Biotin carboxyl carrier protein

Biotin Carboxyl Carrier Protein (BCCP) refers to proteins containing a biotin attachment domain that carry biotin and carboxybiotin throughout the ATP-dependent carboxylation by biotin-dependent carboxylases. In the case of "E. coli" Acetyl-CoA carboxylase, the BCCP is a separate protein known as "accB" (). On the other hand, in "Haloferax mediterranei" Propionyl-CoA carboxylase, the BCCP "pccA" () is fused with biotin carboxylase.