Hello,  Yes the guide is updated regularly, typically monthly or as updates are available.   Since the 4500-x isn't a Nexus series switch, you're not looking for DCB support correct?   In cases like these Dell offers "Level 3" best resonable effort support.   I would make sure you use latest IOS and EQL firmware.  There are other IOS catalyst switches in the guide.  Configuring it along those lines would be a great place to start.   Ideally, the switch would be dedicated for iSCSI use, not VLANd with other traffic.    If you can first test this before production, then support can review array diagnositcs and SANHQ archives for any signs of network related issues.   (retrans rates, and types for example)   Regards, 
I would like to know if Dell storage compatibility matrix is updated regularly, specifically for cisco switches.We are looking to deploy some PS6210 with 10G connectiivity and would like to use with Cisco 4500X series switches. However these are not listed in the doc. There are a few cisco switches that are end of life (4948 and some nexus switches).
Cisco 10G switch