Nope. Only the III boards will support 5400-series processors.
Does the motherboard of a Poweredge 1950 Gen I support a CPU swap from the Xeon 5060 to a Xeon X5450? I know the Gen III's support that CPU but is it possible to put one in the first generation without a board swap?
Poweredge 1950 Gen I with a Xeon X5450?