Flumetasone

Flumetasone, also known as flumethasone, is a corticosteroid for topical use.
It was patented in 1951 and approved for medical use in 1964.
Chemistry.
Flumethasone is 420 times as potent as cortisone in an animal model for anti-inflammatory activity.
Names.
Trade names include Locacorten, Locorten, and Orsalin. It is available in combination with clioquinol, under the trade name Locacorten-Vioform (in some countries Locorten-Vioform), for the treatment of otitis externa and otomycosis. It is usually formulated as the pivalic acid ester prodrug called flumetasone pivalate.