Hello Clayton,  Not sure if you have gone through the attached document it could be helpful.  Best practice would be to use different set of eth ports from different SPs  Assuming that you have extra IO Module the configuration would be to use ex - eth2 and eth3 for NFS on SPA  and eth 10 and eth11 for iSCI on SPB , or any combination of eth ports and SPs as per your configuration.  Chris
I'm working with a VNXe 3100 that is utilizing both block iSCSI and NFS for attached VMware ESXi hosts. Up until now, they have only used NFS, but we need to use iSCSI additionally. I have read all kinds of EMC documentation & internet blogs on the subject of multipathing & best practices, but none of them seem to address a configuration where BOTH NFS & iSCSI are in use simultaneously.   For example, in the EMC VNXe High Availability white paper, it talks about configuring iSCSI & then configuring NFS. In both scenarios, they seem to be using the same physical SP ports for both block & file traffic. In my opinion, this wouldn't be best practice since its usually best to isolate iSCSI traffic.In our environment, we have redundant switches between the SP's & ESXi hosts. My thought is that there should be a seperate VLAN & physical interface for iSCSI and seperate VLAN and interfaces for NFS. We are only using 1Gb ports. Thoughts?  I'd love to either see documentation or someone's firsthand experience on how this is accomplished according to best practices. Let me know if you need more details. Thanks in advance.
VNXe NFS & iSCSI Interface Configuration