LCK Regulates Homologous Recombination DNA Repair Identifying a New Therapeutic Target for Sensitizing PARP Inhibitors in HR Proficient Ovarian Cancer
BRPF3 knockdown or inhibition moderately reverses olaparib resistance in high grade serous ovarian carcinoma
The isoforms of pyruvate kinase act as nutrient sensors for the β-cell KATP channel Remarked Suppression of Aβ42 Protomer-protomer Dissociation Reaction via Pentamer Dimerization Elucidated by Molecular Dynamics Simulation Enhancers regulate 3' end processing activityto control expression of alternative 3'UTR isoforms Regulatory perturbations of ribosome allocation optimize the growth proteome with a trade-off in adaptation capacity Identifying critical transcriptional targets of the MYC oncogene using a novel competitive precision genome editing (CGE) assay BioCAT: a novel tool to search biosynthetic gene clusters producing nonribosomal peptides with a known structure Fitness-related traits are maximized in recently introduced, slow-growing populations of a global invasive clam Using total RNA quality metrics for time since deposition estimates in degrading bloodstains Analysis of science journalism reveals gender and regional disparities in coverage Clp protease and antisense RNA jointly regulate the global regulator CarD to mediate mycobacterial starvation response Aberrant induction of p19Arf-mediated cellular senescence contributes to neurodevelopmental defects Depletion of Sun1/2 induces heterochromatin accrual in mesenchymal stem cells during adipogenesis Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition The first genotypic fitness network in a vertebrate reveals that hybridization increases access to novel fitness peaks NUCLEAR RETENTION OF LEPTIN/UPD2 REGULATES ORGANISMAL RESILIENCE TO NUTRIENT EXTREMES The Inflammatory Role of Milk Fat Globule Epidermal Growth Factor VIII in Angiotensin II Induced Arterial Remodeling An environmentally responsive transcriptional state modulates cell identities during root development Robust retrieval of data stored in DNA by de Bruijn graph-based de novo strand assembly Contribution of arm movements to balance recovery after tripping in older adults. Autoantibodies against Progranulin and IL-1 receptor antagonist due to immunogenic posttranslational isoforms contribute to hyperinflammation in critically ill COVID-19 Anticipatory regulation of cardiovascular system on emergence of auditory-motor interaction in young infants Frequency modulated timer regulates mammalian hibernation Assigning metabolic rate measurements to torpor and euthermy in heterothermic endotherms: 'torpor', a new package for R. Cellular feedback to organotelluranes displays modulation of antioxidant proteins gene expression