Isaac McCoy was an advocate of what policy where Native Americans were forcibly removed from their ancestral homelands in the eastern United States to lands west of the Mississippi River?
Isaac McCoy:  He was an advocate of Indian removal from the eastern United States, proposing an Indian state in what is now Kansas, Nebraska, and Oklahoma. Indian removal: Indian removal was a policy of the United States government in the 19th century whereby Native Americans were forcibly removed from their ancestral homelands in the eastern United States to lands west of the Mississippi River, thereafter known as Indian Territory.
Indian removal