As akshan, This is the phase of the game where you will be dealing a ton of damage. You can use your E more liberally to get some kills from now on.

Your Ultimate will be on a short cooldown, so ensure that you use it quite frequently. It will definitely help you with chunking out enemies who have already taken some damage.

If you have allies who have CC built into their kit, try to stick near them. You should always focus on the CC'd target and kill them when you get a chance. Also, if the enemy has an assassin, try to shadow them and see if you can get the kill on them if they assassinate your allies. As akshan, You can use your E more liberally to get murders from now on. Your Ultimate will be on a short cooling time, to make sure you use it quite frequently. It will certainly help you cut off enemies who have already taken damage. If you have allies who have CC integrated into their kit, try to stay close to them. You should always focus on target CC'd and kill them when you get a chance. Also, if the enemy has a murderer, try to shade them and see if you can get the murder on them if they assassinate your allies.