Swine H1N1 influenza virus variants with enhanced polymerase activity and HA stability promote airborne transmission in ferrets
Structure-guided synthesis of FK506 and FK520 analogs with increased selectivity exhibit in vivo therapeutic efficacy against Cryptococcus
A partially nested cortical hierarchy of neural states underlies event segmentation in the human brain Establishing combination PAC-1 and TRAIL regimens for treating ovarian cancer based on patient-specific pharmacokinetic profiles using in silico clinical trials Dysfunction of an energy sensor NFE2L1 triggers uncontrollable AMPK signal and glucose metabolism reprogramming Evidence for a hydrogen sulfide-sensing E3 ligase in yeast Improved prediction of protein-protein interactions using AlphaFold2 Regulation of the PKD2 channel function by TACAN Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition GPI-anchored FGF directs cytoneme-mediated bidirectional signaling to self-regulate tissue-specific dispersion Pathways of savannization in a mesic African savanna-forest mosaic Microorganisms Characterization in Anaerobic Solventogenic Processing of Volatile Fatty Acids Speciation dynamics and extent of parallel evolution along a lake-stream environmental contrast in African cichlid fishes Failure to account for behavioral variability significantly compromises accuracy in indirect population monitoring An exon-intron split framework to prioritize miRNA-driven post-transcriptional regulatory signals and its application to study energy homeostasis in pigs Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies Frequency modulated timer regulates mammalian hibernation Hematopoietic differentiation is characterized by a transient peak of entropy at a single cell level. Immunogenicity of SARS-CoV-2 trimetric spike protein associated to Poly(I:C) plus Alum Proximity labeling reveals spatial regulation of the anaphase-promoting complex/cyclosome by a microtubule adaptor Analysis of science journalism reveals gender and regional disparities in coverage Leaf Aqueous Extract of Manilkara hexandra influenced Glucose Metabolism in fish: An observation with Labeo rohita Fingerlings as model organism Macroscopic control of synchronous electrical signaling with chemically-excited gene expression High expression of VRT2 increases the number of rudimentary basal spikelets in wheat Rho Kinase regulates neutrophil NET formation that is involved in UVB-induced skin inflammation Betacoronavirus binding dynamics relevant to the functional evolution of the highly transmissible SARS-CoV-2 variant N501Y