To be honest I am not sure either it is coming from Outlook or vWorkspace.  I have added a screenshot of the error hoping that may help. Going through the Web Access page it does start to load Outlook at when it gets to the loading profile it stops.   If I login to a console to the TS server it loads fine.  It does take me through the manual setup of the mail profile but it works.  Also, using the vworkspace RD client, if I RD directly into the TS it does the same as logging into the console, but if switch from Server to Application and go through the CB i get the same error that I do on the Web Access page.  [IMAGE]
I am creating Windows Server 2008 R2 environment with vWorkspace 7.2 MR1.  I have installed Office 2010 on the terminal server.  We like to use a PRF file to configure Outlook for our users.  When I launch Outlook directly from the TS server it open without issue.  If I launch Outlook through Web Access (we do not use the AppPortal) or use the Quest RD client going through the Connection Broker I get the following error when it goes through the profile creation.  The Server is unavailable   All servers in the environement are inside the firewall. I can ping the exchange server from the Connection Broker.   I can launch Word from the Web Access page.  So there are apps that do work.  
Trouble with Outlook 2010 when launched through Connection Broker