I had this happening on two E6410s that I have so glad I came across this post.  At one point, likely before 1709 this was not a problem.  Although, I am not certain for sure as that was some time ago.  In any event, I just backed up the data, wiped and reloaded with NON-UEFI setup thus eliminated the GPT setup and went legacy MBR.  Both are now running latest 20H2 fully patched with all drivers updated.  Seems whatever was part of the problem must be a bug somewhere that causes this issue.  In any event, they are running like champs now as they are not bad systems for surfing the web.  Setup running Office 2013 on both with Edge, Brave, and Firefox. Both are running 2.67 GHz Intel Core i5 M 560 with NVidia NVS 3100M GPU and maxed at 8GB RAM coupled with SSDs.  Did test with Ubuntu 20.04 LTS and while they ran great, NVidia just does not provide the support and Nouveau hindered the system so I reverted back to Windows.  I do feel you are right as I suspect the power down issue might have something to do with the Intel M560 CPU. After fresh load, both power up from start to logon in 31 secs.  Power down is not as fast but still at least now it shuts off unlike before.  Both are fully patched.
Issue: Dell Latitude E6410 laptops will not power off the hardware upon Win10 shut down. Specifics: After choosing to shut down in Windows 10, the OS seems to fully close out, but the system power remains on.  Since there is not an active OS, there is no active power management, and so the laptop shifts to a high-power state.  The only way to shut the system down (or get the system to do anything) is to force a power off through holding the power button down for app. 6 seconds.  After this, the computer can be turned on and will restart normally.  Windows can even "restart" the computer without issue, since it is not trying to fully power off the hardware. Context: This issue has now appeared on all the multiple E6410s that I administer, regardless of when the OS has been refreshed (brand new Win10 installs, or up to two years previously that have had recent Windows Updates).  Clearly, this is not a one-system issue; clean Win10 installs using their media creation tool have the problem.  Former two-year old Windows installation that had been working just fine developed this symptom immediately following recent Windows Updates. Attempted Fixes: I have already tried all these things: Apparent Cause: It seems that Microsoft, in their attempt to mitigate the Spectre/Meltdown vulnerabilities, has created this issue because the Dell BIOS is not fully ready for the changes.  However, while Dell has been busy releasing BIOS updates for other systems, the E6410 is not on their list for planned fixes... which leaves us in the lurch.  I believe that a newer BIOS update could address this issue; or, alternatively, a better fix from Microsoft. So... if any one has further ideas of how to address this issue, I would be most grateful. -Enten
E6410 not power down hardware after Win10 updates