No, this goes against the design of the appliance.  Let VxRail self optimize for all workloads and use QoS to fence off just the few low priority or potentially noisy ones.  Btw, SSD is used for write cache in hybrid appliances - so data on HDD gets the benefit.  C
Is it possible to isolate workloads on a select set of resources in the appliance? If so, are there any risks associated with designing the appliance in the manner? For example, if a customer needs to dedicate a VM to EFD drives while allowing the remaining disks to be shared with all other VMs.
Isolating Workoads