Characterizing and explaining impact of disease-associated mutations in proteins without known structures or structural homologues
PrISM: precision for integrative structural models
Multi-omic analysis of the Arabidopsis clock activator mutant rve 4 6 8 reveals connections to carbohydrate metabolism and proteasome regulation Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Glucose inhibits haemostasis and accelerates diet-induced hyperlipidaemia in zebrafish larvae Naturally enhanced neutralizing breadth to SARS-CoV-2 after one year No impact of biocontrol agent's predation cues on development time or size of surviving Aedes albopictus under optimal nutritional availability Macroscopic control of synchronous electrical signaling with chemically-excited gene expression A Substrate-triggered μ-Peroxodiiron(III) Intermediate in the 4-Chloro-L-Lysine-Fragmenting Heme-Oxygenase-like Diiron Oxidase (HDO) BesC: Substrate Dissociation from, and C4 Targeting by, the Intermediate Mouse lemur, a new primate model to investigate cardiac pacemaker activity. High-throughput analysis of single human cells reveals the complex nature of DNA replication timing control Activation of the type 3 secretion system of enteropathogenic E. coli leads to remodeling of its membrane composition Co-option of immune effectors by the hormonal signalling system triggering metamorphosis in Drosophila melanogaster Shedding Light on the Circadian Clock of the Threespine Stickleback Propionate ameliorates diabetes-induced neurological dysfunction through regulating the PI3K/Akt/eNOS signaling pathway Force-dependent remodeling of cytoplasmic ZO-1 condensates contributes to cell-cell adhesion Seed banks alter the molecular evolutionary dynamics of Bacillus subtilis The voltage and spiking responses of subthreshold resonant neurons to structured and fluctuating inputs: persistence and loss of resonance and variability A Novel Paradigm for Deep Reinforcement Learning of Biomimetic Systems The 55K SNP-Based Exploration of QTL for Spikelet Number Per Spike in a Tetraploid Wheat (Triticum turgidum L.) Population: Chinese Landrace Ailanmai X Wild Emmer Morphology of immatures of the thelytokous ant, Monomorium triviale Wheeler (Formicidae: Myrmicinae: Solenopsidini) with descriptions of the extraordinary last-instar queen larvae Molecular Dynamics Simulations of Phytopthora sojae Avirulence Factor 5, PsAvh5, Define Membrane Binding, Inositolphosphate-3'-phosphate Interactions and Protein Mechanics YfiB: An Outer Membrane Protein Involved in the Virulence of Shigella flexneri Spontaneous differentiation leads to emergence of hybrid cell states relate to poor prognosis in oral cancer If Research is Not the Evidence, What is it? The Lack of Research Citations in Health Vlogs Polycystin promotes renal fibrosis through EZH2