Miss Ann

Miss Ann is an expression used inside the African-American community, to refer to a European-American woman (or sometimes a black woman) who is arrogant and condescending in her attitude.
The characteristics associated with someone called a "Miss Ann" include being considered "uppity", or in the case of a black woman, "acting white". 
Like the male counterpart term, Mister Charlie, the term Miss Ann was once common among many African-Americans. It was a pejorative way of commenting on imperious behaviour from white women, particularly when it came with racist undertones. It is seldom used among young African-Americans today, instead the term “Karen” has come into further usage amongst people of all races in the United States. 
In popular culture.
Miss Anne: “A White Woman”<br>
—Zora Neale Hurston, "Glossary of Harlem Slang"
Ann; Miss Ann: Coded term for any white female. [i.e.] “His mama washes clothes on Wednesday for Miss Ann.”<br>
—Clarence Major, "From Juba to Jive: A Dictionary of African-American Slang"
Ann: (1) A derisive term for a white woman … Also “Miss Ann.”<br>
—Geneva Smitherman, "Black Talk"
Miss Ann and Mister Eddie: Emancipated bluebloods.<br>
—Taylor Gordon, "Born to Be"
"I’d remind them please, look at those knees, you got at Miss Ann’s scrubbing."<br>
–Maya Angelou, "Sepia Fashion Show"
"Oh, oh, oh, Miss Ann, you're doing something no one can…"<br>
–"Miss Ann" song by Little Richard. Here the singer may be referring to the white woman, Ann Johnson, who mothered him as a young teenager, twisting the standard connotation in ambiguous ways.