Comparative toxicogenomics of glyphosate and Roundup herbicides by mammalian stem cell-based genotoxicity assays and molecular profiling in Sprague-Dawley rats
Tackling polypharmacology of kinase inhibitors and selecting chemical kinase probes by transcription factor activity profiling.
Skeletal muscle methylome and transcriptome integration reveals profound sex differences related to muscle function and substrate metabolism Cryptic fertility costs of viral infection in a model social insect Feed efficiency of lactating Holstein cows was not as repeatable across diets as within diet over subsequent lactation stages Reconstitution of minimal motility system based on Spiroplasma swimming by expressing two bacterial actins in synthetic minimal bacterium Mechanisms of damage prevention, signalling, and repair impact disease tolerance Bespoke data augmentation and network construction enable developmental morphological classification on limited microscopy datasets CRCM5484: A BET- BDII Selective Compound With Differential Anti-Leukemic Drug Modulation Small extracellular vesicles from young mice prevent frailty, improve healthspan and decrease epigenetic age in old mice. Optical regulation of endogenous RhoA reveals selection of cellular responses by signal amplitude Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Comparison of hybrid learning and remote education in the implementation of the 'Adopt a Microorganism' methodology The Inflammatory Role of Milk Fat Globule Epidermal Growth Factor VIII in Angiotensin II Induced Arterial Remodeling HP1 oligomerization compensates for low-affinity H3K9me recognition and provides a tunable mechanism for heterochromatin-specific localization Teosinte mexicana introgression modulates phosphatidylcholine levels and maize flowering time Large-scale analysis of SARS-CoV-2 synonymous mutations reveals the adaptation to the human codon usage during the virus evolution Extracting spatial networks from capture-recapture data reveal structured habitat use within a marine mammal's spatial range Oxytocinergic modulation of stress-associated amygdala-hippocampus pathways in humans is mediated by serotonergic mechanisms A rationalized definition of general tumor suppressor microRNAs excludes miR-34a Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication Bacterial CRISPR-Cas Abundance Increases Precipitously at Around 45°C: Linking Antivirus Immunity to Grazing Risk Mechanisms of A-type lamin targeting to nuclear ruptures are disrupted in LMNA- and BANF1-associated progerias Different contribution of the monkey prefrontal and premotor dorsal cortex in decision making during a transitive inference task Molecular basis for gating of cardiac ryanodine receptor: underlying mechanisms for gain- and loss-of function mutations Commercial porcine gastric mucin contributes to variation in production of small molecule virulence factors by Pseudomonas aeruginosa when cultured in different formulations of artificial sputum medium