This is a list of NFL Draft selections by the Indianapolis Colts, the first draft that the current incarnation of the Colts franchise participated in was 1953, in which they made which gridiron football player, of Oklahoma their first ever selection?
Indianapolis Colts draft history:  The first draft that the current incarnation of the Colts franchise participated in was 1953, in which they made halfback Billy Vessels of Oklahoma their first ever selection. Billy Vessels: Billy Dale Vessels (March 22, 1931 – November 17, 2001) was a gridiron football player.
Billy Dale Vessels