Can you try deleting any (or all) self issued certificates from IE?
One of my customers cannot login to the Unisphere mgt interface on their VNXe from their desktops.  When browsing to the mgt-IP they get a "Confirm Certificate" popup, and whatever they choose the next screen is a empty page with "Internet Explorer cannot open the webpage", and no Unisphere login page is displayed.This confirm-certificate popup does not seem display a VNXe certificate, but somehow a local certificate. See screenshot.    Adding the IP to the trusted-sites does not help. Also selecting the IE advanced option "dont prompt for client certificate when one one certificate exists" does not help. Only the popup message disappears after that, but still no Unisphere login is displayed. Of course all proxy-servers are disabled, and the VNXe is on the same physical subnet as the desktops.   When connecting a WindowsXP client to the same network they get a Unisphere login page and can login normally.  Any ideas?
Windows7/IE9 login problem on VNXe