De novo identification of maximally deregulated subnetworks based on multi-omics data with DeRegNet
A flux-based machine learning model to simulate the impact of pathogen metabolic heterogeneity on drug interactions
Host phenology regulates ecological and eco-evolutionary feedbacks underlying parasite-host demographic cycles Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Enhancement of CRISPR-mediated homologous recombination-based gene knock-in efficiency by simultaneous HDR overexpression and NHEJ suppression in poplar Single molecule studies reveal branched pathways for activator-dependent assembly of RNA polymerase II pre-initiation complexes The M1 and pre-M1 segments contribute differently to ion selectivity in ASICs and ENaCs Vapor exposure to Δ9-tetrahydrocannabinol (THC) slows locomotion of the Maine Lobster (Homarus americanus) Preprints in motion: tracking changes between preprint posting and journal publication during a pandemic Constraints on the evolution of toxin-resistant Na,K-ATPases have limited dependence on sequence divergence Stitching and registering highly multiplexed whole slide images of tissues and tumors using ASHLAR Implicating Gene and Cell Networks Responsible for Differential COVID-19 Host Responses via an Interactive Single Cell Web Portal Oxytocin promotes social grooming in bonobos Pseudomonas aeruginosa C-terminal processing protease CtpA assembles into a hexameric structure that requires activation by a spiral-shaped lipoprotein binding partner Intracranial human recordings reveal intensity coding for the pain of others in the insula Maternal microbiota Bifidobacterium promotes placental morphogenesis, nutrient transport and fetal growth in mice INPP4B drives lysosome biogenesis to restrict leukemic stem cell differentiation and promote leukemogenesis Artificial seawater based long-term culture of colonial ascidians Ecology of active viruses and their bacterial hosts in frozen Arctic peat soil revealed with H218O stable isotope probing metagenomics The Temporal Statistics of Musical Rhythm across Western Genres: An Amplitude Modulation Phase Hierarchy Model Pathfinder: A gamified measure to integrate general cognitive ability into the biological, medical, and behavioural sciences A Hierarchy of Biomolecular Proportional-Integral-Derivative Feedback Controllers for Robust Perfect Adaptation and Dynamic Performance Comparative Analysis of T Cell Spatial Proteomics and the Influence of HIV Expression ALLOPURINOL BLOCKS THE AORTIC ANEURYSM IN A MOUSE MODEL OF MARFAN SYNDROME VIA REDUCING AORTIC OXIDATIVE STRESS Active enhancers strengthen insulation by RNA-mediated CTCF binding at TAD boundaries Size dependent regeneration capacity of functionalized Capra ear derived micro-tissue scaffolds for treatment of cartilage defects