From GWAS Variant to Function: a Study of ~148,000 Variants for Blood Cell Traits.
Genetic analysis of praziquantel response in schistosome parasites implicates a Transient Receptor Potential channel
Affordable Caenorhabditis elegans tracking system for classroom use Fixed or random? On the reliability of mixed-effects models for a small number of levels in grouping variables Cytosolic EZH2-IMPDH2 complexes regulate melanoma progression via GTP Negative DNA supercoiling makes protein-mediated looping deterministic and ergodic within the bacterial doubling time Value, confidence, deliberation: a functional partition of the medial prefrontal cortex demonstrated across valuation and choice tasks New multiscale characterisation methodology for effective determination of isolationstructure-function relationship of extracellular vesicles. TAS-Seq: a robust and sensitive amplification method for bead-based scRNA-seq Enhancement of CRISPR-mediated homologous recombination-based gene knock-in efficiency by simultaneous HDR overexpression and NHEJ suppression in poplar SARS-CoV-2 variants resist antibody neutralization and broaden host ACE2 usage Accurate prediction of functional states of cis-regulatory modules reveals the common epigenetic rules in humans and mice Placental structure, function and mitochondrial phenotype relate to fetal size and sex in mice First evidence of in vitro cytotoxic effects of marine microlitter on Merluccius merluccius and Mullus barbatus, two Mediterranean commercial fish species Increased early sodium current causes familial atrial fibrillation and dampens effect of flecainide Integrative small and long RNA-omics analysis of human healing and non-healing wounds discovers cooperating microRNAs as therapeutic targets Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Stimulated oxygen transport in tissue by magnetic needle acupuncture Rattus Economicus: A neural model for rational regulation of water-seeking effort in rodents Genomic inference of a human super bottleneck in Mid-Pleistocene transition F1F0 ATP Hydrolysis is a Determinant of Metabolic Rate, a Correlate of Lifespan, and a Weakness of Cancer Quantifying the Morphology and Mechanisms of Cancer Progression in 3D in-vitro environments: Integrating Experiments and Multiscale Models Rho Kinase regulates neutrophil NET formation that is involved in UVB-induced skin inflammation Development of a Novel PROTAC using the Nucleic Acid Aptamer as a Targeting Ligand for Tumor Selective Degradation of Nucleolin Evaluation of SARS-CoV-2 Entry, Inflammation and New Therapeutics in Human Lung Tissue Cells Ribosome actuator via the SpoT/ppGpp pathway to mitigate gene overexpression burden