Clostripain

Clostripain (, "clostridiopeptidase B", "clostridium histolyticum proteinase B", "alpha-clostridipain", "clostridiopeptidase", "Endoproteinase Arg-C") is a proteinase that cleaves proteins on the carboxyl peptide bond of arginine. It was isolated from "Clostridium histolyticum". The isoelectric point of the enzyme is 4.8-4.9 (at 8 °C), and optimum pH is 7.4~7.8 (against α-benzoyl-arginine ethyl ester). The composition of the enzyme is indicated to be of two chains of relative molecular mass 45,000 and 12,500.