Ensovibep, a novel trispecific DARPin candidate that protects against SARS-CoV-2 variants
A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Comparison of hybrid learning and remote education in the implementation of the 'Adopt a Microorganism' methodology Combined docking and machine learning identifies key molecular determinants of ligand pharmacological activity on β2 adrenoceptor. Motor Protein MYO1C is Critical for Photoreceptor Opsin Trafficking and Visual Function Estrogen-related receptor alpha and Rplp1-dependent translation coordinately regulate starvation response and decrease NASH progression The OPAQUE1/DISCORDIA2 myosin XI is required for phragmoplast guidance during asymmetric cell division in maize Thermodynamic constraints on the assembly and diversity of microbial ecosystems are different near to and far from equilibrium Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition An epigenome atlas of neural progenitors within the embryonic mouse forebrain Ribosome actuator via the SpoT/ppGpp pathway to mitigate gene overexpression burden Chromosomal rearrangements with stable repertoires of genes and transposable elements in an invasive forest-pathogenic fungus Sound localization in world and head-centered space in ferrets Nuclear Progestin Receptor Mediated Linkage of Blood Coagulation and Ovulation CyanoHABs: unavoidable evolutionary ecological consequence for low nutrient-requiring cyanobacteria in eutrophic water A phenomics approach for in vitro antiviral drug discovery New Segmentation and Feature Extraction Algorithm for Classification of White Blood Cells in Peripheral Smear Images An epigenetic memory of inflammation controls context-dependent lineage plasticity in the pancreas Morphology of immatures of the thelytokous ant, Monomorium triviale Wheeler (Formicidae: Myrmicinae: Solenopsidini) with descriptions of the extraordinary last-instar queen larvae Nelfinavir markedly improves lung pathology in SARS-CoV-2-infected Syrian hamsters despite lack of an antiviral effect The biochemical resolving power of fluorescence lifetime imaging: untangling the roles of the instrument response function and photon-statistics Co-option of immune effectors by the hormonal signalling system triggering metamorphosis in Drosophila melanogaster Pore dynamics and asymmetric cargo loading in an encapsulin nanocompartment Genetic analysis of DinG-family helicase YoaA and its interaction with replication clamp-loader protein HolC in E. coli Hematopoietic differentiation is characterized by a transient peak of entropy at a single cell level.