CYB561

Cytochrome b561 is a protein that in humans is encoded by the "CYB561" gene.
Model organisms.
Model organisms have been used in the study of CYB561 function. A conditional knockout mouse line, called "Cyb561tm1a(EUCOMM)Wtsi" was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.
Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty three tests were carried out on mutant mice and one significant abnormality was observed: female homozygotes displayed a decreased circulating glucose level after a glucose tolerance test.