LRSAM1

E3 ubiquitin-protein ligase LRSAM1, previously known as Tsg101-associated ligase (Tal), is an enzyme that in humans is encoded by the "LRSAM1" gene.
Clinical significance.
Mutations in "LRSAM1" have been reported in the peripheral neuropathy Charcot-Marie-Tooth type 2P (OMIM 614436), while disruption of the mouse "Lrsam1" gene has been shown to sensitize peripheral axons to acrylamide-induced degeneration.
Interactions.
LRSAM1 has been shown to interact with TSG101.