Building a Knowledge Graph to Enable Precision Medicine
Structural effects driven by rare point mutations in amylin hormone, the type II diabetes-associated peptide
Bidirectional Control of Parathyroid Hormone and Bone Mass by Subfornical Organ ZIKV disrupts placental ultrastructure and drug transporter expression in mice Modeling Adsorption, Conformation, and Orientation of the Fis1 Tail Anchor at the Mitochondrial Outer Membrane Developing High-Affinity Decoy Receptor Optimized for Multiple Myeloma and Diffuse Large B Cell Lymphoma Treatment ATP-binding cassette protein ABCF1 couples gene transcription with maintenance of genome integrity in embryonic stem cells Amoxicillin-resistant Streptococcus pneumoniae can be resensitized by targeting the mevalonate pathway as indicated by sCRilecs-seq Lyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2 A novel method for producing functionalized vesicles that efficiently deliver oligonucleotides in vitro in cancer cells and in vivo in mice Balancing sensitivity and specificity in preclinical research Substantial genetic mixing among sexual and androgenetic lineages within the clam genus Corbicula Quantifying the Morphology and Mechanisms of Cancer Progression in 3D in-vitro environments: Integrating Experiments and Multiscale Models Non-specific effects of a CINNAMATE-4-HYDROXYLASE inhibitor on auxin homeostasis Ultrahigh-Throughput Ambient MS: Direct Analysis at 22 Samples per Second by Infrared Matrix-Assisted Desorption Electrospray Ionization Mass Spectrometry Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects Frequency modulated timer regulates mammalian hibernation Heterogeneous recruitment abilities to RNA polymerases generate nonlinear scaling of gene expression level with cell volume A new method for the sampling and preservation of placental specimens in low-resource settings for the identification of P. falciparum and analysis of nucleic acids Newly developed ad hoc molecular assays show how eDNA can witness and anticipate the monk seal recolonization of central Mediterranean Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Expansion of mutation-driven haematopoietic clones is associated with insulin resistance and low HDL-cholesterol in individuals with obesity Embracing curiosity eliminates the exploration-exploitation dilemma Engineered bacteria detect tumor DNA Comparative analysis of cattle breeds as satellite cell donors for cultured beef Selection towards lighter seeds in Danish grasslands over an eight-year period