Navigating the amino acid sequence space between functional proteins using a deep learning framework
Enhancing the prediction of protein coding regions in biological sequence via a deep learningframework with hybrid encoding
Inhibitory proteins block substrate access by occupying the active site cleft of Bacillus subtilis intramembrane metalloprotease SpoIVFB Structure-Functional-Selectivity Relationship Studies on A-86929 Analogs and Small biaryl Fragments toward Discovery of biased D1 agonists The response network of HSP70 defines vulnerabilities in cancer cells with the inhibited proteasome The female pheromone (Z)-4-undecenal mediates flight attraction and courtship in Drosophila melanogaster Second Heart Field-derived Cells Contribute to Angiotensin II-mediated Ascending Aortopathies Multiscale model of primary motor cortex circuits predicts in vivo cell type-specific, behavioral state-dependent dynamics Modulation of P2X4 pore closure by magnesium,potassium, and ATP Reconstitution of minimal motility system based on Spiroplasma swimming by expressing two bacterial actins in synthetic minimal bacterium An End-to-End Deep Learning Speech Coding and Denoising Strategy for Cochlear Implants DNA supercoiling-mediated collective behavior of co-transcribing RNA polymerases GPI-anchored FGF directs cytoneme-mediated bidirectional signaling to self-regulate tissue-specific dispersion LEA motifs promote desiccation tolerance in vivo Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing Environment-dependence of the expression of mutational load and species' range limits Metabarcoding faecal samples to investigate spatiotemporal variation in the diet of the endangered Westland petrel (Procellaria westlandica) Omicron booster in ancestral strain vaccinated mice augments protective immunities against both the Delta and Omicron variants Computational modeling and quantitative cell physiology reveal central parameters for the brassinosteroid-regulated cell growth of the Arabidopsis root Comparison of hybrid learning and remote education in the implementation of the 'Adopt a Microorganism' methodology Expression and subcellular localization of USH1C/harmonin in the human retina provides insights into pathophysiology and therapy of Usher syndrome Chromosomal rearrangements with stable repertoires of genes and transposable elements in an invasive forest-pathogenic fungus Nutrient metabolism regulates insulin granule formation in the pancreatic islet β-cell via ER redox homeostasis Unheeded SARS-CoV-2 proteins? A deep look into negative-sense RNA Feed efficiency of lactating Holstein cows was not as repeatable across diets as within diet over subsequent lactation stages Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition