Yes... M.2 is very popular in PeeCee'isch like devices like Workstation, OfficePC and Laptops or PS5  Just grab the first PCIe card which you can get and try it. Note: Server normaly use fan less PCIe devices without active cooling because when its a CARD from the server vendor the inventory holds voltage and cooling information so that the server fans can deliver propper colling.If you use 3rd. party stuff expect different behaviour or just chosse a different performance profile. Our M.2 NVME drives use a heatsink for example.
Dear Dell I am getting misinformation from your sales staff in Hong Kong. I am a corporate (education) customer and I just bought a PowerEdge R650. Simply, I want to add M.2 NVME drives which are standard and easy to find nowadays to my machine. They refuse to provide a quote, despite me simply asking for the rearbay configuration.  This has gone on for weeks. They are slow to respond, do not call back, and do not communicate clearly. I understand HK is not the biggest market for corporate servers, but it is impossible to reach Dell's support staff in the US for very simple basic questions.
PowerEdge R650, staff in Hong Kong are frustrating