List of Plymouth Argyle F.C. results by opponent

Plymouth Argyle Football Club are an English professional association football club based in Plymouth, Devon. They compete in Football League Two as of the 2015–16 season, the fourth division of the English football league system. The club was formed in 1886 as Argyle Football Club, a name which was retained until 1903 when the club became professional and were elected to the Southern Football League. The club also entered English football's premier knockout competition, the Football Association Challenge Cup, for the first time that same year. The club joined the Football League in 1920, and have competed there since then, achieving multiple league titles, promotions and relegations.
During this time, Plymouth Argyle's first team has competed in a number of nationally contested leagues and knock-out tournaments. Its record against each club faced in these competitions is listed below, in alphabetical order. The team that Plymouth Argyle have met most in competitive matches is Bristol Rovers, having played 133 matches since 1903. Bristol Rovers also account for the club's record number of victories, 57, and their record number of losses, 41. Brentford are the club that Plymouth Argyle have drawn the most against, with 37 drawn matches out of 118.