Cell type identification in spatial transcriptomics data can be improved by leveraging cell-type-informative paired tissue images using a Bayesian probabilistic model.
Building a Knowledge Graph to Enable Precision Medicine
A nuclear import pathway exploited by pathogenic noncoding RNAs Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing CRCM5484: A BET- BDII Selective Compound With Differential Anti-Leukemic Drug Modulation Molecular Dynamics Simulations of Phytopthora sojae Avirulence Factor 5, PsAvh5, Define Membrane Binding, Inositolphosphate-3'-phosphate Interactions and Protein Mechanics Small extracellular vesicles from young mice prevent frailty, improve healthspan and decrease epigenetic age in old mice. Deficits in seizure threshold and other behaviors in adult mice without gross neuroanatomic injury after late gestation transient prenatal hypoxia Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir (PF-07321332) A General Biphasic-Bodyweight Model for Scaling Basal Metabolic Rate, Glomerular Filtration Rate and Drug Clearance from Birth to Adulthood High quality mapping of chromatin at or near the nuclear lamina for small numbers of cells Extracellular Matrix Hydrogels Promote Expression of Muscle-Tendon Junction Proteins Herbivore life histories are altered by drought stress in their hosts plants Morphological aspects of opossum (Didelphis aurita) pancreas during intramarsupial development Synthetic Antigen Presenting cells reveal the diversity and functional specialisation of extracellular vesicles composing the fourth signal of T cell immunological synapses. Rho Kinase regulates neutrophil NET formation that is involved in UVB-induced skin inflammation Niche differences, not fitness differences, explain coexistence across ecological groups Cold stress upregulates the expression of heat shock and Frost genes, but the evolution of cold stress resistance is apparently not mediated through either heat shock or Frost genes in the cold stress selected populations of Drosophila melanogaster STING mediates immune responses in the closest living relatives of animals Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Express Arm Responses Appear Bilaterally on Upper-limb Muscles in An Arm Choice Reaching Task Design, Mutate, Screen: High-throughput creation of genetic clocks with different period-amplitude characteristics A multi-dimensional integrative scoring framework for predicting functional variants in the human genome The isoforms of pyruvate kinase act as nutrient sensors for the β-cell KATP channel High school science fair: Experiences of two groups of undergraduate bioscience students