SARS-CoV-2 variants show a gradual declining pathogenicity and pro-inflammatory cytokine spur, an increasing antigenic and anti-inflammatory cytokine induction, and rising structural protein instability
Estimating cell-type-specific gene co-expression networks from bulk gene expression data with an application to Alzheimer's disease
Increased susceptibility to Chrysanthemum Yellows phytoplasma infection in Atcals7 ko plants is accompanied by enhanced expression of carbohydrate transporters. Design, Mutate, Screen: High-throughput creation of genetic clocks with different period-amplitude characteristics Single-cell Transcriptomic Profiling Unveils Cardiac Cell-type Specific Response to Maternal Hyperglycemia Underlying the Risk of Congenital Heart Defects Egress of human cytomegalovirus through multivesicular bodies Potent but transient immunosuppression of T-cells is a general feature of CD71+ erythroid cells Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury Quercetin handles cellular oxidant / antioxidant systems and mitigates immunosenescence hallmarks in human PBMCs: an in vitro study Repeated introduction of micropollutants enhances microbial succession despite stable degradation patterns Frequency modulated timer regulates mammalian hibernation MG53 slows neuromuscular junction loss and prolongs survival in ALS Genetic analysis of praziquantel response in schistosome parasites implicates a Transient Receptor Potential channel Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Conformational decoupling in acid-sensing ion channels uncovers mechanism and stoichiometry of PcTx1-mediated inhibition The coiled coil of FtsLB is a structurally detuned element critical for modulating activation in bacterial cell division Allopurinol Blocks The Formation And Progression Of Aortic Aneurysm In A Mouse Model Of Marfan Syndrome Naming Human Diseases: Ethical Principles of Curating Exclusive Substitute for Inopportune Nosology From fitting the average to fitting the individual: A cautionary tale for mathematicalmodelers In vitro evolution of uracil glycosylase towards DnaKJ and GroEL binding evolves different misfolded states Human cells contain myriad excised linear intron RNAs with links to gene regulation and potential utility as biomarkers Stimulus manipulations permit activation of fiber subpopulations in the mouse and rat vagus In Vivo Multi-Day Calcium Imaging of CA1 Hippocampus in Freely Moving Rats Reveals a High Preponderance of Place Cells with Consistent Place Fields Diurnal activity budget and conservation implication of Hippopotamus amphibius at Bui National Park, Ghana NUCLEAR RETENTION OF LEPTIN/UPD2 REGULATES ORGANISMAL RESILIENCE TO NUTRIENT EXTREMES Predictive uncertainty in mechanistic models of cellular processes calibrated to experimental data