EIF3D

Eukaryotic translation initiation factor 3 subunit D (eIF3d) is a protein that in humans is encoded by the "EIF3D" gene.
Function.
Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex.
Interactions.
EIF3D has been shown to interact with PHLDA1 and EIF3A.