Mechanistic basis for understanding the dual activities of the bifunctional Azotobacter vinelandii mannuronan C-5 epimerase and alginate lyase AlgE7
TNFa-induced LDL cholesterol accumulation involve elevated LDLR cell surface levels and SR-B1 downregulation in human arterial endothelial cellsan arterial endothelial cells
Diverse classes of constraints enable broader applicability of a linear programming-based dynamic metabolic modeling framework Distinct cellular origins and differentiation process account for distinct oncogenic and clinical behaviors of leiomyosarcomas Autophagosomes fuse to phagosomes and facilitate the degradation of apoptotic cells in Caenorhabditis elegans Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition A nontoxic tetrodotoxin analog, 5,6,11-trideoxytetrodotoxin, as an olfactory chemoattractant for the grass puffer A rationalized definition of tumor suppressor microRNAsexcludes miR-34a Hundreds of viral families in the healthy infant gut Synthetic periphyton as a model system to understand species dynamics in complex microbial freshwater communities Bioactive constituents of Verbena officinalis regulate killing efficiency of primary human natural killer cells by accelerating killing processes Navigating the amino acid sequence space between functional proteins using a deep learning framework Cross-species incompatibility between a DNA satellite and the Drosophila Spartan homolog poisons germline genome integrity Glutathione regulates transcriptional activation of iron transporters via S-nitrosylation of bHLH factors to modulate subcellular iron homeostasis Bone mineral density modeling via random field: normality, stationarity, sex and age dependence CandyCollect: At-home saliva sampling for capture of respiratory pathogens Energy efficient network activity from disparate circuit parameters Genomic evidence of paternal genome elimination in the globular springtail Allacma fusca GPI-anchored FGF directs cytoneme-mediated bidirectional signaling to self-regulate tissue-specific dispersion IRGM/Irgm1 Aggravates Progression of Atherosclerosis by Inducing Macrophage Apoptosis through the MAPK Signaling Pathway Preprints in motion: tracking changes between preprint posting and journal publication during a pandemic Neurological mechanism of sensory deficits after developmental exposure to non-dioxin-like polychlorinated biphenyls (PCBs) in zebrafish larvae Linking null models to hypotheses to improve nestedness analysis A Wnt/β-catenin signaling driven adipocyte population required for beiging and glucose homeostasis Engineering of a fluorescent chemogenetic reporter with tunable color for advanced live-cell imaging Barbary ground squirrels do not have a sentinel system but instead synchronise vigilance