The Encoder-Decoder architecture is a main stream deep learning model for biomedical image segmentation. The encoder fully compresses the input and generates encoded features, and the decoder then produces dense predictions using encoded features. However, decoders are still under-explored in such architectures. In this paper, we comprehensively study the state-of-the-art Encoder-Decoder architectures, and propose a new universal decoder, called cascade decoder, to improve semantic segmentation accuracy. Our cascade decoder can be embedded into existing networks and trained altogether in an end-to-end fashion. The cascade decoder structure aims to conduct more effective decoding of hierarchically encoded features and is more compatible with common encoders than the known decoders. We replace the decoders of state-of-the-art models with our cascade decoder for several challenging biomedical image segmentation tasks, and the considerable improvements achieved demonstrate the efficacy of our new decoding method.
Accurate localization and segmentation of intervertebral discs (IVDs) from volumetric data is a pre-requisite for clinical diagnosis and treatment planning. With the advance of deep learning, 2D fully convolutional networks (FCN) have achieved state-of-the-art performance on 2D image segmentation related tasks. However, how to segment objects such as IVDs from volumetric data hasn’t been well addressed so far. In order to resolve above problem, we extend the 2D FCN into a 3D variant with end-to-end learning and inference, where voxel-wise predictions are generated. In order to compare the performance of 2D and 3D deep learning methods on volumetric segmentation, two different frameworks are studied: one is a 2D FCN with deep feature representations by making use of adjacent slices, the other one is a 3D FCN with flexible 3D convolutional kernels. We evaluated our methods on the 3D MRI data of MICCAI 2015 Challenge on Automatic Intervertebral Disc Localization and Segmentation. Extensive experimental results corroborated that 3D FCN can achieve a higher localization and segmentation accuracy than 2D FCN, which demonstrates the significance of volumetric information when confronting 3D localization and segmentation tasks.