The 5080 only supports an M.2 NVMe SSD. In addition, of course, to 2.5" and 3.5" drives as per the spec sheet here. So the answer is no SATA and only NVMe.
Does a Dell Optiplex 5080 SFF support an M.2 SATA SSD, or only an M.2 NVME SSD? I know the 3080 does not support M.2 SATA SSD, but what about the 5080? Please don't ask for my Service TAG in private message, I don't have the 5080 yet.
Dell Optiplex 5080 SFF M.2 SATA SSD support?