You could, please refer to the release notes and the scale document. Many of the limits of RP4VM are at the vCenter level  (# of VMs / # of ESX servers / # of vRPA clusters)  I would recommend using the 2 that you have vs 1.
Hi,   I want  to securise 2 local campus DC replicated with rp for vm CRR (sync)  and an third site with rp for vm (crr async). Do I need 3 vCenter ? Can I have a single vcenter for 2 locals DC and second one on the third site ?  thanks Regards, Benoit
Number of vcenter needed