( ( ( ( ( Respiratory depression ) , ) ( ( defined ( as ( respiratory rate ) ) ) ( ( ( less ( than 10 ) ) breaths ) ( per minute ) ) ) ) , ) ( ( was ( monitored ( in ( ( 12 trials ) ( of ( ( ( 485 ( opioid patients ) ) and ) ( 250 controls ) ) ) ) ) ) ) . ) )
(ROOT (S (NP (NP (JJ Respiratory) (NN depression)) (, ,) (VP (VBN defined) (PP (IN as) (NP (JJ respiratory) (NN rate))) (NP (NP (QP (JJR less) (IN than) (CD 10)) (NNS breaths)) (PP (IN per) (NP (NN minute))))) (, ,)) (VP (VBD was) (VP (VBN monitored) (PP (IN in) (NP (NP (CD 12) (NNS trials)) (PP (IN of) (NP (NP (JJ 485) (JJ opioid) (NNS patients)) (CC and) (NP (CD 250) (NNS controls)))))))) (. .)))
Respiratory depression, defined as respiratory rate less than 10 breaths per minute, was monitored in 12 trials of 485 opioid patients and 250 controls.
(ROOT (S (NP (NP (DT The) (JJ normal) (NN respiratory) (NN rate)) (PP (IN per) (NP (NP (NN minute)) (PP (IN in) (NP (JJ adult) (NNS humans)))))) (VP (VBZ is) (NP (CD 12-18) (NNS breaths))) (. .)))