After reviewing the system further it turned out I had a faulty SFP in the new FC switch. It was in use the day prior. Not sure what happened in that time, but replacing it solved the problem.
I'm in the process of upgrading to a more performant FC switch. When I disconnect the FC cable from the SFP on the old FC switch and connect it to a new SFP on a new FC switch, the Unity 300 is not recognizing the new connection. Do/Can/Must I purge the old initiators to allow for the new connection? The port configuration on the FC switch is the same as the old switch.
Migrating Unity 300 FC connections to new FC switch