Moderate ethanol consumption interacts with Aβ to exacerbate Alzheimer's-like pathological, behavioral, and metabolic deficits in mice
Novel and highly distributed classes of hindbrain neuronal activity contribute to sensory processing and motor control in the Xenopus laevis tadpole.
Weakly deleterious natural genetic variation greatly amplifies probability of resistance in multiplexed gene drive systems Transcription disrupts DNA-scaffolded bacteriophage repressor complexes Predicting microbiome compositions from species assemblages through deep learning. Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Modular evolution of secretion systems and virulence plasmids in a bacterial species complex Serological fingerprints link antiviral activity of therapeutic antibodies to affinity and concentration Use of lignocellulosic residue from second-generation ethanol production to enhance methane production through co-digestion A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD Arabidopsis AtPME2 has a pH-dependent processivity and control cell wall mechanical properties A Hierarchy of Biomolecular Proportional-Integral-Derivative Feedback Controllers for Robust Perfect Adaptation and Dynamic Performance Modulation of P2X4 pore closure by magnesium,potassium, and ATP A cell-based screen identifies HDAC inhibitors as activators of RIG-I signaling TeamTree analysis: a new approach to evaluate scientific production Somatic uniparental disomy mitigates the most damaging EFL1 allele combination in Shwachman-Diamond syndrome Sablefish (Anoplopoma fimbria Pallas, 1814) plasma biochemistry and hematology reference intervals including blood cell morphology Oct1 recruits the histone lysine demethylase Utx to promote lineage specification Climate warming changes synchrony of plants and pollinators Drug development of an affinity enhanced, broadly neutralizing heavy chain-only antibody that restricts SARS-CoV-2 in rodents Generalizing predictions to unseen sequencing profiles via deep generative models Fatal neuroinvasion and SARS-CoV-2 tropism in K18-hACE2 mice is partially independent on hACE2 expression A General Biphasic-Bodyweight Model for Scaling Basal Metabolic Rate, Glomerular Filtration Rate and Drug Clearance from Birth to Adulthood Growth of the Radiotrophic Fungus Cladosporium sphaerospermum aboard the International SpaceStation and Effects of Ionizing Radiation Sensing their plasma membrane curvature allows migrating cells to circumvent obstacles Thermal modulation of Zebrafish exploratory statistics reveals constraints on individual behavioral variability