ELECTRONIC	h   t   t   p   c o l o n   s l a s h   s l a s h   w   w   w dot c y t e l dot c o m   s l a s h   p a p e r s   s l a s h   t w o b i n o m i a l s dot p d f b a r n a r d	http://www.cytel.com/papers/twobinomials.pdfbarnard	1