An ACE2-dependent Sarbecovirus in Russian bats is resistant to SARS-CoV-2 vaccines
Experimental evolution reveals post-transcriptional regulation as a novel driver of Leishmania fitness gain
Superinfection exclusion: a viral strategy with short-term benefits and long-term drawbacks RNA degradation of blood reveals a time diagnostic window in a controlled environment Manduca sexta experience high parasitoid pressures in the field but minor fitness costs of consuming plant secondary compounds Protein contact map prediction using multiple sequence alignment dropout and consistency learning for sequences with fewer homologs Fast ATP-dependent Subunit Rotation in Reconstituted FoF1-ATP Synthase Trapped in Solution A CNN model with feature integration for MI EEG subject classification in BMI Outcome-selective reinstatement is predominantly context-independent, and associated with c-Fos activation in the posterior dorsomedial striatum Natural variants in SARS-CoV-2 S protein pinpoint structural and functional hotspots; implications for prophylaxis and therapeutics strategies Functional buffering via cell-specific gene expression promotes tissue homeostasis and cancer robustness First detection of herpesvirus and prevalence of mycoplasma infection in free-ranging Hermann s tortoises (Testudo hermanni), and in potential pet vectors A rat model of pregnancy in the male parabiont Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Epidural Electrical Stimulation of the Cervical Dorsal Roots Restores Voluntary Upper Limb Control In Paralyzed Monkeys A bacterial extracellular vesicle-based intranasal vaccine against SARS-CoV-2 protects against disease and elicits neutralizing antibodies to wild-type virus and Delta variant A family of unusual immunoglobulin superfamily genes in an invertebrate histocompatibility complex Rec8 cohesin-mediated axis-loop chromatin architecture is required for meiotic recombination Small extracellular vesicles from young mice prevent frailty, improve healthspan and decrease epigenetic age in old mice. Spontaneous differentiation leads to emergence of hybrid cell states relate to poor prognosis in oral cancer A network approach to genetic circuit designs Balancing sensitivity and specificity in preclinical research Glucose inhibits haemostasis and accelerates diet-induced hyperlipidaemia in zebrafish larvae Tackling polypharmacology of kinase inhibitors and selecting chemical kinase probes by transcription factor activity profiling. Differed cell division angle, position of cell proliferative area, and localization of ANGUSTIFOLIA3 in lateral organs High-Potency Polypeptide-based Inhibition of Enveloped-virus Glycoproteins