to) (VP (VB proceed) (PP (IN in) (NP (NP (DT the) (JJ forward) (NN direction)) (, ,) (NP (NP (NN i.e)) (SBAR (S (NP (DT the) (NN reaction)) (VP (MD will) (VP (VB have) (NP (NP (DT a) (ADJP (RB very) (JJ large)) (NN equilibrium)) (ADJP (JJ constant)))))))))))))))) (. .)))
A reaction that has a positive change in entropy and a negative change in enthalpy will be strongly favored to proceed in the forward direction, i.e the reaction will have a very large equilibrium constant.
(ROOT (S (NP (DT A) (JJ negative) (NN enthalpy) (NN change)) (VP (VBZ is) (VP (VBN observed) (PP (IN in) (NP (DT an) (JJ exothermic) (NN reaction))))) (. .)))