Adenylthiomethylpentose

Adenylthiomethylpentose is a sulfur-containing nucleoside that was formerly known as vitamin L2. This chemical is an intermediate in the methylthioadenosine (MTA) cycle, better known as the methionine salvage pathway that is universal to aerobic life.
In 1912, an adenine nucleoside was isolated by Hunter "et al." from yeast that were grown without phosphorus or sulfur. Later that substance was shown by Levene and Sobotkal to be adenylthiomethylpentose.
In 1936, W. Nakahara "et al." did experiments on rats that suggested that vitamin L2 deficiency inhibits the ability of rats to lactate. In 1942 they identified vitamin L2 to be adenylthiomethylpentose. Later studies by Folley "et al" refuted Nakahara's claims and demonstrated that L is not necessary for lactation and thus L2 is not considered a vitamin today.
Hecht found in 1937 that the body temperature of rabbits, cats and guinea pigs were lowered by 1 to 2 degrees after he gave them adenylthiomethylpentose at a dose of 0.2 g/kg. Kühn "et al." replicated this in guinea pigs in 1941.