Directed evolution of angiotensin-converting enzyme 2 (ACE2) peptidase activity profiles for therapeutic applications
Discovery of Aminoglycosides as First in Class, Nanomolar Inhibitors of Heptosyltransferase I
Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication Synthetic periphyton as a model system to understand species dynamics in complex microbial freshwater communities Evolution of class-structured populations in fluctuating environments LADON, a natural antisense transcript of NODAL, promotes an invasive behaviour in melanoma cells. E156G and Arg158, Phe-157/del mutation in NTD of spike protein in B.1.617.2 lineage of SARS-CoV-2 leads to immune evasion through antibody escape Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Polycystins are upregulated in fibrotic kidneys and promote renal fibrosis Cellular feedback to organotelluranes displays modulation of antioxidant proteins gene expression Non-Newtonian Blood Rheology Impacts Left Atrial Stasis in Patient-Specific Simulations The OPAQUE1/DISCORDIA2 myosin XI is required for phragmoplast guidance during asymmetric cell division in maize Potent but transient immunosuppression of T-cells is a general feature of CD71+ erythroid cells HYBRID REACTION-DIFFUSION AND CLOCK-AND-WAVEFRONT MODEL FOR THE ARREST OF OSCILLATIONS IN THE SOMITOGENESIS SEGMENTATION CLOCK AICAR-mediated selection of karyotypically normal cells in Pallister-Killian syndrome patient-derived skin fibroblasts First evidence of in vitro cytotoxic effects of marine microlitter on Merluccius merluccius and Mullus barbatus, two Mediterranean commercial fish species Naming Human Diseases: Ethical Principles of Curating Exclusive Substitute for Inopportune Nosology Metacommunities from bacteria to birds: stronger environmental effects in mediterranean than in tropical ponds. caliPER: A software for blood-free parametric Patlak mapping using PET/MRI input function. 3D Reconstructions of Mouse Skeletal Muscle Reveal a Decrease in the MICOS Complex and Altered Mitochondrial Networks Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies C. elegans PEZO-1 is a Mechanosensitive Ion Channel Involved in Food Sensation Graph Ricci Curvatures Reveal Atypical Functional Connectivity in Autism Spectrum Disorder Characterisation of protease activity during SARS-CoV-2 infection identifies novel viral cleavage sites and cellular targets with therapeutic potential Natural tolerance to transposition is associated with double-strand break repair and germ-cell differentiation Long term analysis of social structure: evidence of age-based consistent associations in male Alpine ibex