In what Ohio city does the highway which the northern terminus of Pennsylvania Route 75 interchanges with originate?
Pennsylvania Route 75:  The northern terminus is at an interchange with U.S. Route 22 (US 22) and US 322 northeast of Port Royal. U.S. Route 22 in Pennsylvania: U.S. Route 22 (US 22) is an east–west route stretching from Cincinnati, Ohio in the west to Newark, New Jersey in the east.
Cincinnati