The highway through the Ridge and Valley Province ends at interchange?
Pennsylvania Route 75:  The northern terminus is at an interchange with U.S. Route 22 (US 22) and US 322 northeast of Port Royal. Ridge-and-Valley Appalachians: The Ridge-and-Valley Appalachians, also called the Ridge and Valley Province or the Valley and Ridge Appalachians, are a physiographic province of the larger Appalachian division and are also a belt within the Appalachian Mountains extending from southeastern New York through northwestern New Jersey, westward into Pennsylvania and southward into Maryland, West Virginia, Virginia, Kentucky, Tennessee, Georgia and Alabama.
U.S. Route 22