Thanks to user Hotel Bravo who found this workaround. I've found a solution! Well, sort of -- it's a workaround, but it solves the issue.        
  Hi! Same here with  DDM 2.0.0.138. and Dell U3223QE. I've gone through all Settings and can't find Alt + S shortcut. This shortcut is very important to me so I can't use DDM, which is bad. Please fix this.Thanks.
U3223QE, DDM 2.0, taking Alt + S shortcut, #2