The Brain Drain

The Brain Drain is a BBC comedy panel show that ran for 2 series in the early 1990s. 
Presented by Jimmy Mulville and featuring a panel of 4 performers (including regular panellists Tony Hawks and (in the 2nd series) Jo Brand), the show was essentially a comedy version of "Question Time". Panellists were asked a question by a member of the studio audience (including occasional celebrity guests) to which they were invited to give a humorous response.