Skeletal muscle methylome and transcriptome integration reveals profound sex differences related to muscle function and substrate metabolism
Host Variation in Type I Interferon Signaling Genes (MX1), CCR5{triangleup}32, and MHC Class I Alleles in Treated HIV+ Non-Controllers Predict Viral Reservoir Size
Age-associated B cells are long-lasting effectors that restrain reactivation of latent γHV68 Two levels of selection of rhythmicity in gene expression: energy saving for rhythmic proteins and noise optimization for rhythmic transcripts Material-mediated histogenesis using mechano-chemically microstructured cell niches Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies SARS-CoV-2 variants show a gradual declining pathogenicity and pro-inflammatory cytokine spur, an increasing antigenic and anti-inflammatory cytokine induction, and rising structural protein instability DNA Strand Breaks and Gaps Direct Retroviral Integration A natural mutator allele shapes mutation spectrum variation in mice The evolution of stomatal traits along the trajectory towards C4 photosynthesis The Temporal Pattern of Synaptic Activation Determines the Longevity of Structural Plasticity at Single Dendritic Spines Feedforward regulatory logic underlies robustness of the specification-to-differentiation transition and fidelity of terminal cell fate during C. elegans endoderm development Common coupling map advances GPCR-G protein selectivity Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition HSP90 modulates T2R bitter taste receptor nitric oxide production and innate immune responses in human airway epithelial cells and macrophages Define protein variant functions with high-complexity mutagenesis libraries and enhanced mutation detection software ASMv1.0 PLB-985 neutrophil-like cells as a model to study Aspergillus fumigatus pathogenesis P2X2 receptor subunit interfaces are missense variant hotspots where mutations tend to increase apparent ATP affinity Naming of human diseases on the wrong side of history First evidence of in vitro cytotoxic effects of marine microlitter on Merluccius merluccius and Mullus barbatus, two Mediterranean commercial fish species A Hierarchy of Biomolecular Proportional-Integral-Derivative Feedback Controllers for Robust Perfect Adaptation and Dynamic Performance The Hippocampus uses cryptographic principles rather than plasticity to enable animals to secretly cache and retrieve their food Single-molecule imaging of cytoplasmic dynein in cellulo reveals the mechanism of motor activation and cargo capture Maf/ham1-like pyrophosphatases of non-canonical nucleotides are host-specific partners of viral RNA-dependent RNA polymerases An epigenetic memory of inflammation controls context-dependent lineage plasticity in the pancreas Rapid global phaseout of animal agriculture has the potential to stabilize greenhouse gas levels for 30 years and offset 68 percent of CO2 emissions