Thank you for your help.  The issue was that VMware Shared Folders was installed on the TS Server keeping the folder locked.  I reinstalled VMware tools with the typical installation and I am now able to log off/delete the profiles and now the Outlook profile is being captured in the metaprofile.  
I have an application that needs access to a mail profile in Windows to email out of the application. We are using Exchange 2007 right now (we will be upgrading later this year to 2010). This profile would also need to be used for Outlook 2010.  I have Windows 2008 R2 servers running vWorkspace 7.2. MR1.   In my old Server 2003/vWorkspace 7.1 environment we used a VBS script that called a PRF.  This script and PRF do not seem to work right in Windows 2008/Office 2010 setup.  Does anyone know the best way to do this?
Outlook mail profile other applications can access