DNPEP

Aspartyl aminopeptidase is an enzyme that in humans is encoded by the "DNPEP" gene.
Function.
The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in general metabolism of intracellular proteins.
Model organisms.
Model organisms have been used in the study of DNPEP function. A conditional knockout mouse line called "Dnpeptm1e(EUCOMM)Wtsi" was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: In-depth immunological phenotyping.