ARID1B

AT-rich interactive domain-containing protein 1B is a protein that in humans is encoded by the "ARID1B" gene. ARID1B is a component of the human SWI/SNF chromatin remodeling complex.
Clinical significance.
Germline mutations in ARID1B are associated with Coffin-Siris syndrome. Somatic mutations in ARID1B are associated with several cancer subtypes, suggesting that it is a tumor suppressor gene.
Interactions.
ARID1B has been shown to interact with SMARCA4 and SMARCA2.