Hello,   The array isn't impacted by volume size.  It's all just blocks of data.  At the SCSI level, a LUN has a negotiated queue value.  From 0 - 255.  Typical values are 64-128.  When that limit is hit, I/O to that LUN is paused until IO is processed by the storage, and the queue drained.   So if you had one 64TB LUN that would mean one queue per LUN.  That can be an limit on performance. Additionally,  how OS's cache LUNs comes into play as well.  More volumes can produce higher cache hit rates.    Again a lot goes to what the application is.  For example with SQL, I always give them their own volumes. I never run multiple instances of SQL on the same volume.   Another benefit is it's easier to monitor performance if you have more volumes.   Don 
We are going to provision a storage from Dell compellent SC 4020 for 48TB to a new environment, we end up in a confusion to decide with the size of LUN. Please suggest.   Option1 : 24 * 2 TB =48 TB   Option 2: 8 * 6 TB =48TB  Model : SC 4020 Host details : Microsoft Hyper –v 2012 ( it can support up to 64 TB LUNs)  ThanksSaran  
Dell Compellent LUN Size for Hyper -v 2012 host