SEL1L

Protein sel-1 homolog 1 is a protein that in humans is encoded by the "SEL1L" gene.
Clinical relevance.
A mutation in this gene in Finnish Hound dogs have been implicated in cases of cerebellar ataxia.<ref name="doi.10.1371/journal.pgen.1002759"></ref> Mutant cells suffer disruptions in their endoplasmic reticula, leading to disease.