Father Jofré defending a madman is an oil on canvas painting by Joaquín Sorolla painted in Assisi in 1887 and owned by the Provincial Council of Valencia, but exhibited in storage at the Palace of the Generalitat of Valencia. It is a work from his formative stage, painted during his stay in Italy between 1885 and 1889 thanks to a scholarship from the Provincial Council of Valencia to train at the Spanish Academy of Fine Arts in Rome. The painting was a requirement of the scholarship and its submission allowed him to extend the scholarship for one year in 1888.1​2​3​4​ During his stay in Assisi he met Emilio Sala, who influenced Sorolla's style when painting this work.5​

The work shows a scene that occurred on February 24, 1409, in which Father Jofré, a Valencian Mercedarian friar, defends a young man with psychiatric problems from a crowd when he was on his way to give the sermon on the first Sunday of Lent to the cathedral of Valencia. Through the speech he gave in response to this e