BatchDTA: Implicit batch alignment enhances deep learning-based drug-target affinity estimation
Integrated quality control of allele-specific copy numbers, mutations and tumour purity from cancer whole genome sequencing assays
Non-Newtonian Blood Rheology Impacts Left Atrial Stasis in Patient-Specific Simulations Experimental characterization of in silico red-shift predicted iLOVL470T/Q489K and iLOVV392K/F410V/A426S mutants Bespoke data augmentation and network construction enable developmental morphological classification on limited microscopy datasets Rapid evolution of seed dormancy during sunflower de-domestication Beneficial effects of novel strains of Aureobasidium pullulans produced 1,3-1,6 β-glucans on non-esterified fatty acid levels in diabetic KKAy mice Inhibitory proteins block substrate access to the membrane-embedded active site of Bacillus subtilis intramembrane metalloprotease SpoIVFB First evidence of in vitro cytotoxic effects of marine microlitter on Merluccius merluccius and Mullus barbatus, two Mediterranean commercial fish species Liberation from fibrogenesis or tumorigenesis via cellular senescence by a novel small molecule Poly ADP-ribosylation of SET8 leads to aberrant H4K20 methylation domains in mammalian cells Development and Characterization of PAR-Trackers: New Tools for Detecting Poly(ADP-ribose) In Vitro and In Vivo TCF11 Has a Potent Tumor-Repressing Effect than Its Prototypic Nrf1α by Definition of both Similar yet Different Regulatory Profiles, with a Striking Disparity from Nrf2 Phylogenetic analysis of molecular pathways in Tregs Suppressor Function A protease-activatable luminescent biosensor andreporter cell line for authentic SARS-CoV-2 infection Inflammasome activation in infected macrophages drives COVID-19 pathology Eye movements elevate crowding in idiopathic infantile nystagmus syndrome Allopurinol Blocks The Formation And Progression Of Aortic Aneurysm In A Mouse Model Of Marfan Syndrome A parametric logistic equation with light flux and medium concentration for cultivation planning of microalgae A tool for assessing alignment of biomedical data repositories with open, FAIR, citation and trustworthy principles Revisiting regulatory decoherence and phenotypic integration: accounting for temporal bias in co-expression analyses Pathways of savannization in a mesic African savanna-forest mosaic following an extreme fire Outer hair cell electro-mechanical power conversion Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition Cell type-specific inference of differential expression in spatial transcriptomics Flexible control of Pavlovian-instrumental transfer based on expected reward value