Profiles of expressed mutations in single cells reveal subclonal expansion patterns and therapeutic impact of intratumor heterogeneity
BatchDTA: Implicit batch alignment enhances deep learning-based drug-target affinity estimation
Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Effect of a low concentration in chloride, sodium and potassium on oocyte maturation, oocyte hydration, ovulation and egg quality in rainbow trout. Strong immobilization of C. elegans en masse on cultivation plates by thermoelectric cooling for high-throughput submicron-resolution microscopy From adverse to beneficial - contrasting dietary effects of freshwater mixotrophs on zooplankton Whole-genome sequencing analysis of wild-caught house mice Mus musculus from Madagascar Quantifying the Morphology and Mechanisms of Cancer Progression in 3D in-vitro environments: Integrating Experiments and Multiscale Models Propelling and perturbing appendages together facilitate strenuous ground self-righting Meningeal dendritic cells-astrocytes interactions elevate the kynurenine metabolic pathway to sustain neuropathic pain Changes in Behavior and Salivary Serum Amyloid A in cows with Subclinical Mastitis Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: the Multi-Targeting Drug DREAM Challenge Prediction of the sex-determination gene in tunas (Thunnus fishes) Loss of Nuclear DNA Ligase III Reverts PARP Inhibitor Resistance in BRCA1/53BP1 Double-deficient Cells by Exposing ssDNA Gaps Creatine transporter deficient rat model show motor dysfunction, cerebellar alterations and muscle creatine deficiency without muscle atrophy Towards a unified model of naive T cell dynamics across the lifespan A high throughput lipidomics method using scheduled multiple reaction monitoring "Adopt a Microorganism" methodology enhances the discourse richness of high school students in both hybrid learning and remote education Deficiency of gluconeogenic enzyme PCK1 promotes murine NASH progression and fibrosis by activation PI3K/AKT/PDGF axis METHYLOME DYNAMICS UPON PROTEASOME INHIBITION BY THE PSEUDOMONAS VIRULENCE FACTOR SYRINGOLIN A Transient accumulation, bidirectional movement and tip release of KIF13B in primary cilia PAK1 and PAK2 in cell metabolism regulation Robust retrieval of data stored in DNA by de Bruijn graph-based de novo strand assembly Modelling homing suppression gene drive in haplodiploid organisms Functional evaluation of the P681H mutation on the proteolytic activation the SARS-CoV-2 variant B.1.1.7 (Alpha) spike FGF8-mediated signaling regulates tooth developmental pace during odontogenesis