Boca Juniors set up a mouthwatering Copa Libertadores last-16 clash with fierce rivals River Plate after a 2-0 victory over Palestino to finish Group Five with a 100 per cent winning record. Leandro Marin headed the Argentinian giants into the lead in the final minute but a lengthy delay in the second half meant there was a significant amount of injury time, with Jonatan Calleri sealing all three points in the 11th minute of time added on. Victory over their Chilean opponents ensured Boca finish as the highest seeds of the competition - with no other teams winning all of their group games - while no second placed team can finish on less points than River. VIDEO Scroll down to watch Copa Libertadores Highlights: Boca Juniors 2-0 Palestino . Leandro Marin (left) gave Boca Juniors the lead with a headed finish in the final minute . Boca scored another late goal in injury time as they secured a 2-0 victory against Chilean side Palestino . Rodolfo Arruabarrena's side will now face arch rivals River Plate in the Copa Libertadores last 16 . It sets up a Superclasico date and Boca boss Rodolfo Arruabarrena said: 'It will be tough and exhausting. We are confident in our team and we will try to do things right to go on in the cup.' Wanderers also sealed their place in the last-16 after cruising to a 3-0 victory at Zamora to finish second, behind Boca, in the group. Matias Santo opened the scoring in the 34th minute for the Uruguayan visitors, while Nicolas Albarracin doubled their lead just after the hour mark before Gaston Rodriguez made sure there was no way back for their Venezuelan hosts. River Plate kept alive their cup dream with a 3-0 victory over Bolivian side San Jose on Wednesday . Internacional thumped Universidad de Chile 4-0 to go top of Group Four with one round to go. Nilmar opened the scoring in the ninth minute and then added another just after the half hour after Eduardo Sasha had doubled the Brazilian side's lead, with Valdivia sealing a comfortable win on the hour. Brazilian outfit Corinthians made sure of top spot in Group Two following a goalless draw with reigning champions San Lorenzo, who sit third and must hope they beat Danubio next week and Corinthians beat Sao Paulo. Brazilian international Nilmar scored for Internacional as they thumped Universidad de Chile 4-0 .
Boca Juniors defeated Palestino 2-0 with two late second-half goals .
Leandro Marin and Jonatan Calleri were both on the scoresheet .
Boca now face arch rivals River Plate in the Copa Libertadores last 16 .