Voacamine

Voacamine, also known under the older names voacanginine and vocamine, is a naturally occurring dimeric indole alkaloid of the secologanin type, found in a number of plants, including "Voacanga africana" and "Tabernaemontana divaricata".
It is approved for use as an antimalarial drug in several African countries. Voacamine exhibits cannabinoid CB1 receptor antagonistic activity.
Chemical structure.
There is considerable confusion about the absolute stereochemical configuration of voacamine and the originally published absolute structure had to be later revised.
Adverse Effect.
Voacamine can cause hypertension in high dose.