Discovery of highly potent pancoronavirus fusion inhibitors that also effectively inhibit COVID-19 variants from the UK (Alpha), South Africa (Beta), and India (Delta)
Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: the Multi-Targeting Drug DREAM Challenge
From smooth cortical gradients to discrete modules: spontaneous and topologically robust emergence of modularity in grid cells Modulation of RecFORQ- and RecA-mediated homologous recombination in Escherichia coli by isoforms of translation initiation factor IF2 Microorganisms Characterization in Anaerobic Solventogenic Processing of Volatile Fatty Acids Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition First evidence of in vitro cytotoxic effects of marine microlitter on Merluccius merluccius and Mullus barbatus, two Mediterranean commercial fish species Substrate dynamics contribute to enzymatic specificity in human and bacterial methionine adenosyltransferases Tunable Cellular Localization and Extensive Cytoskeleton-Interplay of Reflectins Supergenes origin and maintenance in Atlantic cod Inter-tissue convergence of gene expression during ageing suggests age-related loss of tissue and cellular identity Pathways of savannization in a mesic African savanna-forest mosaic following an extreme fire A MALDI-TOF assay identifies nilotinib as an inhibitor of inflammation in acute myeloid leukaemia A Hierarchy of Biomolecular Proportional-Integral-Derivative Feedback Controllers for Robust Perfect Adaptation and Dynamic Performance Failure to account for behavioral variability significantly compromises accuracy in indirect population monitoring The 55K SNP-Based Exploration of QTL for Spikelet Number Per Spike in a Tetraploid Wheat (Triticum turgidum L.) Population: Chinese Landrace Ailanmai X Wild Emmer Expression and subcellular localization of USH1C/harmonin in the human retina provides insights into pathophysiology and therapy of Usher syndrome A bacterial effector counteracts host autophagy by promoting degradation of an autophagy component Polycystins are upregulated in fibrotic kidneys and promote renal fibrosis The biochemical resolving power of fluorescence lifetime imaging: untangling the roles of the instrument response function and photon-statistics Oct1 recruits the histone lysine demethylase Utx to promote lineage specification Pan-cancer HLA Gene-mediated Tumor Immunogenicity and Immune Evasion Ensovibep, a novel trispecific DARPin candidate that protects against SARS-CoV-2 variants The renal inflammatory network of nephronophthisis Vocal markers of autism: assessing the generalizability of machine learning models "Adopt a Microorganism" methodology enhances the discourse richness of high school students in both hybrid learning and remote education