No, VPLEX and RM integration does not currently exist.
I just migrated our entire Accounting system to VPLEX.  I should say encapsulated all storage since there is a difference.  However, Replication Manager is NOT working anymore.  It basically states that the source LUNs are on an unsupported array.  I can't find any documentation if RM is even supported or if it even works on VPLEX.  Not sure if this is the proper place to even post this question.  Thanks,  Damian
Does Replication Manager work with VPLEX?