A platform of patient-derived microtumors identifies individual treatment responses and therapeutic vulnerabilities in ovarian cancer.
Cytosolic EZH2-IMPDH2 complexes regulate melanoma progression via GTP
Apolipoprotein M attenuates anthracycline cardiotoxicity and lysosomal injury Population differences in the length and early-life dynamics of telomeres among European pied flycatchers Land use change through the lens of macroecology: insights from Azorean arthropods and the Maximum Entropy Theory of Ecology Design, Mutate, Screen: High-throughput creation of genetic clocks with different period-amplitude characteristics Rossmann-toolbox: a deep learning-based protocol for the prediction and design of cofactor specificity in Rossmann-fold proteins Annotation of snoRNA abundance across human tissues reveals complex snoRNA-host gene relationships The Skeletal Muscle Circadian Clock Regulates Titin Splicing Through RBM20 T Cell Receptor Beta Germline Variability is Revealed by Inference From Repertoire Data Tracheal tube fusion in Drosophila involves release of extracellular vesicles from multivesicular bodies Reduction of protein disulfide isomerase results in open conformations and stimulates dynamic exchange between structural ensembles Standardised method for cardiomyocyte isolation and purification from individual murine neonatal, infant, and adult hearts Kidney failure alters parathyroid Pin1 phosphorylation and parathyroid hormone mRNA binding proteins leading to secondary hyperparathyroidism Shorter effective lifespan in laboratory populations of D. melanogaster can reduce sexual selection. PIN-FORMED1 polarity in the shoot is insensitive to the polarity of neighbouring cells Comparison of hybrid learning and remote education in the implementation of the 'Adopt a Microorganism' methodology Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Frog nest foams exhibit pharmaceutical foam-like properties Effects of Ancestry and Hypopigmentation Alleles on Skin Color in a Caribbean Native American Population Raman Signal Denoising using Fully Convolutional Encoder Decoder Network Perceiving and remembering speech depend on multifractal nonlinearity in movements producing and exploring speech Failure to account for behavioral variability significantly compromises accuracy in indirect population monitoring Substrate specialization in microbes is driven by biochemical constraints of dynamic flux sensing Rho Kinase regulates neutrophil NET formation that is involved in UVB-induced skin inflammation Salmonella Typhimurium outer membrane protein A (OmpA) renders protection against nitrosative stress by promoting SCV stability in murine macrophages