3-Galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase

In enzymology, a 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase () is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are GDP-beta-L-fucose and beta-D-galactosyl-(1->3)-N-acetyl-D-glucosaminyl-R, whereas its 3 products are GDP, beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-, and glucosaminyl-R.
This enzyme participates in 3 metabolic pathways: glycosphingolipid biosynthesis - lactoseries, glycosphingolipid biosynthesis - neo-lactoseries, and glycan structures - biosynthesis 2.
Nomenclature.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase. Other names in common use include: