Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.

Example pair: 
Instruction: Summarize the following 2 paragraphs in just 2 sentences. 

Poet, dancer, singer, activist, and scholar Maya Angelou was a world-famous author. She was best known for her unique and pioneering autobiographical writing style.

On April 4, 1928, Marguerite Ann Johnson, known to the world as Maya Angelou, was born in St. Louis, Missouri. Due to her parents’ tumultuous marriage and subsequent divorce, Angelou went to live with her paternal grandmother in Stamps, Arkansas at an early age. Her older brother, Bailey, gave Angelou her nickname “Maya.”
Response: Maya Angelou, born in 1928 as Marguerite Ann Johnson in St. Louis, Missouri, was a world-famous author, poet, dancer, singer, activist, and scholar who had a unique autobiographical writing style. Because of her parents' rough marriage and eventual divorce, Angelou grew up in Arkansas with her grandparents. 

Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context. 

Store the generated pairs in valid JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance: 

{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]} 

Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.

Summarize the significance of the discovery of penicillin. Penicillin, discovered by Alexander Fleming in 1928, is considered one of the most important discoveries in medical history. Fleming observed that a mold called Penicillium notatum could kill a wide range of bacteria. This discovery led to the development of antibiotics, revolutionizing the treatment of bacterial infections and saving countless lives. Before antibiotics, there were no effective treatments for many common infections, which often led to severe illness or death. The widespread use of penicillin during World War II significantly reduced death rates from infected wounds.
user
Alexander Fleming's 1928 discovery of penicillin revolutionized medicine by introducing antibiotics, drastically improving the treatment of bacterial infections. This breakthrough saved countless lives and significantly reduced wartime mortality from infected wounds, highlighting its vast significance in medical history.
assistant