GRAP

GRB2-related adapter protein is a protein that in humans is encoded by the "GRAP" gene.
This gene encodes a member of the GRB2/Sem5 ("C. elegans" homolog)/Drk ("Drosophila" homolog) family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.
Interactions.
GRAP has been shown to interact with Linker of activated T cells.