Design of anti-SARS-CoV-2 molecules from hydroxychloroquine (HCQ)for better binding SARS-CoV-2 N protein
Elucidating Microscopic Events Driven by GTP Hydrolysis Reaction in Ras-GAP System with Semi-reactive Molecular Dynamics Simulation: Alternative Role of Phosphate Binding Loop as Mechanical Energy Storage
Phylogenetic and population structure analyses uncover pervasive misclassification and help assessing the biosafety of Pseudomonas alloputida for biotechnological applications Mechanistic basis for understanding the dual activities of the bifunctional Azotobacter vinelandii mannuronan C-5 epimerase and alginate lyase AlgE7 The snoGloBe interaction predictor reveals a broad spectrum of C/D snoRNA RNA targets Maternal microbiota Bifidobacterium promotes placental morphogenesis, nutrient transport and fetal growth in mice Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Social behavioral profiling by unsupervised deep learning reveals a stimulative effect of dopamine D3 agonists on zebrafish sociality Sensing Local Field Potentials with a Directional and Scalable Depth Array: the DISC array IRGM/Irgm1 Aggravates Progression of Atherosclerosis by Inducing Macrophage Apoptosis through the MAPK Signaling Pathway LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants Intramolecular carbon isotope signals reflect metabolite allocation in plants Perceiving and remembering speech depend on multifractal nonlinearity in movements producing and exploring speech An alignment free approach confirms semantic properties of species proteomes A natural mutator allele shapes mutation spectrum variation in mice A chromosome-level assembly of the "Cascade" hop (Humulus lupulus) genome uncovers signatures of molecular evolution and improves time of divergence estimates for the Cannabaceae family Neurological mechanism of sensory deficits after developmental exposure to non-dioxin-like polychlorinated biphenyls (PCBs) in zebrafish larvae Evolution of bacterial persistence to antibiotics during a 50,000-generation experiment in an antibiotic-free environment Effects of substrate on shrimp growth, water quality and bacterial community in the biofloc system nursing Penaeus vannamei postlarvae Synthetic periphyton as a model system to understand species dynamics in complex microbial freshwater communities The integrity and assay performance of tissue mitochondrial DNA is considerably affected by choice of isolation method Beyond tracking climate: niche shifts during native range expansion and their implications for novel invasions Tracheal tube fusion in Drosophila involves release of exosomes from multivesicular bodies Quantifying ERK-activity in response to inhibition of the BRAFV600E-MEK-ERK cascade using mathematical modelling TCAB1 prevents nucleolar accumulation of the telomerase RNA to promote telomerase assembly Naming Human Diseases: Ethical Principles of Curating Exclusive Substitute for Inopportune Nosology