Scientific International Research in Unique Terrestrial Station

Scientific International Research in Unique Terrestrial Station (SIRIUS) is a series of experiments that investigate the effects of isolation and simulates a flight to the moon at the Institute of Biomedical Problems (IBMP) in Moscow, Russia. The first of the series started in 2017. Following the 2019 122-day experiment will be an eight-month experiment in 2020, and a twelve-month experiment in 2021 in which the European Space Agency will participate.
SIRIUS-17.
7-24 November 2017. The first of the series of joint Russian-US SIRIUS experiments in which NASA's Human Research Program and IBMP conducted research to identify preventive measures and technologies to protect the health of astronauts during spaceflight, it lasted 17 days. The 6 person crew conducted over 60 experiments, "captured" satellites using a manipulator arm and controlled a rover on the Moon's surface. One experiment consisted of 38-hours of sleep deprivation, during which crew members had to perform a manual VR-simulated docking of the planned Orel spacecraft with a booster rocket in Earth's orbit.
SIRIUS-19.
Commenced 19 March 2019 at the NEK ground based facility at IBMP. The crew will carry out over 80 experiments and halfway through there will be a simulated visit to the moon, four crew members will "land on the lunar surface" in a small capsule and will carry out several "moonwalks" while wearing spacesuits, they will also collect samples and prepare a "settlement". Two members of the crew will remain behind in the simulated Lunar Gateway and monitor them. After the return and docking of the lander with the simulated Gateway, the whole crew will orbit the moon for 30 days, remotely control rovers on the lunar surface, dock spaceships with the Orbital Platform, and carry out other experiments before their "return to Moscow".
Participants in the study are the German Aerospace Center Deutsches Zentrum für Luft- und Raumfahrt (DLR) Space Administration and the French space agency (CNES), under the leadership of Roscosmos and NASA.