Early postnatal activation of the hypoxia pathway disrupts β-cell function
Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects
Analysis of science journalism reveals gender and regional disparities in coverage Rescue of stalled clathrin-mediated endocytosis by asymmetric Arp2/3-mediated actin assembly Joint interactions with humans may pose a higher risk of zoonotic outbreaks than interactions with conspecifics among wildlife populations at human-wildlife interfaces The RAG1 Ubiquitin Ligase Domain Enhances Assembly and Selection of T Cell Receptor Genes to Restrain the Autoimmune Hazard of Generating T Cell Receptor Diversity Systematic monitoring of 2-Cys peroxiredoxin-derived redox signals unveiled its role in attenuating carbon assimilation rate The Hippocampus uses cryptographic principles rather than plasticity to enable animals to secretly cache and retrieve their food Glucose inhibits haemostasis and accelerates diet-induced hyperlipidaemia in zebrafish larvae A network approach to genetic circuit designs Overexpression-based detection of translatable circular RNAs is vulnerable to coexistent linear RNA byproducts Functional binding dynamics relevant to the evolution of zoonotic spillovers in endemic and emergent Betacoronavirus strains A thermodynamic model for water activity and redox potential in evolution and development A mixture of innate cryoprotectants is key for freeze tolerance and cryopreservation of a drosophilid fly larva. F1F0 ATP Hydrolysis is a Determinant of Metabolic Rate, a Correlate of Lifespan, and a Weakness of Cancer Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Rad51 filaments assembled in the absence of the complex formed by the Rad51 paralogs Rad55 and Rad57 are outcompeted by translesion DNA polymerases on UV-induced ssDNA gaps The Telomere Length Landscape of Prostate Cancer A repertoire of foraging decision variables in the mouse brain Frequency modulated timer regulates mammalian hibernation Activation of the type 3 secretion system of enteropathogenic E. coli leads to remodeling of its membrane composition and function Chemotherapy coupled to macrophage inhibition leads to enhanced T and B cell infiltration and durable triple negative breast cancer regression Humanized substitutions of Vmat1 in mice alter amygdala-dependent behaviors associated with the evolution of anxiety Nontypeable Haemophilus influenzae infection impedes Pseudomonas aeruginosa colonization and persistence in mouse respiratory tract Pyroptosis-related gene signatures can robustly diagnose skin cutaneous melanoma and predict the prognosis Spatio-temporal, optogenetic control of gene expression in organoids