Karnovsky fixative

Karnovsky fixative, developed by M. J. Karnovsky, is a fixative for electron microscopy.
Solution.
The stock solution for Karnovsky fixative is as follows:
Modified solutions.
Karnovsky's fixative solution is often modified for specialized applications. For example, 2% paraformaldehyde, 2.5% glutaraldehyde in 0.1 Molar sodium phosphate buffer (pH 7.4) has been used to study the ultrastructure of renal pelvis fragments.