Visualization of loop extrusion by DNA nanoscale tracing in single human cells
A NANOG-pERK reciprocal regulatory circuit mediates Nanog autoregulation and ERK signaling dynamics.
Inhibitors of ERp44, PDIA1, and AGR2 induce disulfide-mediated oligomerization of Death Receptors 4 and 5 and cancer cell death High Spatial Resolution MALDI Imaging Mass Spectrometry ofFresh-Frozen Bone Ecology of active viruses and their bacterial hosts in frozen Arctic peat soil revealed with H218O stable isotope probing metagenomics Using total RNA quality metrics for time since deposition estimates in degrading bloodstains Loss of histone methyltransferase SETD1B in oogenesis results in the redistribution of genomic histone 3 lysine 4 trimethylation Long-read and chromosome-scale assembly of the hexaploid wheat genome achieves high resolution for research and breeding Resolving when (and where) the Thylacine went extinct "Adopt a Microorganism" methodology enhances the discourse richness of high school students in both hybrid learning and remote education Human centromere formation activates transcription and opens chromatin fibre structure Establishing farm dust as a useful viral metagenomic surveillance matrix Characterising ontogeny of numerosity discrimination in zebrafish reveals the use of multiple, numerical and non- numerical mechanisms. Neutralization of SARS-CoV-2 Omicron BA.2 by Therapeutic Monoclonal Antibodies Synthetic periphyton as a model system to understand species dynamics in complex microbial freshwater communities A novel method for producing functionalized vesicles that efficiently deliver oligonucleotides in vitro in cancer cells and in vivo in mice Ineffectual AEC1 differentiation from KRT8hi transitional state without fibrosis is associated with fatal COVID-19 ARDS Fitness-related traits are maximized in recently introduced, slow-growing populations of a global invasive clam Distinguishing excess mutations and increased cell death based on variant allele frequencies Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium Neural Representations of Food-Related Attributes in the Human Orbitofrontal Cortex During Choice Deliberation in Anorexia Nervosa Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Spontaneous differentiation leads to emergence of hybrid cell states relate to poor prognosis in oral cancer Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation High performance single-cell gene regulatory network inference at scale: The Inferelator 3.0 Cytokinin oxidase/dehydrogenase family genes exhibit functional divergence and overlap in rice growth and development