(S)-norcoclaurine synthase

In enzymology, a ("S")-norcoclaurine synthase () is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are 4-hydroxyphenylacetaldehyde and 4-(2-aminoethyl)benzene-1,2-diol, whereas its two products are ("S")-norcoclaurine and HO.
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 4-hydroxyphenylacetaldehyde hydro-lyase [adding dopamine ("S")-norcoclaurine-forming]. Other names in common use include ("S")-norlaudanosoline synthase, and 4-hydroxyphenylacetaldehyde hydro-lyase (adding dopamine). This enzyme participates in benzylisoquinoline alkaloid biosynthesis.