HR (gene)

Protein hairless is a protein that in humans is encoded by the "HR" gene.
This gene encodes a protein whose function has been linked to hair growth. A similar protein in rat functions as a transcriptional corepressor for thyroid hormone and interacts with histone deacetylases.
Human Genetics.
Variations in this gene are involved in low levels of hair (baldness / alopecia / hypotrichosis) Mutations in this gene in humans have been documented in cases of autosomal recessive congenital alopecia and atrichia with papular lesions.
The protein contains a Zinc finger domain.