AlphaFold2-aware protein-DNA binding site prediction using graph transformer
SARS-CoV-2 variants show a gradual declining pathogenicity and pro-inflammatory cytokine spur, an increasing antigenic and anti-inflammatory cytokine induction, and rising structural protein instability
Limited selection towards lighter seeds in Danish grasslands over an eight-year period Betacoronavirus binding dynamics relevant to the functional evolution of the highly transmissible SARS-CoV-2 variant N501Y An individualized causal framework for learning intercellular communicationnetworks that define microenvironments of individual tumors Mate sharing in male stump-tailed macaques as a possible case of coalition-like behavior to modify the group-wise fitness distribution Sablefish (Anoplopoma fimbria Pallas, 1814) plasma biochemistry and hematology reference intervals including blood cell morphology Cascade screening following a polygenic risk score test: what is the risk of a relative conditional on a high score of a proband? Optogenetic activation of the neural circuit between dorsal raphe nucleus and the pre-Botzinger complex contributes to inhibition of the seizure-induced respiratory arrest in the DBA/1 mouse SUDEP model Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition LPS-TLR4 pathway exaggerates alcohol-induced acute-on-chronic liver failure via provoking NETs formation A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance Evolutionary dynamics of sex-biased genes expressed in cricket brains and gonads A flexible electronic strain sensor for the real-time monitoring of tumor regression Probing Patterning in Microbial Consortia with picCASO: a Cellular Automaton for Spatial Organisation WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2 Abscisic Acid Drives Stomatal Closure through Increases in Hydrogen Peroxide in Distinct Subcellular Compartments Including Mitochondria Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity An Extended Motif in the SARS-CoV-2 Spike Modulates Binding and Release of Host Coatomer in Retrograde Trafficking Tracheal tube fusion in Drosophila involves release of extracellular vesicles from multivesicular bodies Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice Agrobacterium mediated transformation and deciphering SNPs in TaLr67 gene homeologs for gene editing in wheat. Global population genomics of two subspecies of Cryptosporidium hominis during 500 years of evolution "Adopt a Microorganism" methodology enhances the discourse richness of high school students in both hybrid learning and remote education Ultrahigh-Throughput Ambient MS: Direct Analysis at 22 Samples per Second by Infrared Matrix-Assisted Desorption Electrospray Ionization Mass Spectrometry