Wɔ woo Akuffo-Addo wɔ June da ɛtɔ so 26, afe 1906 wɔ Dodowa a ɛwɔ Nkran Mantam no mu a n’awofo ne William Martin Addo-danquah ne Theodora Amuafi. N’awofo no mienu nyinaa firi Ghana Apuei fam a ɛne Akropong. ɔhyɛɛ sukuu ase wɔ Presbyterian Primary and Middle Schools wɔ Akropong. Wɔ afe 1929 mu no, ɔkɔɔ Achimota College beae a onyaa nwomanimfo abasobɔ de kɔɔ St. Pters College, Oxford; okosuaa nkontabuo, amanyɔsɛm ne ne Nyansapɛ. Owie sukuu no ma no nyaa abodin krtaa wɔ Nyansapɛ ne Amanyɔsɛm mu wɔ afe 1933.