RIG-I immunotherapy overcomes radioresistance in p53-positive malignant melanoma
Immune complex solubility and size govern Fc-gamma receptor responses: A scalable cell-based reporter system
Laminar compartmentalization of attention modulation in area V4 aligns with the demands of visual processing hierarchy in the cortex Mechanical loading of cranial joints minimizes the craniofacial phenotype in Crouzon syndrome Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Detection of ancestry-derived variants of modern Japanese revealed the formation process of regional gradations of the current Japanese archipelago population Sequence features of retrotransposons allow for epigenetic variability Flexible reprogramming of Pristionchus pacificus motivation for attacking Caenorhabditis elegans in predator-prey competition Usutu virus escapes langerin-induced restriction to productively infect human Langerhans cells, unlike West Nile virus. Distinct cellular origins and differentiation process account for distinct oncogenic and clinical behaviors of leiomyosarcomas The interaction of physical structure and nutrient loading drives ecosystem change in a large tropical lake over 40 years Preprints in motion: tracking changes between preprint posting and journal publication during a pandemic Low dose rate γ-irradiation protects Drosophila melanogaster chromosomes from double strand breaks and telomere fusions by modulating the expression of the esi-RNA biogenesis factor Loquacious. Structural predictions of the SNX-RGS proteins suggest they belong to a new class of lipid transfer proteins Morphology of immatures of the thelytokous ant, Monomorium triviale Wheeler (Formicidae: Myrmicinae: Solenopsidini) with descriptions of the extraordinary last-instar queen larvae Highly scaled measurements of C. elegans development suggest that physical constraints guide growth trajectories and animal shape LPS-TLR4 pathway exaggerates alcohol-induced acute-on-chronic liver failure via provoking NETs formation Non-Newtonian Blood Rheology Impacts Left Atrial Stasis in Patient-Specific Simulations Unevolved proteins from modern and prebiotic amino acids manifest distinct structural profiles TCAB1 prevents nucleolar accumulation of the telomerase RNA to promote telomerase assembly The structurome of a Clostridium difficile phage and the remarkable accurate prediction of its novel phage receptor-binding protein Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: the Multi-Targeting Drug DREAM Challenge G protein-coupled estrogen receptor activation by Bisphenol-A disrupts protection from apoptosis conferred by estrogen receptors ERα and ERβ in pancreatic beta cells Non-specific effects of a CINNAMATE-4-HYDROXYLASE inhibitor on auxin homeostasis Functional buffering via cell-specific gene expression promotes tissue homeostasis and cancer robustness CloneSig can jointly infer intra-tumor heterogeneity and mutational signature activity in bulk tumor sequencing data