BRPF3 knockdown or inhibition moderately reverses olaparib resistance in high grade serous ovarian carcinoma
Cellular Fitness Phenotypes of Cancer Target Genes from Oncobiology to Cancer Therapeutics
CsrA-controlled proteins reveal new dimensions of Acinetobacter baumannii desiccation tolerance Bulk-assembly of monodisperse coacervates and giant unilamellar vesicles with programmable hierarchical complexity Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Population differences in the length and early-life dynamics of telomeres among European pied flycatchers Synthetic antigen presenting cells reveal the diversity and functional specialisation of extracellular vesicles composing the fourth signal of T cell immunological synapses. Network Inference from Perturbation Time Course Data Electrical Stimulated GLUT4 Signaling Attenuates Critical Illness-Associated Muscle Wasting Time- and cell-dependent atypia and cell death are caused by progressive deficiency in DNA replication Global population genomics of two subspecies of Cryptosporidium hominis during 500 years of evolution SARS-CoV-2 Can Infect Human Embryos A Bayesian method to cluster single-cell RNA sequencing data using Copy Number Alterations An epigenomic shift in amygdala marks the transition to maternal behaviors in alloparenting virgin female mice Analysis of science journalism reveals gender and regional disparities in coverage Use of lignocellulosic residue from second-generation ethanol production to enhance methane production through co-digestion Creatine transporter deficient rat model show motor dysfunction, cerebellar alterations and muscle creatine deficiency without muscle atrophy Bacterial glycyl tRNA synthetase offers glimpses of ancestral protein topologies An integrative approach leads to the discovery of a novel anti-leukemic peptide from human milk EGFR inhibition leads to enhanced desmosome assembly and cohesion in cardiomyocytes BAG3 regulation of Rab35 mediates the Endosomal Sorting Complexes Required for Transport /endolysosome pathway and tau clearance Chromatin remodelling by INO80 at promoter proximal pause sites promotes premature termination of mRNA synthesis Global analysis of multi-mutants to improveprotein function Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir (PF-07321332) Text has been revised, image definition has been revised. Plant host shift: The viability and persistence of a polyphagous, non-native insect