Which contributor to Padrón Real was the first to demonstrate that Columbus' conjecture about Asia's eastern outskirts was wrong?
Padrón Real:  Well known official cartographers and pilots who contributed to and used the map included Amerigo Vespucci, Diogo Ribeiro, Sebastian Cabot, Alonzo de Santa Cruz, and Juan Lopez de Velasco. Amerigo Vespucci: Amerigo Vespucci (] ; March 9, 1454February 22, 1512) was an Italian explorer, financier, navigator and cartographer who first demonstrated that Brazil and the West Indies did not represent Asia's eastern outskirts as initially conjectured from Columbus' voyages, but instead constituted an entirely separate landmass hitherto unknown to people of the Old World.
Amerigo Vespucci