Generalizing predictions to unseen sequencing profiles via deep generative models
Profiles of expressed mutations in single cells reveal subclonal expansion patterns and therapeutic impact of intratumor heterogeneity
Robustness in regulatory networks of Epithelial Mesenchymal Plasticity as a function of positive and negative feedback loops No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing First detection of herpesvirus and prevalence of mycoplasma infection in free-ranging Hermann s tortoises (Testudo hermanni), and in potential pet vectors Contribution of arm movements to balance recovery after tripping in older adults. Climate warming changes synchrony of plants and pollinators Unsupervised clustering analysis of SARS-Cov-2population structure reveals six major subtypes atearly stage across the world Spatio-temporal, optogenetic control of gene expression in organoids Population bottleneck has only marginal effect on fitness evolution and its repeatability in dioecious C. elegans Nutrient metabolism regulates insulin granule formation in the pancreatic islet β-cell via ER redox homeostasis The RAG1 Ubiquitin Ligase Domain Enhances Assembly and Selection of T Cell Receptor Genes to Restrain the Autoimmune Hazard of Generating T Cell Receptor Diversity Medium-throughput zebrafish optogenetic platform identifies deficits in subsequent neural activity following brief early exposure to cannabidiol and Δ-9-tetrahydrocannabinol Unevolved proteins from modern and prebiotic amino acids manifest distinct structural profiles Modulation of P2X4 pore closure by magnesium,potassium, and ATP Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Stepwise progression of beta-selection during T cell development as revealed by histone deacetylation inhibition Optoception: perception of optogenetic brain stimulation Fatal COVID-19 ARDS associated with incomplete AEC1 differentiation from the transitional state without senescence or fibrosis A platform of patient-derived microtumors identifies individual treatment responses and therapeutic vulnerabilities in ovarian cancer. Citation needed? Wikipedia and the COVID-19 pandemic Structural insights into p300 regulation and acetylation-dependent genome organisation Identification of druggable host targets needed for SARS-CoV-2 infection by combined pharmacological evaluation and cellular network directed prioritization both in vitro and in vivo. Embryo development in Carica papaya Linn. A combined human in silico and CRISPR/Cas9-mediated in vivo zebrafish based approach for supporting gene target validation in early drug discovery Python-Microscope: A new open source Python library for the control of microscopes