I am not sure it will migrate the system LUNs. It isn’t supported so it is at your own risk to try it. 
Is it possible to replace the first 4 drives in a VNX 5200?  They are 300GB and I would like to swap out for 1.2TB drives.  Actually, I plan to replace them for the entire enclosure.  There are other DAE's attached for me to swing existing data to, but is that necessary or can I replace them  one-by-one if they are unbound? Again though, I'm more concerned about how to handle the first four drives.  Is there a documented process for this? Disclaimer, I am new to EMC storage and this system is being used for a development project. Thank you!
VNX 5200 Replace Drives 0-3 with Larger Drives?