Nutrient and salt depletion synergistically boosts glucose metabolism in individual bacteria
Mobile element integration reveals a chromosome dimer resolution system in Legionellales.
Unevolved proteins from modern and prebiotic amino acids manifest distinct structural profiles Hypomyelination reduces parvalbumin interneuron density and auditory cortex inhibitory function A tool for assessing alignment of biomedical data repositories with open, FAIR, citation and trustworthy principles Improved detection of evolutionary selection highlights potential bias from different sequencing strategies in complex genomic-regions The important choice of reference environment in microevolutionary climate response predictions Thermodynamics and kinetics of aggregation of flexible peripheral membrane proteins Linked machine learning classifiers improve species classification of fungi when using error-prone long-reads on extended metabarcodes Dietary palmitic acid induces innate immune memory via ceramide production that enhances severity of acute septic shock and clearance of infection Cellular-level phenotyping of tumor-immune microenvironment (TiME) in patients in vivo reveals distinct inflammation and endothelial anergy signatures Social integration predicts survival in female white-faced capuchin monkeys Structural basis for cell-type specific evolution of viral fitness by SARS-CoV-2 Genomics-based deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid AHR signaling dynamics. Genomic regions associate with major axes of variation driven by gas exchange and leaf construction traits in cultivated sunflower (Helianthus annuus L.) A novel Boolean network inference strategy to model early hematopoiesis aging Human 14-3-3 proteins site-selectively bind the mutational hotspot region of SARS-CoV-2 nucleoprotein modulating its phosphoregulation A chemical screen based on an interruption of zebrafish gastrulation identifies the HTR2C inhibitor Pizotifen as a suppressor of EMT-mediated metastasis Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Plasmodium DDI1 is a potential dual-therapeutic target and essential chromatin-associated protein Small extracellular vesicles from young mice prevent frailty, improve healthspan and decrease epigenetic age in old mice. Apolipoprotein M attenuates anthracycline cardiotoxicity and lysosomal injury Rho Kinase regulates neutrophil NET formation that is involved in UVB-induced skin inflammation Changes in Behavior and Salivary Serum Amyloid A in cows with Subclinical Mastitis A northern range extension of a Canadian species of Special Concern, Dielis pilipes (Hymenoptera: Scoliidae), in the Okanagan Valley of British Columbia Spatio-temporal, optogenetic control of gene expression in organoids