A memetic algorithm enables efficient local and global all-atom protein-protein docking with backbone and sidechain flexibility
CloneSig can jointly infer intra-tumor heterogeneity and mutational signature activity in bulk tumor sequencing data
P2X2 receptor subunit interfaces are missense variant hotspots where mutations tend to increase apparent ATP affinity The RAG1 Ubiquitin Ligase Domain Enhances Assembly and Selection of T Cell Receptor Genes to Restrain the Autoimmune Hazard of Generating T Cell Receptor Diversity Analysis of science journalism reveals gender and regional disparities in coverage Micro topographical instruction of bacterial attachment, biofilm formation and in vivo host response Combined epigenetic and metabolic inhibition blocks platinum-induced ovarian cancer stem cell enrichment The salivary microbiome shows a high prevalence of core bacterial members yet variability across human populations Hydrophobic mismatch is a key factor in protein transport on the Tat pathway Mitochondrial genomes of two parasitic Cuscuta species lack clear evidence of horizontal gene transfer and retain unusually fragmented ccmFC genes Design, Mutate, Screen: High-throughput creation of genetic clocks with different period-amplitude characteristics Compression for population genetic data through finite-state entropy E156G and Arg158, Phe-157/del mutation in NTD of spike protein in B.1.617.2 lineage of SARS-CoV-2 leads to immune evasion through antibody escape TSC22D4 interacts with Akt1 in response to metabolic and stress signals Leaf Aqueous Extract of Manilkara hexandra influenced Glucose Metabolism in fish: An observation with Labeo rohita Fingerlings as model organism Spatial control of cell division by GA-OsGRF7/8 module in a leaf explains the leaf length variation between cultivated and wild rice Repeated subfunctionalization of a modular antimicrobial peptide gene for neural function Second Heart Field-derived Cells Contribute to Angiotensin II-mediated Ascending Aortopathies First Report of Lactoria cornuta from Karnataka, West coast of India, Role of tropical cyclones in Range Extension Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes Blebbistatin protects iPSC-CMs from hypercontraction and facilitates automated patch-clamp based electrophysiological study Global connectivity fingerprints predict the domain generality of multiple-demand regions Hnf1b-CreER causes efficient recombination of a Rosa26-RFP reporter in duct and islet δ cells Scaling effects of temperature on parasitism from individuals to host-parasite systems Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition A terrain treadmill to study animal locomotion through large obstacles