Yes, as long as you've kept home server up to date.
I have a two year old Dell T110 Server with Intel Xeon X3430 processor running Windows Home Server software.  It has been running great since February 2010.  My computers are Windows XP and are 9, 8 and 8 years old.  I need to get new ones.  The new ones I have access to have Windows 7 Professional 64 bit operating systems.  Will these computers communicate (Backup and Storage) with the T110 running the Windows Home Server software? (I understand that the version of Windows Home Server was built from Windows Server 2003.)  Thank you!
Windows Home Server 2011 64 Bit - Work on a Dell T110?