User: When did the Great plague of London start and when did it end?
Assistant: The Great Plague of London started in 1665 and ended in 1666. It is also known as the Great Plague of London, or the Black Death, because of the dark blotches on the skin of those who died from it. It is estimated that around 100,000 people died in London during the plague, which was one of the deadliest pandemics in history.