Ultrafast Simulation of Large-Scale Neocortical Microcircuitry with Biophysically Realistic Neurons
The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects
A Eukaryotic Circuit for Secretion-coupled Cellular Autonomy Ultrahigh-Throughput Ambient MS: Direct Analysis at 22 Samples per Second by Infrared Matrix-Assisted Desorption Electrospray Ionization Mass Spectrometry bulkAnalyseR: An accessible, interactive pipeline for analysing and sharing bulk multi-modal sequencing data Game of theories: an agent-based model of how variation in contest cost-benefits determines the evolution of contest resolution rules Fatal neuroinvasion and SARS-CoV-2 tropism in K18-hACE2 mice is partially independent on hACE2 expression Conserved organ-specific microbial assemblages in different populations of a terrestrial crab Gene structure-based homology search identifies highly divergent putative effector gene family Mouse lemur, a new primate model to investigate cardiac pacemaker activity. Coordination of genome replication and anaphase entry by rDNA copy number in S. cerevisiae Macroscopic control of synchronous electrical signaling with chemically-excited gene expression Epidural Electrical Stimulation of the Cervical Dorsal Roots Restores Voluntary Upper Limb Control In Paralyzed Monkeys PRSS2 stimulates tumor growth by remodeling the TME via repression of Tsp1 CCL28 modulates neutrophil responses during infection with mucosal pathogens Late-acting self-incompatible system, preferential allogamy and delayed selfing in the heteromorphic invasive populations of Ludwigia grandiflora subsp. hexapetala Absence of cardiolipin from the outer-leaflet of a mitochondrial inner-membrane mimic restricts Opa1-mediated fusion A novel 5 prime DNA binding site in RFC facilitates PCNA loading for gap DNA repair A bacterial effector counteracts host autophagy by promoting degradation of an autophagy component Admp regulates tail bending by controlling ventral epidermal cell polarity via phosphorylated myosin translocation. Low dose rate γ-irradiation protects Drosophila melanogaster chromosomes from double strand breaks and telomere fusions by modulating the expression of the esi-RNA biogenesis factor Loquacious. Compendium of secondary metabolite biosynthetic diversity encoded in bacterial genomes SARS-CoV-2 B.1.617.2 Delta variant replication, sensitivity to neutralising antibodies and vaccine breakthrough Secretory cells are the primary source of pIgR in small airways Affordable Caenorhabditis elegans tracking system for classroom use Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition