Monoclonality

Monoclonality is the term describing cells produced from a single ancestral cell by repeated cellular replication. Thus "monoclonal cells" can be said to form a single clone. The term "monoclonal" comes from the Ancient Greek "monos", meaning "alone" or "single", and "klon", meaning "twig".
The process of replication can occur "in vivo", or may be stimulated "in vitro" for laboratory manipulations. The use of the term typically implies that there is some method to distinguish between the cells of the original population from which the single ancestral cell is derived, such as a random genetic alteration, which is inherited by the progeny.
Common usages of this term include: