C5orf45

Chromosome 5 open reading frame 45 is a protein that in humans is encoded by the "C5orf45" gene. The orthologue in mice is "3010026O09Rik".
Model organisms.
Model organisms have been used in the study of "C5orf45" function. A conditional knockout mouse line, called "3010026O09Riktm1a(EUCOMM)Wtsi" was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.
Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty five tests were carried out on mutant mice and one significant abnormality was observed: male homozygote mutants were infertile.