A high speed data cable is not enough (I tried). The issue is USB-C Alt mode. There are plenty of cables that go from USB-C to DisplayPort. There are none that go the other way. So I'm going with switches on the display port cables (2 in, 1 out) on the main two monitors and two different connections on the third shared monitor (HDMI to VGA from the desktop, HDMI to HDMI from the dock). If my work decides to ever upgrade the work laptop or desktop, they will have the capacity to leverage the docking station.  
I bought a UD22 and it works great with my personal laptop, which has a USB-C output port. But I am working from home and also want to hook up legacy machines that do not have USB-C. One is an old Precision 3420 desktop which has two DisplayPort and one HDMI output. The other is Latitude E7450 which works with the D6000 using the USB-C to USB adapter that comes with it. I cannot find any adapters that outputs to USB-C with video (from DP, HDMI, or USB 2/3).  Has anyone found a solution to this?  I can get three monitors running directly off the desktop and four from my personal laptop through the UD22. I would prefer not to have to keep switching cables every time I want to switch machines.  
Using UD22 Dock with older desktop (USB-C output with video)