the following description and examples illustrate a preferred embodiment of the present invention in detail . those of skill in the art will recognize that there are numerous variations and modifications of this invention that are encompassed by its scope . accordingly , the description of a preferred embodiment should not be deemed to limit the scope of the present invention . according to the present invention , information relating to the rate of a chemical reaction that yields at least one electroactive product can be obtained using an electrochemical cell by ensuring that the chemical reaction is localized at a site remote from the electrode used to electrochemically react the electroactive product ( s ). methods and devices for obtaining electrochemical measurements of fluid samples are discussed further in copending u . s . patent application ser . no . 09 / 616 , 433 , filed on jul . 14 , 2000 , entitled “ immunosensor ,” copending u . s . patent application ser . no . 09 / 616 , 512 , filed on jul . 14 , 2000 , entitled “ hemoglobin sensor ,” and copending u . s . patent application ser . no . 09 / 615 , 691 , filed on jul . 14 , 2000 , entitled “ antioxidant sensor ,” each of which is incorporated herein by reference in its entirety . the site of the chemical reaction needs to be sufficiently removed from the electrode such that the mass transfer of the electroactive species from the chemical reaction site to the electrode effectively controls the current flowing at the electrode at any time . this arrangement ensures a substantially linear electroactive species concentration gradient between the chemical reaction site and the electrode . the concentration of the electroactive species is maintained at effectively zero at the electrode by the electrochemical reaction taking place there . the time course of the magnitude of this concentration gradient will therefore be substantially determined only by the time course of the concentration of the electroactive specie ( s ) at the chemical reaction site and the diffusion coefficient ( s ) of the electroactive reaction product ( s ) in the liquid medium . since the current flowing at the electrode is proportional to the concentration gradient of the electroactive specie ( s ) at the electrode , the time course of this current will reflect the time course of the chemical reaction occurring at the remote site . this allows the current measured at the electrode ( or charge passed if the current is integrated ) to be a used as a convenient measure of the rate and extent of the chemical reaction taking place . an example of a suitable method for ensuring that the chemical reaction is remote from the working electrode is to immobilize one or more of the reaction components on a solid surface remote from the electrode . the reaction component ( s ) can be immobilized by incorporating them in a polymeric matrix that is dried on or otherwise attached to the solid surface . the reaction component ( s ) can also be tethered directly to the solid surface either by chemical or physical bonding . alternatively one or more of the reaction components can simply be dried onto the solid surface without special immobilization means . in this situation one or more of the reaction components needs to be sufficiently low in mobility , in the liquid matrix filling the electrochemical cell , that it does not migrate substantially from the position where it was dried during the time period that the electrochemical current can be usefully monitored to perform the required measurement . in this context substantial migration means that the slowest moving component required for the chemical reaction approaches closely enough to the working electrode that cottrell type depletion kinetics begin to effect the time course of the current flowing at the electrode . the range of separation distance between the chemical reaction site and the working electrode in the present invention is desirably less than about 1 cm , preferably less than 5 mm , more preferably between 5 , 10 , 50 , 100 , 200 , 500 microns and 5 mm , more preferably between 5 , 10 , 50 , 100 , 200 and 500 microns , and most preferably between 5 , 10 , 50 , 100 and 200 microns . as well as the working electrode , at least a counter electrode in contact with the liquid sample needs to be provided to complete the electrochemical circuit . optionally the counter electrode can function as a combined counter / reference electrode or a separate reference electrode can be provided . in a preferred embodiment , the working electrode and counter electrode are desirably spaced apart at a distance greater than about 300 microns , preferably at a distance greater than about 500 microns , more preferably at a distance between about 500 microns and 10 mm , more preferably at a distance between about 500 microns and 1 , 2 , 5 mm , and most preferably between 1 mm and 2 , 5 , 10 mm . the working electrode needs to be constructed of materials that do not react chemically with any component with which it will come into contact during use to an extent that interferes with the current response of the electrode . if the working electrode is to be used as an anode then examples of suitable materials are platinum , palladium , carbon , carbon in combination with inert binders , iridium , indium oxide , tin oxide , mixtures of indium and tin oxide . if the working electrode is to be used as a cathode then in addition to the material listed above other suitable materials are steel , stainless steel , copper , nickel , silver and chromium . examples of materials suitable for the counter electrode are platinum , palladium , carbon , carbon in combination with inert binders , iridium , indium oxide , tin oxide , mixture of indium and tin oxide , steel , stainless steel , copper , nickel , chromium , silver and silver coated with a substantially insoluble silver salt such as silver chloride , silver bromide , silver iodide , silver ferrocyanide , silver ferricyanide . the site of the chemical reaction can be localized on a bare wall or on the counter electrode , remote from the working electrode . the site of the chemical reaction can be on the same plane as the working electrode or more preferably in a plane facing and substantially parallel to the working electrode . fig1 depicts an apparatus suitable for use with one embodiment of the current invention . in fig1 , a working electrode 2 and a counter electrode 3 are disposed on an electrically insulating substrate 1 . on a second substrate 5 is disposed a layer of chemical reactants 4 , where at least one of the reactants is substantially immobilized on the substrate 5 . in use , the space between walls 1 and 5 is filled with a liquid containing a substance which is capable of reacting with the reagents 4 to produce at least one electroactive species . the products of the chemical reaction diffuse towards the working electrode 2 where the electroactive specie ( s ) are electrochemically reacted to produce a current . the magnitude of the current or the charge passed at a particular time , or the time course of the current or charge passed can then be used to obtain a measure of the rate or extent of the chemical reaction occurring at the reactant layer 4 . fig2 depicts another embodiment of the current invention . the numbering of the components in fig2 correspond to the components in fig1 . in fig2 the reactants 4 are disposed on the counter electrode 3 which is disposed on an electrically resistive substrate 5 . in this embodiment the materials of construction of the counter electrode 3 must be inert to reaction with any of the components of the reactants 4 disposed on the electrode 3 . an example of a chemistry and reaction that is suitable for use with the current invention is measuring glucose in whole blood using the enzyme pqq dependent glucose dehydrogenase ( gdhpqq ) and a redox mediator . in this reaction glucose in the blood reacts with gdhpqq to form gluconic acid . in the process , the pqq in the enzyme is reduced . a mediator , such as potassium ferricyanide , then oxidizes the pqq in the enzyme and forms ferrocyanide . the enzyme in the oxidized form can then react with further glucose . the net effect of this reaction is to produce two ferrocyanide molecules for each glucose molecule reacted . ferrocyanide is an electroactive species , and so can be oxidized at an electrode to produce a current . other suitable enzymes for this reaction are glucose oxidase ( god ) or nad dependent glucose dehydrogenase . for other reactions , lactate dehydrogenase and alcohol dehydrogenase may be used . other suitable redox mediators include ferrocinium , osmium complexes with bipyridine , and benzophenone . the reaction of glucose in whole blood with the enzyme can be slow , taking up to a few minutes to go to completion . also , the higher the haematocrit of the blood sample , the slower the reaction . the haematocrit of the blood is the volume fraction of red cells in the whole blood sample . in this example , an electrochemical cell according to fig2 was constructed . a solution containing 50 mg / ml gdhpqq , 0 . 9 m potassium ferricyanide and 50 mm buffer at ph 6 . 5 was deposited on the counter electrode and the water removed to leave a dried reactant layer . in this layer the gdhpqq is large enough to be effectively immobilized on the counter electrode , whereas the ferricyanide can mix more evenly throughout the liquid in the electrochemical cell . the blood sample was introduced into the cell and a potential of + 300 mv immediately applied between the working electrode and the counter electrode . although a potential of + 300 mv is most preferred for oxidizing ferrocyanide , the potential is desirably between + 40 mv and + 600 mv , preferably between + 50 mv and + 500 mv , and more preferably between + 200 mv and + 400 mv . in the cell , the working electrode consisted of a layer of gold sputtered onto a polyester substrate and the counter electrode consisted of a layer of palladium sputtered onto a polyester substrate . the current traces recorded for blood samples of different haematocrits , showing a faster rate of reaction in lower haematocrit blood , are given in fig3 . the number at the end of each line is the percent haematocrit of the blood sample used , i . e ., 20 %, 42 %, and 65 %, respectively . the glucose level in each blood sample is approximately the same , namely 5 . 4 mm for the 65 % haematocrit sample , 5 . 5 mm for the 42 % haematocrit sample , and 6 . 0 mm for the 20 % haematocrit sample . the current shown in fig3 can be approximately given by the equation : where i is the current , f is faraday &# 39 ; s constant ( 96486 . 7 c / mole ), a is the electrode area , d is the diffusion coefficient of the ferrocyanide in the sample , c is the concentration of ferrocyanide at the reaction site and l is the distance between the reaction site and the electrode . the reaction rate , given by the rate of change of c with time is therefore given by : for the reactions depicted in fig3 , between 6 and 8 seconds for the 20 %, 42 % and 65 % haematocrit samples , the average di / dt was 3 . 82 , 2 . 14 and 1 . 32 microamps / second , respectively . the diffusion coefficients of ferrocyanide for these samples were 2 . 0 × 10 − 6 , 1 . 7 × 10 − 6 and 1 . 4 × 10 − 6 cm 2 / sec for 20 %, 42 %, and 65 % haematocrit samples , respectively . the electrode area was 0 . 1238 cm 2 and l was 125 microns . these values yield reaction rates of 2 . 0 , 1 . 3 , and 0 . 99 mm / second for the 20 %, 42 % and 65 % haematocrit samples , respectively . the above description discloses several methods and materials of the present invention . this invention is susceptible to modifications in the methods and materials , as well as alterations in the fabrication methods and equipment . such modifications will become apparent to those skilled in the art from a consideration of this disclosure or practice of the invention disclosed herein . consequently , it is not intended that this invention be limited to the specific embodiments disclosed herein , but that it cover all modifications and alternatives coming within the true scope and spirit of the invention as embodied in the attached claims .