MicC RNA

The MicC non-coding RNA (previously known as IS063 ) is located between the "ompN" and "ydbK" genes in "E. coli". This Hfq-associated RNA is thought to be a regulator of the expression level of the OmpC porin protein, with a 5′ region of 22 nucleotides potentially forming an antisense interaction with the "ompC" mRNA. Along with MicF RNA this family may act in conjunction with EnvZ-OmpR two-component system to control the OmpF/OmpC protein ratio in response to a variety of environmental stimuli. The expression of "micC" was shown to be increased in the presence of beta-lactam antibiotics.