Nucleocidin

Nucleocidin is a fluorine-containing nucleoside produced by "Streptomyces calvus".
During 1968 the attempts to identify nucleocidin were made and at that time it was assigned to a structure of a 9-adenyl-4"'" -sulfamoyloxypentofuranoside, which was mainly based on experiments from pmr and mass spectroscopy, as well as testing in chemical reactions. It was ultimately proven to have a structure of a 4""' -fluoro-5"' -O"-sulphamoyladenosine. Nucleocidin is an antibiotic that can be produced from "Streptomyces calvus" that grows on Indian land. It is essentially toxic for mammals, although nucleocidin is able to function against a bacteria, such as gram negative, and gram positive. Moreover it can be used against trypanosomes.