Curation, inference, and assessment of a globally reconstructed gene regulatory network for Streptomyces coelicolor
Multifunctional RNA-binding proteins influence mRNA abundance and translational efficiency of distinct sets of target genes
Dendritic inhibition by Shh signaling-dependent stellate cell pool is critical for motor learning Text has been revised, image definition has been revised. Sequence features of retrotransposons allow for epigenetic variability Targeted biallelic integration of an inducible Caspase 9 suicide gene for safer cellular therapies prevents development of drug-resistant escapees in human iPSCs Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Communities of tropical soil fungi differ between burned and unburned forest, with corresponding changes in plant community composition, litter and soil chemistry Batch experiments demonstrating a two-stage bacterial process coupling methanotrophic and heterotrophic bacteria for 1-alkene production from methane Conserved organ-specific microbial assemblages in different populations of a terrestrial crab A memetic algorithm enables efficient local and global all-atom protein-protein docking with backbone and sidechain flexibility Shedding Light on the Circadian Clock of the Threespine Stickleback A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection Toxicity Profile of Artesunate in Rats and Dogs Tunable Cellular Localization and Extensive Cytoskeleton-Interplay of Reflectins Evidence of an additional wild contributor, Malus orientalis Uglitzk., to the genome of cultivated apple varieties in the Caucasus and Iran Highly efficient synthetic CRISPR RNA/Cas9-based mutagenesis for rapid cardiovascular phenotypic screening in F0 zebrafish Hydrophobic mismatch is a key factor in protein transport on the Tat pathway Intermittent KHz-frequency electrical stimulation selectively engages small unmyelinated vagal afferents Design, Mutate, Screen: High-throughput creation of genetic clocks with different period-amplitude characteristics Naming Human Diseases: Ethical Principles of Curating Exclusive Substitute for Inopportune Nosology Enhancing CDK4/6 inhibitor therapy for medulloblastoma using nanoparticle delivery and scRNA-seq-guided combination with sapanisertib Genome-wide analysis of the non-coding RNA synthetic genetic network reveals extensive plasticity and unique phenotypes in yeast Sarcoplasmic reticulum calcium handling in young DBA/2J vs C57BL/10 mdx models of Duchenne muscular dystrophy Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids Interplay between receptor binding, immune escape and protein stability determines the natural selection of SARS-CoV-2 variants