1 2 3 4 5 6 7 8 whqlibdoc.who.int (PDF). World Health Organization. 1 2 3 4 5 6 7 8 9 10 Diarrhoeal disease Fact sheet N°330. World Health Organization. April 2013. Retrieved 9 July 2014. 1 2 Basem Abdelmalak; John Doyle, eds. (2013). Anesthesia for otolaryngologic surgery. Cambridge University Press. pp.xa0282–287. ISBNxa01107018676. 1 2 3 4 DuPont HL (Apr 17, 2014). Acute infectious diarrhea in immunocompetent adults.. The New England Journal of Medicine 370 (16): 1532–40. doi:10.1056/nejmra1301069. PMIDxa024738670. ↑ Prober, edited by Sarah Long, Larry Pickering, Charles G. (2012). Principles and practice of pediatric infectious diseases (4th ed.). Edinburgh: Elsevier Saunders. p.xa096. ISBNxa09781455739851. ↑ ACEP. Nations Emergency Physicians Announce List of Test and Procedures to Question as Part of Choosing Wisely Campaign. Choosing Wisely. Retrieved 18 June 2014. ↑ Global Burden of Disease Study 2013, Collaborators (22 August 2015). Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.. Lancet (London, England) 386 (9995): 743–800. doi:10.1016/s0140-6736(15)60692-4. PMIDxa026063472. ↑ GBD 2013 Mortality and Causes of Death, Collaborators (17 December 2014). Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.. Lancet 385 (9963): 117–71. doi:10.1016/S0140-6736(14)61682-2. PMCxa04340604. PMIDxa025530442. 1 2 Global Diarrhea Burden. CDC. January 24, 2013. Retrieved 18 June 2014. ↑ WGO Practice Guideline - Acute diarrhea. Retrieved 9 March 2011. 1 2 3 The Basics of Diarrhea. Webmd.com. 17 February 2011. Retrieved 9 March 2011. 1 2 3 4 5 6 7 8 9 10 The Treatment Of Diarrhea, A manual for physicians and other senior health workers (PDF). Sometimes needs to be downloaded twice. See 4.2 Treatment Plan A: home therapy to prevent dehydration and malnutrition, 4.3 Treatment Plan B: oral rehydration therapy for children with some dehydration, and 4.4 Treatment Plan C: for patients with severe dehydration on pages 8 to 16 (12–20 in PDF). See also 8. Management of Diarrhoea with Severe Malnutrition on pages 22–24 (26–30 in PDF) and Annex 2: Oral and Intravenous Rehydration Solutions on pages 33–37 (37–41 in PDF). World Health Organization. 2005. 1 2 Disease Control Priorities Project. Public Health Significance of Diarrheal Illnesses. The World Bank Group. Retrieved 12 October 2013. ↑ Guerrant RL, Schorling JB, McAuliffe JF, de Souza MA (July 1992). Diarrhea as a cause and an effect of malnutrition: diarrhea prevents catch-up growth and malnutrition increases diarrhea frequency and duration. The American journal of tropical medicine and hygiene 47 (1 Pt 2): 28–35. PMIDxa01632474. ↑ Grantham-McGregor SM, Walker SP, Chang S (February 2000). Nutritional deficiencies and later behavioural development. The Proceedings of the Nutrition Society 59 (1): 47–54. doi:10.1017/S0029665100000069. PMIDxa010828173. 1 2 Wilson ME (December 2005). Diarrhea in nontravelers: risk and etiology. Clin. Infect. Dis. 41 41 (Suppl 8): S541–6. doi:10.1086/432949. PMIDxa016267716. ↑ Navaneethan U, Giannella RA (November 2008). Mechanisms of infectious diarrhea. Nature Clinical Practice Gastroenterology & Hepatology 5 (11): 637–47. doi:10.1038/ncpgasthep1264. PMIDxa018813221. ↑ David Schlossberg (2008). Clinical Infectious Disease. Cambridge University Press. p.xa0349. ISBNxa09781139576659. ↑ Patel MM, Hall AJ, Vinjé J, Parashar UD (January 2009). Noroviruses: a comprehensive review. Journal of Clinical Virology 44 (1): 1–8. doi:10.1016/j.jcv.2008.10.009. PMIDxa019084472. ↑ Greenberg HB, Estes MK (May 2009). Rotaviruses: from pathogenesis to vaccination. Gastroenterology 136 (6): 1939–51. doi:10.1053/j.gastro.2009.02.076. PMCxa03690811. PMIDxa019457420. ↑ Uhnoo I, Svensson L, Wadell G (September 1990). Enteric adenoviruses. Baillières Clinical Gastroenterology 4 (3): 627–42. doi:10.1016/0950-3528(90)90053-J. PMIDxa01962727. ↑ Mitchell DK (November 2002). Astrovirus gastroenteritis. The Pediatric Infectious Disease Journal 21 (11): 1067–9. doi:10.1097/01.inf.0000036683.11146.c7 (inactive 2015-01-12). PMIDxa012442031. ↑ Viswanathan VK, Hodges K, Hecht G (February 2009). Enteric infection meets intestinal function: how bacterial pathogens cause diarrhoea. Nature Reviews Microbiology 7 (2): 110–9. doi:10.1038/nrmicro2053. PMCxa03326399. PMIDxa019116615. ↑ Rupnik M, Wilcox MH, Gerding DN (July 2009). Clostridium difficile infection: new developments in epidemiology and pathogenesis. Nature Reviews Microbiology 7 (7): 526–36. doi:10.1038/nrmicro2164. PMIDxa019528959. ↑ Rossignol JF, Lopez-Chegne N, Julcamoro LM, Carrion ME, Bardin MC (2012). Nitazoxanide for the empiric treatment of pediatric infectious diarrhea. Trans. R. Soc. Trop. Med. Hyg. 106 (3): 167–73. doi:10.1016/j.trstmh.2011.11.007. PMIDxa022301075. ↑ Alam NH, Ashraf H (2003). Treatment of infectious diarrhea in children. Paediatr Drugs 5 (3): 151–65. doi:10.2165/00128072-200305030-00002. PMIDxa012608880. ↑ Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC (2006). Functional bowel disorders. Gastroenterology 130 (5): 1480–91. doi:10.1053/j.gastro.2005.11.061. PMIDxa016678561. ↑ Wedlake L, AHern R, Russell D, Thomas K, Walters JR, Andreyev HJ (2009). Systematic review: the prevalence of idiopathic bile acid malabsorption as diagnosed by SeHCAT scanning in patients with diarrhoea-predominant irritable bowel syndrome. Alimentary pharmacology & therapeutics 30 (7): 707–17. doi:10.1111/j.1365-2036.2009.04081.x. PMIDxa019570102. ↑ Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, Jameson JL. Harrisons Principles of Internal Medicine. New York: McGraw-Hill, 2005. ISBN 0-07-139140-1. ↑ WHO _BAR_ Diarrhoeal disease. Who.int. Retrieved 2014-03-10. ↑ Jamison, Dean T. (2006). Disease control priorities in developing countries (2nd ed.). New York: Oxford Univ. Press. ISBNxa00821361791. 1 2 Brown J, Cairncross S, Ensink JH (August 2013). Water, sanitation, hygiene and enteric infections in children. Archives of Disease in Childhood 98 (8): 629–34. doi:10.1136/archdischild-2011-301528. PMCxa03717778. PMIDxa023761692. ↑ Black RE, Sazawal S (May 2001). Zinc and childhood infectious disease morbidity and mortality. The British journal of nutrition. 85 Suppl 2: S125–9. doi:10.1079/bjn2000304. PMIDxa011509100. ↑ Shankar AH, Prasad AS (August 1998). Zinc and immune function: the biological basis of altered resistance to infection. The American Journal of Clinical Nutrition 68 (2 Suppl): 447S–463S. PMIDxa09701160. ↑ Bahl R, Bhandari N, Hambidge KM, Bhan MK (August 1998). Plasma zinc as a predictor of diarrheal and respiratory morbidity in children in an urban slum setting. The American Journal of Clinical Nutrition 68 (2 Suppl): 414S–417S. PMIDxa09701154. ↑ Rice, Amy L. Comparative quantification of health risks. WHO. pp.xa0238–240. ↑ Sommer A, Katz J, Tarwotjo I (November 1984). Increased risk of respiratory disease and diarrhea in children with preexisting mild vitamin A deficiency. The American Journal of Clinical Nutrition 40 (5): 1090–5. PMIDxa06496388. ↑ West KP (September 2002). Extent of vitamin A deficiency among preschool children and women of reproductive age. The Journal of Nutrition 132 (9 Suppl): 2857S–2866S. PMIDxa012221262. ↑ Williams, George; Nesse, Randolph M. (1996). Why we get sick: the new science of Darwinian medicine. New York: Vintage Books. pp.xa036–38. ISBNxa00-679-74674-9. ↑ DuPont HL, Hornick RB (December 1973). Adverse effect of lomotil therapy in shigellosis. JAMA 226 (13): 1525–8. doi:10.1001/jama.226.13.1525. PMIDxa04587313. ↑ Ruuska T, Vesikari T (1990). Rotavirus disease in Finnish children: use of numerical scores for clinical severity of diarrhoeal episodes. Scand. J. Infect. Dis. 22 (3): 259–67. doi:10.3109/00365549009027046. PMIDxa02371542. 1 2 Wolf, Jennyfer; Prüss-Ustün, Annette; Cumming, Oliver; Bartram, Jamie; Bonjour, Sophie; Cairncross, Sandy; Clasen, Thomas; Colford, John M.; Curtis, Valerie; De France, Jennifer; Fewtrell, Lorna; Freeman, Matthew C.; Gordon, Bruce; Hunter, Paul R.; Jeandron, Aurelie; Johnston, Richard B.; Mäusezahl, Daniel; Mathers, Colin; Neira, Maria; Higgins, Julian P. T. (August 2014). Systematic review: Assessing the impact of drinking water and sanitation on diarrhoeal disease in low- and middle-income settings: systematic review and meta-regression. Tropical Medicine & International Health 19 (8): 928–942. doi:10.1111/tmi.12331. ↑ Ejemot RI, Ehiri JE, Meremikwu MM, Critchley JA (2008). Ejemot RI, ed. Hand washing for preventing diarrhoea. Cochrane Database Syst Rev (1): CD004265. doi:10.1002/14651858.CD004265.pub2. PMIDxa018254044. 1 2 Call to action on sanitation (pdf). United Nations. Retrieved 15 August 2014. ↑ Open Defecation and Childhood Stunting in India: An Ecological Analysis of New Data from 112 Districts. PLoS ONE (Plos One) 8: e73784. doi:10.1371/journal.pone.0073784. Retrieved 2014-03-10. ↑ Curtis V, Cairncross S (May 2003). Effect of washing hands with soap on diarrhoea risk in the community: a systematic review. The Lancet infectious diseases 3 (5): 275–81. doi:10.1016/S1473-3099(03)00606-6. PMIDxa012726975. ↑ Cairncross S, Hunt C, Boisson S, Bostoen K, Curtis V, Fung IC, Schmidt WP (April 2010). Water, sanitation and hygiene for the prevention of diarrhoea. International Journal of Epidemiology. 39 Suppl 1 (Suppl 1): i193–205. doi:10.1093/ije/dyq035. PMCxa02845874. PMIDxa020348121. ↑ Diarrheal Diseases in Less Developed Countries. CDC. Retrieved 28 October 2013. ↑ Black RE, Morris SS, Bryce J (Jun 28, 2003). Where and why are 10 million children dying every year?. Lancet 361 (9376): 2226–34. doi:10.1016/S0140-6736(03)13779-8. PMIDxa012842379. ↑ Esrey SA, Feachem RG, Hughes JM (1985). Interventions for the control of diarrhoeal diseases among young children: improving water supplies and excreta disposal facilities. Bulletin of the World Health Organization 63 (4): 757–72. PMCxa02536385. PMIDxa03878742. ↑ Arnold BF, Colford JM (February 2007). Treating water with chlorine at point-of-use to improve water quality and reduce child diarrhea in developing countries: a systematic review and meta-analysis. The American journal of tropical medicine and hygiene 76 (2): 354–64. PMIDxa017297049. ↑ de Zoysa I, Feachem RG (1985). Interventions for the control of diarrhoeal diseases among young children: rotavirus and cholera immunization. Bulletin of the World Health Organization 63 (3): 569–83. PMCxa02536413. PMIDxa03876173. ↑ Rheingans RD, Antil L, Dreibelbis R, Podewils LJ, Bresee JS, Parashar UD (Nov 1, 2009). Economic costs of rotavirus gastroenteritis and cost-effectiveness of vaccination in developing countries. The Journal of Infectious Diseases. 200 Suppl 1: S16–27. doi:10.1086/605026 (inactive 2015-01-12). PMIDxa019817595. ↑ Oral cholera vaccines in mass immunization campaigns (PDF). WHO. 2010. pp.xa06–8. ISBNxa0978 92 4 150043 2. ↑ Black RE (May 2003). Zinc deficiency, infectious disease and mortality in the developing world. The Journal of Nutrition 133 (5 Suppl 1): 1485S–9S. PMIDxa012730449. ↑ Bhutta ZA, Black RE, Brown KH, Gardner JM, Gore S, Hidayat A, Khatun F, Martorell R, Ninh NX, Penny ME, Rosado JL, Roy SK, Ruel M, Sazawal S, Shankar A (December 1999). Prevention of diarrhea and pneumonia by zinc supplementation in children in developing countries: pooled analysis of randomized controlled trials. Zinc Investigators Collaborative Group. The Journal of Pediatrics 135 (6): 689–97. doi:10.1016/S0022-3476(99)70086-7. PMIDxa010586170. ↑ Mayo-Wilson E, Imdad A, Herzer K, Yakoob MY, Bhutta ZA (Aug 25, 2011). Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis. BMJ (Clinical research ed.) 343: d5094. doi:10.1136/bmj.d5094 (inactive 2015-01-12). PMCxa03162042. PMIDxa021868478. ↑ Chhagan MK, Van den Broeck J, Luabeya KK, Mpontshane N, Bennish ML (Aug 12, 2013). Cost of childhood diarrhoea in rural South Africa: exploring cost-effectiveness of universal zinc supplementation. Public health nutrition 17 (9): 1–8. doi:10.1017/S1368980013002152. PMIDxa023930984. ↑ Effect of breastfeeding on infant and child mortality due to infectious diseases in less developed countries: a pooled analysis. WHO Collaborative Study Team on the Role of Breastfeeding on the Prevention of Infant Mortality. The Lancet 355 (9202): 451–5. Feb 2000. doi:10.1016/S0140-6736(00)82011-5. PMIDxa010841125. ↑ Sguassero Y. Optimal duration of exclusive breastfeeding: RHL commentary. WHO. Retrieved 14 October 2013. ↑ Hempel S, Newberry SJ, Maher AR, Wang Z, Miles JN, Shanman R, Johnsen B, Shekelle PG (9 May 2012). Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis. JAMA: The Journal of the American Medical Association 307 (18): 1959–69. doi:10.1001/jama.2012.3507 (inactive 2015-01-12). PMIDxa022570464. ↑ King CK, Glass R, Bresee JS, Duggan C (November 2003). Managing acute gastroenteritis among children: oral rehydration, maintenance, and nutritional therapy. MMWR Recomm Rep 52 (RR–16): 1–16. PMIDxa014627948. ↑ BestBets: Does Withholding milk feeds reduce the duration of diarrhoea in children with acute gastroenteritis?. 1 2 3 Community Health Worker Training Materials for Cholera Prevention and Control, CDC, slides at back are dated 17 November 2010. Page 7 states  . . . Continue to breastfeed your baby if the baby has watery diarrhea, even when traveling to get treatment. Adults and older children should continue to eat frequently. ↑ Schiller LR (2007). Management of diarrhea in clinical practice: strategies for primary care physicians. Rev Gastroenterol Disord 7 (Suppl 3): S27–38. PMIDxa018192963. ↑ A Guide on Safe Food for Travellers, Welcome to South Africa, Host to the 2010 FIFA World Cup (bottom left of page 1). 1 2 Rehydration Project, http://rehydrate.org/ Homemade Oral Rehydration Solution Recipe. 1 2 Management of acute diarrhoea and vomiting due to gastoenteritis in children under 5. National Institute of Clinical Excellence. April 2009. ↑ Webb A, Starr M (April 2005). Acute gastroenteritis in children. Australian family physician 34 (4): 227–31. PMIDxa015861741. ↑ MacGillivray S, Fahey T, McGuire W (31 October 2013). Lactose avoidance for young children with acute diarrhoea.. The Cochrane database of systematic reviews 10: CD005433. doi:10.1002/14651858.CD005433.pub2. PMIDxa024173771. ↑ Dryden MS, Gabb RJ, Wright SK (June 1996). Empirical treatment of severe acute community-acquired gastroenteritis with ciprofloxacin. Clin. Infect. Dis. 22 (6): 1019–25. doi:10.1093/clinids/22.6.1019. PMIDxa08783703. 1 2 de Bruyn G (2008). Diarrhoea in adults (acute). Clin Evid (Online) 2008: 0901. PMCxa02907942. PMIDxa019450323. ↑ Wong CS, Jelacic S, Habeeb RL, Watkins SL, Tarr PI (June 2000). The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections. N. Engl. J. Med. 342 (26): 1930–6. doi:10.1056/NEJM200006293422601. PMCxa03659814. PMIDxa010874060. ↑ Diarrhoeal Diseases. World Health Organization. February 2009. ↑ DuPont HL, Ericsson CD, Farthing MJ, Gorbach S, Pickering LK, Rombo L, Steffen R, Weinke T (2009). Expert review of the evidence base for self-therapy of travelers diarrhea. J Travel Med 16 (3): 161–71. doi:10.1111/j.1708-8305.2009.00300.x. PMIDxa019538576. ↑ Pawlowski SW, Warren CA, Guerrant R (May 2009). Diagnosis and treatment of acute or persistent diarrhea. Gastroenterology 136 (6): 1874–86. doi:10.1053/j.gastro.2009.02.072 (inactive 2015-01-12). PMCxa02723735. PMIDxa019457416. ↑ Lazzerini M, Ronfani L (Jan 31, 2013). Oral zinc for treating diarrhoea in children. The Cochrane database of systematic reviews 1: CD005436. doi:10.1002/14651858.CD005436.pub4 (inactive 2015-01-12). PMIDxa023440801. ↑ Allen SJ, Martinez EG, Gregorio GV, Dans LF (2010). Allen SJ, ed. Probiotics for treating acute infectious diarrhoea. Cochrane Database Syst Rev 2010 (11): CD003048. doi:10.1002/14651858.CD003048.pub3 (inactive 2015-01-12). PMIDxa021069673. ↑ Kale-Pradhan PB, Jassal HK, Wilhelm SM (February 2010). Role of Lactobacillus in the prevention of antibiotic-associated diarrhea: a meta-analysis. Pharmacotherapy 30 (2): 119–26. doi:10.1592/phco.30.2.119. PMIDxa020099986. ↑ Mortality and Burden of Disease Estimates for WHO Member States in 2004 (xls). World Health Organization. ↑ Mandell, Gerald L.; Bennett, John E.; Dolin, Raphael (2004). Mandells Principles and Practices of Infection Diseases (6th ed.). Churchill Livingstone. ISBNxa00-443-06643-4. ↑ Diarrhoea: why children are still dying and what can be done (PDF). WHO. WHO. Retrieved 12 October 2013. ↑ Walker CL, Rudan I, Liu L, Nair H, Theodoratou E, Bhutta ZA, OBrien KL, Campbell H, Black RE (Apr 20, 2013). Global burden of childhood pneumonia and diarrhoea. Lancet 381 (9875): 1405–16. doi:10.1016/S0140-6736(13)60222-6. PMIDxa023582727. ↑ Walker CL, Aryee MJ, Boschi-Pinto C, Black RE (2012). Myer L, ed. Estimating diarrhea mortality among young children in low and middle income countries. PLoS ONE 7 (1): e29151. Bibcode:2012PLoSO...729151F. doi:10.1371/journal.pone.0029151. PMCxa03250411. PMIDxa022235266. ↑ Kosek M, Bern C, Guerrant RL (2003). The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000. Bulletin of the World Health Organization 81 (3): 197–204. PMCxa02572419. PMIDxa012764516.