1555 Skopje earthquake

The Skopje earthquake of 1555 was the strongest between 518 and 1963 and caused devastation.
A significant part of Skopje was collapsed and the Old Bazaar, Skopje was severely damaged, as was the Stone Bridge (Skopje), on which four columns were either completely destroyed or seriously damaged. The earthquake also destroyed the murals in the upper parts of the Church of Saint Panteleimon, Gorno Nerezi. 
Consequences.
As a result of the earthquake, Skopje has been almost completely renovated. Participants in its burning in 1689 described it as the most important Ottoman city in the Balkans, comparable to Prague at the time. After being burned in 1689, for security reasons, it rose up as his remake - Moscopole, which was burned in 1769 because of complicity with the instigators of the Orlov revolt. 