In software engineering, relying on experience can render maintainability expertise into prejudice over time. For example, based on their own experience, some consider JavaScript as inelegant language and hence of lowest maintainability. Such prejudice should not guide decisions without prior empirical validation.
 What is the effect of programming languages on software quality? This question has been a topic of much debate for a very long time. In this study, we gather a very large data set from GitHub (728 projects, 63 million SLOC, 29,000 authors, 1.5 million commits, in 17 languages) in an attempt to shed some empirical light on this question. This reasonably large sample size allows us to use a mixed-methods approach, combining multiple regression modeling with visualization and text analytics, to study the effect of language features such as static versus dynamic typing and allowing versus disallowing type confusion on software quality. By triangulating findings from different methods, and controlling for confounding effects such as team size, project size, and project history, we report that language design does have a significant, but modest effect on software quality. Most notably, it does appear that disallowing type confusion is modestly better than allowing it, and among functional languages, static typing is also somewhat better than dynamic typing. We also find that functional languages are somewhat better than procedural languages. It is worth noting that these modest effects arising from language design are overwhelmingly dominated by the process factors such as project size, team size, and commit size. However, we caution the reader that even these modest effects might quite possibly be due to other, intangible process factors, for example, the preference of certain personality types for functional, static languages that disallow type confusion. Programming languages have been proposed even before the era of the modern computer. As years have gone, computer resources have increased and application domains have expanded, leading to the proliferation of hundreds of programming languages, each attempting to improve over others or to address new programming paradigms. These languages range from procedural languages like C, object-oriented languages like Java, and functional languages such as ML and Haskell. Unfortunately, there is a lack of large scale and comprehensive studies that examine the "popularity", "interoperability", and "impact" of various programming languages. To fill this gap, this study investigates a hundred thousands of open source software projects from GitHub to answer various research questions on the "popularity", "interoperability" and "impact" of various languages measured in different ways (e.g., in terms of lines of code, development teams, issues, etc.).