Distribution, molecular evolution, and mutational scanning of the anti-CRISPR family AcrIF7 reveal conservation, key residues for the protein function and a putative alternative binding mode to Cas8f
Limited Phylogenetic Overlap Between Fluoroquinolone-Resistant Escherichia coli Isolated on Dairy Farms and those Causing Bacteriuria in Humans Living in the Same Geographical Region
A novel two-generation approach to the population dynamics of gregarious parasitoids The plant-specific DDR factor SOG1 increases chromatin mobility in response to DNA damage Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: the Multi-Targeting Drug DREAM Challenge Probing Patterning in Microbial Consortia with picCASO: a Cellular Automaton for Spatial Organisation FACT regulates pluripotency through distal regulation of gene expression in murine embryonic stem cells A chromosome-level genome assembly of a maize elite breeding line Dan340 Ineffectual AEC1 differentiation from KRT8hi transitional state without fibrosis is associated with fatal COVID-19 ARDS Membrane-catalyzed aggregation of islet amyloid polypeptide is dominated by secondary nucleation Comparative proteome signatures of trace samples by multiplexed Data-Independent Acquisition The longevity response to warm temperature is neurally controlled via the regulation of collagen genes Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Engineered bacteria detect tumor DNA Analysis of science journalism reveals gender and regional disparities in coverage TFAP2 paralogs facilitate chromatin access for MITF at pigmentation genes but inhibit expression of cell-cell adhesion genes independently of MITF Plant biomechanics and resilience to environmental changes are controlled by specific lignin chemistries in each vascular cell type and morphotype Simultaneous dual recordings from vestibular hair cells and their calyx afferents demonstrate multiple modes of transmission at these specialized endings Fitness-related traits are maximized in recently introduced, slow-growing populations of a global invasive clam Local fitness and epistatic effects lead to distinct patterns of linkagedisequilibrium in protein-coding genes Hierarchical autoencoder-based integration improves performance in multi-omics cancer survival models through soft modality selection Detection and functional resolution of soluble multimeric immune complexes by a comprehensive FcγR reporter cell panel NPEPPS regulates intracellular import and sensitivity to cisplatin by interaction with volume regulated anion channels High-throughput variant detection using a color-mixing strategy Extracellular Matrix Hydrogels Promote Expression of Muscle-Tendon Junction Proteins Foraging with friends, moving with anyone: effects of the social environment on movement-integrated habitat selection