In what year did the Highway that connects the major metropolitan areas of St. Louis, Louisville and Lexington in Kentucky, Charleston, West Virginia, and Richmond, Virginia open?
Grayson, Kentucky:  The city has grown in size substantially since the opening of Interstate 64 in 1975 through Carter County. Interstate 64:  I-64 connects the major metropolitan areas of St. Louis, Louisville and Lexington in Kentucky, Charleston, West Virginia, and Richmond, Virginia.
1975