Anion exchange protein 3

Anion exchange protein 3 is a membrane transport protein that in humans is encoded by the "SLC4A3" gene. AE3 is functionally similar to the Band 3 Cl−/HCO3− exchange protein but it is expressed primarily in brain neurons and in the heart. Like AE2 its activity is sensitive to pH. AE3 mutations have been linked to seizures.