The results will be about the same as if you had a 5,000 pound trailer and want to tow it with a Toyota Camry. If you're in need of high-end graphics and heavy use, there are Alienware and Precision notebooks.   If you need a mid-range system, there are Latitude notebooks. You need to decide which is more important - performance or system cost;  you're going to be compromising somewhere.  And if your budget won't stretch to a high-end Alienware or Precision notebook, there is the option of a desktop system -- where you get twice the performance for your dollar (or whatever currency you choose).  
What middle-end laptop will be good for high-end graphics and heavy operational use?
High-end graphics and heavy operational use