AP4B1

AP-4 complex subunit beta-1 is a protein that in humans is encoded by the "AP4B1" gene.
Function.
The heterotetrameric adaptor protein (AP) complexes sort integral membrane proteins at various stages of the endocytic and secretory pathways. AP4 is composed of 2 large chains, beta-4 (AP4B1, this protein) and epsilon-4 (AP4E1), a medium chain, mu-4 (AP4M1), and a small chain, sigma-4 (AP4S1)
Interactions.
AP4B1 has been shown to interact with AP4M1.
Clinical relevance.
AP4-complex-mediated trafficking plays a crucial role in brain development and functioning.