CHRM1 is a Druggable Melanoma Target Whose Endogenous Activity is Determined by Inherited Genetic Variation in DOPA Production
Sex biases in cancer and autoimmune disease incidence are strongly positively correlated with mitochondrial gene expression across human tissues
Biophysical characterization of the oligomeric states of recombinant Immunoglobulins type-M and their C1q binding kinetics by Biolayer Interferometry Trade-offs in biosensor optimization for dynamic pathway engineering Spatial proteomics reveals subcellular reorganization in human keratinocytes exposed to UVA light Population bottlenecks constrain host microbiome diversity and genetic variation impeding fitness A phenomics approach for in vitro antiviral drug discovery An hidden Markov model to estimate homozygous-by-descent probabilities associated with nested layers of ancestors E156G and Arg158, Phe-157/del mutation in NTD of spike protein in B.1.617.2 lineage of SARS-CoV-2 leads to immune evasion through antibody escape Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Anti- SARS-CoV-2 Receptor Binding Domain Antibody Evolution after mRNA Vaccination Glucose inhibits haemostasis and accelerates diet-induced hyperlipidaemia in zebrafish larvae Sleep loss disrupts the neural signature of successful learning Tracing back variations in archaeal cell division to protein domain architectures De novo chromosome-length assembly of the mule deer (Odocoileus hemionus) genome Transcriptomic analysis of temporal shifts in berry development between two grapevine cultivars of the Pinot family reveals potential genes controlling ripening time Estimating the fundamental niche: accounting for the uneven availability of existing climates Risk modelling of single cell populations revealed the heterogeneity of immune infiltration in hepatocellular carcinoma Outer hair cell electro-mechanical power conversion Kaposi's sarcoma-associated herpesvirus (KSHV) utilizes the NDP52/CALCOCO2 selective autophagy receptor to disassemble processing bodies First evidence of in vitro cytotoxic effects of marine microlitter on Merluccius merluccius and Mullus barbatus, two Mediterranean commercial fish species An NLR Integrated Domain toolkit to identify plant pathogen effector targets Development of antibiotic resistance reveals diverse evolutionary pathways to face the complex and dynamic environment of a long-term treated patient A Proteome-Wide Map of Chaperone-Assisted Protein Refolding in the Cytosol A tool for assessing alignment of biomedical data repositories with open, FAIR, citation and trustworthy principles Juvenile Gouldian Finches (Erythrura gouldiae) form sibling sub-groups during social integration