Structural basis of anti-SARS-CoV-2 activity of HCQ: specific binding to N protein to disrupt its interaction with nucleic acids and LLPS
Cryo-EM structure of the Rhodobaca bogoriensis RC-LH1-PufX dimeric complex at 2.9 A
Development and Characterization of PAR-Trackers: New Tools for Detecting Poly(ADP-ribose) In Vitro and In Vivo First Report of Lactoria cornuta from Karnataka, West coast of India, Role of tropical cyclones in Range Extension Surface-associated antigen induces B-cell permeabilization and lysosome exocytosis facilitating antigen uptake and presentation to T-cells Plant biomechanics and resilience to environmental changes are controlled by specific lignin chemistries in each vascular cell type and morphotype Daily torpor reduces the energetic consequences of habitat selection for a widespread bat Host Variation in Type I Interferon Signaling Genes (MX1), CCR5{triangleup}32, and MHC Class I Alleles in Treated HIV+ Non-Controllers Predict Viral Reservoir Size Cell-to-cell variations in subcellular localisation of V2R are independent of its expression level High performance single-cell gene regulatory network inference atscale: The Inferelator 3.0 Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Structural and Functional Analyses Explain Pea KAI2 Receptor Diversity and Reveal Stereoselective Catalysis During Signal Perception Medium-throughput zebrafish optogenetic platform identifies deficits in subsequent neural activity following brief early exposure to cannabidiol and Δ-9-tetrahydrocannabinol Proteomic phenotyping of stimulated Müller cells uncovers profound pro-inflammatory signaling and antigen-presenting capacity AI for predicting chemical-effect associations at the chemical universe level - deepFPlearn NECAB2 participates in an endosomal pathway of mitochondrial stress response at striatal synapses Darting across space and time: Parametric modulators of sex-biased conditioned fear responding C. elegans PEZO-1 is a Mechanosensitive Ion Channel Involved in Food Sensation Second Heart Field-derived Cells Contribute to Angiotensin II-mediated Ascending Aortopathies Effects of fine-scale population structure on the distribution of heterozygosity in a long-term study of (Antirrhinum majus) Usutu virus escapes langerin-induced restriction to productively infect human Langerhans cells, unlike West Nile virus. Micro topographical instruction of bacterial attachment, biofilm formation and in vivo host response A Bayesian model selection approach to mediation analysis Redefining colorectal cancer classification and clinical stratification through a single-cell atlas Co-option of immune effectors by the hormonal signalling system triggering metamorphosis in Drosophila melanogaster Balancing sensitivity and specificity in preclinical research