OncoLoop: A network-based precision cancer medicine framework
HIF-dependent expression of creatine kinase brain isoform (CKB) promotes breast cancer metastasis, whereas cyclocreatine therapy impairs invasion and improves the efficacy of conventional chemotherapies
Robust retrieval of data stored in DNA by de Bruijn graph-based de novo strand assembly Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Many dissimilar protein domains switch between α-helix and β-sheet folds Transcription activation is enhanced by multivalent interactions independent of phase separation Ultrahigh-Throughput Ambient MS: Direct Analysis at 22 Samples per Second by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry An NLR Integrated Domain toolkit to identify plant pathogen effector targets Trypanosomal variant surface glycoprotein expression in human African trypanosomiasis patients A tool for assessing alignment of biomedical data repositories with open, FAIR, citation and trustworthy principles Nanocrown electrodes for reliable and robust intracellular recording of cardiomyocytes and cardiotoxicity screening A new method for the sampling and preservation of placental specimens in low-resource settings for the identification of P. falciparum and analysis of nucleic acids Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes with Chemical Crosslinking Mass Spectrometry The developmental changes in intrinsic and synaptic properties of prefrontal neurons enhance local network activity from the second to the third postnatal week Construction of a new chromosome-scale, long-read reference genome assembly for the Syrian hamster, Mesocricetus auratus Experimental sexual selection reveals rapid evolutionary divergence in sex-specific transcriptomes and their interactions following mating Learning and motor inhibitory control in crows and domestic chickens Estrogen-related receptor alpha and Rplp1-dependent translation coordinately regulate starvation response and decrease NASH progression Liberation from fibrogenesis or tumorigenesis via cellular senescence by a novel small molecule Cell Rearrangement Generates Pattern Emergence as a Function of Temporal Morphogen Exposure. A rationalized definition of tumor suppressor microRNAsexcludes miR-34a Hotspots of pest-induced US urban tree death, 2020-2050 High glucose enhances antigen-independent CTL killing via TRAIL First Report of Lactoria cornuta from Karnataka, West coast of India, Role of tropical cyclones in Range Extension Integrative small and long RNA-omics analysis of human healing and non-healing wounds discovers cooperating microRNAs as therapeutic targets