In a matter of speaking the end-effect is the same, VSAN's cannot be reached or connected. VSAN isolation generally means, the VSAN cannot be used like VSAN 4094 or is excluded from connectivity. Segmentation generally means two VSAN's (same numbers) cannot connect thru ISL's, due to ISL incompatability, security, unallowed (non-trunked) VSAN's or overlapping domains parameters. Isolation is generally configured on purpose while segmentation is mostly caused due to poor configuration.  Kind Regards,  Peter Ooms CCIE#28567 SAN
Hi,  I am new to Cisco. Could any one tell me whats the difference between vsan segmentation and vsan isolation ? 
vsan segmentation and vsan isolation