The combined treatment of Molnupiravir and Favipiravir results in a marked potentiation of efficacy in a SARS-CoV2 hamster infection model through an increased frequency of mutations in the viral genome.
Analysis of caspase-mediated suppression of the cGAS/STING pathway in Kaposi's sarcoma associated herpesvirus lytic infection reveals a dramatic cellular heterogeneity in type I interferon responses
Kaposi's sarcoma-associated herpesvirus (KSHV) utilizes the NDP52/CALCOCO2 selective autophagy receptor to disassemble processing bodies Acetyltransferases GCN5 and PCAF are required for B lymphocyte maturation in mice Optimization of avian perching manoeuvres Living with high potassium: how plants balance nutrient acquisition during K-induced salt stress First detection of herpesvirus and frequency of mycoplasma infection in free-ranging Hermann s tortoises (Testudo hermanni), and in potential pet vectors Depletion of Sun1/2 induces heterochromatin accrual in mesenchymal stem cells during adipogenesis Orientation dependent proton transverse relaxation in the human brain white matter: The magic angle effect on a cylindrical helix Cell-specific Bioorthogonal Tagging of Glycoproteins Placental uptake and metabolism of 25(OH)Vitamin D determines its activity within the fetoplacental unit CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation. A meta-analysis of transcriptomic profiles from Huntington's disease patients points to a pathophysiological role of CDC42, NFY, DLX1 and PRMT3 Fatal COVID-19 ARDS associated with incomplete AEC1 differentiation from the transitional state without senescence or fibrosis Citation needed? Wikipedia and the COVID-19 pandemic Including imprecisely georeferenced specimens improves accuracy of species distribution models and estimates of niche breadth: Don't let the perfect be the enemy of the good Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Dynamic interaction of BcsD subunit in type I bacterial cellulose synthase The compound of baicalein, wogonin, and oroxylin-A inhibits EMT in A549 cell line via PI3K/AKT-TWIST1-glycolysis pathway Non-invasive imaging of gene expression and protein secretion dynamics in living mice uncovers ectopic prothrombin expression as driver of thrombosis in cancer Modeling miRNA-driven post-transcriptional regulation by using exon-intron split analysis (EISA) in pigs Earliest photic zone niches probed by ancestral microbial rhodopsins Identifying complex sequence patterns in massive omics data with a variable-convolutional layer in deep neural network Time- and cell-dependent atypia and cell death are caused by progressive deficiency in DNA replication The Temporal Statistics of Musical Rhythm across Western Genres: An Amplitude Modulation Phase Hierarchy Model A Eukaryotic Circuit for Secretion-coupled Cellular Autonomy