
Mycobacterium bohemicum

Mycobacterium bohemicum is a species of the phylum Actinobacteria (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus "Mycobacterium".
Mycobacterium bohemicum is a nontuberculous bacterium that has been isolated from human tissue, animals, and the environment. "M. bohemicum" affects soft tissue in animal cells. "Mycobacterium bohemicum" was identified in 1998 when isolated from sputum that was produced by a 53-year-old Down's Syndrome patient with tuberculosis "M. bohemicum" has been reported and documented in 9 patients worldwide. Reports of the bacterium have been recorded from Finland and Austria. In children, "M. bohemicum" has induced laterocervical and submandibular lymphadenitis. The excision of the subjects lymph nodes along with antimicrobial therapy increased the health of the subjects in less than 12 months.
The lymph nodes of the subjects were minced and stained according to the Ziehl–Neelsen technique. Within 12–17 days a culture was produced that could be analyzed on a molecular level "Richter". "M. bohemicum" contains combinations of α-, keto-, metoxy-, and dicarboxy-mycolates that are not commonly found in slow-growing bacteria[3] . Other distinct characteristics of "M. bohemicum" is identifiable by its unique 16S rDNA nucleotide sequence as well as its variation in the ITS sequence region of 16S-23S.
Genotypic Features.
Type strain: strain CIP 105808 = CIP 105811 = DSM 44277 = JCM 12402