Desmethoxyyangonin

Desmethoxyyangonin or 5,6-dehydrokavain is one of the six main kavalactones found in the "Piper methysticum" (kava) plant.
Pharmacology.
Desmethoxyyangonin is a reversible inhibitor of monoamine oxidase B (MAO-B). Kava is able to increase dopamine levels in the nucleus accumbens and desmethoxyyangonin likely contributes to this effect. This, along with several other catecholamines, may be responsible for the purported attention-promoting effects of kava.
Desmethoxyyangonin has marked activity on the induction of CYP3A23.