Hi Don, It is a known issue, apprently.  As you know VSM is a Linux box and the schedules are totally nonsensical unless the machine the browser is run from are in US region and format, and also the region added to the end of the URL.  I have changed the vcentre servers to US Region, used xxxxxx/vsphere-client and it now works.  Before when you add a new datastore and use a template schedule it doesn’t refer to the system locale and adds it OK, but you can’t change it.  Now I can create and change at will, however I have to go on to the server to do it as I am not changing my laptop to US region.
I have two customers now that have VSM 4.0.2.1 Both have complained that after initially specifying a replication schedule this can't be modified later. In addition new schedules can;t be created. Is this a known bug and is there a workaround please? 
Can't alter VSM replication schedule