Navigating the amino acid sequence space between functional proteins using a deep learning framework
Profiles of expressed mutations in single cells reveal subclonal expansion patterns and therapeutic impact of intratumor heterogeneity
Single amino-acid mutation in a Drosophila melanogaster ribosomal protein: an insight in uL11 transcriptional activity Game of theories: an agent-based model of how variation in contest cost-benefits determines the evolution of contest resolution rules The physics of liquid-to-solid transitions in multi-domain protein condensates The functional role of episodic memory in spatial learning SkewDB: A comprehensive database of GC and 10 other skews for over 28,000 chromosomes and plasmids Testing for phylogenetic signal in single-cell RNA-seq data First evidence of in vitro cytotoxic effects of marine microlitter on Merluccius merluccius and Mullus barbatus, two Mediterranean commercial fish species Naming of human diseases on the wrong side of history Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation High-pressure sprayed siRNAs trigger influence the efficiency but not the profile of transitive silencing A high throughput lipidomics method using scheduled multiple reaction monitoring Medium-throughput zebrafish optogenetic platform identifies deficits in subsequent neural activity following brief early exposure to cannabidiol and Δ-9-tetrahydrocannabinol Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 Microorganisms Characterization in Anaerobic Solventogenic Processing of Volatile Fatty Acids Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition The limits of evolutionary convergence in sympatry: reproductive interference and historical constraints leading to local diversity in warning traits Wnt target enhancer regulation by a CDX/TCF transcription factor collective and a novel DNA motif Linking plankton size spectra and community composition to carbon export and its efficiency Reliance of neuronal gene expression on cohesin scales with chromatin loop length Pak1 and PP2A antagonize aPKC function to support cortical tension induced by the Crumbs-Yurt complex Glucose inhibits haemostasis and accelerates diet-induced hyperlipidaemia in zebrafish larvae High performance single-cell gene regulatory network inference atscale: The Inferelator 3.0 Non-targeted multimodal metabolomics and lipidomics data from ovine rumen fluid fractions A Hierarchy of Biomolecular Proportional-Integral-Derivative Feedback Controllers for Robust Perfect Adaptation and Dynamic Performance