Circulating SARS-CoV-2 variants B.1.1.7, 501Y.V2, and P.1 have gained ability to utilize rat and mouse Ace2 and altered in vitro sensitivity to neutralizing antibodies and ACE2-Ig
Distribution, molecular evolution, and mutational scanning of the anti-CRISPR family AcrIF7 reveal conservation, key residues for the protein function and a putative alternative binding mode to Cas8f
14-3-3ζ constrains insulin secretion by regulating mitochondrial function in pancreatic β-cells Balancing sensitivity and specificity in preclinical research An environmentally responsive transcriptional state modulates cell identities during root development LPS-TLR4 pathway exaggerates alcohol-induced acute-on-chronic liver failure via provoking NETs formation Identification of CD4+ Sub-population of Resident Cardiac Fibroblasts Linked to Myocardial Fibrosis The female pheromone (Z)-4-undecenal mediates flight attraction and courtship in Drosophila melanogaster Polycomb suppresses a female gene regulatory network to ensure testicular differentiation Evolution of phenotypic variance during adaptation to high temperature in Drosophila Centriole distal-end proteins CP110 and Cep97 influence centriole cartwheel growth at the proximal-end Optogenetic actuator/ERK biosensor circuits identify MAPK network nodes that shape ERK dynamics Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates survival of developing retinal neurons Glucose dynamics during ozone exposure measured using radiotelemetry: Stress drivers Pyroptosis-related gene signatures can robustly diagnose skin cutaneous melanoma and predict the prognosis Spatial proteomics reveals subcellular reorganization in human keratinocytes exposed to UVA light TNFα increases Tyrosine Hydroxylase expression in human monocytes Individual-based multiple-unit dissimilarity: novel indices and null model for assessing temporal variability in community composition Design, Mutate, Screen: High-throughput creation of genetic clocks with different period-amplitude characteristics First evidence of in vitro cytotoxic effects of marine microlitter on Merluccius merluccius and Mullus barbatus, two Mediterranean commercial fish species Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Force-correction Analysis Method for Derivation of Multidimensional Free Energy Landscapes from Adaptively Biased Replica Simulations Avian haemosporidians (Plasmodium and Haemoproteus) status in selected bird groups (Old world Flycatchers, Warblers, Babblers, and Thrushes) of India and their phylogenetic relationships with other lineages of the world Experimental evolution in TP53 deficient human gastric organoids recapitulates tumorigenesis Comparative Analysis of non-coding small-RNAs in Pseudomonas aeruginosa Keratitis Strains with Different Antibiotic Susceptibility Stimulus manipulations permit activation of fiber subpopulations in the mouse and rat vagus