Hello Olainen, If it was me doing your deployment I would go with your second option.  As you stated that if you go with option 1 then you will have limited performance, as all is being done through a single controller.  Here is also a link to Dell EMC PowerVault ME4 Series and VMware vSphere best practices. [URL]
Does anyone have a (justified) recommendation for disk configuration on an ME4024 consisting of In short, I think my two best options are either: The ME4024 is connected with SAS to two R640 ESXi hosts (works perfect since VMFS is cluster aware). The two hosts will run around 30 VMs between themselves with light load.
ME4024 - To tier or cache with SSD (with 2 ESXi hosts)?