text: SECTION 1. SHORT TITLE.
  
      This Act may be cited as the ``National Childhood Brain Tumor 
  Prevention Network Act of 2008''.
  
  SEC. 2. FINDINGS.
  
      Congress finds the following:
              (1) Tumors kill more children than any other disease and 
          brain tumors are the second most common type of cancer in 
          children.
              (2) Childhood brain tumors are the leading cause of death 
          from solid tumors in children.
              (3) There are newly recognized types of brain tumors, as 
          defined by the World Health Organization, and many of these 
          newly recognized types occur in children.
              (4) The causes of the overwhelming majority of childhood 
          brain tumors are unknown.
              (5) Brain tumors have substantial costs for affected 
          children, the families of such children, and society.
              (6) Childhood brain tumors cause significant morbidity and 
          the loss of many years of potential life.
              (7) The prognosis for most childhood brain tumors is dismal 
          and survivors face lasting adverse health effects.
              (8) Because of the relatively low overall incidence of 
          childhood brain tumors, such tumors frequently do not receive 
          sufficient attention and research funding.
              (9) No single institution has a sufficient number of 
          patients to independently conduct research that will adequately 
          address the causes of childhood brain tumors.
              (10) There has been no comprehensive study analyzing all 
          relevant clinical, biological, and epidemiological aspects of 
          childhood brain tumors to identify potential risk factors and 
          determine the cause of such tumors.
              (11) Existing national cooperative clinical oncology groups 
          primarily investigate treatment options and prognosis and do 
          not typically examine the origins of childhood brain tumors or 
          the risk factors associated with such tumors. A significant 
          majority of children with brain tumors are first treated by 
          neurosurgeons and not by oncologists typically involved in such 
          groups.
  
  SEC. 3. SENSE OF CONGRESS.
  
      It is the sense of Congress that--
              (1) there is a need to establish a multi-center research 
          effort based on collaboration between regional consortia in 
          order to comprehensively study the causes of childhood brain 
          tumors and identify potential risk factors;
              (2) there is a need to encourage a collaborative effort 
          among surgical and medical centers with epidemiological study 
          groups to gather comprehensive and detailed information for 
          each child enrolled in those groups, in order to investigate 
          environmental, nutritional, genetic, and developmental factors 
          with respect to, and the pathological and epidemiological 
          characteristics of, childhood brain tumors; and
              (3) there is a need to authorize the Director of the 
          National Institutes of Health to coordinate national research 
          efforts of governmental and nongovernmental entities with 
          respect to childhood brain tumors.
  
  SEC. 4. ESTABLISHMENT OF THE NATIONAL CHILDHOOD BRAIN TUMOR PREVENTION 
                NETWORK.
  
      (a) In General.--Subpart 1 of part C of title IV of the Public 
  Health Service Act (42 U.S.C. 285 et seq.) is amended by adding at the 
  end the following:
  
  ``SEC. 417F. NATIONAL CHILDHOOD BRAIN TUMOR PREVENTION NETWORK.
  
      ``(a) Establishment of the National Childhood Brain Tumor 
  Prevention Network.--
              ``(1) In general.--Not later than one year after the date 
          of the enactment of this section, the Director of NIH, acting 
          through the Director of the National Cancer Institute, shall 
          establish, administer, and coordinate a National Childhood 
          Brain Tumor Prevention Network (hereinafter referred to in this 
          section as the `Network') for the purposes described in 
          paragraph (2).
              ``(2) Purposes.--The purposes of the Network shall be the 
          following:
                      ``(A) Providing grants of not fewer than five years 
                  duration to eligible consortia for the purpose of 
                  conducting research with respect to the causes of and 
                  risk factors associated with childhood brain tumors.
                      ``(B) Assembling a panel of experts, including 
                  members of the Brain Tumor Epidemiology Consortium and 
                  survivors of brain tumors, to provide ongoing guidance 
                  and recommendations for, with respect to research 
                  funded by the Network, the development of the 
                  following:
                              ``(i) A common study design.
                              ``(ii) Standard protocols, methods, 
                          procedures, and assays for collecting from 
                          individuals enrolled as study participants, and 
                          the parents of such individuals, a minimum data 
                          set that includes the following:
                                      ``(I) Environmental exposure data.
                                      ``(II) Nutritional data.
                                      ``(III) Biospecimens, including 
                                  genomic data.
                                      ``(IV) Histopathological and 
                                  molecular pathological data and 
                                  specimens.
                                      ``(V) Clinical and radiological 
                                  data.
                              ``(iii) Specific analytical methods for 
                          examining data.
                              ``(iv) Provisions for consensus review of 
                          enrolled cases.
                              ``(v) An integrated data collection 
                          network.
                      ``(C) Designating a central laboratory to collect, 
                  analyze, and aggregate data with respect to research 
                  funded by the Network and to make such data and 
                  analysis available to researchers.
              ``(3) Eligible consortia.--To be eligible for a grant under 
          this section, a consortium shall demonstrate the following:
                      ``(A) The capability to annually enroll as research 
                  participants a minimum of 100 individuals with a newly 
                  diagnosed childhood brain tumor from the designated 
                  catchment area of such consortium.
                      ``(B) The capability to form a control group by 
                  enrolling as research participants, for each enrolled 
                  individual with a childhood brain tumor, at least two 
                  individuals without a childhood brain tumor, who are 
                  matched demographically to such enrolled individual 
                  with a childhood brain tumor.
                      ``(C) That the designated catchment area of such 
                  consortium does not overlap with the designated 
                  catchment area of a consortium already receiving a 
                  grant under this section.
              ``(4) Report.--Not later than one year after the date of 
          the enactment of this section and annually thereafter, the 
          Director of NIH shall submit to Congress a report with respect 
          to the Network, to be made publicly available, including a 
          summary of research funded by the Network and a list of 
          consortia receiving grants under the Network. At the discretion 
          of the Director of NIH, such report may be combined with other 
          similar or existing reports.
              ``(5) Authorization of appropriations.--
                      ``(A) In general.--There is authorized to be 
                  appropriated $25,000,000 for each of fiscal years 2010 
                  through 2014, to remain available until expended, to 
                  carry out this section.
                      ``(B) Sense of congress.--It is the sense of 
                  Congress that funds appropriated to carry out this 
                  section should be in addition to the funds already 
                  appropriated to carry out the functions of the National 
                  Institutes of Health.
      ``(b) Definitions.--For purposes of this section, the following 
  definitions apply:
              ``(1) Brain tumor epidemiology consortium.--The term `Brain 
          Tumor Epidemiology Consortium' means the organization with such 
          name formed in 2003 after an initial meeting sponsored by the 
          National Cancer Institute's Division of Cancer Epidemiology and 
          Genetics.
              ``(2) Catchment area.--The term `catchment area' means a 
          defined area for which population data are available.
              ``(3) Childhood brain tumor.--The term `childhood brain 
          tumor' means an intracranial or spinal cord tumor occurring in 
          an individual under 20 years of age.
              ``(4) Consortium.--The term `consortium' means a 
          partnership of two or more universities, health care 
          organizations, or government agencies, or any combination of 
          such entities, serving a designated catchment area.''.
      (b) Technical Correction.--
              (1) In general.--Section 3 of the Hematological Cancer 
          Research Investment and Education Act of 2002 (Public Law 107-
          172; 116 Stat. 541) is amended by striking ``419C'' and 
          inserting ``417C''.
              (2) Effective date.--The amendment made by paragraph (1) 
          shall take effect as if included in the enactment of the Act 
          referred to in such paragraph.
target: National Childhood Brain Tumor Prevention Network Act of 2008 - Amends the Public Health Service Act to require the Director of the National Institutes of Health (NIH), acting through the Director of the National Cancer Institute, to establish, administer, and coordinate a National Childhood Brain Tumor Prevention Network to: (1) provide grants for research on the causes of and risk factors associated with childhood brain tumors; (2) assemble a panel of experts to provide ongoing guidance and recommendations on research funded by the Network, including on a common study design and standard protocols; and (3) designate a central laboratory to collect, analyze, and aggregate data with respect to research funded by the Network and to make such data and analysis available to researchers.
feat_title: To amend title IV of the Public Health Service Act to create a National Childhood Brain Tumor Prevention Network to provide grants and coordinate research with respect to the causes of and risk factors associated with childhood brain tumors, and for other purposes.