MSC (gene)

Musculin is a protein that in humans is encoded by the "MSC" gene.
The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A "in vitro". The encoded protein also forms heterodimers with E2A proteins "in vivo". This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway.