Identifying Cross-Cancer Similar Patients via a Semi-Supervised Deep Clustering Approach
Drug-Target Binding Affinity Prediction Using Transformers
Hypothalamic GABRA5-positive Neurons Control Obesity via Astrocytic GABA Arabidopsis AtPME2 has a pH-dependent processivity and control cell wall mechanical properties Quantifying the Morphology and Mechanisms of Cancer Progression in 3D in-vitro environments: Integrating Experiments and Multiscale Models Quantifying ERK-activity in response to inhibition of the BRAFV600E-MEK-ERK cascade using mathematical modelling A CTP-dependent gating mechanism enables ParB spreading on DNA Balancing sensitivity and specificity in preclinical research Nuclear Progestin Receptor Mediated Linkage of Blood Coagulation and Ovulation A new method based on the von Mises-Fisher distribution shows that a minority of liver-localized CD8 T cells display hard-to-detect attraction to Plasmodium-infected hepatocytes Creatine transporter deficient rat model show motor dysfunction, cerebellar alterations and muscle creatine deficiency without muscle atrophy Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition The impact of housing conditions on mesenchymal stromal/stem cell populations differ between adipose tissue and skeletal muscle Embracing imperfection: machine-assisted invertebrate classification in difficult datasets Translation of upstream open reading frames does not trigger nonsense-mediated decay in Arabidopsis Highly scaled measurements of C. elegans development suggest that physical constraints guide growth trajectories and animal shape Structure-Functional-Selectivity Relationship Studies on A-86929 Analogs and Small biaryl Fragments toward Discovery of biased D1 agonists Rad51 filaments assembled in the absence of the complex formed by the Rad51 paralogs Rad55 and Rad57 are outcompeted by translesion DNA polymerases on UV-induced ssDNA gaps Engineered bacteria detect tumor DNA Ubiquity and origins of structural maintenance of chromosomes (SMC) proteins in eukaryotes Plucking a string or playing a G? Choice type impacts human reinforcement learning Spontaneous Chiral Symmetry Breaking in a Random Driven Chemical System Allosteric activation of SARS-CoV-2 RdRp by remdesivir triphosphate and other phosphorylated nucleotides Computation of the mitochondrial age distribution along the axon length Morphology of immatures of the thelytokous ant, Monomorium triviale Wheeler (Formicidae: Myrmicinae: Solenopsidini) with descriptions of the extraordinary last-instar queen larvae Rational Exploration of Fold Atlas for Human Solute Carrier Proteins