Natural variants in SARS-CoV-2 S protein pinpoint structural and functional hotspots; implications for prophylaxis and therapeutics strategies
Structural basis for cell-type specific evolution of viral fitness by SARS-CoV-2
Differences in gait stability and acceleration characteristics between healthy young and older females Barbary ground squirrels do not have a sentinel system but instead synchronise vigilance The BAF A12T mutation associated with premature aging impedes lamin A/C recruitment to sites of nuclear rupture, contributing to nuclear envelope fragility. Dynamical interactions reconfigure the gradient of cortical timescales Intermittent compression increases flow through a gel: a mechanical model perhaps relevant to flow of cerebrospinal fluid Frequency modulated timer regulates mammalian hibernation Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Water levels primarily drive variation in photosynthesis and nutrient use of scrub Red Mangroves in the southeastern Florida Everglades Key features of the genetic architecture and evolution of host-microbe interactions revealed by high-resolution genetic mapping of the mucosa-associated gut microbiome in hybrid mice VeloViz: RNA-velocity informed embeddings for visualizing cellular trajectories Exploring the natural origins of SARS-CoV-2 in the light of recombination Extended Graphical Lasso for Multiple Interaction Networks for High Dimensional Omics Data Selective Ablation of 3' RNA ends and Processive RTs Facilitate Direct cDNA Sequencing of Full-length Host Cell and Viral Transcripts A chemical screen based on an interruption of zebrafish gastrulation identifies the HTR2C inhibitor Pizotifen as a suppressor of EMT-mediated metastasis Evidence for a hydrogen sulfide-sensing E3 ligase in yeast Naming Human Diseases: Ethical Principles of Curating Exclusive Substitute for Inopportune Nosology ATP dependent polymerization dynamics of bacterial actin proteins involved in Spiroplasma swimming The joint evolution of animal movement and competition strategies Macroscopic control of synchronous electrical signaling with chemically-excited gene expression Severe COVID-19 shares a common neutrophil activation signature with other acute inflammatory states Beneficial effects of novel strains of Aureobasidium pullulans produced 1,3-1,6 β-glucans on non-esterified fatty acid levels in diabetic KKAy mice Primary brain cell infection by Toxoplasma gondii reveals the extent and dynamics of parasite differentiation and its impact on neuron biology. Feline tooth resorption findings from a questionnaire survey on 8115 Finnish cats and a case-control study for a more defined population drawn from the survey Testing for phylogenetic signal in single-cell RNA-seq data