Keep it updated, make certain all your AW peripherals are correctly configured so that they are recognized by AWCC. Scan your system so that all installed games are recognized and added to the library. Then set up your profiles as necessary...set RGB lighting, fan curves, and any other overclock settings needed. I have separate profiles for my various games. My lighting profiles reflect the games, for example, setting the keyboard lighting so that it highlights useful keys. In most MMOs, I have the WASD movement keys lit in red, so I can get to them quickly.
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DS 07/21: How to get the most out of the Alienware Command Center?