Inferior pharyngeal constrictor muscle

The Inferior pharyngeal constrictor, the thickest of the three constrictors, arises from the sides of the cricoid and thyroid cartilage. Similarly to the superior and middle pharyngeal constrictor muscles, it is innervated by the vagus nerve (cranial nerve X), specifically, by branches from the pharyngeal plexus and by neuronal branches from the recurrent laryngeal nerve.
Origin and insertion.
The muscle is composed of two parts. The first (and more superior) arising from the thyroid cartilage (thyropharyngeal part) and the second arising from the cricoid cartilage (cricopharyngeal part).
From these origins the fibers spread backward and medialward to be inserted with the muscle of the opposite side into the fibrous pharyngeal raphe in the posterior median line of the pharynx.
The inferior fibers are horizontal and continuous with the circular fibers of the esophagus; the rest ascend, increasing in obliquity, and overlap the Constrictor medius. The cricopharyngeal muscle is synonymous with the upper esophageal sphincter (UES), which controls the opening of the cervical esophagus, and is sometimes referred to as the cricopharyngeal inlet.
Action.
As soon as the bolus of food is received in the pharynx, the elevator muscles relax, the pharynx descends, and the constrictors contract upon the bolus, and convey it downward into the esophagus. During deglutition, they contract and cause peristaltic movement in the pharynx.
Role in human disease.
Uncoordinated contraction, and/or Cricopharyngeal Spasm and/or impaired relaxation of this muscle are currently considered the main factors in development of a Zenker's diverticulum. Zenker's diverticulum develops between the two bellies of the inferior constrictor (Thyropharyngeal and Cricopharyngeal) in a small gap called Killian's dehiscence. A diverticulum can form where a balloon of mucosa becomes trapped outside the pharyngeal boundaries. Food or other materials may reside here, which may lead to infection.
Motor incoordination of the cricopharyngeus can cause difficulty swallowing.
In extreme cases this can be related to Retrograde Cricopharyngeus Dysfunction (R-CPD) which causes the inability to burp, this is in part due to the muscle not being able to relax. Botox or a Cricopharyngeal myotomy are used to treat the condition. 