GPAT4

Glycerol-3-phosphate acyltransferase 4 is a protein that in humans is encoded by the GPAT4 gene.
Function.
GPAT4 is involved in the biosynthesis of triglycerides. The majority of triglycerides are synthesised from glycerol 3-phosphate (G3P) via the addition of three fatty acyl-CoA substrates, which are made from fatty acids. The first of these additions is catalysed by G3P acyltransferases (GPATs: EC 2.3.1.15), including GPAT4, yielding lysophosphatidic acid. GPAT4 has been shown to be important for lactation, with QTL for several milk production and composition traits observed at this locus in cattle.