Nah, the tab would act as a secure lock on one side of the graphics card.  If you make sure the bracket on other side of the graphics card will be secured to the chassis, it will stay in place and works properly. Some heavy cards require extra support brackets on top of the cards and connecting to the chassis but those were required on XPS, Precision, etc.  As OptiPlex was not designed to handle large, heavy graphics card.  Users must modify some type of support for the cards if used, the blue tab alone would not handle the stress on the PCIe x16 slot when the machine is on vertical position. You can also operating the machine on its side (motherboard side).
When taking my gpu I pressed it to hard and it flew away. I reinstalled the card to see if everything was working and everything was working. I then took the gpu out without the tab. I’ll be installing a new card next week. Will this affect the pc in anyway?  [IMAGE]
I accidentally broke the pice blue tab off, should I be worried?