Joe, All I can say is that protection is enabled for me in EDGE on two separate Win10 systems. Did you try first disabling all protection, then following with enable all protection?   Just a thought. P.S.  The kudo was accidental.
SpywareBlaster database update 10/4/20226 NEW items (IE/ActiveX)11 NEW items (Edge/Scripts)for a total of 18,823 items in databaseAfter updating, be sure to manually enable all protection.  
Updates 10/4/22 - SpywareBlaster