Development of a Novel PROTAC using the Nucleic Acid Aptamer as a Targeting Ligand for Tumor Selective Degradation of Nucleolin
A multiscale lipid and cellular atlas of the human kidney
ConVarT: a search engine for orthologous variants and functional inference of human genetic variants Gene expression and DNA methylation consistently predict cancer mutation states An Erwinia amylovora inducible promoter for improvement of apple fire blight resistance Integrative analysis reveals aged clonal B cells, microenvironment and c-Myc activation in the origin of age-related lymphoma Fine-scale adaptations to environmental variation and growth strategies drive phyllosphere Methylobacterium diversity. Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Manipulating the microbiome alters regenerative outcomes in Xenopus laevis tadpoles via lipopolysaccharide signalling Bulk-assembly of monodisperse coacervates and giant unilamellar vesicles with programmable hierarchical complexity Ear pinnae in a neotropical katydid function as ultrasound guides for bat call detection If Research is Not the Evidence, What is it? The Lack of Research Citations in Health Vlogs Changes in Behavior and Salivary Serum Amyloid A in cows with Subclinical Mastitis Methylation pattern of polymorphically imprinted nc886 is not conserved across mammalia Single cell genomics reveals plastid-lacking Picozoa are close relatives of red algae Network centrality is the most important variable determining gene sequence evolution rates in Schizosaccharomyces pombe Inflammasome activation in infected macrophages drives COVID-19 pathology Disruption of the microphysiological niche alters matrix deposition and causes loss of mitochondrial Ca2+ control in skeletal muscle fibers ISL1 is necessary for auditory neuron development and contributes towards tonotopic organization Propionate ameliorates diabetes-induced neurological dysfunction through regulating the PI3K/Akt/eNOS signaling pathway Probing Patterning in Microbial Consortia with picCASO: a Cellular Automaton for Spatial Organisation Indirect restoration of ecological interactions: reintroduction of a dung-beetle associated primate increases the recruitment of large seeds Genomic regions associate with major axes of variation driven by gas exchange and leaf construction traits in cultivated sunflower (Helianthus annuus L.) Fatal neuroinvasion and SARS-CoV-2 tropism in K18-hACE2 mice is partially independent on hACE2 expression A mixture of innate cryoprotectants is key for freeze tolerance and cryopreservation of a drosophilid fly larva. Once-daily feeding is associated with better health in companion dogs: Results from the Dog Aging Project