Optogenetic actuator/ERK biosensor circuits identify MAPK network nodes that shape ERK dynamics
Localization of signaling receptors maximizes cellular informationacquisition in spatially-structured natural environments
Ending animal agriculture would stabilize greenhouse gas levels for 30 years and offset 70 percent of CO2 emissions this century A Proteome-Wide Map of Chaperone-Assisted Protein Refolding in the Cytosol Topographic projection of retinal ganglion cell axons at single-cell precision underlies retinotopy in the mouse superior colliculus Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition IRI-CCE: A Platform for Evaluating CRISPR-based Base Editing Tools and Its Components Comprehensive analysis of pyroptosis-associated in molecular classification, immunity and prognostic of glioma A General Biphasic-Bodyweight Model for Scaling Basal Metabolic Rate, Glomerular Filtration Rate and Drug Clearance from Birth to Adulthood The combined treatment of Molnupiravir and Favipiravir results in a marked potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model Chromosomal rearrangements with stable repertoires of genes and transposable elements in an invasive forest-pathogenic fungus caliPER: A software for blood-free parametric Patlak mapping using PET/MRI input function. Non-specific effects of a CINNAMATE-4-HYDROXYLASE inhibitor on auxin homeostasis A noble TGF beta biogenesis inhibitor exhibits both potent anti-fibrotic and anti-inflammatory capabilities An Extended Motif in the SARS-CoV-2 Spike Modulates Binding and Release of Host Coatomer in Retrograde Trafficking Chromosome fusion affects genetic diversity and evolutionary turnover of functional loci, but consistently depends on chromosome size A new method for the sampling and preservation of placental specimens in low-resource settings for the identification of P. falciparum and analysis of nucleic acids First evidence of in vitro cytotoxic effects of marine microlitter on Merluccius merluccius and Mullus barbatus, two Mediterranean commercial fish species Liver environment-imposed constraints diversify movement strategies of liver-localized CD8 T cells Integrative transcriptomics reveals ectopic lipid homeostasis mechanisms in non-endocrine cells of the teleost pituitary A tool for assessing alignment of biomedical data repositories with open, FAIR, citation and trustworthy principles Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects A Bayesian model selection approach to mediation analysis A network approach to genetic circuit designs Different contribution of the monkey prefrontal and premotor dorsal cortex in decision making during a transitive inference task SufB intein splicing in Mycobacterium tuberculosis is influenced by two remote conserved N-extein Histidines