Most new systems -- this one qualifies -- do not support M.2 SATA drives -- only NVMe.  
Hi, I'm running out of storage space on my Dell Inspiron 15 5501 originally shipped with NVMe WDC 256GB. Bought WD blue 3d nand sata ssd m.2 2280 500GB. Unfortunately after installing it into the empty SSD2 slot and powered on the laptop error message appear right after the Dell Logo. "Hard Drive - Not Installed". I checked the BIOS there is no ssd detected in both slots. But when I uninstall the new ssd and then start my laptop again it load Windows 10 like usual, when I checked the BIOS it shows in the Drive Information M.2 PCIe SSD-0 = 256GB PC SN530NVMe WDC 256GB, Tried a couple of time but still facing the same problem. I could not find any write up / video on forums or dell support.  Your help will be greatly appreciated.  
Error message "hard drive - not installed" appear after installing wd blue 3d 
nand sata ssd m.2 2280 into the empty SSD2 slot