Lafikun, ati safihan re pe idabobo-ara ti abere ajesara n sokunfa lodo awon olufarajin eniyan ni o ni iyasoto iporo ti a danwo.Eto Meji si meta ilo oogun ni a gbaniyanju leyi ti o da lori irufe.. 
Aldehyde dehydrogenase 16 family, member A1 tí a tún mọ̀ sí  ALDH16A1 jẹ́ aldehyde dehydrogenase gene.ÌWÚLÒ rẹ̀ FÚN ètò ìleraàwọn ìyípadà nínú SPG21  (ACP33/maspardin) gene ní ìbáṣepọ̀ pẹ̀lú mast syndrome, tí ó jẹ́ irú  spastic paraplegia.. 