Ecological Differentiation Among Globally Distributed Lineages of the Rice Blast Fungus Pyricularia oryzae
Delayed but generalist resistance in alternation: a trade-off shaped by the mode of action of antifungals, as revealed by experimental evolution in a plant pathogen.
Inhibitors of ERp44, PDIA1, and AGR2 induce disulfide-mediated oligomerization of Death Receptors 4 and 5 and cancer cell death Dysfunction of an energy sensor NFE2L1 triggers uncontrollable AMPK signal and glucose metabolism reprogramming Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Antibacterial potency of Type VI amidase effector toxins is dependent on substrate topology and cellular context The number of cytokinesis nodes in mitotic fission yeast scales with cell size Live imaging YAP signaling in mouse embryo development Confronting population models with experimental microcosm data: from trajectory matching to state-space models Quantifying the Morphology and Mechanisms of Cancer Progression in 3D in-vitro environments: Integrating Experiments and Multiscale Models A unified mechanism for innate and learned visual landmark guidance in the insect central complex Naming of human diseases on the wrong side of history Design, immunogenicity and efficacy of a Pan-SARS-CoV-2 synthetic DNA vaccine Slowing down an analyte in a nanopore Chromosome breaks in breast cancers occur near herpes tumor virus sequences and explain why cancer drugs stop working Multiple brace root phenotypes promote anchorage and limit root lodging in maize Conserved organ-specific microbial assemblages in different populations of a terrestrial crab Antibiotic Resistance Genes and Taxa Analysis from Mat and Planktonic Microbiomes of Antarctic Lake Fryxell and Lake Bonney, and a Mat-forming Culture of Rhodoferax antarcticus Small extracellular vesicles from young mice prevent frailty, improve healthspan and decrease epigenetic age in old mice. Structural basis of anti-SARS-CoV-2 activity of HCQ: specific binding to N protein to disrupt its interaction with nucleic acids and LLPS Transcriptome-informed reduction of protein databases: an analysis of how and when proteogenomics enhances eukaryotic proteomics SERCA function is impaired in skeletal and cardiac muscles from young DBA/2J mdx mice Bulk-assembly of monodisperse coacervates and giant unilamellar vesicles with programmable hierarchical complexity Sequencing of methylase-accessible regions in integral circular extrachromosomal DNA reveals differences in chromatin structure. Quantitative analysis of gene expression on the inactive human X chromosome Oscillations support short latency co-firing of neurons during human episodic memory formation.