N-Methyltryptamine

"N"-Methyltryptamine (NMT) is a member of the substituted tryptamine chemical class and a natural product which is biosynthesized in the human body from tryptamine by certain N-methyltransferase enzymes, such as indolethylamine "N"-methyltransferase. It is a common component in human urine. NMT is an alkaloid derived from -tryptophan that has been found in the bark, shoots and leaves of several plant genera, including "Virola", "Acacia", "Mimosa", and "Desmanthus"—often together with the related compounds "N","N"-dimethyltryptamine (DMT) and 5-methoxy-"N","N"-dimethyltryptamine (5-MeO-DMT).
Orally administered NMT appears to produce no psychoactive effects, likely as a result of extensive first-pass metabolism. However, it may become active upon combination with a MAOA inhibitor (MAOI).
By vaporization NMT shows activity at 50–100 mg, with a duration of 45–70 minutes; duration of visual effects 15–30 seconds. Effects are primarily non-visual.