Balancing sensitivity and specificity in preclinical research
Preprints in motion: tracking changes between preprint posting and journal publication during a pandemic
Phylogenomic discordance suggests polytomies along the backbone of the large genus Solanum Molecular basis for gating of cardiac ryanodine receptor: underlying mechanisms for gain- and loss-of function mutations Essential Regression - a generalizable framework for inferring causal latent factors from multi-omic human datasets Changes to the mtDNA copy number during yeast culture growth Notch signaling via Hey1 and Id2b regulates Muller glia's regenerative response to retinal injury Reconstitution of minimal motility system based on Spiroplasma swimming by expressing two bacterial actins in synthetic minimal bacterium The influence of saccades on insect flight control A revised view on the evolution of glutamine synthetase isoenzymes in plants Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition The adenoviral E1B-55k protein present in HEK293 cells mediates abnormal accumulation of key WNT signaling proteins in large cytoplasmic aggregates. Large protein complex interfaces have evolved to promote cotranslational assembly Sarcoplasmic reticulum calcium handling in young DBA/2J vs C57BL/10 mdx models of Duchenne muscular dystrophy Extracellular Vesicle (EV) Mitochondria and EV/HSP27 Mixtures Protect the Ischemic Brain Endothelium Evolution of thermal physiology alters the projected range of threespine stickleback under climate change An mRNA SARS-CoV-2 vaccine employing Charge-Altering Releasable Transporters with a TLR-9 agonist induces neutralizing antibodies and T cell memory First detection of herpesvirus and prevalence of mycoplasma infection in free-ranging Hermann s tortoises (Testudo hermanni), and in potential pet vectors Trypanosomal variant surface glycoprotein expression in human African trypanosomiasis patients Tackling polypharmacology of kinase inhibitors and selecting chemical kinase probes by transcription factor activity profiling. Effect of a low concentration in chloride, sodium and potassium on oocyte maturation, oocyte hydration, ovulation and egg quality in rainbow trout. Foraging with friends, moving with anyone: effects of the social environment on movement-integrated habitat selection Top-down generation of low-precision representations improves the perception and imagination of fine-scale visual information Evolution of myoglobin in avian lineages: positive selection for aggregation resistance in penguins and high purifying selection in galliforms Survival Genie, a web platform for survival analysis across pediatric and adult cancers. Parallel Characterization of cis-Regulatory Elements for Multiple Genes Using CRISPRpath