Dietary palmitic acid induces innate immune memory via ceramide production that enhances severity of acute septic shock and clearance of infection
Omicron BA.2 specifically evades broad sarbecovirus neutralizing antibodies
Super-enhancer signature reveals key mechanisms associated with resistance to non-alcoholicsteatohepatitis in humans with obesity Phases of cortical actomyosin dynamics coupled to the neuroblast polarity cycle Bulk-assembly of monodisperse coacervates and giant unilamellar vesicles with programmable hierarchical complexity Development of a Novel PROTAC using the Nucleic Acid Aptamer as a Targeting Ligand for Tumor Selective Degradation of Nucleolin Integration of the Salmonella Typhimurium methylome and transcriptome reveals DNA methylation and transcriptional regulation are largely decoupled under virulence-related conditions Prostaglandin EP3 Receptor signaling is required to prevent insulin hypersecretion and metabolic dysfunction in a non-obese mouse model of insulin resistance Tackling polypharmacology of kinase inhibitors and selecting chemical kinase probes by transcription factor activity profiling. TFAP2 paralogs facilitate chromatin access for MITF at pigmentation genes but inhibit expression of cell-cell adhesion genes independently of MITF Enhanced transcriptional heterogeneity mediated by NF-κB super-enhancers Comprehensive analysis of pyroptosis-associated in molecular classification, immunity and prognostic of glioma Feline tooth resorption findings from a questionnaire survey on 8115 Finnish cats and a case-control study for a more defined population drawn from the survey Extrasynaptic signaling enables an asymmetric juvenile motor circuit to produce a symmetric gait Investigation of Chordwise Functionally Graded Flexural Rigidity in Flapping Wings Using a Two-Dimensional Pitch-Plunge Model Analysis of science journalism reveals gender and regional disparities in coverage Genome-wide analysis of the non-coding RNA synthetic genetic network reveals extensive plasticity and unique phenotypes in yeast Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Morphology of immatures of the thelytokous ant, Monomorium triviale Wheeler (Formicidae: Myrmicinae: Solenopsidini) with descriptions of the extraordinary last-instar queen larvae Deep learning-based quantification of arbuscular mycorrhizal fungi in plant roots Long term analysis of social structure: evidence of age-based consistent associations in male Alpine ibex Targeting SARS-CoV-2 infection through CAR-T like bispecific T cell engagers incorporating ACE2 oCEM: Automatic detection and analysis of overlapping co-expressed gene modules Higher-order effects, continuous species interactions, and trait evolution shape microbial spatial dynamics Population bottleneck has only marginal effect on fitness evolution and its repeatability in dioecious C. elegans Evaluation of US state pollinator plans using 3 evidence-based policymaking frameworks