Angel and the Ape

Angel and the Ape was a humor comic book created by E. Nelson Bridwell & Bob Oksner published by DC Comics. The characters first appeared in 1968 in "Showcase" #77 then graduated to their own title, with art by comic artist Bob Oksner, most often inked by Wally Wood. The title lasted for seven issues, changing its name to "Meet Angel" for its final appearance.
Series overview.
Angel O'Day is a private investigator who manages the O'Day and Simeon Detective Agency with her partner Sam Simeon. Sam differs from many stereotypical detectives; besides helping Angel, Sam is both a comic book artist and a talking gorilla. Sam's last name is a play on the word "simian" ("of or pertaining to an ape or monkey"). In the first few stories, Sam draws comics for a self-obsessed editor named Stan Bragg, then moves to a competitor, working for Morton Stoops.
Revivals.
The series has been revived twice. The first was by Phil Foglio in the 1990s, where "Angel and the Ape" stuck true to its zany roots. In Phil Foglio's 1991 mini-series, Angel is revealed to be the half-sister of the Dumb Bunny, a member of the super-heroic group the Inferior Five, also created by Bridwell. Sam is changed, too; he is not only employed by "DZ Comics" as an artist, but is also the grandson of Gorilla Grodd, a nemesis of the Flash. As such, Sam has mental powers that he can use to make a limited number of people see him as a human being. However, a break in his concentration allows people to see him in his true form. This is in contrast to the original series, wherein people see Sam's true form but convince themselves he is simply an unusually ape-like human male, since it is "impossible" for there to be such a thing as a talking gorilla.
A second revival was made in early 2001 under DC's Vertigo imprint, with a vastly different take. The four-issue limited series was written by Howard Chaykin and David Tischman, with art by Philip Bond and covers by Arthur Adams.
The two appeared in a one-page story in "DC Holiday Special '09", written and drawn by Andrew Pepoy.
In 2012, they appeared in a segment of the anthology title "Joe Kubert Presents".
Angel and Sam are briefly seen when they sense Miguel Montez using the H-Dial for the first time.
In other media.
Angel O'Day appears in the "Young Justice" episode "Influence", voiced by Danica McKellar.
A variation of Sam Simeon appears in the tie-in comics of "Young Justice". This version is depicted as the son of Gorilla Grodd and Primat.