Development of a Novel PROTAC using the Nucleic Acid Aptamer as a Targeting Ligand for Tumor Selective Degradation of Nucleolin
ATP-binding cassette protein ABCF1 couples gene transcription with maintenance of genome integrity in embryonic stem cells
Live Analysis of Position Effect Variegation (PEV) in Drosophila Reveals Different Modes of Action for HP1a and Su(var)3-9 Diverse classes of constraints enable broader applicability of a linear programming-based dynamic metabolic modeling framework Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Identification of a stereotypic molecular arrangement of endogenous glycine receptors at spinal cord synapses The Inflammatory Role of Milk Fat Globule Epidermal Growth Factor VIII in Angiotensin II Induced Arterial Remodeling Low photorespiratory capacity is sufficient to block the induction of photosynthetic capacity in high light Drug screening at single-organoid resolution via bioprinting and interferometry Infection and transmission of ancestral SARS-CoV-2 and its alpha variant in pregnant white-tailed deer "Adopt a Microorganism" methodology enhances the discourse richness of high school students in both hybrid learning and remote education Embryonic exposure to cannabidiol disrupts active neural circuits, an effect increased by Δ9-tetrahydrocannabinol and involving CB1R and CB2R in zebrafish Mouse CHD4-NURD is required for spermatogonia survival and normal meiotic progression Foraging with friends, moving with anyone: effects of the social environment on movement-integrated habitat selection Trade-offs in biosensor optimization for dynamic pathway engineering C. elegans PEZO-1 is a Mechanosensitive Ion Channel Involved in Food Sensation Translation of upstream open reading frames does not trigger nonsense-mediated decay in Arabidopsis Effects of phenotypic variation on consumer coexistence and prey community structure First evidence of in vitro cytotoxic effects of marine microlitter on Merluccius merluccius and Mullus barbatus, two Mediterranean commercial fish species The Tabula Sapiens: a multiple organ single cell transcriptomic atlas of humans Mutualism-enhancing mutations dominate early adaptation in a microbial community In vivo profiling of site-specific human cancer cell states in zebrafish Systems analysis shows a role of cytophilic antibodies in shaping innate tolerance to malaria T606-phosphorylation deprives the function of Kaiso as a transcription factor and cancer repressor Structural effects driven by rare point mutations in amylin hormone, the type II diabetes-associated peptide ATP binding facilitates target search of SWR1 chromatin remodeler by promoting one-dimensional diffusion on DNA