An ALS-associated mutant KIF5A forms oligomers and aggregates and induces neuronal toxicity
The spindle assembly checkpoint and the spatial activation of Polo kinase determine the duration of cell division and prevent neural stem cells tumor formation
Neuroinvasion and neurotropism by SARS-CoV-2 variants in the K18-hACE2 mouse Juvenile Gouldian Finches (Erythrura gouldiae) form sibling sub-groups during social integration Ultrahigh-Throughput Ambient MS: Direct Analysis at 22 Samples per Second by Infrared Matrix-Assisted Desorption Electrospray Ionization Mass Spectrometry An Evolutionary Process Without Variation and Selection An Extended Motif in the SARS-CoV-2 Spike Modulates Binding and Release of Host Coatomer in Retrograde Trafficking The Consequences of Differential Origin Licensing Dynamics in Distinct Chromatin Environments Fixed or random? On the reliability of mixed-effects models for a small number of levels in grouping variables First evidence of in vitro cytotoxic effects of marine microlitter on Merluccius merluccius and Mullus barbatus, two Mediterranean commercial fish species GeneCup: mine PubMed for gene relationships using custom ontology and deep learning Capturing the interplay of membrane lipids and structural transitions in human ABCA7 Inferring mammalian tissue-specific regulatory conservation by predicting tissue-specific differences in open chromatin Preprints in motion: tracking changes between preprint posting and journal publication during a pandemic Multiple brace root phenotypes promote anchorage and limit root lodging in maize Multi-layered regulation of neuroectoderm differentiation by retinoic acid in a primitive streak-like context Modeling predicts differences in CAR T cell signaling due to biological variability Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation Establishing combination PAC-1 and TRAIL regimens for treating ovarian cancer based on patient-specific pharmacokinetic profiles using in silico clinical trials OrganoID: a versatile deep learning platform for tracking and analysis of single-organoid dynamics Immunogenicity and protective efficacy of a highly thermotolerant, trimeric SARS-CoV-2 receptor binding domain derivative Immunogenicity of SARS-CoV-2 trimetric spike protein associated to Poly(I:C) plus Alum Genomic evidence of paternal genome elimination in the globular springtail Allacma fusca Data-Driven Network Models for Genetic Circuits From Time-Series Data with Incomplete Measurements Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Emerging experience-dependent dynamics in primary somatosensory cortex reflect behavioral adaptation