Using Topological Data Analysis and RRT to Investigate Protein Conformational Spaces
Exploratory analysis of multiple traits co-adaptations in the population history
Quantitative analysis of gene expression on the inactive human X chromosome In vitro synthesis and reconstitution using mammalian cell-free lysates enables the systematic study of the regulation of LINC complex assembly Generation of nonlinear and spatially-organized 3D cultures on a microfluidic chip using photoreactive thiol-ene and methacryloyl hydrogels Venomics and antivenomics of Indian spectacled cobra (Naja naja) from the Western Ghats Environmental control of Pub1 (NEDD4 family E3 ligase) in S. pombe is regulated byTORC2 and Gsk3. Mitochondrial pyruvate supports lymphoma proliferation by fueling a non-canonical glutamine metabolism pathway Strength of interactions in the Notch gene regulatory network determines patterning and fate in the notochord Large protein complex interfaces have evolved to promote cotranslational assembly Risky choice: probability weighting explains Independence Axiom violations in monkeys Deep inference of seabird dives from GPS-only records: performance and generalization properties Conformational decoupling in acid-sensing ion channels uncovers mechanism and stoichiometry of PcTx1-mediated inhibition RORγt serine 182 tightly regulates T cell heterogeneity to maintain mucosal homeostasis and restrict tissue inflammation Genome-wide local ancestry and direct evidence for mitonuclear coadaptation in African hybrid cattle populations (Bos taurus/indicus) SERCA function is impaired in skeletal and cardiac muscles from young DBA/2J mdx mice TAS-Seq: a robust and sensitive amplification method for bead-based scRNA-seq Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition First detection of herpesvirus and frequency of mycoplasma infection in free-ranging Hermann s tortoises (Testudo hermanni), and in potential pet vectors A causal test of affect processing bias in response to affect regulation Unevolved proteins from modern and prebiotic amino acids manifest distinct structural profiles Higher-order effects, continuous species interactions, and trait evolution shape microbial spatial dynamics Multi-omic analysis of the Arabidopsis clock activator mutant rve 4 6 8 reveals connections to carbohydrate metabolism and proteasome regulation Targeting conserved sequences circumvents the evolution of resistance in a viral gene drive against human cytomegalovirus ZIKV disrupts placental ultrastructure and drug transporter expression in mice Naming of human diseases on the wrong side of history