Against vladimir, Vladimir’s l has an incredibly long cooldown during the laning phase. Find a way to bait it out and then look to play aggressive while it’s on cooldown.

Whenever Vladimir has his empowered Q available, play safer or walk backwards so he is forced to use his Q on the minion wave rather than you.

When playing as an AD champion, try to get an Executioner’s Calling. This will reduce his healing and sustain in lane.  Against vladimir, Vladimir's l has an incredibly long cooldown during the laning phase. Find a way to bait him and then watch to play aggressive while he's on cooldown. Whenever Vladimir has his self-appointed Q available, play safer or walk backwards so he is forced to use his Q on the minion wave rather than you.