Against sett, When playing as a ranged mid-laner, try your hardest to harass and poke him down while staying at the maximum distance as possible so he is unable to E you.

Avoid extended trades with Sett early. He has a lot of physical damage and will win most auto-attack trades. Keep this in mind when trading with him.

At level 6, Sett’s Ultimate R is pretty strong. Do not overextend or stay on low health in the lane as he can easily kill you or set up his Jungler. Against sett, When you play as a varied mid-laner, try your hardest to harass and push it down while remaining at the maximum possible distance so it is incapable of you E. Avoid prolonged trading with Sett early. It has a lot of physical damage and will win most self-attack trading. Keep this in mind during trading with it. At level 6, Setts Ultimate R is strong enough. Don't overextend or stay on bad health in the way it can easily kill you or set up its Jungler.