Synergy of chemotherapy and macrophage depletion leads to B cell-mediated T cell memory activation and durable triple negative breast cancer regression
Loss of Nuclear DNA Ligase III Reverts PARP Inhibitor Resistance in BRCA1/53BP1 Double-deficient Cells by Exposing ssDNA Gaps
Polycystins are upregulated in fibrotic kidneys and promote renal fibrosis Yersinia remodels epigenetic histone modifications in human macrophages To knot or not to knot: Multiple conformations of the SARS-CoV-2 frameshifting RNA element Surface-associated antigen induces B-cell permeabilization and lysosome exocytosis facilitating antigen uptake and presentation to T-cells Transmembrane helices are an overlooked and evolutionarily conserved source of major histocompatibility complex class I and II epitopes Allopatric divergence of cooperators confers cheating resistance and limits the effects of a defector mutation Adolescent Alcohol Binge-Drinking induces delayed appearance of behavioral defects in mice Similarities Between Bacterial GAD and Human GAD65: Implications in Gut Mediated Autoimmune Type 1 Diabetes Allosteric activation of SARS-CoV-2 RdRp by remdesivir triphosphate and other phosphorylated nucleotides Mendelian Randomization for causal inference accounting for pleiotropy and sample structure using genome-wide summary statistics A chemical screen based on an interruption of zebrafish gastrulation identifies the HTR2C inhibitor Pizotifen as a suppressor of EMT-mediated metastasis The joint evolution of animal movement and competition strategies "Adopt a Microorganism" methodology enhances the discourse richness of high school students in both hybrid learning and remote education Single-value scores of memory-related fMRI activity reflect dissociable neuropsychological and anatomical signatures of neurocognitive aging Herbivore life histories are altered by drought stress in their hosts plants METHYLOME DYNAMICS UPON PROTEASOME INHIBITION BY THE PSEUDOMONAS VIRULENCE FACTOR SYRINGOLIN A Using machine learning to design adeno-associated virus capsids with high likelihood of viral assembly Bulk-assembly of monodisperse coacervates and giant unilamellar vesicles with programmable hierarchical complexity C. elegans PEZO-1 is a Mechanosensitive Ion Channel Involved in Food Sensation BlenderPhotonics - an integrated open-source software environment for 3-D meshing and photon simulations in complex tissues Proton-driven alternating access in a spinster transporter, an emerging family of broad-specificity efflux pumps Modeling predicts differences in CAR T cell signaling due to biological variability Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition The compound of baicalein, wogonin, and oroxylin-A inhibits EMT in A549 cell line via PI3K/AKT-TWIST1-glycolysis pathway