Sen. John McCain has been diagnosed with brain cancer, his office said. The tumor, known as glioblastoma, was found while the 80-year-old Arizona Republican was having an operation to remove a blood clot from his eye. Glioblastoma is a highly malignant and fast-growing type of tumor, according to the American Brain Tumor Association. President Donald Trump said McCain "has always been a fighter" as other lawmakers expressed their support.

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The Morning Brief is published Mondays through Fridays. Email Morning Brief writer Melissa Chan at melissa.chan@time.com .</s>Sen. John McCain, R-Ariz., arrives on Capitol Hill on July 11, 2017 in Washington. McCain has been diagnosed with a brain tumor after a blood clot was removed. File

Jacquelyn Martin / AP file</s>Late Wednesday evening it was announced Senator John McCain has been diagnosed with brain cancer after he underwent a procedure to remove a blood clot last week.</s>Longtime Republican Sen. John McCain has been diagnosed with brain cancer, his office confirmed Wednesday.

The Arizona senator and former Republican presidential nominee is currently recovering from a July 14 operation to remove a blood clot from above his left eye, which his doctors confirmed had been caused by a “primary brain tumor known as a glioblastoma,” his office said in a statement.

McCain, who is being treated at the Mayo Clinic in Phoenix, is reviewing further treatment options including chemotherapy and radiation.

“The Senator’s doctors say he is recovering from his surgery ‘amazingly well’ and his underlying health is excellent,” the statement said.

McCain has repeatedly been treated for skin cancer, having had four melanomas removed: one on his shoulder in 1993; one on his left arm and one on his left temple in 2000; and one on his nose in 2002. The surgeries became a point of contention for detractors questioning his fitness as a candidate in the 2008 presidential election, though several prominent physicians pointed out at the time that the greatest risk of melanoma recurrence is in the “first few years after detection.”

Doctors surveyed by the New York Times this week said his history of melanoma could have prompted the brain scan that led to his most recent diagnosis.

McCain’s daughter, the former political commentator Meghan McCain, also issued a statement saying she and her family are living “with the anxiety about what comes next.”</s>Yesterday news broke that Senator John McCain has brain cancer. Reports have said the tumor was surgically removed successfully. Many celebrities and figures have reacted on social media. We are wishing the best to the Senator and all his loved ones.</s>WASHINGTON, D.C. (WSPA) – Members of CNN have reported that Senator John McCain of Arizona has been diagnosed with brain cancer as of Wednesday.

Sen. McCain recently had surgery to address a tumor in his brain, according to the CNN report.

The Mayo Clinic reported to news outlets that Sen. McCain’s cancer has been specifically diagnosed as glioblastoma.

We will update when more information becomes available.</s>Former US presidential candidate Senator John McCain has been diagnosed with a brain tumour after having a blood clot removed.

Doctors said the Arizona senator has been diagnosed with glioblastoma, an aggressive cancer.

The 80-year-old senator and his family are reviewing further treatment, including a combination of chemotherapy and radiation.

The senator has been recovering at his Arizona home after doctors at the Mayo Clinic removed a blood clot above his left eye.

The doctors said Mr McCain is recovering from his surgery amazingly well and his underlying health is excellent.

Mr McCain was the Republican Party’s presidential nominee in 2008.

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He was a navy pilot, and was shot down over Vietnam and held as a prisoner for more than five years.

His office said: “On Friday, July 14, Sen. John McCain underwent a procedure to remove a blood clot from above his left eye at Mayo Clinic Hospital in Phoenix.

“Subsequent tissue pathology revealed that a primary brain tumour known as a glioblastoma was associated with the blood clot.”

Mr McCain’s absence from Washington had forced Majority Leader Mitch McConnell to delay action on health care legislation.

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Mr McConnell said: “John McCain is a hero to our conference and a hero to our country. He has never shied from a fight and I know that he will face this challenge with the same extraordinary courage that has characterised his life.

The entire Senate family’s prayers are with John, Cindy and his family, his staff, and the people of Arizona he represents so well.”

Mr McCain and his running mate Sarah Palin lost to Barack Obama in 2008.

Mr Obama tweeted: “John McCain is an American hero & one of the bravest fighters I’ve ever known. Cancer doesn’t know what it’s up against. Give it hell, John.”</s>Arizona Sen. John McCain, the 2008 Republican presidential nominee with a well-known maverick streak that often vexes his GOP colleagues, has been diagnosed with a brain tumor, his office said in a statement Wednesday.

The 80-year-old lawmaker has glioblastoma, an aggressive cancer, according to doctors at the Mayo Clinic in Phoenix, where McCain had a blood clot removed from above his left eye last Friday. The senator and his family are reviewing further treatment, including a combination of chemotherapy and radiation.

"Subsequent tissue pathology revealed that a primary brain tumor known as a glioblastoma was associated with the blood clot," his office said in a statement.

About 20,000 people in the U.S. each year are diagnosed with a glioblastoma, a particularly aggressive type of brain tumor. The American Cancer Society puts the five-year survival rate for patients over 55 at about 4 percent.

The tumor digs tentacle-like roots into normal brain tissue. Patients fare best when surgeons can cut out all the visible tumor, which happened with McCain's tumor, according to his office. That isn't a cure; cancerous cells that aren't visible still tend to lurk, the reason McCain's doctors are considering further treatment, including chemotherapy and radiation.

It's the same type of tumor that struck McCain's close Democratic colleague in legislative battles, the late Ted Kennedy of Massachusetts.

The senator and chairman of the Armed Services Committee had been recovering at his Arizona home. His absence had forced Majority Leader Mitch McConnell, R-Ky., to delay action on health care legislation. McCain had been slated to oversee debate of the sweeping defense policy bill in the coming weeks.

As word spread of his diagnosis, President Donald Trump, former rival Barack Obama and McCain's Senate colleagues, Republicans and Democrats, offered their prayers and support.

"Senator John McCain has always been a fighter. Melania and I send our thoughts and prayers to Senator McCain, Cindy, and their entire family. Get well soon," Trump said.

Obama, who dashed McCain's dreams of the presidency, said in a tweet: "John McCain is an American hero & one of the bravest fighters I've ever known. Cancer doesn't know what it's up against. Give it hell, John."

A Navy pilot, McCain was shot down over Vietnam and held as a prisoner of war for 5½ years.

McConnell called McCain a "hero to our conference and a hero to our country. He has never shied from a fight and I know that he will face this challenge with the same extraordinary courage that has characterized his life."

 Democratic Sen. Chris Coons of Delaware said McCain "is a fighter, and I am hopeful he will once again beat the odds."

Arizona Gov. Doug Ducey described McCain as "undoubtedly the toughest man in the United States Senate."

 Politics aside, McCain and Bill Clinton developed a strong friendship, and the former president said: "As he's shown his entire life, don't bet against John McCain. Best wishes to him for a swift recovery."

McCain's office disclosed the removal of the blood clot late Saturday and said the senator was awaiting pathology reports. In the past, McCain had been treated for melanoma, but a primary tumor is unrelated. Doctors said McCain is recovering from his surgery amazingly well and his underlying health is excellent.

In a statement on Twitter, his daughter, Meghan McCain, spoke of the shock of the news and the anxiety over what happens next. "My love for my father is boundless and like any daughter I cannot and do not wish to be in a world without him. I have faith that those days remain far away," she said.

With his irascible grin and fighter-pilot moxie, McCain was elected to the Senate from Arizona six times, but twice thwarted in seeking the presidency.

An upstart presidential bid in 2000 didn't last long. Eight years later, he fought back from the brink of defeat to win the GOP nomination, only to be overpowered by Obama. McCain chose a little-known Alaska governor as his running mate in that race, and helped turn Sarah Palin into a national political figure.

After losing to Obama in an electoral landslide, McCain returned to the Senate, determined not to be defined by a failed presidential campaign. And when Republicans took control of the Senate in 2015, McCain embraced his new job as chairman of the powerful Armed Services Committee, eager to play a big role "in defeating the forces of radical Islam that want to destroy America."

Throughout his long tenure in Congress, McCain has played his role with trademark verve, at one hearing dismissing a protester by calling out, "Get out of here, you low-life scum."

He tangled with McConnell over campaign finance, joined forces with Democrats on immigration and most recently had a very public spat with Sen. Rand Paul. McCain said the Kentucky Republican was working for Russian President Vladimir Putin after he blocked a vote on allowing Montenegro into NATO. Paul said McCain had gotten "unhinged."

In 2016, McCain stuck by Trump at times seemingly through gritted teeth — until the release a month before the election of a lewd audio in which Trump said he could kiss and grab women. Declaring that the breaking point, McCain withdrew his support and said he would write in "some good conservative Republican who's qualified to be president."

He had largely held his tongue earlier in the campaign when Trump questioned his status as a war hero by saying: "He was a war hero because he was captured. I like people who weren't captured."

 ___

 AP Medical Writer Lauran Neergaard and writer Nancy Benac contributed to this report.</s>John McCain, the Arizona senator and former Republican presidential candidate, has been diagnosed with brain cancer.

A brain tumor known as a glioblastoma was removed from McCain along with a blood clot in a surgery at the Mayo Clinic on Friday, a spokesperson said on Wednesday.

McCain's office had only previously announced that the blood clot had been removed from above the 80-year-old's left eye.

The Mayo Clinic said in a statement released by McCain's office: “The senator and his family are reviewing further treatment options with his Mayo Clinic care team. Treatment options may include a combination of chemotherapy and radiation. The senator's doctors say he is recovering from his surgery 'amazingly well' and his underlying health is excellent.”

The surgery had forced McCain to stay in Arizona this week and miss votes in the Senate. It had led to a delay in the vote on the Senate Republican bill to repeal and replace the Affordable Care Act (ACA), which was originally scheduled for Monday. Since the delay was announced, a sufficient number of Republican senators came forward to express their opposition to the bill and forced the majority leader, Mitch McConnell, to shelve it and instead try to push a vote on a clean repeal of the ACA.

In a statement, the Arizona senator's spokesperson said that “in the aftermath of his diagnosis, further consultations with [the] Mayo Clinic care team will indicate when he will return to the United States Senate”.

An extended absence would likely make it even more difficult for Republicans to repeal or replace the ACA, popularly known as Obamacare. Senate Republicans have a narrow 52-48 majority and, with the tie-breaking vote of Mike Pence, can only afford to lose two votes if McCain is present. His absence means that two Republican “no” votes would now sink any legislation if all 48 Democrats are unified in opposition.

McCain, who was re-elected to his sixth term in the Senate in 2016, was the Republican party's presidential nominee in 2008 and finished second to George W Bush in the 2000 GOP presidential primary. Prior to his career in politics, McCain served as an aviator in the US navy, and was held as prisoner of war for five and a half years during the Vietnam war. While being held captive by the north Vietnamese, McCain was repeatedly subjected to torture. He retired as a captain after earning a number of decorations including the Silver Star, the Bronze Star and the Distinguished Flying Cross.

The Arizona senator's illness sparked an outpouring of support from both sides of the aisle.

In a statement, Donald Trump said: “Senator John McCain has always been a fighter. Melania and I send our thoughts and prayers to Senator McCain, Cindy, and their entire family. Get well soon.” Trump, who famously set off a political firestorm in 2015 by saying McCain was “not a war hero”, said earlier in the week of the Arizona senator: “We hope John McCain gets better very soon because we miss him. He's a crusty voice in Washington. Plus we need his vote. And he'll be back.”

Barack Obama, against whom McCain ran in the 2008 presidential election, tweeted: “John McCain is an American hero & one of the bravest fighters I've ever known. Cancer doesn't know what it's up against. Give it hell, John.”

Barack Obama (@BarackObama)

John McCain is an American hero & one of the bravest fighters I’ve ever known. Cancer doesn’t know what it’s up against. Give it hell, John.

July 20, 2017 

A number of McCain's colleagues in the Senate also expressed their well wishes. In a statement, Mitch McConnell said: “John McCain is a hero to our Conference and a hero to our country. He has never shied from a fight and I know that he will face this challenge with the same extraordinary courage that has characterized his life. The entire Senate family's prayers are with John, Cindy and his family, his staff, and the people of Arizona he represents so well. We all look forward to seeing this American hero again soon.”

Outside a meeting of Senate Republicans to discuss healthcare reform on Wednesday night, senator John Hoeven of North Dakota said they had learned of the diagnosis during the meeting.

“It was very emotional – almost kind of stunned disbelief,” Hoeven told reporters. Senator James Lankford, of Oklahoma, then led them in prayer.

Hoeven said the senators had received a message from McCain via South Carolina senator Lindsay Graham, a close friend. The senator told them he was eager to “get back and get to work”, Hoeven added.

Graham was visibly emotional as he recalled his conversation with McCain when he learned of the diagnosis.

“He says, 'I've been through worse',” Graham told reporters. Five minutes into the call, however, McCain wanted to talk the legislative priories, Graham said.

“God knows how this ends,” he said. “But I do know this: This disease has never had a more worthy opponent.”

In a statement, McCain's daughter Meghan said: “He is a warrior at dusk, one of the greatest Americans of our age, and the worthy heir to his father's and grandfather's name. But to me, he is something more. He is my strength, my example, my refuge, my confidante, my teacher, my rock, my hero – my Dad.”</s>Republican Senator John McCain, who is the chairman of the powerful Senate Armed Services Committee, has been diagnosed with brain cancer, Mayo Clinic hospital has said.

The tumour was diagnosed after McCain, who was the Republican presidential candidate in 2008 elections, underwent a procedure to remove a blood clot from his left eye.

According to the Mayo Clinic Hospital in Phoenix, McCain underwent a procedure to remove a blood clot from above his left eye at the hospital on July 14.

Subsequent tissue pathology revealed that a primary brain tumour known as a glioblastoma was associated with the blood clot, the hospital said in a statement yesterday.

Scanning done since the procedure (a minimally invasive craniotomy with an eyebrow incision) shows that the tissue of concern was completely resected by imaging criteria, it said.

"The Senator and his family are reviewing further treatment options with his Mayo Clinic care team. Treatment options may include a combination of chemotherapy and radiation. The Senator's doctors say he is recovering from his surgery 'amazingly well' and his underlying health is excellent.", the hospital said in a statement.

In a statement issued by his office, McCain appreciated the outpouring of support he has received over the last few days.

"He is in good spirits as he continues to recover at home with his family in Arizona. He is grateful to the doctors and staff at Mayo Clinic for their outstanding care, and is confident that any future treatment will be effective. Further consultations with Senator McCain's Mayo Clinic care team will indicate when he will return to the United States Senate," the office said.

McCain, who was re-elected to his sixth term in the Senate in 2016, served as an aviator in the US navy before entering politics. He was held as prisoner of war for five and a half years during the Vietnam war
U.S. Senator John McCain is diagnosed with a malignant brain cancer, glioblastoma multiforme. This is his second battle with cancer, after having been successfully treated for malignant melanoma.