Accurate multi-organ abdominal CT segmentation is essential to many clinical applications such as computer-aided intervention. As data annotation requires massive human labor from experienced radiologists, it is common that training data are partially labeled, e.g., pancreas datasets only have the pancreas labeled while leaving the rest marked as background. However, these background labels can be misleading in multi-organ segmentation since the "background" usually contains some other organs of interest. To address the background ambiguity in these partially-labeled datasets, we propose Prior-aware Neural Network (PaNN) via explicitly incorporating anatomical priors on abdominal organ sizes, guiding the training process with domain-specific knowledge. More specifically, PaNN assumes that the average organ size distributions in the abdomen should approximate their empirical distributions, a prior statistics obtained from the fully-labeled dataset. As our training objective is difficult to be directly optimized using stochastic gradient descent [20], we propose to reformulate it in a min-max form and optimize it via the stochastic primal-dual gradient algorithm. PaNN achieves state-of-the-art performance on the MICCAI2015 challenge "Multi-Atlas Labeling Beyond the Cranial Vault", a competition on organ segmentation in the abdomen. We report an average Dice score of 84.97 , surpassing the prior art by a large margin of 3.27 .
Convolutional networks are powerful visual models that yield hierarchies of features. We show that convolutional networks by themselves, trained end-to-end, pixels-to-pixels, exceed the state-of-the-art in semantic segmentation. Our key insight is to build “fully convolutional” networks that take input of arbitrary size and produce correspondingly-sized output with efficient inference and learning. We define and detail the space of fully convolutional networks, explain their application to spatially dense prediction tasks, and draw connections to prior models. We adapt contemporary classification networks (AlexNet [20], the VGG net [31], and GoogLeNet [32]) into fully convolutional networks and transfer their learned representations by fine-tuning [3] to the segmentation task. We then define a skip architecture that combines semantic information from a deep, coarse layer with appearance information from a shallow, fine layer to produce accurate and detailed segmentations. Our fully convolutional network achieves state-of-the-art segmentation of PASCAL VOC (20 relative improvement to 62.2 mean IU on 2012), NYUDv2, and SIFT Flow, while inference takes less than one fifth of a second for a typical image.  Scene parsing is challenging for unrestricted open vocabulary and diverse scenes. In this paper, we exploit the capability of global context information by different-region-based context aggregation through our pyramid pooling module together with the proposed pyramid scene parsing network (PSPNet). Our global prior representation is effective to produce good quality results on the scene parsing task, while PSPNet provides a superior framework for pixel-level prediction. The proposed approach achieves state-of-the-art performance on various datasets. It came first in ImageNet scene parsing challenge 2016, PASCAL VOC 2012 benchmark and Cityscapes benchmark. A single PSPNet yields the new record of mIoU accuracy 85.4 on PASCAL VOC 2012 and accuracy 80.2 on Cityscapes. Multiple instance learning (MIL) can reduce the need for costly annotation in tasks such as semantic segmentation by weakening the required degree of supervision. We propose a novel MIL formulation of multi-class semantic segmentation learning by a fully convolutional network. In this setting, we seek to learn a semantic segmentation model from just weak image-level labels. The model is trained end-to-end to jointly optimize the representation while disambiguating the pixel-image label assignment. Fully convolutional training accepts inputs of any size, does not need object proposal pre-processing, and offers a pixelwise loss map for selecting latent instances. Our multi-class MIL loss exploits the further supervision given by images with multiple labels. We evaluate this approach through preliminary experiments on the PASCAL VOC segmentation challenge.  Recent leading approaches to semantic segmentation rely on deep convolutional networks trained with human-annotated, pixel-level segmentation masks. Such pixel-accurate supervision demands expensive labeling effort and limits the performance of deep networks that usually benefit from more training data. In this paper, we propose a method that achieves competitive accuracy but only requires easily obtained bounding box annotations. The basic idea is to iterate between automatically generating region proposals and training convolutional networks. These two steps gradually recover segmentation masks for improving the networks, and vise versa. Our method, called "BoxSup", produces competitive results (e.g., 62.0 mAP for validation) supervised by boxes only, on par with strong baselines (e.g., 63.8 mAP) fully supervised by masks under the same setting. By leveraging a large amount of bounding boxes, BoxSup further yields state-of-the-art results on PASCAL VOC 2012 and PASCAL-CONTEXT [26]. Semantic segmentation has been a long standing challenging task in computer vision. It aims at assigning a label to each image pixel and needs a significant number of pixel-level annotated data, which is often unavailable. To address this lack of annotations, in this paper, we leverage, on one hand, a massive amount of available unlabeled or weakly labeled data, and on the other hand, non-real images created through Generative Adversarial Networks. In particular, we propose a semi-supervised framework – based on Generative Adversarial Networks (GANs) – which consists of a generator network to provide extra training examples to a multi-class classifier, acting as discriminator in the GAN framework, that assigns sample a label y from the K possible classes or marks it as a fake sample (extra class). The underlying idea is that adding large fake visual data forces real samples to be close in the feature space, which, in turn, improves multiclass pixel classification. To ensure a higher quality of generated images by GANs with consequently improved pixel classification, we extend the above framework by adding weakly annotated data, i.e., we provide class level information to the generator. We test our approaches on several challenging benchmarking visual datasets, i.e. PASCAL, SiftFLow, Stanford and CamVid, achieving competitive performance compared to state-of-the-art semantic segmentation methods. Deep convolutional neural networks (CNNs) are the backbone of state-of-art semantic image segmentation systems. Recent work has shown that complementing CNNs with fully-connected conditional random fields (CRFs) can significantly enhance their object localization accuracy, yet dense CRF inference is computationally expensive. We propose replacing the fully-connected CRF with domain transform (DT), a modern edge-preserving filtering method in which the amount of smoothing is controlled by a reference edge map. Domain transform filtering is several times faster than dense CRF inference and we show that it yields comparable semantic segmentation results, accurately capturing object boundaries. Importantly, our formulation allows learning the reference edge map from intermediate CNN features instead of using the image gradient magnitude as in standard DT filtering. This produces task-specific edges in an end-to-end trainable system optimizing the target semantic segmentation quality. Deep convolutional neural networks (DCNNs) trained on a large number of images with strong pixel-level annotations have recently significantly pushed the state-of-art in semantic image segmentation. We study the more challenging problem of learning DCNNs for semantic image segmentation from either (1) weakly annotated training data such as bounding boxes or image-level labels or (2) a combination of few strongly labeled and many weakly labeled images, sourced from one or multiple datasets. We develop Expectation-Maximization (EM) methods for semantic image segmentation model training under these weakly supervised and semi-supervised settings. Extensive experimental evaluation shows that the proposed techniques can learn models delivering competitive results on the challenging PASCAL VOC 2012 image segmentation benchmark, while requiring significantly less annotation effort. We share source code implementing the proposed system at this https URL   