Improved AlphaFold modeling with implicit experimental information
Hidden dynamics of proteasome autoregulation discovered by cryo-EM data-driven deep learning
Modulation of P2X4 pore closure by magnesium,potassium, and ATP Adolescent development of multiscale structural wiring and functional interactions in the human connectome Improving human coronavirus OC43 (HCoV-OC43) research results comparability in studies using HCoV-OC43 as a surrogate for SARS-CoV-2 Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Catchet-MS identifies IKZF1-targeting Thalidomide analogues as novel HIV-1 latency reversal agents Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: the Multi-Targeting Drug DREAM Challenge Late-life fitness gains explain the absence of a selection shadow in ants Epidural Electrical Stimulation of the Cervical Dorsal Roots Restores Voluntary Upper Limb Control In Paralyzed Monkeys Analysis of science journalism reveals gender and regional disparities in coverage Measuring transcription factor binding and gene expression using barcoded self-reporting transposon calling cards and transcriptomes A novel adhesive complex at the base of intestinal microvilli A multivariate view of cognitive performance reveals positive correlation in the Trinidadian Guppy (Poecilia reticulata) Minimizing spectral overlap in multicolor flow cytometry experiments Rapid global phaseout of animal agriculture has the potential to stabilize greenhouse gas levels for 30 years and offset 68 percent of CO2 emissions this century Define protein variant functions with high-complexity mutagenesis libraries and enhanced mutation detection software ASMv1.0 Regulation of ammonium acquisition and use in Oryza longistaminata ramets under nitrogen source heterogeneity Reconstitution of minimal motility system based on Spiroplasma swimming by expressing two bacterial actins in synthetic minimal bacterium Inhibition of BCMA signaling alters protein translation and Multiple Myeloma growth Microbial colonization of tannin-rich tropical plants: interplay between degradability, methane production and tannin disappearance in the rumen Neuroinvasion and neurotropism by SARS-CoV-2 variants in the K18-hACE2 mouse Hnf1b-CreER causes efficient recombination of a Rosa26-RFP reporter in duct and islet δ cells Spontaneous Transmembrane Pore Formation by Short-chain Synthetic Peptide Multivariate Genomewide Association Analysis by Iterative Hard Thresholding Blocking antibodies against integrin-a3, integrin-aM, and integrin-aMb2 de-differentiate myofibroblasts and reverse lung and kidney fibroses in a mouse model