[NAME] Version of Windows? Are all your drivers up-to-date? What Bluetooth error are you seeing? Is BT listed in Device Manager? In Device Manager, click View>Show hidden on the toolbar. Now look everywhere in Device Manager for any Unknown devices. Right-click and uninstall all "Unknown" devices. Then click Action>Scan for hardware changes on toolbar and see if BT appears and works again. What USB devices are being disconnected? Does PC lose those USB connections after it goes to sleep and you can't wake it up, or randomly while you're actively using the PC?  
my aio 5400 has bluetooth error and often loses usb connection, keyboard and mouse, please help me how to fix it
my aio 5400 has bluetooth error and often loses usb connection, keyboard and 
mouse.