Identification of druggable host targets needed for SARS-CoV-2 infection by combined pharmacological evaluation and cellular network directed prioritization both in vitro and in vivo.
Genetic diversity and connectivity of the Ostreid herpesvirus 1 populations in France: a first attempt to phylogeographic inference for a marine mollusc disease
Analysis of alternative mRNA splicing in vemurafenib-resistant melanoma cells Different contribution of the monkey prefrontal and premotor dorsal cortex in decision making during a transitive inference task Genome-scale metabolic modeling reveals SARS-CoV-2-induced metabolic changes and antiviral targets Investigation of ongoing recombination through genealogical reconstruction for SARS-CoV-2 The Tabula Sapiens: a multiple organ single cell transcriptomic atlas of humans Proton-driven alternating access in a spinster transporter, an emerging family of broad-specificity efflux pumps "Adopt a Microorganism" methodology enhances the discourse richness of high school students in both hybrid learning and remote education Mapping the planet's critical natural assets Loss of functional heterogeneity along the CA3 transverse axis in aging Distinct SARS-CoV-2 antibody reactivity patterns elicited by natural infection and mRNA Vaccination FGF8-mediated signaling regulates tooth developmental pace during odontogenesis Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Model design for non-parametric phylodynamic inference and applications to pathogen surveillance Production and characterization of virus-free, CRISPR-CAR T cells capable of inducing solid tumor regression Common Dynamic Determinants Govern Quorum Quenching Activity in N-terminal Serine Hydrolases A chromosome-level assembly of the "Cascade" hop (Humulus lupulus) genome uncovers signatures of molecular evolution and improves time of divergence estimates for the Cannabaceae family Frequency modulated timer regulates mammalian hibernation Co-infection of Candidatus Piscichlamydia trichopodus (order Chlamydiales) and Henneguya sp (Myxosporea, Myxobolidae) in snakeskin gourami Trichopodus pectoralis (Regan 1910) Differential regulation of degradation and immune pathways underlies adaptation of the ectosymbiotic nematode Laxus oneistus to oxic-anoxic interfaces RapidoPGS: A rapid polygenic score calculator for summary GWAS data without a test dataset HOW CONCERNING IS A SARS-COV-2 VARIANT OF CONCERN? COMPUTATIONAL PREDICTIONS AND THE VARIANTS LABELING SYSTEM The compound of baicalein, wogonin, and oroxylin-A inhibiting EMT in A549 cell line via PI3K/AKT-TWIST1-glycolysis pathway A Hierarchy of Biomolecular Proportional-Integral-Derivative Feedback Controllers for Robust Perfect Adaptation and Dynamic Performance A cell type-specific multiomics uncovers a guard cell-specific RAF15-SnRK2.6/OST1 kinase cascade