Ni odun 1965, o fe arabirin Hazel Mae Guadreau, ti o koko wa lati Gloucester; Hazel kawe ni  Boston University, nibi ti o ti ko eko ijo, ohun ati orin.. 
Ní ìmọ̀ àrùn opolo,  bàbà anion ti glutamate jẹ́ ohun tí ó maa ń fún  neurotransmitter lágbára lati sise itaji àwọn ètò opolo.. 