Cellular Fitness Phenotypes of Cancer Target Genes from Oncobiology to Cancer Therapeutics
Recurrent exon-deleting activating mutations in AHR act as drivers of urinary tract cancer
Mapping densely packed GPIIb/IIIa receptors in murine blood platelets with expansion microscopy An AI-guided signature reveals the nature of the shared proximal pathways of host immune response in MIS-C and Kawasaki disease Naming of human diseases on the wrong side of history Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes with Chemical Crosslinking Mass Spectrometry First detection of herpesvirus and prevalence of mycoplasma infection in free-ranging Hermann s tortoises (Testudo hermanni), and in potential pet vectors Pathogenic, but not non-pathogenic, Rickettsia evade inflammasome-dependent IL-1 responses to establish an intracytosolic replication niche. Data-Driven Network Models for Genetic Circuits From Time-Series Data with Incomplete Measurements The Tabula Sapiens: a multiple organ single cell transcriptomic atlas of humans Long term analysis of social structure: evidence of age-based consistent associations in male Alpine ibex Production and characterization of virus-free, CRISPR-CAR T cells capable of inducing solid tumor regression Arabidopsis AtPME2 has a pH-dependent processivity and control cell wall mechanical properties Inter-tissue convergence of gene expression during ageing suggests age-related loss of tissue and cellular identity Daily torpor reduces the energetic consequences of habitat selection for a widespread bat Exploratory analysis of multiple traits co-adaptations in the population history Genome-wide analysis tracks the emergence of intraspecific polyploids in Phragmites australis EEG Microstate Correlates of Emotion Dynamics and Stimulation Content during Video Watching Diverse stem-chondrichthyan oral structures and evidence for an independently acquired acanthodid dentition A chemical screen based on an interruption of zebrafish gastrulation identifies the HTR2C inhibitor Pizotifen as a suppressor of EMT-mediated metastasis Global Constraints within the Developmental Program of the Drosophila Wing Analysis of Drosophila cardiac hypertrophy by micro-computerized tomography for genetic dissection of heart growth mechanisms An hidden Markov model to estimate homozygous-by-descent probabilities associated with nested layers of ancestors Venomics and antivenomics of Indian spectacled cobra (Naja naja) from the Western Ghats Allopurinol Blocks The Formation And Progression Of Aortic Aneurysm In A Mouse Model Of Marfan Syndrome Kinetoplastid-specific X2-family kinesins interact with a kinesin-like pleckstrin homology domain protein that localizes to the trypanosomal microtubule quartet