Comparative infection and pathogenesis of SARS-CoV-2 Omicron and Delta variants in aged and young Syrian hamsters
Identification of druggable host targets needed for SARS-CoV-2 infection by combined pharmacological evaluation and cellular network directed prioritization both in vitro and in vivo.
Glucose regulates expression of pro-inflammatory genes IL-1β and IL-12 through a mechanism involving hexosamine biosynthesis pathway dependent regulation of α-E catenin in the RAW 264.7 macrophage cell line CellKb Immune: a manually curated database of mammalian hematopoietic marker gene sets for rapid cell type identification Developing High-Affinity Decoy Receptor Optimized for Multiple Myeloma and Diffuse Large B Cell Lymphoma Treatment Small extracellular vesicles from young mice prevent frailty, improve healthspan and decrease epigenetic age in old mice. Antennapedia and optix regulate metallic silver wing scale development and cell shape in Bicyclus anynana butterflies Cellular feedback to organotelluranes displays modulation of antioxidant proteins gene expression Using total RNA quality metrics for time since deposition estimates in degrading bloodstains Microbial colonization of tannin-rich tropical plants: interplay between degradability, methane production and tannin disappearance in the rumen Analysis of science journalism reveals gender and regional disparities in coverage Extracellular Matrix Hydrogels Promote Expression of Muscle-Tendon Junction Proteins Probing the effect of glycosaminoglycan depletion on integrin interactions with collagen I fibrils in the native ECM environment. Rho Kinase regulates neutrophil NET formation that is involved in UVB-induced skin inflammation Gene loss during a transition to multicellularity Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Global structural stability and the role of cooperation in mutualistic system The obstacles and potential clues of prime editing applications in tomato, a dicot plant Outbreak.info Research Library: A standardized, searchable platform to discover and explore COVID-19 resources Synergistic balance of local segregation and global integration mechanisms in large-scale brain networks underlies perceptual experience In vitro pectate lyase activity and carbon uptake assays and whole genome sequencing of Bacillus amyloliquefaciens subsp. plantarum strains for a pectin defective pathway Exploitation of the genetic variability in the genotype of Egyptian Wheat by studding Molecular Markers, Molecular Docking and Nano Composites. Regulation of leaf and stem rust Detecting cell-of-origin and cancer-specific methylation features of cell-free DNA from Nanopore sequencing LabGym: quantification of user-defined animal behaviors using learning-based holistic assessment Diverse classes of constraints enable broader applicability of a linear programming-based dynamic metabolic modeling framework The conserved zinc-finger protein GTSF1helps PIWI proteins achieve their full catalytic potential