Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits
Time- and cell-dependent atypia and cell death are caused by progressive deficiency in DNA replication
Systematic monitoring of photosynthetically-derived oxidative signals by a peroxiredoxin-based biosensor GCN5L1 promotes diastolic dysfunction by inhibiting cardiac pyruvate oxidation Mutualism-enhancing mutations dominate early adaptation in a microbial community NOMA: a high-throughput microchip for robust, sequential measurements of secretions from the same single-cells ALLOPURINOL BLOCKS THE AORTIC ANEURYSM IN A MOUSE MODEL OF MARFAN SYNDROME VIA REDUCING AORTIC OXIDATIVE STRESS Detection and functional resolution of soluble multimeric immune complexes by a comprehensive FcγR reporter cell panel Uncovering Differences in Hydration Free Energies and Structures for Model Compound Mimics of Charged Sidechains of Amino Acids On-pathway multivalency of a broadly neutralizing evolution drug candidate High school science fair: Experiences of two groups of undergraduate bioscience students Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation Comparative toxicogenomics of glyphosate and Roundup herbicides by mammalian stem cell-based genotoxicity assays and molecular profiling in Sprague-Dawley rats Widespread ripples synchronize human cortical activity during sleep, waking, and memory recall Frequency modulated timer regulates mammalian hibernation Synthetic periphyton as a model system to understand species dynamics in complex microbial freshwater communities Precise, Fast and Comprehensive Analysis of Intact Glycopeptides and Modified Saccharide Units with pGlyco3 Population structure analysis and laboratory monitoring of Shigella with a standardised core-genome multilocus sequence typing scheme A novel 5 prime DNA binding site in RFC facilitates PCNA loading for gap DNA repair Usutu virus escapes langerin-induced restriction to productively infect human Langerhans cells, unlike West Nile virus. Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Scaling effects of temperature on parasitism from individuals to host-parasite systems Plasma membrane damage limits replicative lifespan in yeast and induces premature senescence in human fibroblasts An early signaling GARP transcription factor regulates the entry point for differentiation in Giardia HOW CONCERNING IS A SARS-COV-2 VARIANT OF CONCERN? COMPUTATIONAL PREDICTIONS AND THE VARIANTS LABELING SYSTEM Propelling and perturbing appendages together facilitate strenuous ground self-righting