Always include exact PC model in your posts... SD card readers are USB devices so, for starters: Let us know if that helps. If not, there are other power plan settings you may have to change...  
All in One, Win 10 Pro When inserting a SD Micro card Windows 10 doesn't recognize a card has been inserted. But using Device Manager and then Scan for Hardware Changes the device is found and works UNTIL you remove it and insert another micro card (actually it may work for more than one but at some point its going to quit working). Starting Device Manager and Scan for H/W changes works. The user is not willing to do these few steps. In Device Manager are SD Card readers listed under "Storage Controllers"?  I do not have a Memory listing in Device Manager that I saw on another post.  Should I disable the drivers, delete, and then let Windows refind the device. Would getting a USB card read be the easiest way.   $20 from Amazon. Thanks for any ideas.  This machine is used for probably 5 SD cards a week but they are vital to workflow. Thanks again.  
All In One - SD Micro Card Reader - Works sometimes and others can't be found 
until you used Device Manager to kick it