What major highway connects to Harrisburg in Pennsylvania and Syracuse in New York and north of the Colonial Park Mall?
Colonial Park Mall:  Located at the NE corner of U.S. Route 22 and Colonial Road in the Colonial Park CDP just east of Interstate 83 and south of Interstate 81, it serves the eastern and northern suburbs of the Harrisburg metropolitan area. Interstate 81:  The major metropolitan areas that I-81 connects to include Harrisburg in Pennsylvania and Syracuse in New York.
Interstate 81