Topilutamide

Topilutamide, known more commonly as fluridil and sold under the brand name Eucapil, is an antiandrogen medication which is used in the treatment of pattern hair loss in men and women. It is used as a topical medication and is applied to the scalp.
Topilutamide is a nonsteroidal antiandrogen (NSAA), or an antagonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT).
Topilutamide was introduced for medical use in 2003. It is marketed only in the Czech Republic and Slovakia.
Medical uses.
Topilutamide is used as a topical medication in the treatment of pattern hair loss in men and women.
Available forms.
As Eucapil, topilutamide is available as a 2% topical formulation intended for application to the scalp.
Pharmacology.
Pharmacodynamics.
Topilutamide is an antagonist of the AR, the biological target of androgens like testosterone and DHT.
Pharmacokinetics.
Topilutamide is a topical medication and is applied to the scalp.
Chemistry.
Topilutamide is a nonsteroidal compound and is closely related to other NSAAs such as flutamide and bicalutamide.
History.
Topilutamide was introduced for medical use in 2003.
Society and culture.
Generic names.
"Topilutamide" is the generic name of the drug and its . It is also known more commonly as "fluridil". Topilutamide is also known by its former developmental code name "BP-766".
Brand names.
Topilutamide is marketed by Interpharma Praha under the brand name Eucapil.
Availability.
Topilutamide is available only in Europe in the Czech Republic and Slovakia.