Drug screening at single-organoid resolution via bioprinting and interferometry
Production and characterization of virus-free, CRISPR-CAR T cells capable of inducing solid tumor regression
Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: the Multi-Targeting Drug DREAM Challenge LPS-TLR4 pathway exaggerates alcohol-induced acute-on-chronic liver failure via provoking NETs formation Bioactive constituents of Verbena officinalis regulate killing efficiency of primary human natural killer cells by accelerating killing processes Design, Mutate, Screen: High-throughput creation of genetic clocks with different period-amplitude characteristics Loss of Acta2 in cardiac fibroblasts does not prevent myofibroblast differentiation or affect cardiac repair after myocardial infarction iCn3D: From Web-based 3D Viewer to Structure Analysis Tool in Batch Mode ISL1 is necessary for auditory neuron development and tonotopic organization Immunogenicity and protective efficacy of a highly thermotolerant, trimeric SARS-CoV-2 receptor binding domain derivative A cell cycle-dependent GARP-like transcriptional repressor regulates the initiation of differentiation in Giardia lamblia Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Global Constraints within the Developmental Program of the Drosophila Wing Non-specific effects of a CINNAMATE-4-HYDROXYLASE inhibitor on auxin homeostasis Balancing sensitivity and specificity in preclinical research A MALDI-TOF assay identifies nilotinib as an inhibitor of inflammation in acute myeloid leukaemia Changes in Behavior and Salivary Serum Amyloid A in cows with Subclinical Mastitis A noble TGF beta biogenesis inhibitor exhibits both potent anti-fibrotic and anti-inflammatory capabilities A novel 5 prime DNA binding site in RFC facilitates PCNA loading for gap DNA repair Many ways to stick the landing: novel righting strategies allow spotted lanternfly nymphs to land on diverse substrates Outer hair cell electro-mechanical power conversion Conformist social learning leads to self-organised prevention against adverse bias in risky decision making The maize gene maternal derepression of r1 (mdr1) encodes a DNA glycosylase that demethylates DNA and reduces siRNA expression in endosperm Gene structure-based homology search identifies highly divergent putative effector gene family Unifying Single-Channel Permeability from Rare-Event Sampling and Steady-State Flux Selective Ablation of 3' RNA ends and Processive RTs Facilitate Direct cDNA Sequencing of Full-length Host Cell and Viral Transcripts