Gallium Ga 68 FAPI-46
Gallium Ga 68 FAPi-46 is a radioconjugate composed of FAPi-46, a quinoline-based fibroblast activation protein (FAP)-targeted tracer belonging to the group of FAP inhibitors (FAPi), conjugated to the radioisotope gallium Ga 68, with potential use as a tracer for FAP-expressing tumors during positron emission tomography (PET). Upon administration of gallium Ga 68 FAPi-46, the FAPi-46 moiety targets and binds to FAP-expressing tumor cells. Upon binding, FAP-expressing tumor cells can be detected during PET imaging. FAP, a cell surface protein, is overexpressed in a wide variety of cancer cell types.